Bio-Erasable Intermolecular Donor–Acceptor Interaction of Organic Semiconducting Nanoprobes for Activatable NIR-II Fluorescence Imaging
Abstract
Abstract Activatable second near‐infrared window (NIR‐II; 1.0–1.7 µm) fluorescence probes that uncage deep‐tissue penetrating fluorescence by disease‐related biomarker stimuli hold great promise for detecting diseases with a poor understanding of the pathology at the molecular level with unprecedented resolution. However, currently, very few activatable NIR‐II fluorescence probes are reported mainly due to the lack of a simple yet general design strategy. Herein, a new and fairly generic design strategy using a bio‐erasable intermolecular donor–acceptor interaction to construct activatable NIR‐II fluorescence probes is reported. An organic semiconducting nanoprobe (SPNP) is constructed through blending a biomarker‐sensitive organic semiconducting non‐fullerene acceptor (3,9‐bis(2‐methylene‐(3‐(1,1‐dicyanomethylene)‐cyclopentane‐1,3‐dione‐[c]thiophen))‐5,5,11,11‐tetrakis(4‐hexylphenyl)‐dithieno[2,3‐d:2',3'‐d']‐s‐indaceno[1,2‐b:5,6‐b'] dithiophene) (ITTC) (one of electric acceptors in organic solar cells) with a biomarker‐inert semiconducting polymer donor 5‐(4,8‐bis((2‐ethylhexyl)oxy)‐6‐methylbenzo[1,2‐b:4,5‐b']difuran‐2‐yl)‐10‐methylnaphtho[1,2‐c:5,6‐c']bis([1,2,5]thiadiazole) (PDF) in an amphiphilic‐polymer‐coated single nanoparticle to suppress NIR‐II fluorescence of the donor via a intermolecular donor–acceptor interaction. The acceptor ITTC is found to be specifically degraded by hypochlorite (an important biomarker) to erase its acceptor property, thus erasing the intermolecular donor–acceptor interaction and uncaging NIR‐II fluorescence. Consequently, SPNP exhibits a 17.5‐fold higher fluorescence brightness in the hypochlorite‐abnormal inflammation in vivo than in normal tissues. Our bio‐erasable intermolecular donor–acceptor interaction strategy provides simple yet general guidelines to design various biomarker‐activatable NIR‐II fluorescence probes.
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After hypochlorite degraded the acceptor ITTC, the interaction disappeared, and the NIR-II fluorescence restored.
“It was proposed that hypochlorite can degrade the acceptor ITTC (Figure 13c). After that, the interaction disappeared, and the NIR-II fluorescence restored.”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [196]
Fan's group described a new method to construct a smart NIR-II probe using the bioerasable intermolecular donor-acceptor interaction.
“Fan’s group described a new method to construct a smart NIR-II probe using the bioerasable intermolecular donor–acceptor interaction [196].”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [196]
The fluorescence of conjugated polymers was quenched likely due to the strong donor-acceptor interaction.
“The fluorescence of conjugated polymers was quenched likely due to the strong doner–acceptor interaction.”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [196]
The donor semiconducting polymer and acceptor nonfullerene (ITTC) were accurately coated with an amphiphilic polymer in aqueous solution.
“The donor semiconducting polymer and acceptor nonfullerene (ITTC) were accurately coated with an amphiphilic polymer in aqueous solution.”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [196]
Cites
Organic solar cells based on non-fullerene acceptors
Hou, J., Inganäs, O., Friend, R. H., & Gao, F. (2018) · Nature Materials · doi:10.1038/nmat5063 · Cited by 2,874 · see citing works
Second window for in vivo imaging
Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848 · see citing works
Non-fullerene acceptors for organic solar cells
Yan, C., Barlow, S. H., Wang, Z., Yan, H., Jen, A. K. ‐., Marder, S. R., & Zhan, X. (2018) · Nature Reviews Materials · doi:10.1038/natrevmats.2018.3 · Cited by 2,724 · see citing works
A small-molecule dye for NIR-II imaging
Antaris, A. L., Chen, H., Cheng, K., Sun, Y., Hong, G., Qu, C., Diao, S., Deng, Z., Hu, X., Zhang, B., et al. (2016) · Nature Materials · doi:10.1038/nmat4476 · Cited by 1,778 · see citing works
Self-citationSemiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice
Pu, K., Shuhendler, A. J., Jokerst, J. V., Mei, J., Gambhir, S. S., Bao, Z., & Rao, J. (2014) · Nature Nanotechnology · doi:10.1038/nnano.2013.302 · Cited by 1,185 · see citing works
Through-skull fluorescence imaging of the brain in a new near-infrared window
Hong, G., Diao, S., Chang, J., Antaris, A. L., Chen, C., Zhang, B., Zhao, S., Atochin, D. N., Huang, P. L., Andreasson, K. I., et al. (2014) · Nature Photonics · doi:10.1038/nphoton.2014.166 · Cited by 1,052 · see citing works
He, S., Song, J., Qu, J., & Cheng, Z. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00234g · Cited by 1,021 · see citing works
Molecular afterglow imaging with bright, biodegradable polymer nanoparticles
Miao, Q., Xie, C., Xu, Z. J., Lyu, Y., Duan, H., Liu, X., Jokerst, J. V., & Pu, K. (2017) · Nature Biotechnology · doi:10.1038/nbt.3987 · Cited by 979 · see citing works
