Mechanism of Candida pathogenesis: Revisiting the vital drivers
Abstract
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits, morphological and phenotypic switching, biofilm formation, tissue damaging extracellular hydrolytic enzymes, metabolic flexibility, genome plasticity, adaptation to environmental pH fluctuation, robust nutrient acquisition system, adherence and invasions (mediated by adhesins and invasins), heat shock proteins (HSPs), cytolytic proteins, escape from phagocytosis, evasion from host immune system, synergistic coaggregation with resident microbiota, resistance to antifungal agents, and the ability to efficiently respond to multiple stresses are some of the major pathogenic determinants of Candida species. The existence of multiple connections, in addition to the interactions and associations among all of these factors, are distinctive features that play important roles in the establishment of Candida infections. This review describes all the underlying factors and mechanisms involved in Candida pathogenesis by evaluating pathogenic determinants of Candida species. It reinforces the already available pool of data on the pathogenesis of Candida species by providing a clear and simplified understanding of the most important factors implicated in the pathogenesis of Candida species. The Candida pathogenesis network, an illustration linking all the major determinants of Candida pathogenesis, is also presented. Taken together, they will further improve our current understanding of how these factors modulate virulence and consequent infection(s). Development of new antifungal drugs and better therapeutic approaches to candidiasis can be achieved in the near future with continuing progress in the understanding of the mechanisms of Candida pathogenesis.
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Frequent drug targets are formation of hyphae, aspartyl proteinases, and phospholipase enzymes.
“Indeed, frequent drug targets are the formation of hyphae, which is one of the first steps in biofilm formation, the enzymes aspartyl proteinases, key virulence factors able to degrade many human proteins (i.e., mucin, immune system molecules, endothelial cell proteins, and coagulation factors), and phospholipase enzymes, proteins able to break the ester bonds of phospholipids, inducing cell lysis”
From Antimicrobial Properties of Antidepressants and Antipsychotics—Possibilities and Implications (2021) · cites this paper as [89]
Cites
International Study of the Prevalence and Outcomes of Infection in Intensive Care Units
Vincent, J. (2009) · JAMA · doi:10.1001/jama.2009.1754 · Cited by 3,639 · see citing works
Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision
Bongomin, F., Gago, S., Oladele, R., & Denning, D. (2017) · Journal of Fungi · doi:10.3390/jof3040057 · Cited by 2,953 · see citing works
Antibiotic resistance: a rundown of a global crisis
Aslam, B., Wang, W., Arshad, M. I., Khurshid, M., Muzammil, S., Rasool, M. H., Nisar, M. A., Alvi, R. F., Aslam, M. A., Qamar, M. U., et al. (2018) · Infection and Drug Resistance · doi:10.2147/idr.s173867 · Cited by 2,581 · see citing works
<i>Candida albicans</i> pathogenicity mechanisms
Mayer, F. L., Wilson, D., & Hube, B. (2013) · Virulence · doi:10.4161/viru.22913 · Cited by 1,848 · see citing works
Homeostatic Immunity and the Microbiota
Belkaid, Y., & Harrison, O. J. (2017) · Immunity · doi:10.1016/j.immuni.2017.04.008 · Cited by 1,261 · see citing works
Sardi, J. C. O., Scorzoni, L., Bernardi, T., Fusco-Almeida, A. M., & Mendes Giannini, M. J. S. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.045054-0 · Cited by 1,184 · see citing works
Growth of Candida albicans hyphae
Sudbery, P. E. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2636 · Cited by 1,110 · see citing works
Candidalysin is a fungal peptide toxin critical for mucosal infection
Moyes, D. L., Wilson, D., Richardson, J. P., Mogavero, S., Tang, S. X., Wernecke, J., Hoefs, S., Gratacap, R. L., Robbins, J., Runglall, M., et al. (2016) · Nature · doi:10.1038/nature17625 · Cited by 928 · see citing works
The glyoxylate cycle is required for fungal virulence
Lorenz, M. C., & Fink, G. R. (2001) · Nature · doi:10.1038/35083594 · Cited by 745 · see citing works
Polymicrobial Interactions: Impact on Pathogenesis and Human Disease
Peters, B. M., Jabra‐Rizk, M. A., O’May, G. A., Costerton, J. W., & Shirtliff, M. E. (2012) · Clinical Microbiology Reviews · doi:10.1128/cmr.00013-11 · Cited by 713 · see citing works
A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans
Nobile, C. J., Fox, E. P., Nett, J. E., Sorrells, T. R., Mitrovich, Q. M., Hernday, A. D., Tuch, B. B., Andes, D. R., & Johnson, A. D. (2012) · Cell · doi:10.1016/j.cell.2011.10.048 · Cited by 711 · see citing works
Candida Biofilms: Threats, Challenges, and Promising Strategies
Cavalheiro, M., & Teixeira, M. C. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00028 · Cited by 690 · see citing works
Stoldt, V. R., Sonneborn, A., Leuker, C. E., & Ernst, J. F. (1997) · The EMBO Journal · doi:10.1093/emboj/16.8.1982 · Cited by 595 · see citing works
Flocculation, adhesion and biofilm formation in yeasts
Verstrepen, K. J., & Klis, F. M. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05072.x · Cited by 589 · see citing works
Control of Filament Formation in Candida albicans by the Transcriptional Repressor TUP1
Braun, B. R., & Johnson, A. D. (1997) · Science · doi:10.1126/science.277.5322.105 · Cited by 515 · see citing works
C-type lectins in immunity: recent developments
Dambuza, I. M., & Brown, G. D. (2015) · Current Opinion in Immunology · doi:10.1016/j.coi.2014.12.002 · Cited by 482 · see citing works
Regulation of Cell-Surface Genes and Biofilm Formation by the C. albicans Transcription Factor Bcr1p
Nobile, C. J., & Mitchell, A. P. (2005) · Current Biology · doi:10.1016/j.cub.2005.05.047 · Cited by 464 · see citing works
NRG1 represses yeast–hypha morphogenesis and hypha‐specific gene expression in Candida albicans
Murad, A. M. A., Leng, P., Straffon, M., Wishart, J., Macaskill, S., MacCallum, D., Schnell, N., Talibi, D., Marechal, D., Tekaia, F., et al. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4742 · Cited by 452 · see citing works
Biofilm-Forming Capability of Highly Virulent, Multidrug-Resistant <i>Candida auris</i>
Sherry, L., Ramage, G., Kean, R., Borman, A., Johnson, E. M., Richardson, M. D., & Rautemaa-Richardson, R. (2017) · Emerging Infectious Diseases · doi:10.3201/eid2302.161320 · Cited by 420 · see citing works
Function of <i>Candida albicans</i> Adhesin Hwp1 in Biofilm Formation
Nobile, C. J., Nett, J. E., Andes, D. R., & Mitchell, A. P. (2006) · Eukaryotic Cell · doi:10.1128/ec.00194-06 · Cited by 395 · see citing works
Mucosal damage and neutropenia are required for Candida albicans dissemination
Koh, A. Y., Köhler, J. R., Coggshall, K. T., Van Rooijen, N., & Pier, G. B. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.0040035 · Cited by 360 · see citing works
Santos, G. C. D. O., Vasconcelos, C. C., Lopes, A. J. O., Cartágenes, M. D. S. D. S., Filho, A. K. D. B., do Nascimento, F. R. F., Ramos, R. M., Pires, E. R. R. B., de Andrade, M. S., Rocha, F. M. G., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01351 · Cited by 357 · see citing works
Candida albicans Als3, a multifunctional adhesin and invasin
Liu, Y., & Filler, S. G. (2011) · Eukaryotic Cell · doi:10.1128/ec.00279-10 · Cited by 354 · see citing works
Wisplinghoff, H., Seifert, H., Tallent, S. M., Bischoff, T., Wenzel, R. P., & Edmond, M. B. (2003) · The Pediatric Infectious Disease Journal · doi:10.1097/01.inf.0000078159.53132.40 · Cited by 350 · see citing works
NRG1, a repressor of filamentous growth in C.albicans, is down‐regulated during filament induction
Braun, B. R., Kadosh, D., & Johnson, A. D. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4753 · Cited by 345 · see citing works
Dadar, M., Tiwari, R., Karthik, K., Chakraborty, S., Shahali, Y., & Dhama, K. (2018) · Microbial Pathogenesis · doi:10.1016/j.micpath.2018.02.028 · Cited by 338 · see citing works
Biofilm Matrix Regulation by Candida albicans Zap1
Nobile, C. J., Nett, J. E., Hernday, A. D., Homann, O. R., Deneault, J.-S., Nantel, A., Andes, D. R., Johnson, A. D., & Mitchell, A. P. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000133 · Cited by 337 · see citing works
Commensal Fungi in Health and Disease
Limon, J. J., Skalski, J. H., & Underhill, D. M. (2017) · Cell Host & Microbe · doi:10.1016/j.chom.2017.07.002 · Cited by 336 · see citing works
Adhesins in human fungal pathogens: glue with plenty of stick.
