Cited by 392Mindfulness and Compassion InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Research Topics

MINDFULNESS AND EMOTION REGULATION IN DEPRESSION AND ANXIETY: COMMON AND DISTINCT MECHANISMS OF ACTION: Research Article: Mindfulness and Emotion Regulation

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Desrosiers, Alethea, Vine, Vera, Klemanski, David H., Nolen-Hoeksema, Susan·2013·Depression and Anxiety

Abstract

BACKGROUND: The current study seeks to investigate the mechanisms through which mindfulness is related to mental health in a clinical sample of adults by examining (1) whether specific cognitive emotion regulation strategies (rumination, reappraisal, worry, and nonacceptance) mediate associations between mindfulness and depression and anxiety, respectively, and (2) whether these emotion regulation strategies operate uniquely or transdiagnostically in relation to depression and anxiety. METHODS: Participants were 187 adults seeking treatment at a mood and anxiety disorders clinic in Connecticut. Participants completed a battery of self-report measures that included assessments of depression and anxiety (Mood and Anxiety Symptom Questionnaire), and emotion regulation (Ruminative Response Scale, Penn State Worry Questionnaire, Emotion Regulation Questionnaire, Difficulties in Emotion Regulation Scale). RESULTS: Simple mediation analyses indicated that rumination and worry significantly mediated associations between mindfulness and anxiety symptoms, whereas rumination and reappraisal significantly mediated associations between mindfulness and depressive symptoms. Multiple mediation analyses showed that worry significantly mediated associations between mindfulness and anxiety symptoms and rumination and reappraisal significantly mediated associations between mindfulness and depressive symptoms. CONCLUSIONS: Findings suggest that mindfulness operates through distinct and common mechanisms depending on clinical context.

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  • Rumination may be a contributor to anxiety, particularly due to repetitive thoughts about future negative events.

    “Rumination may be a contributor to anxiety, particularly due to repetitive thoughts about future negative events.”

    From Mindfulness in mood and anxiety disorders: A review of the literature (2017) · cites this paper as [3]

    The Discussion distinguishes the two forms of repetitive thinking: worry concerns future negative outcomes, whereas rumination concerns present and past negative events. Although the paper links rumination with anxiety in simple mediation analysis, it does not attribute that link to thoughts about future events; in multiple mediation analysis, worry rather than rumination was the significant mediator for anxiety. (LLM, conf=0.88)

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  • Reappraisal could work specifically with depressive and anxiety symptoms.

    “However, reappraisal could work specifically with depressive and anxiety symptoms.3”

    From Mindfulness in mood and anxiety disorders: A review of the literature (2017) · cites this paper as [3]

    The Depression and Anxiety section reports that reappraisal significantly mediated depressive symptoms but not anxiety symptoms. The Conclusion likewise says reappraisal may operate with specificity to depression, so the claim is supported for depressive symptoms but not for anxiety symptoms. (LLM, conf=0.88)

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  • Cultivating a more accepting and flexible emotion regulation approach may protect against depression and anxiety through reappraisal, acceptance, and problem-solving.

    “The second pathway includes cultivating a more accepting and flexible emotion regulation approach that may protect against depression and anxiety through reappraisal, acceptance, and problem-solving [23, 34, 75–78].”

    From Emotion Regulation as a Mechanism of Mindfulness in Individual Cognitive-Behavioral Therapy for Depression and Anxiety Disorders (2024) · cites this paper as [23]

    The Results report that reappraisal mediated the association between mindfulness and depression symptoms, but not anxiety symptoms; nonacceptance did not significantly mediate either association. The paper discusses accepting emotions, but the passages do not establish problem-solving as a pathway, so it does not support all three proposed mechanisms for both conditions. (LLM, conf=0.86)

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  • These findings emphasize diverse routes through which symptoms are alleviated in individuals with depression and anxiety disorders and contribute to expanding literature that underscores the fundamental role of emotion regulation for mindfulness.

    “These findings emphasize the diverse routes through which symptoms are alleviated in individuals with depression and anxiety disorders and contribute to the expanding literature that underscores the fundamental role of emotion regulation for mindfulness [23, 36, 119].”

    From Emotion Regulation as a Mechanism of Mindfulness in Individual Cognitive-Behavioral Therapy for Depression and Anxiety Disorders (2024) · cites this paper as [23]

    Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.

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  • The finding that individuals reported increases in interoceptive awareness (measured by MAIA) is in line with broader theoretical mindfulness frameworks that suggest MT helps individuals learn to become more aware of and observe unpleasant emotions with awareness imbued with curiosity.

    “These results and the finding that individuals reported increases in interoceptive awareness (measured by the MAIA) are in line with broader theoretical mindfulness frameworks that suggest that MT helps individuals learn to become more aware of and observe unpleasant emotions with awareness imbued with curiosity [72].”

    From Clinical Efficacy and Psychological Mechanisms of an App-Based Digital Therapeutic for Generalized Anxiety Disorder: Randomized Controlled Trial (2021) · cites this paper as [72]

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Research works printed but not linked: 5

  1. [3]3. Carmody J, Baer RA. Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. J Clin Psychol 2008;65:613-626.
  2. [10]10. Hayes SC, McCurry SM, Afari N, Wilson KG. Acceptance and Commitment Therapy: A Manual for the Treatment of Emotional Avoidance. Reno, NV: Context Press; 1993.
  3. [32]32. Nolen-Hoeksema S, Wisco BE, Lyubomirsky S. Rethinking ru- mination. Perspect Psychol Sci 2008;3:400-424.
  4. [49]49. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clin- ical Interview for DSM-IV TR Axis I Disorders, Research Version, Patient Edition. New York: Biometrics Research, New York State Psychiatric Institute; 2002.
  5. [63]63. Borkovec TD, Alcaine OM, Behar E. Avoidance theory of worry and generalized anxiety disorder. In: Heimberg RG, Turk CL, Mennin DS, editors. Generalized Anxiety Disorders: Advances in Research and Practice. New York: Guilford Press; 2004:77-108.

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Authors
Desrosiers, A., Vine, V., Klemanski, D. H., & Nolen-Hoeksema, S.
Affiliations
  • Yale University (US)
  • Department of Psychology; Yale University; New Haven; Connecticut
Corresponding author
Desrosiers, Alethea
Venue
Depression and Anxiety
Published
2013-04-16
Volume
30
Issue
7
Pages
654-661
ISSN
1091-4269 (ISSN-L)
OpenAlex
W1512345889
Cited by
392
References
66
Citations by year
2026: 15 · 2025: 41 · 2024: 30 · 2023: 50 · 2022: 26 · 2021: 37 · 2020: 50 · 2019: 32 · 2018: 28 · 2017: 20 · 2016: 28 · 2015: 18 · 2014: 15 · 2013: 2
FWCI
23.34
Type
journal article
Language
en
Open access
Locations
  • Depression and Anxiety (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Drug Abuse (T32DA019426)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Keywords
mindfulness, emotion regulation, depression, anxiety, rumination, cognitive reappraisal, worry, mediation, transdiagnostic mechanisms, mood and anxiety disorders
MeSH terms
Adolescent, Adult, Aged, Anxiety, Anxiety Disorders, Depression, Emotions, Female, Humans, Male, Middle Aged, Models, Psychological, Surveys and Questionnaires, Mood Disorders, Mindfulness

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