Recent Advances of Optical Imaging in the Second Near‐Infrared Window
Kenry, K., Duan, Y., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201802394 · Cited by 813 · see citing works
Rare-earth-doped biological composites as in vivo shortwave infrared reporters
Naczynski, D. J., Tan, M. C., Zevon, M., Wall, B., Kohl, J., Kulesa, A. B., Chen, S., Roth, C. M., Riman, R. E., & Moghe, P. V. (2013) · Nature Communications · doi:10.1038/ncomms3199 · Cited by 757 · see citing works
Hemmer, E., Benayas, A., Légaré, F., & Vetrone, F. (2016) · Nanoscale Horizons · doi:10.1039/c5nh00073d · Cited by 732 · see citing works
Carr, J. A., Franke, D., Caram, J. R., Perkinson, C. F., Saif, M., Askoxylakis, V., Datta, M., Fukumura, D., Jain, R. K., Bawendi, M. G., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1718917115 · Cited by 721 · see citing works
Next-generation in vivo optical imaging with short-wave infrared quantum dots
Bruns, O. T., Bischof, T. S., Harris, D. K., Franke, D., Shi, Y., Riedemann, L., Bartelt, A., Jaworski, F. B., Carr, J. A., Rowlands, C. J., et al. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-017-0056 · Cited by 686 · see citing works
Li, B., Lu, L., Zhao, M., Lei, Z., & Zhang, F. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201801226 · Cited by 658 · see citing works
A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging
Antaris, A. L., Chen, H., Diao, S., Ma, Z., Zhang, Z., Zhu, S., Wang, J., Lozano, A. X., Fan, Q., Chew, L., et al. (2017) · Nature Communications · doi:10.1038/ncomms15269 · Cited by 623 · see citing works
Self-citationHong, G., Zou, Y., Antaris, A. L., Diao, S., Wu, D., Cheng, K., Zhang, X., Chen, C., Liu, B., He, Y., et al. (2014) · Nature Communications · doi:10.1038/ncomms5206 · Cited by 563 · see citing works
Zhong, Y., Ma, Z., Zhu, S., Yue, J., Zhang, M., Antaris, A. L., Yuan, J., Cui, R., Wan, H., Zhou, Y., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-00917-6 · Cited by 557 · see citing works
Donor Engineering for NIR-II Molecular Fluorophores with Enhanced Fluorescent Performance
Yang, Q., Hu, Z., Zhu, S., Ma, R., Ma, H., Ma, Z., Wan, H., Zhu, T., Jiang, Z., Liu, W., et al. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b10334 · Cited by 554 · see citing works
Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
Ding, F., Zhan, Y., Lu, X., & Sun, Y. (2018) · Chemical Science · doi:10.1039/c8sc01153b · Cited by 540 · see citing works
Self-citationRobinson, J. T., Welsher, K., Tabakman, S. M., Sherlock, S. P., Wang, H., Luong, R. H., & Dai, H. (2010) · Nano Research · doi:10.1007/s12274-010-0045-1 · Cited by 526 · see citing works
Lyu, Y., Fang, Y., Miao, Q., Xu, Z. J., Ding, D., & Pu, K. (2016) · ACS Nano · doi:10.1021/acsnano.6b00168 · Cited by 503 · see citing works
Li, J., Rao, J., & Pu, K. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.025 · Cited by 469 · see citing works
Rational Design of Molecular Fluorophores for Biological Imaging in the NIR‐II Window
Yang, Q., Ma, Z., Wang, H., Zhou, B., Zhu, S., Zhong, Y., Wang, J., Wan, H., Antaris, A., Ma, R., et al. (2017) · Advanced Materials · doi:10.1002/adma.201605497 · Cited by 467 · see citing works
NIR-II nanoprobes in-vivo assembly to improve image-guided surgery for metastatic ovarian cancer
Wang, P., Fan, Y., Lu, L., Liu, L., Fan, L., Zhao, M., Xie, Y., Xu, C., & Zhang, F. (2018) · Nature Communications · doi:10.1038/s41467-018-05113-8 · Cited by 453 · see citing works
Sheng, Z., Guo, B., Hu, D., Xu, S., Wu, W., Liew, W. H., Yao, K., Jiang, J., Liu, C., Zheng, H., et al. (2018) · Advanced Materials · doi:10.1002/adma.201800766 · Cited by 445 · see citing works
Li, C., Zhang, Y., Wang, M., Zhang, Y., Chen, G., Li, L., Wu, D., & Wang, Q. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.010 · Cited by 428 · see citing works
Qi, J., Sun, C., Zebibula, A., Zhang, H., Kwok, R. T. K., Zhao, X., Xi, W., Lam, J. W. Y., Qian, J., & Tang, B. Z. (2018) · Advanced Materials · doi:10.1002/adma.201706856 · Cited by 418 · see citing works
Kobayashi, H., & Choyke, P. L. (2010) · Accounts of Chemical Research · doi:10.1021/ar1000633 · Cited by 417 · see citing works
Tissue-Specific Near-Infrared Fluorescence Imaging
Owens, E. A., Henary, M., Fakhri, G. E., & Choi, H. S. (2016) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00239 · Cited by 416 · see citing works
Flavylium Polymethine Fluorophores for Near‐ and Shortwave Infrared Imaging
Cosco, E. D., Caram, J. R., Bruns, O. T., Franke, D., Day, R. A., Farr, E. P., Bawendi, M. G., & Sletten, E. M. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201706974 · Cited by 415 · see citing works
Robinson, J. T., Hong, G., Liang, Y., Zhang, B., Yaghi, O., & Dai, H. (2012) · Journal of the American Chemical Society · doi:10.1021/ja303737a · Cited by 411 · see citing works
High-efficiency polymer solar cells with small photon energy loss
Kawashima, K., Tamai, Y., Ohkita, H., Osaka, I., & Takimiya, K. (2015) · Nature Communications · doi:10.1038/ncomms10085 · Cited by 391 · see citing works