de Groot, P. W. J., Bader, O., de Boer, A. D., Weig, M., & Chauhan, N. (2013) · Eukaryotic Cell · doi:10.1128/ec.00364-12 · Cited by 319 · see citing works
Sonnenborn, U. (2016) · FEMS Microbiology Letters · doi:10.1093/femsle/fnw212 · Cited by 315 · see citing works
Development of Candida-associated denture stomatitis: new insights
Pereira‐Cenci, T., Cury, A. A. D. B., Wim Crielaard, A., & ten Cate, J. M. (2008) · Journal of Applied Oral Science · doi:10.1590/s1678-77572008000200002 · Cited by 308 · see citing works
Candida Species Biofilms’ Antifungal Resistance
Silva, S. M., Rodrigues, C. F., Araújo, D., Rodrigues, M. E., & Henriques, M. (2017) · Journal of Fungi · doi:10.3390/jof3010008 · Cited by 308 · see citing works
Major roles of isocitrate lyase and malate synthase in bacterial and fungal pathogenesis
Dunn, M. F., Ramírez‐Trujillo, J. A., & Hernández-Lucas, I. (2009) · Microbiology · doi:10.1099/mic.0.030858-0 · Cited by 305 · see citing works
Adherence and biofilm formation of non-Candida albicans Candida species
Silva, S., Negri, M., Henriques, M., Oliveira, R., Williams, D. W., & Azeredo, J. (2011) · Trends in Microbiology · doi:10.1016/j.tim.2011.02.003 · Cited by 304 · see citing works
Wisplinghoff, H., Ebbers, J., Geurtz, L., Stefanik, D., Major, Y., Edmond, M. B., Wenzel, R. P., & Seifert, H. (2014) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2013.09.005 · Cited by 293 · see citing works
A Candida Biofilm-Induced Pathway for Matrix Glucan Delivery: Implications for Drug Resistance
Taff, H. T., Nett, J. E., Zarnowski, R., Ross, K. M., Sanchez, H., Cain, M. T., Hamaker, J., Mitchell, A. P., & Andes, D. R. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002848 · Cited by 291 · see citing works
Kadosh, D., & Johnson, A. D. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0073 · Cited by 285 · see citing works
Schlecht, L. M., Peters, B. M., Krom, B. P., Freiberg, J. A., Hänsch, G. M., Filler, S. G., Jabra‐Rizk, M. A., & Shirtliff, M. E. (2014) · Microbiology · doi:10.1099/mic.0.083485-0 · Cited by 282 · see citing works
<i>Candida</i> Species Exhibit Differential In Vitro Hemolytic Activities
Luo, G., Samaranayake, L. P., & Yau, J. Y. Y. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.8.2971-2974.2001 · Cited by 282 · see citing works
Candida albicans interactions with epithelial cells and mucosal immunity
Naglik, J. R., Moyes, D. L., Wächtler, B., & Hube, B. (2011) · Microbes and Infection · doi:10.1016/j.micinf.2011.06.009 · Cited by 277 · see citing works
Wächtler, B., Wilson, D., Haedicke, K., Dalle, F., & Hube, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017046 · Cited by 270 · see citing works
Candida albicans Interactions with Bacteria in the Context of Human Health and Disease
Morales, D. K., & Hogan, D. A. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000886 · Cited by 270 · see citing works
Smith, D. A., Nicholls, S., Morgan, B. A., Brown, A. J. P., & Quinn, J. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-03-0181 · Cited by 263 · see citing works
The MAP kinase signal transduction network in Candida albicans
Alonso‐Monge, R., Román, E., Nombela, C., & Plá, J. (2006) · Microbiology · doi:10.1099/mic.0.28616-0 · Cited by 263 · see citing works
Bailey, D., Feldmann, P. J. F., Bovey, M., Gow, N. A., & Brown, A. J. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.18.5353-5360.1996 · Cited by 259 · see citing works
Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels
Brown, A. J. P., Brown, G. D., Netea, M. G., & Gow, N. A. R. (2014) · Trends in Microbiology · doi:10.1016/j.tim.2014.07.001 · Cited by 258 · see citing works
TUP1, CPH1 and EFG1 Make Independent Contributions to Filamentation in Candida albicans
Braun, B. R., & Johnson, A. D. (2000) · Genetics · doi:10.1093/genetics/155.1.57 · Cited by 257 · see citing works
Role of Heat-Shock Proteins in Cellular Function and in the Biology of Fungi
Tiwari, S., Thakur, R., & Shankar, J. (2015) · Biotechnology Research International · doi:10.1155/2015/132635 · Cited by 255 · see citing works
Transcriptional control of dimorphism in Candida albicans
Liu, H. (2001) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(01)00275-2 · Cited by 244 · see citing works
Banerjee, M., Thompson, D. S., Lazzell, A., Carlisle, P. L., Pierce, C., Monteagudo, C., López-Ribot, J. L., & Kadosh, D. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-11-1110 · Cited by 243 · see citing works
Candida albicans ALS3 and insights into the nature of the ALS gene family
Hoyer, L. L., Payne, T. L., Bell, M., Myers, A. M., & Scherer, S. (1998) · Current Genetics · doi:10.1007/s002940050359 · Cited by 242 · see citing works
Substrate binding site flexibility of the small heat shock protein molecular chaperones
Jaya, N., Garcia, V. G., & Vierling, E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902177106 · Cited by 241 · see citing works
Fungal-Bacterial Interactions in Health and Disease
Krüger, W., Vielreicher, S., Kapitan, M., Jacobsen, I. D., & Niemiec, M. J. (2019) · Pathogens · doi:10.3390/pathogens8020070 · Cited by 228 · see citing works
Host Cell Invasion and Virulence Mediated by Candida albicans Ssa1
Sun, J. N., Solis, N. V., Phan, Q. T., Bajwa, J. S., Kashleva, H., Thompson, A., Liu, Y., Dongari-Bagtzoglou, A., Edgerton, M., & Filler, S. G. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001181 · Cited by 220 · see citing works
Environmental pH modulation by pathogenic fungi as a strategy to conquer the host
Vylkova, S. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006149 · Cited by 212 · see citing works
Naglik, J. R., Rodgers, C. A., Shirlaw, P. J., Dobbie, J. L., Fernandes‐Naglik, L. L., Greenspan, D., Agabian, N., & Challacombe, S. J. (2003) · The Journal of Infectious Diseases · doi:10.1086/376536 · Cited by 206 · see citing works
Verma, A. H., Richardson, J., Zhou, C., Coleman, B. M., Moyes, D., Ho, J., Huppler, A., Ramani, K., McGeachy, M., Mufazalov, I., et al. (2017) · Science immunology · doi:10.1126/sciimmunol.aam8834 · Cited by 203 · see citing works
Sherrington, S. L., Sorsby, E., Mahtey, N., Kumwenda, P., Lenardon, M. D., Brown, I., Ballou, E. R., MacCallum, D. M., & Hall, R. A. (2017) · PLOS Pathogens · doi:10.1371/journal.ppat.1006403 · Cited by 202 · see citing works
Richardson, J. P., Willems, H. M. E., Moyes, D. L., Shoaie, S., Barker, K. S., Tan, S. L., Palmer, G. E., Hube, B., Naglik, J. R., & Peters, B. M. (2017) · Infection and Immunity · doi:10.1128/iai.00645-17 · Cited by 196 · see citing works
Candida albicans hyphal initiation and elongation
Lü, Y., Su, C., & Liu, H. (2014) · Trends in Microbiology · doi:10.1016/j.tim.2014.09.001 · Cited by 195 · see citing works
Oral candidosis – Clinical challenges of a biofilm disease
Rautemaa‐Richardson, R., & Ramage, G. (2011) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2011.585606 · Cited by 187 · see citing works
The Ras/cAMP/PKA signaling pathway and virulence in <i>Candida albicans</i>
Hogan, D. A., & Sundstrom, P. (2009) · Future Microbiology · doi:10.2217/fmb.09.106 · Cited by 186 · see citing works
Virulence factors of Candida species.