Traumatic Brain Injury Imaging in the Second Near‐Infrared Window with a Molecular Fluorophore
Zhang, X., Wang, H., Antaris, A. L., Li, L., Diao, S., Ma, R., Nguyen, A., Hong, G., Ma, Z., Wang, J., et al. (2016) · Advanced Materials · doi:10.1002/adma.201600706 · Cited by 386 · see citing works
Wang, R., Li, X., Zhou, L., & Zhang, F. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201407420 · Cited by 365 · see citing works
NIR-I-to-NIR-II fluorescent nanomaterials for biomedical imaging and cancer therapy
Zhao, J., Zhong, D., & Zhou, S. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb02573d · Cited by 354 · see citing works
Photostable Ratiometric Pdot Probe for in Vitro and in Vivo Imaging of Hypochlorous Acid
Wu, L. J., Wu, I., DuFort, C. C., Carlson, M. A., Wu, X., Chen, L., Kuo, C.-T., Qin, Y., Yu, J., Hingorani, S. R., et al. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b01545 · Cited by 350 · see citing works
Zhu, S., Hu, Z., Tian, R., Yung, B. C., Yang, Q., Zhao, S., Kiesewetter, D. O., Niu, G., Sun, H., Antaris, A. L., et al. (2018) · Advanced Materials · doi:10.1002/adma.201802546 · Cited by 349 · see citing works
Liu, L., Wang, S., Zhao, B., Pei, P., Fan, Y., Li, X., & Zhang, F. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201802889 · Cited by 346 · see citing works
Tao, Z., Hong, G., Shinji, C., Chen, C., Diao, S., Antaris, A. L., Zhang, B., Zou, Y., & Dai, H. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201307346 · Cited by 330 · see citing works
Unveiling in Vivo Subcutaneous Thermal Dynamics by Infrared Luminescent Nanothermometers
Ximendes, E. C., Santos, W. Q., Rocha, U., Kagola, U. K., Sanz-Rodrı́guez, F., Fernández, N., Gouveia-Neto, A. D. S., Bravo, D., Domingo, A. M., del Rosal, B., et al. (2016) · Nano Letters · doi:10.1021/acs.nanolett.5b04611 · Cited by 326 · see citing works
Dong, B., Li, C., Chen, G., Zhang, Y., Zhang, Y., Deng, M., & Wang, Q. (2013) · Chemistry of Materials · doi:10.1021/cm400812v · Cited by 300 · see citing works
Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II imaging of cancer
Sun, Y., Qu, C., Chen, H., He, M., Tang, C. C., Shou, K., Hong, S., Yang, M., Jiang, Y., Ding, B., et al. (2016) · Chemical Science · doi:10.1039/c6sc01561a · Cited by 294 · see citing works
Luo, Z., Bin, H., Liu, T., Zhang, Z., Yang, Y., Zhong, C., Qiu, B., Li, G., Gao, W., Xie, D., et al. (2018) · Advanced Materials · doi:10.1002/adma.201706124 · Cited by 285 · see citing works
Self-citationZhu, S., Yang, Q., Antaris, A. L., Yue, J., Ma, Z., Wang, H., Huang, W., Wan, H., Wang, J., Diao, S., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1617990114 · Cited by 281 · see citing works
Self-citationYi, H., Ghosh, D., Ham, M., Qi, J., Barone, P. W., Strano, M. S., & Belcher, A. M. (2012) · Nano Letters · doi:10.1021/nl2031663 · Cited by 276 · see citing works
Miao, Q., Lyu, Y., Ding, D., & Pu, K. (2016) · Advanced Materials · doi:10.1002/adma.201505681 · Cited by 271 · see citing works
Gao, J., Li, J., Geng, W., Chen, F., Duan, X., Zheng, Z., Ding, D., & Guo, D. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.8b02331 · Cited by 266 · see citing works
Sun, Y., Ding, M., Zeng, X., Xiao, Y., Wu, H., Zhou, H., Ding, B., Qu, C., Hou, W., Aga, E.-B., et al. (2017) · Chemical Science · doi:10.1039/c7sc00251c · Cited by 265 · see citing works
Lyu, Y., & Pu, K. (2017) · Advanced Science · doi:10.1002/advs.201600481 · Cited by 246 · see citing works
Wang, R., Zhou, L., Wang, W.-X., Li, X.-M., & Zhang, F. (2017) · Nature Communications · doi:10.1038/ncomms14702 · Cited by 240 · see citing works
Tao, Z., Hong, G., Shinji, C., Chen, C., Diao, S., Antaris, A. L., Zhang, B., Zou, Y., & Dai, H. (2013) · Angewandte Chemie · doi:10.1002/ange.201307346 · Cited by 239 · see citing works
Degradable Semiconducting Oligomer Amphiphile for Ratiometric Photoacoustic Imaging of Hypochlorite
Yin, C., Xu, Z. J., Fan, Q., Huang, W., & Pu, K. (2017) · ACS Nano · doi:10.1021/acsnano.7b01092 · Cited by 227 · see citing works
Self-citationIndocyanine green fluorescence in second near-infrared (NIR-II) window
Starosolski, Z. A., Bhavane, R. C., Ghaghada, K. B., Vasudevan, S. A., Kaay, A., & Annapragada, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187563 · Cited by 220 · see citing works
Ultrastable and Biocompatible NIR‐II Quantum Dots for Functional Bioimaging
Zebibula, A., Alifu, N., Xia, L., Sun, C., Yu, X., Xue, D., Liu, L., Li, G., & Qian, J. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201703451 · Cited by 215 · see citing works
3D NIR‐II Molecular Imaging Distinguishes Targeted Organs with High‐Performance NIR‐II Bioconjugates
Zhu, S., Herraiz, S., Yue, J., Zhang, M., Wan, H., Yang, Q., Ma, Z., Wang, Y., He, J. H., Antaris, A. L., et al. (2018) · Advanced Materials · doi:10.1002/adma.201705799 · Cited by 215 · see citing works
In Vivo Subcutaneous Thermal Video Recording by Supersensitive Infrared Nanothermometers
Ximendes, E. C., Rocha, U., Sales, T. O., Fernández, N., Sanz-Rodrı́guez, F., Martin, I. R., Jacinto, C., & Jaque, D. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201702249 · Cited by 210 · see citing works
Tang, Y., Li, Y., Hu, X., Zhao, H., Ji, Y., Chen, L., Hu, W., Zhang, W., Li, X., Lü, X., et al. (2018) · Advanced Materials · doi:10.1002/adma.201801140 · Cited by 204 · see citing works
Self-citationNavarro‐Cerón, E., Ortgies, D. H., del Rosal, B., Ren, F., Benayas, A., Vetrone, F., Ma, D., Sanz-Rodrı́guez, F., García‐Solé, J., Jaque, D., et al. (2015) · Advanced Materials · doi:10.1002/adma.201501014 · Cited by 200 · see citing works
Shou, K., Tang, Y., Chen, H., Chen, S., Zhang, L., Zhang, A., Fan, Q., Yu, A., & Cheng, Z. (2018) · Chemical Science · doi:10.1039/c8sc00206a · Cited by 199 · see citing works
Self-citationLei, X., Li, R., Tu, D., Shang, X., Liu, Y., You, W., Sun, C., Zhang, F., & Chen, X. (2018) · Chemical Science · doi:10.1039/c8sc00927a · Cited by 177 · see citing works
Huang, Y. X., Zhang, P., Gao, M., Zeng, F., Qin, A., Wu, S., & Tang, B. Z. (2016) · Chemical Communications · doi:10.1039/c6cc03415b · Cited by 156 · see citing works
Ag/Ag2S Nanocrystals for High Sensitivity Near‐Infrared Luminescence Nanothermometry
Ruiz, D., del Rosal, B., Acebrón, M., Palencia, C., Sun, C., Cabanillas‐González, J., López‐Haro, M., Hungría, A. B., Jaque, D., & Juárez, B. H. (2016) · Advanced Functional Materials · doi:10.1002/adfm.201604629 · Cited by 153 · see citing works
Xiao, H., Li, J., Zhao, J., Yin, G., Quan, Y., Wang, J., & Wang, R. (2015) · Journal of Materials Chemistry B · doi:10.1039/c4tb02003k · Cited by 151 · see citing works
Kamimura, M., Matsumoto, T., Suyari, S., Umezawa, M., & Soga, K. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb00070g · Cited by 151 · see citing works
Ma, Z., Zhang, M., Yue, J., Alcazar, C. A., Zhong, Y., Doyle, T. C., Dai, H., & Huang, N. F. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201803417 · Cited by 134 · see citing works
In Vivo Fluorescence Imaging with Ag2S Quantum Dots in the Second Near‐Infrared Region
Hong, G., Robinson, J. T., Zhang, Y., Diao, S., Antaris, A. L., Wang, Q., & Dai, H. (2012) · Angewandte Chemie · doi:10.1002/ange.201206059 · Cited by 128 · see citing works
Benayas, A., Ren, F., Carrasco, E., Marzal, V., del Rosal, B., Gonfa, B. A., Juarranz, Á., Sanz-Rodrı́guez, F., Jaque, D., García‐Solé, J., et al. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201502632 · Cited by 127 · see citing works
Feng, Y., Zhu, S., Antaris, A. L., Chen, H., Xiao, Y., Lu, X., Jiang, L., Diao, S., Yu, K., Wang, Y., et al. (2017) · Chemical Science · doi:10.1039/c6sc04897h · Cited by 113 · see citing works
Self-citationIn Vivo Early Tumor Detection and Diagnosis by Infrared Luminescence Transient Nanothermometry
Santos, H. D. A., Ximendes, E. C., la Cruz, M. D. C. I., Chaves‐Coira, I., del Rosal, B., Jacinto, C., Monge, L., Rubia‐Rodríguez, I., Ortega, D., Mateos, S., et al. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201803924 · Cited by 111 · see citing works
Cancer-Microenvironment-Sensitive Activatable Quantum Dot Probe in the Second Near-Infrared Window
Jeong, S., Song, J., Lee, W., Ryu, Y. M., Jung, Y., Kim, S., Kim, K., Hong, S. C., Myung, S. J., & Kim, S. (2017) · Nano Letters · doi:10.1021/acs.nanolett.6b04261 · Cited by 110 · see citing works
In Vivo Contactless Brain Nanothermometry
del Rosal, B., Ruiz, D., Chaves‐Coira, I., Juárez, B. H., Monge, L., Hong, G., Fernández, N., & Jaque, D. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201806088 · Cited by 99 · see citing works
Recent developments of low-toxicity NIR II quantum dots for sensing and bioimaging
Xu, S., Cui, J., & Wang, L. (2015) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2015.07.017 · Cited by 92 · see citing works
In Vivo Ischemia Detection by Luminescent Nanothermometers
Ximendes, E. C., Rocha, U., del Rosal, B., Vaquero, A. S. G., Sanz-Rodrı́guez, F., Monge, L., Ren, F., Vetrone, F., Ma, D., García‐Solé, J., et al. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201601195 · Cited by 88 · see citing works
del Rosal, B., Jia, B., & Jaque, D. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201803733 · Cited by 67 · see citing works
Cai, L., Deng, L., Huang, X., & Ren, J. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.8b01188 · Cited by 45 · see citing works
Semiconducting Polymer Nanobiocatalysts for Photoactivation of Intracellular Redox Reactions
Lyu, Y., Tian, J., Li, J., Chen, P., & Pu, K. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201806973 · Cited by 42 · see citing works
Xu, X., & Qian, Y. (2017) · New Journal of Chemistry · doi:10.1039/c7nj01970j · Cited by 37 · see citing works
Hu, J., Ortgies, D. H., Aguilar, R., Fernández, N., Porto, L. L., Rodríguez, E. M., García‐Solé, J., Jaque, D., Alfonso, F., & Rivero, F. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201703276 · Cited by 36 · see citing works
Tsuboi, S., Yamada, S., Nakane, Y., Sakata, T., Yasuda, H., & Jin, T. (2017) · ECS Journal of Solid State Science and Technology · doi:10.1149/2.0141801jss · Cited by 23 · see citing works