Ruechel, R., Samaranayake, L. P., & MacFarlane, T. W. (1990) · Cited by 185 · see citing works
Hyphal Growth in Human Fungal Pathogens and Its Role in Virulence
Brand, A. (2011) · International Journal of Microbiology · doi:10.1155/2012/517529 · Cited by 180 · see citing works
How human pathogenic fungi sense and adapt to pH: the link to virulence
Davis, D. A. (2009) · Current Opinion in Microbiology · doi:10.1016/j.mib.2009.05.006 · Cited by 177 · see citing works
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
Ho, J., Yang, X., Nikou, S.-A., Kichik, N., Donkin, A., Ponde, N., Richardson, J., Gratacap, R. L., Archambault, L., Zwirner, C. P., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09915-2 · Cited by 176 · see citing works
Targeting<i>Candida albicans</i>filamentation for antifungal drug development
Vila, T., Romo, J. A., Pierce, C. G., McHardy, S. F., Saville, S. P., & Lopez-Ribot, J. L. (2017) · Virulence · doi:10.1080/21505594.2016.1197444 · Cited by 174 · see citing works
Tsang, C., Chu, F., Leung, W. K., Jin, L., Samaranayake, L., & Siu, S.-C. (2007) · Journal of Medical Microbiology · doi:10.1099/jmm.0.47303-0 · Cited by 173 · see citing works
The metabolic basis of Candida albicans morphogenesis and quorum sensing.
Han, T.-L., Cannon, R. D., & Villas-Bôas, S. G. (2011) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2011.04.002 · Cited by 173 · see citing works
Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface
Moyes, D., Richardson, J., & Naglik, J. (2015) · Virulence · doi:10.1080/21505594.2015.1012981 · Cited by 171 · see citing works
Cell biology of Candida albicans–host interactions
Dantas, A. D. S., Lee, K. K., Raziunaite, I., Schaefer, K., Wagener, J., Yadav, B., & Gow, N. A. R. (2016) · Current Opinion in Microbiology · doi:10.1016/j.mib.2016.08.006 · Cited by 170 · see citing works
Lü, Y., Su, C., Wang, A., & Liu, H. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001105 · Cited by 163 · see citing works
Li, T., Du, H., Guan, G., Dai, Y., Nobile, C. J., Liang, W., Cao, C., Zhang, Q., Zhong, J., & Huang, G. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001830 · Cited by 159 · see citing works
Comprehensive Analysis of Glycosylphosphatidylinositol-Anchored Proteins in <i>Candida albicans</i>
Richard, M. L., & Plaine, A. (2007) · Eukaryotic Cell · doi:10.1128/ec.00297-06 · Cited by 159 · see citing works
Fungal heat-shock proteins in human disease
Burnie, J., Carter, T. L., Hodgetts, S. J., & Matthews, R. (2005) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2005.00001.x · Cited by 158 · see citing works
Guinan, J., Wang, S., Hazbun, T. R., Yadav, H., & Thangamani, S. (2019) · Scientific Reports · doi:10.1038/s41598-019-45467-7 · Cited by 158 · see citing works
Tati, S., Davidow, P., McCall, A. D., Hwang-Wong, E., Rojas, I. G., Cormack, B. P., & Edgerton, M. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005522 · Cited by 142 · see citing works
Secreted Aspartic Proteinase Family of Candida tropicalis
Zaugg, C., Zepelin, M. B., Reichard, U., Sanglard, D., & Monod, M. (2001) · Infection and Immunity · doi:10.1128/iai.69.1.405-412.2001 · Cited by 135 · see citing works
Portrait of Candida Species Biofilm Regulatory Network Genes
Araújo, D., Henriques, M., & Silva, S. M. (2016) · Trends in Microbiology · doi:10.1016/j.tim.2016.09.004 · Cited by 135 · see citing works
Schönherr, F. A., Sparber, F., Kirchner, F. R., Guiducci, E., Trautwein-Weidner, K., Gladiator, A., Sertour, N., Hetzel, U., Le, G. T. T., Pavelka, N., et al. (2017) · Mucosal Immunology · doi:10.1038/mi.2017.2 · Cited by 133 · see citing works
Gácser, A., Schäfer, W., Nosanchuk, J. S., Salomon, S., & Nosanchuk, J. D. (2007) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2007.02.002 · Cited by 132 · see citing works
Murciano, C., Moyes, D., Runglall, M., Tobouti, P., Islam, A., Hoyer, L., & Naglik, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033362 · Cited by 124 · see citing works
The biology of mating in Candida albicans
Johnson, A. D. (2003) · Nature Reviews Microbiology · doi:10.1038/nrmicro752 · Cited by 123 · see citing works
A Core Filamentation Response Network in Candida albicans Is Restricted to Eight Genes
Martin, R., Albrecht-Eckardt, D., Brunke, S., Hube, B., Hünniger, K., & Kurzai, O. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058613 · Cited by 122 · see citing works
Stress-Induced Phenotypic Switching in Candida albicans
Alby, K., & Bennett, R. J. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e09-01-0040 · Cited by 119 · see citing works
Iron at the Centre of Candida albicans Interactions
Fourie, R., Kuloyo, O. O., Mochochoko, B. M., Albertyn, J., & Pohl, C. H. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00185 · Cited by 118 · see citing works
The Relation between Oral Candida Load and Bacterial Microbiome Profiles in Dutch Older Adults
Kraneveld, E. A., Buijs, M. J., Bonder, M. J., Visser, M., Keijser, B. J. F., Crielaard, W., & Zaura, E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042770 · Cited by 118 · see citing works
Lane, S., Zhou, S., Pan, T., Dai, Q., & Liu, H. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.19.6418-6428.2001 · Cited by 118 · see citing works
The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage
Wilson, D., Naglik, J. R., & Hube, B. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005867 · Cited by 116 · see citing works
Genetics of Candida albicans, a Diploid Human Fungal Pathogen
Noble, S. M., & Johnson, A. D. (2007) · Annual Review of Genetics · doi:10.1146/annurev.genet.41.042007.170146 · Cited by 115 · see citing works
Towards a balanced view of the bacterial tree of life
Schulz, F., Eloe-Fadrosh, E., Bowers, R., Jarett, J., Nielsen, T., Ivanova, N., Kyrpides, N., & Woyke, T. (2017) · Microbiome · doi:10.1186/s40168-017-0360-9 · Cited by 114 · see citing works
Swidergall, M., Khalaji, M., Solis, N. V., Moyes, D. L., Drummond, R. A., Hube, B., Lionakis, M. S., Murdoch, C., Filler, S. G., & Naglik, J. R. (2019) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiz322 · Cited by 113 · see citing works
IL-1 Coordinates the Neutrophil Response to C. albicans in the Oral Mucosa
Altmeier, S., Toska, A., Sparber, F., Teijeira, A., Halin, C., & LeibundGut-Landmann, S. (2016) · PLOS Pathogens · doi:10.1371/journal.ppat.1005882 · Cited by 112 · see citing works
Dwivedi, P., Thompson, A., Xie, Z., Kashleva, H., Ganguly, S., Mitchell, A. P., & Dongari-Bagtzoglou, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016218 · Cited by 110 · see citing works
Lipolytic Enzymes Involved in the Virulence of Human Pathogenic Fungi
Park, M., Do, E., & Jung, W. H. (2013) · Mycobiology · doi:10.5941/myco.2013.41.2.67 · Cited by 110 · see citing works
Farnesol and Cyclic AMP Signaling Effects on the Hypha-to-Yeast Transition in Candida albicans
Lindsay, A. K., Deveau, A., Piispanen, A. E., & Hogan, D. A. (2012) · Eukaryotic Cell · doi:10.1128/ec.00144-12 · Cited by 110 · see citing works