Zhang, X., Yan, Y., Peng, Q., Wang, J., Hang, Y., & Hua, J. (2017) · Materials Chemistry Frontiers · doi:10.1039/c7qm00298j · Cited by 20 · see citing works
Double-mode detection of HClO by naked eye and concurrent fluorescence increasing in absolute PBS
Wang, B., Wen, J., Gao, K., Yan, H., Xu, Y., Li, H., Chen, M., Wang, W., & Sun, S. (2016) · RSC Advances · doi:10.1039/c6ra03959f · Cited by 4 · see citing works
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Li, C., Chen, G., Zhang, Y., Wu, F., & Wang, Q. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c07022 · Cited by 1,037 · see citing works
Molecular Engineering of NIR‐II Fluorophores for Improved Biomedical Detection
Lei, Z., & Zhang, F. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202007040 · Cited by 689 · see citing works
Li, X., Liu, L., Li, S., Wan, Y., Chen, J., Tian, S., Huang, Z., Xiao, Y., Cui, X., Xiang, C., et al. (2019) · ACS Nano · doi:10.1021/acsnano.9b05383 · Cited by 264 · see citing works
Zhang, Z., Fang, X., Liu, Z., Liu, H., Chen, D., He, S., Zheng, J., Yang, B., Qin, W., Zhang, X., et al. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201914397 · Cited by 242 · see citing works
Review on new horizons of aggregation induced emission: from design to development
Suman, G. R., Pandey, M., & Chakravarthy, A. S. J. (2020) · Materials Chemistry Frontiers · doi:10.1039/d0qm00825g · Cited by 223 · see citing works
Chen, C., Tian, R., Zeng, Y., Chu, C., & Liu, G. (2020) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.9b00734 · Cited by 214 · see citing works
Recent advances in the development of NIR-II organic emitters for biomedicine
Li, J., Liu, Y., Xu, Y., Li, L., Sun, Y., & Huang, W. (2020) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2020.213318 · Cited by 174 · see citing works
Self-citationRecent Advances on Activatable NIR‐II Fluorescence Probes for Biomedical Imaging
Tang, Y., Pei, F., Lü, X., Fan, Q., & Huang, W. (2019) · Advanced Optical Materials · doi:10.1002/adom.201900917 · Cited by 167 · see citing works
Self-citationLi, C., Jiang, G., Yu, J., Ji, W., Liu, L., Zhang, P., Du, J., Zhan, C., Wang, J., & Tang, B. Z. (2022) · Advanced Materials · doi:10.1002/adma.202208229 · Cited by 167 · see citing works
Wang, J., Liu, Y., Morsch, M., Lu, Y., Shangguan, P., Han, L., Wang, Z., Chen, X., Song, C., Liu, S., et al. (2022) · Advanced Materials · doi:10.1002/adma.202106082 · Cited by 163 · see citing works
Near-infrared-II activated inorganic photothermal nanomedicines
Yu, Z., Chan, W. K., Zhang, Y., & Tan, T. T. Y. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120459 · Cited by 160 · see citing works
Zhang, R., Xu, Y., Zhang, Y., Kim, H. S., Sharma, A. K., Gao, J., Yang, G., Kim, J. S., & Sun, Y. (2019) · Chemical Science · doi:10.1039/c9sc03504d · Cited by 159 · see citing works
Ding, F., Fan, Y., Sun, Y., & Zhang, F. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900260 · Cited by 157 · see citing works
Stable, Bright, and Long-Fluorescence-Lifetime Dyes for Deep-Near-Infrared Bioimaging
Li, J., Dong, Y., Wei, R., Jiang, G., Yao, C., Lv, M., Wu, Y., Gardner, S. H., Zhang, F., Lucero, M. Y., et al. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c05826 · Cited by 157 · see citing works
Ling, S., Yang, X., Li, C., Zhang, Y., Yang, H., Chen, G., & Wang, Q. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202000947 · Cited by 156 · see citing works
Recent Advances in Nanomicelles Delivery Systems.
Tawfik, S. M., Azizov, S., Elmasry, M. R., Sharipov, M., & Lee, Y.-I. (2020) · Nanomaterials · doi:10.3390/nano11010070 · Cited by 156 · see citing works
“Fan’s group described a new method to construct a smart NIR-II probe using the bioerasable intermolecular donor–acceptor interaction [196].”
MethodSinglet Oxygen “Afterglow” Therapy with NIR‐II Fluorescent Molecules
Zou, J., Li, L., Zhu, J., Li, X., Yang, Z., Huang, W., & Chen, X. (2021) · Advanced Materials · doi:10.1002/adma.202103627 · Cited by 155 · see citing works
Self-citationActivatable NIR-II organic fluorescent probes for bioimaging
Zhang, X., Li, S., Ma, H., Wang, H., Zhang, X., & Zhang, X. (2022) · Theranostics · doi:10.7150/thno.71359 · Cited by 138 · see citing works
Lighting Up NIR-II Fluorescence in Vivo: An Activable Probe for Noninvasive Hydroxyl Radical Imaging
Feng, W., Zhang, Y., Li, Z., Zhai, S., Lv, W., & Liu, Z. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b04002 · Cited by 134 · see citing works
Hu, X., Tang, Y., Hu, Y., Lu, F., Lü, X., Wang, Y., Li, J., Li, Y., Ji, Y., Wang, W., et al. (2019) · Theranostics · doi:10.7150/thno.34390 · Cited by 132 · see citing works
Self-citationLiu, P., Mu, X., Zhang, X., & Ming, D. (2019) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.9b00610 · Cited by 123 · see citing works
Ma, D., Bian, H., Gu, M., Wang, L., Chen, X., & Peng, X. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.215677 · Cited by 124 · see citing works