Candida auris: A Review of Recommendations for Detection and Control in Healthcare Settings
Caceres, D. H., Forsberg, K., Welsh, R. M., Sexton, D. J., Lockhart, S. R., Jackson, B. R., & Chiller, T. M. (2019) · Journal of Fungi · doi:10.3390/jof5040111 · Cited by 110 · see citing works
New insights into innate immune control of systemic candidiasis
Lionakis, M. S. (2014) · Medical Mycology · doi:10.1093/mmy/myu029 · Cited by 108 · see citing works
Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization
Westman, J., Moran, G. P., Mogavero, S., Hube, B., & Grinstein, S. (2018) · mBio · doi:10.1128/mbio.01226-18 · Cited by 108 · see citing works
A feast for Candida: Metabolic plasticity confers an edge for virulence
Miramón, P., & Lorenz, M. C. (2017) · PLOS Pathogens · doi:10.1371/journal.ppat.1006144 · Cited by 106 · see citing works
Expression analysis of the lipase gene family during experimental infections and in patient samples
STEHR, F., FELK, A., GACSER, A., KRETSCHMAR, M., MAHNS, B., NEUBER, K., HUBE, B., & SCHAFER, W. (2004) · FEMS Yeast Research · doi:10.1016/s1567-1356(03)00205-8 · Cited by 105 · see citing works
Nicholls, S., Leach, M. D., Priest, C. L., & Brown, A. J. P. (2009) · Molecular Microbiology · doi:10.1111/j.1365-2958.2009.06883.x · Cited by 105 · see citing works
Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence
Richardson, J. P., Mogavero, S., Moyes, D. L., Blagojevic, M., Krüger, T., Verma, A. H., Coleman, B. M., Diaz, J. D. L. C., Schulz, D., Ponde, N. O., et al. (2018) · mBio · doi:10.1128/mbio.02178-17 · Cited by 105 · see citing works
Regulation of Candida albicans Hyphal Morphogenesis by Endogenous Signals
Kornitzer, D. (2019) · Journal of Fungi · doi:10.3390/jof5010021 · Cited by 105 · see citing works
Chew, S. Y., Chee, W. J. Y., & Than, L. T. L. (2019) · Journal of Biomedical Science · doi:10.1186/s12929-019-0546-5 · Cited by 105 · see citing works
Zeidler, U., Lettner, T., Lassnig, C., ller, M. M. ⁄., Lajko, R., Hintner, H., Breitenbach, M., & Bito, A. (2008) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2008.00459.x · Cited by 104 · see citing works
Cheah, H.-L., Lim, V., & Sandai, D. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095951 · Cited by 103 · see citing works
Gong, Y., Li, T., Yu, C., & Sun, S. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00520 · Cited by 101 · see citing works
Mayer, F. L., Wilson, D., Jacobsen, I. D., Miramón, P., Slesiona, S., Bohovych, I., Brown, A. J. P., & Hube, B. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038584 · Cited by 100 · see citing works
Yano, J., Noverr, M. C., & Fidel, P. L. (2011) · Cytokine · doi:10.1016/j.cyto.2011.11.021 · Cited by 100 · see citing works
The DNA Binding Protein Rfg1 Is a Repressor of Filamentation in Candida albicans
Khalaf, R. A., & Zitomer, R. S. (2001) · Genetics · doi:10.1093/genetics/157.4.1503 · Cited by 97 · see citing works
Morphogenesis in Fungal Pathogenicity: Shape, Size, and Surface
Wang, L., & Lin, X. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1003027 · Cited by 94 · see citing works
White-Opaque Switching of Candida albicans Allows Immune Evasion in an Environment-Dependent Fashion
Sasse, C., Hasenberg, M., Weyler, M., Gunzer, M., & Morschhäuser, J. (2012) · Eukaryotic Cell · doi:10.1128/ec.00266-12 · Cited by 93 · see citing works
Candida Interactions with the Oral Bacterial Microbiota
Montelongo‐Jauregui, D., & Lopez-Ribot, J. L. (2018) · Journal of Fungi · doi:10.3390/jof4040122 · Cited by 93 · see citing works
Lourenço, A., Pedro, N. A., Salazar, S. B., & Mira, N. P. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03265 · Cited by 93 · see citing works
Aoki, W., Kitahara, N., Miura, N., Morisaka, H., Yamamoto, Y., Kuroda, K., & Ueda, M. (2011) · Journal of Biochemistry (Tokyo) · doi:10.1093/jb/mvr073 · Cited by 92 · see citing works
The Hsp90 chaperone network modulates Candida virulence traits
O’Meara, T. R., Robbins, N., & Cowen, L. E. (2017) · Trends in Microbiology · doi:10.1016/j.tim.2017.05.003 · Cited by 92 · see citing works
IL-36 and IL-1/IL-17 drive immunity to oral candidiasis via parallel mechanisms
Verma, A. H., Zafar, H. M., Ponde, N., Hepworth, O. W., Sihra, D., Aggor, F. E. Y., Ainscough, J. S., Ho, J., Richardson, J., Coleman, B. M., et al. (2018) · Journal of Immunology · doi:10.4049/jimmunol.1800515 · Cited by 91 · see citing works
Kaloriti, D., Jacobsen, M. D., Yin, Z., Patterson, M. J., Tillmann, A., Smith, D. A., Cook, E., You, T., Grimm, M. J., Bohovych, I., et al. (2014) · mBio · doi:10.1128/mbio.01334-14 · Cited by 88 · see citing works
Lobo, C. I. V., Rinaldi, T. B., Christiano, C. M. S., Leite, L. D. S., Barbugli, P. A., & Klein, M. I. (2019) · Journal of Oral Microbiology · doi:10.1080/20002297.2019.1581520 · Cited by 87 · see citing works
The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance
Shapiro, R. S., Zaas, A. K., Betancourt-Quiroz, M., Perfect, J. R., & Cowen, L. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044734 · Cited by 86 · see citing works
The Candida albicans-Specific Gene EED1 Encodes a Key Regulator of Hyphal Extension
Martin, R., Moran, G. P., Jacobsen, I. D., Heyken, A., Domey, J., Sullivan, D. J., Kurzai, O., & Hube, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018394 · Cited by 85 · see citing works
Borelli, C., Ruge, E., Lee, J. H., Schaller, M., Vogelsang, A., Monod, M., Körting, H. C., Huber, R., & Maskos, K. (2008) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.22021 · Cited by 85 · see citing works
The role of phenotypic switching in the basic biology and pathogenesis ofCandida albicans
Soll, D. R. (2014) · Journal of Oral Microbiology · doi:10.3402/jom.v6.22993 · Cited by 83 · see citing works
Chaillot, J., Tebbji, F., Remmal, A., Boone, C., Brown, G. W., Bellaoui, M., & Sellam, A. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00551-15 · Cited by 82 · see citing works
Sachin, C. D., Katiyar, R., & Santosh Kumar, H. S. (2012) · International Journal of Medicine and Biomedical Research · doi:10.14194/ijmbr.1211 · Cited by 80 · see citing works
Cytoplasmic Alkalinization during Germ Tube Formation in Candida albicans
Stewart, E., Gow, N. A. R., & BOWEN, D. V. (1988) · Microbiology · doi:10.1099/00221287-134-5-1079 · Cited by 77 · see citing works
Reedy, J. L., Filler, S. G., & Heitman, J. (2010) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2009.09.002 · Cited by 76 · see citing works
Xie, J., Du, H., Guan, G., Tong, Y., Kourkoumpetis, T. K., Zhang, L., Bai, F., & Huang, G. (2012) · Eukaryotic Cell · doi:10.1128/ec.00047-12 · Cited by 74 · see citing works
Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids
Danhof, H. A., Vylkova, S., Vesely, E. M., Ford, A. E., Gonzalez‐Garay, M. L., & Lorenz, M. C. (2016) · mBio · doi:10.1128/mbio.01646-16 · Cited by 72 · see citing works
Cabral, D. J., Penumutchu, S., Norris, C., Morones‐Ramírez, J. R., & Belenky, P. A. (2018) · Microbial Cell · doi:10.15698/mic2018.05.631 · Cited by 72 · see citing works
Carlisle, P. L., & Kadosh, D. (2010) · Eukaryotic Cell · doi:10.1128/ec.00046-10 · Cited by 71 · see citing works
Leonhardt, I., Spielberg, S., Weber, M., Albrecht-Eckardt, D., Blaess, M. F., Claus, R. A., Barz, D., Scherlach, K., Hertweck, C., Löffler, J., et al. (2015) · mBio · doi:10.1128/mbio.00143-15 · Cited by 71 · see citing works
Protease and phospholipase activities of Candida spp. isolated from cutaneous candidiasis
Ramos, L. S., Barbedo, L. S., Braga-Silva, L. A., dos Santos, A. L. S., Pinto, M. R., & Sgarbi, D. B. D. G. (2014) · Revista Iberoamericana de Micología · doi:10.1016/j.riam.2014.01.003 · Cited by 70 · see citing works
Han, T.-L., Cannon, R. D., Gallo, S. M., & Villas-Bôas, S. G. (2019) · npj Biofilms and Microbiomes · doi:10.1038/s41522-019-0086-5 · Cited by 67 · see citing works
Effect of Growth Media, pH and Temperature on Yeast to Hyphal Transition in Candida albicans
Nadeem, S. G., Shafiq, A., Hakim, S. T., Anjum, Y., & Kazm, S. U. (2013) · Open Journal of Medical Microbiology · doi:10.4236/ojmm.2013.33028 · Cited by 66 · see citing works
Zhou, Y., Liao, M., Zhu, C., Hu, Y. H., Tong, T., Peng, X., Li, M., Feng, M., Cheng, L., Ren, B., et al. (2018) · International Journal of Oral Science · doi:10.1038/s41368-018-0013-2 · Cited by 66 · see citing works
Ras Signaling Gets Fine-Tuned: Regulation of Multiple Pathogenic Traits of Candida albicans
Inglis, D. O., & Sherlock, G. (2013) · Eukaryotic Cell · doi:10.1128/ec.00094-13 · Cited by 65 · see citing works
Impact of surface topography on biofilm formation by Candida albicans
Lagree, K., Mon, H. H., Mitchell, A. P., & Ducker, W. A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0197925 · Cited by 65 · see citing works
Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens
Sharma, J., Rosiana, S., Razzaq, I., & Shapiro, R. S. (2019) · Journal of Fungi · doi:10.3390/jof5010017 · Cited by 64 · see citing works
Pandey, N., Gupta, M. K., & Tilak, R. (2018) · Journal of Laboratory Physicians · doi:10.4103/jlp.jlp_81_18 · Cited by 64 · see citing works
Comparison of the hemolytic activity between C. albicans and non-albicans Candida species
Rossoni, R. D., Barbosa, J. O., Vilela, S. F. G., Jorge, A. O. C., & Junqueira, J. C. (2013) · Brazilian Oral Research · doi:10.1590/s1806-83242013000600007 · Cited by 62 · see citing works
Samaranayake, Y. H., Dassanayake, R. S., Cheung, B. P. K., Jayatilake, J. A. M. S., Yeung, K. W. S., Yau, J. Y. Y., & Samaranayake, L. P. (2006) · Apmis · doi:10.1111/j.1600-0463.2006.apm_479.x · Cited by 59 · see citing works
Calcineurin signaling: lessons from Candida species
Yu, S.-J., Chang, Y.-L., & Chen, Y. (2015) · FEMS Yeast Research · doi:10.1093/femsyr/fov016 · Cited by 58 · see citing works
Chong, P. P., Chin, V. K., Wong, W. F., Madhavan, P., Yong, P. V. C., & Looi, C. Y. (2018) · Genes · doi:10.3390/genes9110540 · Cited by 56 · see citing works
Lin, C.-J., & Chen, Y.-L. (2018) · Journal of Fungi · doi:10.3390/jof4020068 · Cited by 55 · see citing works
Glazier, V. E., Murante, T., Murante, D., Koselny, K., Liu, Y., Kim, D., Koo, H., & Krysan, D. J. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006948 · Cited by 54 · see citing works
Mishra, R., van Drogen, F., Dechant, R. C., Oh, S., Jeon, N. L., Lee, S. S., & Peter, M. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1709079114 · Cited by 54 · see citing works
Reyna‐Beltrán, E., Iranzo, M., Calderón-González, K. G., Mondragón‐Flores, R., Labra‐Barrios, M. L., Mormeneo, S., & Luna‐Arias, J. P. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.810440 · Cited by 54 · see citing works
Study of Candida albicans and its interactions with the host: A mini review
Tsai, P.-W., Chen, Y.-T., Hsu, P., & Lan, C. (2013) · Biomedicine · doi:10.1016/j.biomed.2012.12.004 · Cited by 53 · see citing works
Subramanya, S. H., Sharan, N. K., Baral, B. P., Hamal, D., Nayak, N., Prakash, P. Y., Sathian, B., Bairy, I., & Gokhale, S. (2017) · BMC Microbiology · doi:10.1186/s12866-017-1024-4 · Cited by 53 · see citing works
Kadry, A. A., El-Ganiny, A. M., & El-Baz, A. M. (2018) · African Health Sciences · doi:10.4314/ahs.v18i4.37 · Cited by 53 · see citing works
Heat shock protein 60: Identification of specific epitopes for binding to primary macrophages
Habich, C., Kempe, K., Gómez, F. J., Lillicrap, M., Gaston, H., van der Zee, R., Kolb, H., & Burkart, V. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.11.060 · Cited by 52 · see citing works
Invasive candidiasis and candidemia: new guidelines.
Rosa, F. G. D., Garazzino, S., Pasero, D., Perri, G. D., & Ranieri, V. M. (2009) · PubMed · Cited by 52 · see citing works
Ingham, C. J., Boonstra, S., Levels, S., de Lange, M., Meis, J. F. G. M., & Schneeberger, P. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033818 · Cited by 51 · see citing works
Koch, B., Barugahare, A. A., Lo, T. L., Huang, C., Schittenhelm, R. B., Powell, D. R., Beilharz, T. H., & Traven, A. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.10.080 · Cited by 50 · see citing works
Candida albicans Pma1p Contributes to Growth, pH Homeostasis, and Hyphal Formation
Rane, H. S., Hayek, S. R., Frye, J. E., Abeyta, E. L., Bernardo, S. M., Parra, K. J., & Lee, S. A. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01012 · Cited by 50 · see citing works
Coupling temperature sensing and development
Shapiro, R. S., & Cowen, L. E. (2010) · Virulence · doi:10.4161/viru.1.1.10320 · Cited by 49 · see citing works
O'Meara, T. R., & Cowen, L. E. (2014) · Cellular Microbiology · doi:10.1111/cmi.12266 · Cited by 48 · see citing works
Gang-sheng, W. A. N. G., Deng, J., Ma, Y., Min, S. H. I., & Li, B. (2012) · 中医杂志:英文版 · doi:10.1016/s0254-6272(12)60026-0 · Cited by 46 · see citing works
Role of Heat Shock Proteins in Diseases and Their Therapeutic Potential
Kaul, G., & Thippeswamy, H. (2011) · Indian Journal of Microbiology · doi:10.1007/s12088-011-0147-9 · Cited by 46 · see citing works
pH Regulates White-Opaque Switching and Sexual Mating in Candida albicans
Sun, Y., Cao, C., Jia, W., Li, T., Guan, G., & Huang, G. (2015) · Eukaryotic Cell · doi:10.1128/ec.00123-15 · Cited by 46 · see citing works
Laurian, R., Dementhon, K., Doumèche, B., Soulard, A., Noël, T., Lemaire, M., & Cotton, P. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00327 · Cited by 46 · see citing works
Candida albicans-secreted lipase induces injury and steatosis in immune and parenchymal cells
Paraje, M. G., Correa, S. G., Renna, M. S., Theumer, M. G., & Sotomayor, C. E. (2008) · Canadian Journal of Microbiology · doi:10.1139/w08-048 · Cited by 45 · see citing works
Candida albicans morphology: still in focus
Jacobsen, I. D., & Hube, B. (2017) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2017.1290524 · Cited by 45 · see citing works
Panariello, B. H. D., Klein, M. I., Pavarina, A. C., & Duarte, S. (2017) · Journal of Oral Microbiology · doi:10.1080/20002297.2017.1385372 · Cited by 45 · see citing works