Recent Advances in Polymeric Nanoparticles for Enhanced Fluorescence and Photoacoustic Imaging
Ong, S. Y., Zhang, C., Dong, X., & Yao, S. Q. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202101964 · Cited by 120 · see citing works
Li, X., Fang, F., Sun, B., Yin, C., Tan, J., Wan, Y., Zhang, J., Sun, P., Fan, Q., Wang, P., et al. (2020) · Nanoscale Horizons · doi:10.1039/d0nh00672f · Cited by 120 · see citing works
Self-citationAn Activatable NIR‐II Fluorescent Reporter for In Vivo Imaging of Amyloid‐β Plaques
Miao, J., Miao, M., Jiang, Y., Zhao, M., Li, Q., Zhang, Y., An, Y., Pu, K., & Miao, Q. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202216351 · Cited by 118 · see citing works
A short review on NIR-II organic small molecule dyes
Li, L., Dong, X., Li, J., & Wei, J. (2020) · Dyes and Pigments · doi:10.1016/j.dyepig.2020.108756 · Cited by 113 · see citing works
Ding, F., Feng, J. C., Zhang, X., Sun, J., Fan, C., & Ge, Z. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.03.008 · Cited by 100 · see citing works
Single Wavelength Laser Excitation Ratiometric NIR-II Fluorescent Probe for Molecule Imaging in Vivo
Ge, X., Lou, Y., Su, L., Chen, B., Guo, Z., Gao, S. Q., Zhang, W., Chen, T., Song, J., & Yang, H. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c00556 · Cited by 94 · see citing works
Xu, Y., Li, C., Xu, R., Zhang, N., Wang, Z., Jing, X., Yang, Z., Dang, D., Zhang, P., & Meng, L. (2020) · Chemical Science · doi:10.1039/d0sc03160g · Cited by 93 · see citing works
Tumor microenvironment-activated NIR-II reagents for tumor imaging and therapy
Zhang, X., An, L., Tian, Q., Lin, J., & Yang, S. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb00030b · Cited by 83 · see citing works
Zhao, D., Li, C.-Q., Hou, X. L., Xie, X., Zhang, B., Wu, G., Jin, F., Zhao, Y., & Liu, B. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c12611 · Cited by 80 · see citing works
Hu, X., Fang, Z.-T., Zhu, C., Yang, Y., Yáng, Z., & Huang, W. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202401325 · Cited by 77 · see citing works
Self-citationHighly stable and bright AIE dots for NIR-II deciphering of living rats
Qi, J., Alifu, N., Zebibula, A., Wei, P., Lam, J. W. Y., Peng, H., Kwok, R. T. K., Qian, J., & Tang, B. Z. (2020) · Nano Today · doi:10.1016/j.nantod.2020.100893 · Cited by 72 · see citing works
Lü, B., Huang, Y., Zhang, Z., Quan, H., & Yao, Y. S. (2022) · Materials Chemistry Frontiers · doi:10.1039/d2qm00752e · Cited by 62 · see citing works
Molecular Engineering of NIR‐II Fluorophores for Improved Biomedical Detection
Lei, Z., & Zhang, F. (2020) · Angewandte Chemie · doi:10.1002/ange.202007040 · Cited by 63 · see citing works
Degradable π-Conjugated Polymers
Uva, A., Michailovich, S., Hsu, N. S. Y., & Tran, H. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.4c03194 · Cited by 60 · see citing works
Li, S., Chen, H., Liu, H., Liu, L., Yuan, Y., Mao, C., Zhang, W., Zhang, X., Guo, W., Lee, C.-S., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c05885 · Cited by 60 · see citing works
Lai, Y., Dang, Y., Li, F., Ding, C., Yu, H., Zhang, W., & Xu, Z. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202200016 · Cited by 57 · see citing works
Stimuli‐responsive linkers and their application in molecular imaging
Wang, J., Liu, M., Zhang, X., Wang, X., Xiong, M., & Luo, D. (2024) · Exploration · doi:10.1002/exp.20230027 · Cited by 52 · see citing works
Halogen bonding regulated functional nanomaterials
Zheng, J., Suwardi, A., Wong, C. J. E., Loh, X. J., & Li, Z. (2021) · Nanoscale Advances · doi:10.1039/d1na00485a · Cited by 51 · see citing works
Yin, C., Zhang, H., Sun, B., Chen, S., Jiang, X., Miao, X., Sun, P., Hu, W., Fan, Q., & Huang, W. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202106575 · Cited by 48 · see citing works
Self-citationWang, Z., Wang, C., Gan, Q., Cao, Y., Yuan, H., & Hua, D. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b11237 · Cited by 47 · see citing works
NIR-II Fluorescence Imaging for In Vivo Quantitative Analysis
Chen, H.-J., Wang, L., Zhu, H., Wang, Z., & Liu, S. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c04913 · Cited by 44 · see citing works
HClO‐Activated Near‐Infrared Chemiluminescent Probes with a Malononitrile Group for In‐Vivo Imaging
Cao, Y., Gu, J., Chen, Z., Gao, J., Yang, J., Wu, W., Fang, M., Li, Q., Liu, B., & Li, Z. (2024) · Advanced Materials · doi:10.1002/adma.202408941 · Cited by 43 · see citing works
Design strategies and applications of smart optical probes in the second near-infrared window
Chang, B., Chen, J., Bao, J., Dong, K., Chen, S., & Cheng, Z. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114637 · Cited by 43 · see citing works
Wang, M., Bai, S., & Zhang, Y. (2025) · Chemical Society Reviews · doi:10.1039/d5cs00502g · Cited by 41 · see citing works
Zhang, Z., Fang, X., Liu, Z., Liu, H., Chen, D., He, S., Zheng, J., Yang, B., Qin, W., Zhang, X., et al. (2019) · Angewandte Chemie · doi:10.1002/ange.201914397 · Cited by 40 · see citing works