Meenambiga, S. S., Venkataraghavan, R., & Biswal, R. A. (2018) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2018.81120 · Cited by 45 · see citing works
Seman, B. G., Moore, J. L., Scherer, A. K., Blair, B. A., Manandhar, S., Jones, J. M., & Wheeler, R. T. (2018) · Infection and Immunity · doi:10.1128/iai.00415-18 · Cited by 44 · see citing works
Progress and prospects for targeting Hsp90 to treat fungal infections
Veri, A. O., & Cowen, L. E. (2014) · Parasitology · doi:10.1017/s0031182013002072 · Cited by 43 · see citing works
Kos, I., Patterson, M. J., Znaidi, S., Kaloriti, D., Dantas, A. D. S., Herrero-de-Dios, C. M., d’Enfert, C., Brown, A. J. P., & Quinn, J. (2016) · mBio · doi:10.1128/mbio.00331-16 · Cited by 43 · see citing works
Cabral, D. J., Wurster, J. I., Flokas, M. E., Alevizakos, M., Zabat, M. A., Korry, B. J., Rowan-Nash, A. D., Sano, W. H., Andreatos, N., Ducharme, R., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-11427-2 · Cited by 43 · see citing works
Yu, Q., Jia, C., Dong, Y., Zhang, B., Xiao, C., Chen, Y., Wang, Y., Li, X., Wang, L., Zhang, B., et al. (2015) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2015.02.008 · Cited by 42 · see citing works
Candida tropicalis affects the virulence profile of Candida albicans: an in vitro and in vivo study
de Barros, P. P., Rossoni, R. D., Freire, F., Ribeiro, F. D. C., Lopes, L. A. D. C., Junqueira, J. C., & Jorge, A. O. C. (2018) · Pathogens and Disease · doi:10.1093/femspd/fty014 · Cited by 42 · see citing works
Enzymatic and hemolytic activities of Candida dubliniensis strains
Linares, C. E. B., Loreto, É. S., Silveira, C. P., Pozzatti, P., Scheid, L. A., Santúrio, J. M., & Alves, S. H. (2007) · Revista do Instituto de Medicina Tropical de São Paulo · doi:10.1590/s0036-46652007000400001 · Cited by 39 · see citing works
Regulatory Circuits That Enable Proliferation of the Fungus Candida albicans in a Mammalian Host
Pérez, J. C., & Johnson, A. D. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003780 · Cited by 38 · see citing works
İnci, M., ATALAY, M. A., Koç, A. N., Yula, E., Evirgen, Ö., Durmaz, S., & Demir, G. (2012) · TURKISH JOURNAL OF MEDICAL SCIENCES · doi:10.3906/sag-1204-119 · Cited by 38 · see citing works
Fu, Y., Phan, Q. T., Luo, G., Solis, N. V., Liu, Y., Cormack, B. P., Edwards, J. E., Ibrahim, A. S., & Filler, S. G. (2013) · Infection and Immunity · doi:10.1128/iai.00013-13 · Cited by 37 · see citing works
Epithelial discrimination of commensal and pathogenic Candida albicans
Tang, S. X., Moyes, D. L., Richardson, J., Blagojevic, M., & Naglik, J. R. (2016) · Oral Diseases · doi:10.1111/odi.12395 · Cited by 37 · see citing works
Spitzer, M., & Wiederhold, N. P. (2018) · Journal of Lower Genital Tract Disease · doi:10.1097/lgt.0000000000000383 · Cited by 37 · see citing works
Functional Characterization of the Small Heat Shock Protein Hsp12p from Candida albicans
Fu, M. S., Sordi, L. D., & Mühlschlegel, F. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042894 · Cited by 35 · see citing works
The Role of Candida albicans SPT20 in Filamentation, Biofilm Formation and Pathogenesis
Tan, X., Fuchs, B. B., Wang, Y., Chen, W., Yuen, G. J., Chen, R. B., Jayamani, E., Anastassopoulou, C. G., Pukkila-Worley, R., Coleman, J. J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094468 · Cited by 35 · see citing works
Alkafeef, S. S., Yu, C., Huang, L., & Liu, H. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007176 · Cited by 34 · see citing works
Functional diversification accompanies gene family expansion of MED2 homologs in Candida albicans
Dunn, M. J., Kinney, G. M., Washington, P. M., Berman, J. G., & Anderson, M. Z. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007326 · Cited by 34 · see citing works
Camarillo-Márquez, O., Córdova-Alcántara, I. M., Hernández, G., García‐Pérez, B. E., Martínez-Rivera, M. Á., & Rodríguez-Tovar, A. V. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02031 · Cited by 34 · see citing works
Li, L., Zhang, T., Xu, J., Wu, J., Wang, Y., Qiu, X.-R., Zhang, Y., Hou, W.-T., Yan, L., An, M., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02071 · Cited by 34 · see citing works
Treatment strategies for oropharyngeal candidiasis
Laudenbach, J. M., & Epstein, J. B. (2009) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656560902952854 · Cited by 33 · see citing works
Saputo, S., Kumar, A., & Krysan, D. J. (2014) · Eukaryotic Cell · doi:10.1128/ec.00148-14 · Cited by 32 · see citing works
Li, L., Liao, Z., Yang, Y., Lv, L., Cao, Y., & Zhu, Z. (2018) · PLoS ONE · doi:10.1371/journal.pone.0192328 · Cited by 31 · see citing works
Solis, N. V., Park, Y., Swidergall, M., Daniels, K. J., Filler, S. G., & Soll, D. R. (2018) · Infection and Immunity · doi:10.1128/iai.00774-17 · Cited by 31 · see citing works
In vitro evaluation of virulence factors of Candida species isolated from oral cavity
Deepa, K., Jeevitha, T., & Michael, A. (2015) · Journal of Microbiology and Antimicrobials · doi:10.5897/jma2015.0337 · Cited by 30 · see citing works
Protein kinase A governs growth and virulence in Candida tropicalis
Lin, C.-J., Wu, C.-Y., Yu, S.-J., & Chen, Y. (2017) · Virulence · doi:10.1080/21505594.2017.1414132 · Cited by 30 · see citing works
Jacobsen, M. D., Beynon, R. J., Gethings, L. A., Claydon, A. J., Langridge, J., Vissers, J. P. C., Brown, A. J. P., & Hammond, D. E. (2018) · Scientific Reports · doi:10.1038/s41598-018-32792-6 · Cited by 30 · see citing works
Differential Response of Candida albicans and Candida glabrata to Oxidative and Nitrosative Stresses
Cuéllar‐Cruz, M., López-Romero, E., Ruiz‐Baca, E., & Zazueta‐Sandoval, R. (2014) · Current Microbiology · doi:10.1007/s00284-014-0651-3 · Cited by 29 · see citing works
Perini, H. F., Moralez, A. T. P., Almeida, R. S., Panagio, L. A., Admilton, O. G., Barcellos, F. G., Furlaneto-Maia, L., & Furlaneto, M. C. (2019) · Scientific Reports · doi:10.1038/s41598-019-49080-6 · Cited by 29 · see citing works
Filamentation Is Associated with Reduced Pathogenicity of Multiple Non- albicans Candida Species
Banerjee, M., Lazzell, A. L., Romo, J. A., Lopez-Ribot, J. L., & Kadosh, D. (2019) · mSphere · doi:10.1128/msphere.00656-19 · Cited by 29 · see citing works
Regulation of hyphal morphogenesis by Ras and Rho small GTPases
Arkowitz, R. A., & Bassilana, M. (2015) · Fungal Biology Reviews · doi:10.1016/j.fbr.2015.02.003 · Cited by 28 · see citing works
Identification of Candida albicans regulatory genes governing mucosal infection
Meir, J., Hartmann, E., Eckstein, M.-T., Guiducci, E., Kirchner, F. R., Rosenwald, A., Leibundgut-Landmann, S., & Pérez, J. C. (2018) · Cellular Microbiology · doi:10.1111/cmi.12841 · Cited by 28 · see citing works
Desai, J. V., Cheng, S., Ying, T., Nguyen, M. H., Clancy, C. J., Lanni, F., & Mitchell, A. P. (2015) · Pathogens · doi:10.3390/pathogens4030573 · Cited by 27 · see citing works