Zhu, Y., Lai, H., Gu, Y., Wei, Z., Chen, L., Lai, X., Han, L., Tan, P., Pu, M., Xiao, F., et al. (2024) · Advanced Science · doi:10.1002/advs.202307569 · Cited by 36 · see citing works
Self-Illuminating Agents for Deep-Tissue Optical Imaging
Li, Q., Zeng, J., Miao, Q., & Gao, M. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00326 · Cited by 36 · see citing works
Conjugated Polymer Nanoparticles for Tumor Theranostics
Li, T., Wu, M., Wei, Q., Xu, D., He, X., Wang, J., Wu, J., & Chen, L. (2023) · Biomacromolecules · doi:10.1021/acs.biomac.2c01446 · Cited by 35 · see citing works
Zheng, Z., Chen, X., Ma, Y., Dai, R., Wu, S., Wang, T., Xing, J. W., Gao, J., & Zhang, R. (2022) · Small · doi:10.1002/smll.202203531 · Cited by 33 · see citing works
Recent advances in synthesis and application of organic near-infrared fluorescence polymers
Zou, W., Zhu, Y., Gu, C., Miao, Y., Wang, S., Yu, B., Shen, Y., & Cong, H. (2020) · Journal of Materials Science · doi:10.1007/s10853-020-04800-6 · Cited by 32 · see citing works
Cui, C., Wang, C., Fu, Q., Song, J., Zou, J., Li, L., Zhu, J., Huang, W., Li, L., Yáng, Z., et al. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.11.023 · Cited by 31 · see citing works
Self-citationRecent Advances of Organic Near-Infrared II Fluorophores in Optical Properties and Imaging Functions
Yu, H., & Ji, M. (2020) · Molecular Imaging and Biology · doi:10.1007/s11307-020-01545-1 · Cited by 30 · see citing works
A design strategy for D–A conjugated polymers for NIR-II fluorescence imaging
Su, Y., Miao, Y., Zhu, Y., Zou, W., Yu, B., Shen, Y., & Cong, H. (2021) · Polymer Chemistry · doi:10.1039/d1py00470k · Cited by 30 · see citing works
Activatable Second Near-Infrared Fluorescent Probes: A New Accurate Diagnosis Strategy for Diseases
Li, D., Pan, J., Xu, S., Fu, S., Chu, C., & Liu, G. (2021) · Biosensors · doi:10.3390/bios11110436 · Cited by 30 · see citing works
Rajapakse, R. M. G., Watkins, D. L., Ranathunge, T. A., Malikaramage, A. U., Gunarathna, H. M. N. P., Sandakelum, L., Wylie, S., Abewardana, P. G. P. R., Egodawele, M. G. S. A. M. E. W. D. D. K., Herath, W. H. M. R. N. K., et al. (2022) · RSC Advances · doi:10.1039/d2ra01176j · Cited by 30 · see citing works
Li, X., Chen, H., Su, Z., Zhao, Q., Wang, Y., Li, N., & Li, S. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c00137 · Cited by 28 · see citing works
Gu, X., Shen, J., Xu, Z., Wang, W., Wu, Y., Zhou, W. J., Xie, C., & Fan, Q. (2024) · Nano Research · doi:10.1007/s12274-024-6434-7 · Cited by 27 · see citing works
Self-citationZhou, W. J., He, X., Wang, J., He, S., Xie, C., Fan, Q., & Pu, K. (2022) · Biomacromolecules · doi:10.1021/acs.biomac.2c00065 · Cited by 26 · see citing works
Self-citationRecent advances in activatable NIR-II organic fluorophores for biomedical applications
Xu, Y., Zhang, P., Gao, A., Xu, R., Wang, Z., Shen, Q., Zhao, Z., Meng, L., & Dang, D. (2022) · Materials Chemistry Frontiers · doi:10.1039/d2qm01120d · Cited by 26 · see citing works
Yan, F., Sun, X., Jiang, Y., Wang, R., Zhang, Y., & Cui, Y. (2020) · Dyes and Pigments · doi:10.1016/j.dyepig.2020.108531 · Cited by 26 · see citing works
Hu, X., Mi, J., Qin, A., Zhu, C., Chen, Z., Yáng, Z., & Huang, W. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216992 · Cited by 26 · see citing works
Self-citationAn aza-BODIPY-based NIR-II luminogen enables efficient phototheranostics
Yang, N., Song, S., Liu, C., Ren, J., Wang, X., Zhu, S., & Yu, C. (2022) · Biomaterials Science · doi:10.1039/d2bm00670g · Cited by 24 · see citing works
Hu, X., Chen, Z., Ao, H., Fan, Q., Yáng, Z., & Huang, W. (2022) · Advanced Optical Materials · doi:10.1002/adom.202201067 · Cited by 23 · see citing works
Self-citationMen, X., & Yuan, Z. (2020) · ACS Applied Polymer Materials · doi:10.1021/acsapm.0c00715 · Cited by 23 · see citing works
Chen, T., Su, L., Lin, L., Ge, X., Bai, F., Niu, M., Wang, C., Song, J., Guo, S., & Yang, H. (2022) · Nano Research · doi:10.1007/s12274-021-3997-4 · Cited by 22 · see citing works
Rational Modulation Strategies to Improve Bioimaging Applications for Organic NIR‐II Fluorophores
Wang, Z., She, M., Chen, J., Cheng, Z.-Q., & Li, J. (2021) · Advanced Optical Materials · doi:10.1002/adom.202101634 · Cited by 22 · see citing works
Wei, Q., Xu, D., Li, T., He, X., Wang, J., Zhao, Y., & Chen, L. (2022) · Biosensors · doi:10.3390/bios12121126 · Cited by 19 · see citing works
Ma, K. L., Jiang, Q., Yang, Y., & Zhang, F. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb01957a · Cited by 18 · see citing works
Chi, Y., Hu, Q., Yi, S., Qu, H., & Xiao, Y. C. (2023) · Talanta · doi:10.1016/j.talanta.2023.124668 · Cited by 17 · see citing works
Sun, C., Wang, B., Dong, B., Du, W., Zhou, G., Yan, H., Wei, H., Li, W., Chen, S., Wang, H., et al. (2021) · ECS Journal of Solid State Science and Technology · doi:10.1149/2162-8777/ac0f11 · Cited by 17 · see citing works
Hu, X., Sun, F., Zhu, C., Yáng, Z., & Huang, W. (2022) · Nano Research · doi:10.1007/s12274-022-5145-1 · Cited by 17 · see citing works