Chin, V. K., Foong, K.-J., Maha, A., Rusliza, B., Norhafizah, M. Z., Ng, K. P., & Chong, P. P. (2013) · PubMed · Cited by 26 · see citing works
Restraining Pathogenicity in Candida albicans by Taxifolin as an Inhibitor of Ras1-pka Pathway
Mishra, S., Singh, S., & Misra, K. (2017) · Mycopathologia · doi:10.1007/s11046-017-0170-4 · Cited by 26 · see citing works
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Lass‐Flörl, C., Kanj, S. S., Govender, N. P., Thompson, G. R., Ostrosky-Zeichner, L. L., & Govrins, M. A. (2024) · Nature Reviews Disease Primers · doi:10.1038/s41572-024-00503-3 · Cited by 319 · see citing works
Santus, W., Devlin, J. R., & Behnsen, J. (2021) · Infection and Immunity · doi:10.1128/iai.00648-20 · Cited by 132 · see citing works
El-Baz, A. M., Mosbah, R., Goda, R. M., Mansour, B., Sultana, T., Dahms, T. E. S., & El-Ganiny, A. M. (2021) · Antibiotics · doi:10.3390/antibiotics10010081 · Cited by 80 · see citing works
Gaziano, R., Sabbatini, S., & Monari, C. (2023) · Microorganisms · doi:10.3390/microorganisms11051211 · Cited by 81 · see citing works
What Do We Know about Candida auris? State of the Art, Knowledge Gaps, and Future Directions
García-Bustos, V., Cabañero-Navalón, M. D., Ruiz‐Saurí, A., Gaitán, A. C. R., Salavert, M., Tormo‐Más, M. Á., & Pemán, J. (2021) · Microorganisms · doi:10.3390/microorganisms9102177 · Cited by 82 · see citing works
Ahmed, N., Mahmood, M. S., Ullah, M. A., Araf, Y., Rahaman, T. I., Moin, A. T., & Hosen, M. J. (2022) · Current Microbiology · doi:10.1007/s00284-022-02824-6 · Cited by 79 · see citing works
Advances in the structures, mechanisms and targeting of molecular chaperones
Gu, J., He, Y., He, C., Zhang, Q., Huang, Q., Bai, S., Wang, R., You, Q., & Wang, L. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02166-2 · Cited by 72 · see citing works
Contaldo, M., Stasio, D. D., Romano, A., Fiori, F., della Vella, F., Rupe, C., Lajolo, C., Petruzzi, M., Serpico, R., & Lucchese, A. (2022) · Current Drug Delivery · doi:10.2174/1567201819666220418104042 · Cited by 67 · see citing works
Natural Compounds: A Hopeful Promise as an Antibiofilm Agent Against Candida Species
Shariati, A., Didehdar, M., Razavi, S., Heidary, M., Soroush, F., & Chegini, Z. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.917787 · Cited by 72 · see citing works
Garcia-Bustos, V., Ruiz-Saurí, A., Ruiz-Gaitán, A., Sigona-Giangreco, I. A., Cabañero-Navalon, M. D., Sabalza-Baztán, O., Salavert-Lletí, M., Tormo, M. Á., & Pemán, J. (2021) · Microbiology Spectrum · doi:10.1128/spectrum.00013-21 · Cited by 66 · see citing works
Antimicrobial Properties of Antidepressants and Antipsychotics—Possibilities and Implications
Caldara, M., & Marmiroli, N. (2021) · Pharmaceuticals · doi:10.3390/ph14090915 · Cited by 54 · see citing works
Antifungal drug resistance in Candida: a special emphasis on amphotericin B
Ahmady, L., Gothwal, M., Mukkoli, M. M., & Bari, V. K. (2024) · Apmis · doi:10.1111/apm.13389 · Cited by 58 · see citing works
Raza, S., Wdowiak, M., Grotek, M., Adamkiewicz, W., Nikiforow, K., Mente, P., & Paczesny, J. (2023) · Nanoscale Advances · doi:10.1039/d3na00220a · Cited by 48 · see citing works
Mba, I. E., & Nweze, E. I. (2020) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-020-02940-0 · Cited by 49 · see citing works
Self-citationFarrokhi, Y., Al-shibli, B., Al-Hameedawi, D. F., Neshati, Z., & Makhdoumi, A. (2021) · Research in Microbiology · doi:10.1016/j.resmic.2021.103849 · Cited by 49 · see citing works
The research progress in the interaction between Candida albicans and cancers
Yu, D., & Liu, Z. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.988734 · Cited by 47 · see citing works
We need to talk about Candida tropicalis : Virulence factors and survival mechanisms
dos Santos, M. M., & Ishida, K. (2023) · Medical Mycology · doi:10.1093/mmy/myad075 · Cited by 50 · see citing works
Mba, I. E., Nweze, E. I., Eze, E. A., & Anyaegbunam, Z. K. G. (2022) · Infection, Genetics and Evolution · doi:10.1016/j.meegid.2022.105256 · Cited by 46 · see citing works
Self-citationPalmieri, F., Koutsokera, A., Bernasconi, E., Junier, P., von Garnier, C., & Ubags, N. D. J. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.832510 · Cited by 50 · see citing works
Opportunistic yeast pathogen Candida spp.: Secreted and membrane-bound virulence factors.
Lim, S. J., Ali, M., Sabri, S., Noor, N. D. M., Salleh, A., & Oslan, S. N. (2021) · Medical Mycology · doi:10.1093/mmy/myab053 · Cited by 40 · see citing works
Chevecich, C. C., Müller-Sepúlveda, A., Jara, J. A., López‐Muñoz, R., Santander, R., Budini, M., Escobar, A. F., Quijada, R., Criollo, A., Díaz‐Dosque, M., et al. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-022-03518-z · Cited by 35 · see citing works
Garcia-Bustos, V., Pemán, J., Ruiz-Gaitán, A., Cabañero-Navalon, M. D., Cabanilles-Boronat, A., Fernández-Calduch, M., Marcilla-Barreda, L., Sigona-Giangreco, I. A., Salavert, M., Tormo-Mas, M. Á., et al. (2022) · Emerging Microbes & Infections · doi:10.1080/22221751.2021.2017756 · Cited by 30 · see citing works
Chen, J.-Z., Hu, N., Xu, H., Liu, Q., Yu, X., Zhang, Y., Huang, Y., Tan, J., Huang, X., & Zeng, L. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.721439 · Cited by 31 · see citing works
Rupe, C., Gioco, G., Almadori, G., Galli, J., Miccichè, F., Olivieri, M., Cordaro, M., & Lajolo, C. (2022) · Cancers · doi:10.3390/cancers14194746 · Cited by 27 · see citing works
Commensal yeast promotes Salmonella Typhimurium virulence
Jaswal, K., Todd, O. A., Audelo, R. C. F., Santus, W., Paul, S., Duffy, C. M., Eshoo, E. T., Singh, M. B., Miao, J., Underhill, D. M., et al. (2025) · Nature · doi:10.1038/s41586-025-09415-y · Cited by 28 · see citing works
Nanotechnology-Based Strategies to Combat Multidrug-Resistant Candida auris Infections
Hetta, H. F., Ramadan, Y. N., Al-Kadmy, I. M. S., Ellah, N. H. A., Shbibe, L., & Battah, B. (2023) · Pathogens · doi:10.3390/pathogens12081033 · Cited by 24 · see citing works
Lima, H. V. D., Cavalcante, C. S. D. P., & Rádis‐Baptista, G. (2020) · Antibiotics · doi:10.3390/antibiotics9060354 · Cited by 24 · see citing works
Hameed, S., Hans, S., Monasky, R. C., Thangamani, S., & Fatima, Z. (2021) · Pathogens · doi:10.3390/pathogens10020183 · Cited by 23 · see citing works
Invasive Candidiasis in the Intensive Care Unit: Where Are We Now?
Vázquez, J. A., Whitaker, L., & Zubovskaia, A. (2025) · Journal of Fungi · doi:10.3390/jof11040258 · Cited by 24 · see citing works
Esmaeili, A., Saleh, I., & Abu‐Dieyeh, M. H. (2025) · Phytochemistry Reviews · doi:10.1007/s11101-025-10093-x · Cited by 31 · see citing works
Contaldo, M. (2023) · Frontiers in Bioscience-Elite · doi:10.31083/j.fbe1501006 · Cited by 19 · see citing works
Meylani, V., Putra, R. R., Miftahussurur, M., Sukardiman, S., Hermanto, F. E., & Abdullah, A. (2022) · Results in Chemistry · doi:10.1016/j.rechem.2022.100721 · Cited by 16 · see citing works
Profiling of potential pathogenic candida species in obesity.