Self-citationZhang, J., Luo, Z., Wang, W., Yang, Y., Li, D., & Ma, Y. (2019) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2019.04.013 · Cited by 16 · see citing works
Zhang, W., Song, Q., Qin, H. Y., Jia, H., Shang, Z., Zhang, Z., & Meng, Q. (2025) · Analytical Methods · doi:10.1039/d4ay02192d · Cited by 15 · see citing works
Cao, Y., Yang, J., Liu, B., & Li, Z. (2025) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.5c00043 · Cited by 15 · see citing works
Ling, S., Yang, X., Li, C., Zhang, Y., Yang, H., Chen, G., & Wang, Q. (2020) · Angewandte Chemie · doi:10.1002/ange.202000947 · Cited by 15 · see citing works
Wu, M., Gong, D., Zhou, Y., Zha, Z., & Xia, X. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb01590d · Cited by 14 · see citing works
Yang, L., Gao, Y., Wei, J., Cheng, Z., Wu, S., Zou, L., Li, S., & Li, P. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02080-1 · Cited by 13 · see citing works
Jiahui, 刘. L., Yanqing, 杨. Y., Rui, 马. M., & Kebin, 施. S. (2023) · Chinese Journal of Lasers · doi:10.3788/cjl230819 · Cited by 12 · see citing works
Nie, K., Yuan, Y., Peng, X., Song, J., & Qu, J. (2019) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2019.127632 · Cited by 11 · see citing works
Chen, Y., Liu, Y., Kuang, P., Guo, C., Zan, J., Xie, C., Yin, C., & Fan, Q. (2022) · Chemical Communications · doi:10.1039/d1cc07195e · Cited by 10 · see citing works
Self-citationLiu, Y., Lü, X., Zhou, W. J., & Fan, Q. (2023) · New Journal of Chemistry · doi:10.1039/d3nj03868h · Cited by 10 · see citing works
Self-citationZhang, L., Xiao, Y., Mao, W., Huang, J., Huang, H., Yang, R., Zhang, Y., He, X., & Wang, K. (2022) · Chemical Communications · doi:10.1039/d1cc06606d · Cited by 6 · see citing works
An Activatable NIR‐II Fluorescent Reporter for In Vivo Imaging of Amyloid‐β Plaques
Miao, J., Miao, M., Jiang, Y., Zhao, M., Li, Q., Zhang, Y., An, Y., Pu, K., & Miao, Q. (2022) · Angewandte Chemie · doi:10.1002/ange.202216351 · Cited by 5 · see citing works
Designing small organic molecular NIR-II fluorophores by ring strain modulation
Wang, X., Li, T., Yang, X., Yang, X.-Y., Ma, Z., Wu, X., Zhang, Y., Chen, G., Jiang, J., & Li, C. (2025) · Chemical Communications · doi:10.1039/d5cc00515a · Cited by 3 · see citing works
Polymer nanomaterials in bioimaging
Ghamsari, M. S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814657-6.00011-2 · Cited by 2 · see citing works
Recent Advances in Polymeric Nanoparticles for Enhanced Fluorescence and Photoacoustic Imaging
Ong, S. Y., Zhang, C., Dong, X., & Yao, S. Q. (2021) · Angewandte Chemie · doi:10.1002/ange.202101964 · Cited by 2 · see citing works
Luo, G., Ma, F., Yang, Y., Yang, C., Li, X., Xie, J., Xiong, K., Chen, P., Ma, K., Zhao, Z., et al. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-026-02699-0 · Cited by 1 · see citing works
Near-Infrared II Optical Imaging
He, S., & Cheng, Z. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-816386-3.00025-9 · Cited by 1 · see citing works
Du, M., Liang, T., Gu, X., Liu, Y., Wang, N., Zhou, W. J., Xie, C., & Fan, Q. (2023) · Nanotechnology · doi:10.1088/1361-6528/acf321 · Cited by 1 · see citing works
Self-citationKamimura, M. (2020) · Springer eBooks · doi:10.1007/978-981-15-9627-8_3
Qin, Z., Liu, X., Zhang, H., Wang, S., Wu, X., Pu, X., Ji, Y., Yang, J., Guo, X., Wang, J., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2008687/v1
Isaeva, Y. A., Blagodarnaia, E. D., Vetyugova, A. A., Stepanov, M. E., Poletavkina, L. A., Dyadishchev, I. V., Trul, A. A., Egorova, T. V., Akasov, R., & Luponosov, Y. N. (2025) · Polymers · doi:10.3390/polym17243304
Yang, L., Gao, Y., Wei, J., Cheng, Z., Wu, S., Zou, L., Li, S., & Li, P. (2023) · Figshare · doi:10.6084/m9.figshare.24089294
Advances in polymer-based NIR-II fluorescent probes and their biomedical applications
Ahmad, A., Kanwal, M., Palaniyappan, N., Adnan, M., Fayaz, M., Pan, W., Akram, N., Rafiq, M., Rizwan, M., Yu, B., et al. (2026) · Sustainable materials and technologies · doi:10.1016/j.susmat.2026.e02197
- Authors
- Tang, Y., Li, Y., Lu, X., Hu, X., Zhao, H., Hu, W., Lu, F., Fan, Q., & Huang, W.
- Affiliations
- Nanjing University of Posts and Telecommunications (CN)
- Nanjing Tech University (CN)
- Northwestern Polytechnical University (CN)
- Corresponding author
- Fan, Quli
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2018-12-27
- Volume
- 29
- Issue
- 10
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2907582934
- Cited by
- 96
- References
- 81
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 9 · 2023: 9 · 2022: 20 · 2021: 15 · 2020: 22 · 2019: 13
- FWCI
- 4.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Functional Materials (publishedVersion)
- Funders
- National Natural Science Foundation of China (21674048, 21574064)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Keywords
- NIR-II fluorescence imaging, non-fullerene acceptors, inflammation imaging, amphiphilic polymer coating, single nanoparticles, deep tissue imaging
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