Shoukat, M., Ullah, F., Tariq, M. N., Din, G., Khadija, B., & Faryal, R. (2022) · Microbial Pathogenesis · doi:10.1016/j.micpath.2022.105894 · Cited by 14 · see citing works
Aydın, M., Ünüsan, N., Şumlu, E., & Korucu, E. N. (2024) · Journal of Fungi · doi:10.3390/jof10110751 · Cited by 15 · see citing works
Szibor, M., Schenkl, C., Barsottini, M. R. D. O., Young, L., & Moore, A. L. (2022) · Biochemical Journal · doi:10.1042/bcj20180192 · Cited by 15 · see citing works
Yang, Z., Yang, M., Deehan, E. C., Cai, C., Madsen, K. L., Wine, E., Li, G., Li, J., Liu, J., & Zhang, Z. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2387796 · Cited by 17 · see citing works
Ellagic Acid Potentiates the Inhibitory Effects of Fluconazole Against Candida albicans
Mendes, A. G. G., Campos, C. D. L., Filho, J. L. P., Pereira, A. P. A., Reis, G. S. A., Araújo, Á. W. M. D. S., Monteiro, P. D. M., Vidal, F. C. B., Monteiro, S. G., Figueiredo, I. F. D. S., et al. (2024) · Antibiotics · doi:10.3390/antibiotics13121174 · Cited by 14 · see citing works
Shigeishi, H., Nakamura, M., Oka, I., Su, C.-Y., Yano, K., Ishikawa, M., Kaneyasu, Y., Sugiyama, M., & Ohta, K. (2021) · Diagnostics · doi:10.3390/diagnostics11081397 · Cited by 13 · see citing works
Chilamakuri, S. N., Kumar, A., Nath, A. G., Gupta, A., Selvaraju, S., Basrani, S. T., Jadhav, A. K., & Gulbake, A. (2023) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2023.11.031 · Cited by 13 · see citing works
Materials used to prevent adhesion, growth, and biofilm formation ofCandidaspecies
Tornero-Gutiérrez, F., Ortiz-Ramírez, J. A., López-Romero, E., & Cuéllar‐Cruz, M. (2023) · Medical Mycology · doi:10.1093/mmy/myad065 · Cited by 13 · see citing works
“Click” amphotericin B in prodrug nanoformulations for enhanced systemic fungemia treatment
Guo, D., Shi, C., Suo, L., Ji, X., Yue, H., Yuan, D., & Luo, J. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.05.003 · Cited by 13 · see citing works
Silva, N. B. S., Menezes, R. D. P., Gonçalves, D. S., Santiago, M. B., Conejo, N. C., Souza, S. L., Santos, A. L. O., Silva, R. S., Ramos, S. B., Ferro, E. A. V., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-61179-z · Cited by 11 · see citing works
Characterization of susceptibility patterns and adaptability of the newly emerged Candida auris
Semenya, M. D., Aladejana, A. E., & Ndlovu, S. I. (2024) · International Microbiology · doi:10.1007/s10123-024-00563-1 · Cited by 14 · see citing works
Cyclic strain of poly (methyl methacrylate) surfaces triggered the pathogenicity of Candida albicans
Montoya, C., Kurylec, J., Ossa, A., & Orrego, S. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.08.037 · Cited by 14 · see citing works
Padmavathi, A. R., Reddy, G. K. K., Murthy, P. S., & Nancharaiah, Y. V. (2024) · Microbial Pathogenesis · doi:10.1016/j.micpath.2024.106800 · Cited by 11 · see citing works
Sahoo, B., Goyal, R., Dutta, S., Joshi, P., & Sanyal, K. (2025) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.5c00079 · Cited by 12 · see citing works
Swingler, S., Gupta, A., Gibson, H., Heaselgrave, W., Kowalczuk, M. M., Adamus, G., & Radecka, I. (2021) · Materials · doi:10.3390/ma14102654 · Cited by 10 · see citing works
Rana, A., Gupta, N., & Thakur, A. (2021) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2021.101017 · Cited by 11 · see citing works
Coinfection of fungi with SARS-CoV-2 is a detrimental health risk for COVID-19 patients
Baten, N., Wajed, S., Talukder, A., Masum, M. H. U., & Rahman, M. M. (2022) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-022-00245-9 · Cited by 9 · see citing works
Chen, M., Shi, G., Dai, Y., Fang, W., & Wu, Q. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1133593 · Cited by 10 · see citing works
Ssa1-targeted antibody prevents host invasion by Candida albicans
Qiu, X.-R., Shen, C.-R., Jiang, L., Ji, P., Zhang, Y., Hou, W.-T., Zhang, W., Shen, H., & An, M. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1182914 · Cited by 8 · see citing works
SarveAhrabi, Y., & Khoei, S. N. (2023) · Journal of Skin and Stem Cell · doi:10.5812/jssc-142360 · Cited by 8 · see citing works
Candida albicans antibiofilm molecules: analysis based on inhibition and eradication studies
Guimarães, C. D. R. E., de Freitas, H. F., & Barros, T. F. (2022) · Brazilian Journal of Microbiology · doi:10.1007/s42770-022-00876-1 · Cited by 8 · see citing works
Adelakun, A. O., Awosika, A., Adabanya, U., Omole, A. E., Olopoda, A. I., & Bello, E. T. (2024) · Cureus · doi:10.7759/cureus.52857 · Cited by 8 · see citing works
Detection of ERG11 gene in fluconazole resistant urinary candida isolates
Said, M. E., Badawi, H., Gamal, D., Salem, D., Dahroug, H., & El-Far, A. (2022) · Egyptian journal of Immunology · doi:10.55133/eji.290413 · Cited by 8 · see citing works
Soliman, S. S. M. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1258837 · Cited by 8 · see citing works
Oganesyan, E. G., Klimenteva, V., Vybornova, I. V., Venchakova, V. V., Parshikova, E., Kovyrshin, S., Oe, O., Kruglov, A., Александровна, Г. С., Vasilyeva, N. V., et al. (2025) · Journal of Fungi · doi:10.3390/jof11010035 · Cited by 7 · see citing works
Molaeitabari, A., & Dahms, T. E. S. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.02754-24 · Cited by 7 · see citing works
Impeding Virulence of Candida albicans by Candesartan and Domperidone
Abbas, H. A., Gad, A. I., El-Sayed, M. A., & El-Ganiny, A. M. (2021) · Current Microbiology · doi:10.1007/s00284-021-02663-x · Cited by 9 · see citing works
Gentile, P., Ragusa, E., Bruno, R., Ceccarelli, F., Adani, C., Bolletta, E., Simone, L. D., Gozzi, F., & Cimino, L. (2025) · Ocular Immunology and Inflammation · doi:10.1080/09273948.2025.2524013 · Cited by 6 · see citing works
Rolim, P. A. D. S., Catanoze, I. A., Fracasso, J. A. R., Barbosa, D. B., dos Santos, L., Ximenes, V. F., & Guiotti, A. M. (2024) · Cosmetics · doi:10.3390/cosmetics11050162 · Cited by 6 · see citing works
Production and Isolation of the Candida Species Biofilm Extracellular Matrix
Heredia, M. Y., & Andes, D. R. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2549-1_19 · Cited by 6 · see citing works
Effects of resveratrol on macrophages after phagocytosis of Candida glabrata
Chen, Z.-H., Guan, M., & Zhao, W. (2023) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2023.151589 · Cited by 6 · see citing works
Mba, I. E., & Nweze, E. I. (2019) · Bio Research Journal/Bio- Research · doi:10.4314/br.v17i1.4 · Cited by 5 · see citing works
Self-citationAldrees, A., Ghonem, L., Almajid, F. M., Barry, M. A., Mayet, A. Y., & Almohaya, A. M. (2021) · Antibiotics · doi:10.3390/antibiotics10121498 · Cited by 5 · see citing works
Prusty, J. S., & Kumar, A. (2024) · Journal of Proteomics · doi:10.1016/j.jprot.2024.105228 · Cited by 5 · see citing works
Brikci-Benhabib, O. B., Boucherit‐Otmani, Z., Boucherit, K., & Djédiat, C. (2020) · Microbial Pathogenesis · doi:10.1016/j.micpath.2020.104613 · Cited by 5 · see citing works
Huang, Z., Dai, H., Zhang, X., Wang, Q., Sun, J., Deng, Y., & Shi, P. (2021) · Cellular Microbiology · doi:10.1111/cmi.13391 · Cited by 5 · see citing works
Vaginal Infection: Review Article
Al-Mugdadi, S. F. H., Al-Zwaini, Y. K. H., & Sayyid, M. M. A. (2022) · University of Thi-Qar Journal of Science · doi:10.32792/utq/utjsci.v9i1.867 · Cited by 6 · see citing works
Virulence Factors and Molecular Identification of Candida Species Causing Candidemia in Honduras
Chávez, J. F., Ortíz, B., López, R., Muñoz, C., Aguilar, K., Laínez-Arteaga, I., Galindo, C., Rivera, L. E., Ballesteros‐Monrreal, M. G., Montes, K., et al. (2025) · Journal of Fungi · doi:10.3390/jof11070470 · Cited by 4 · see citing works
Lin, M., Huang, Y., Orihara, K., Chibana, H., Kajiwara, S., & Chen, X. (2023) · Journal of Fungi · doi:10.3390/jof10010016 · Cited by 4 · see citing works
Sobieh, S. S., Elshazly, R. G., Tawab, S., & Zaki, S. S. (2024) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-024-00504-x · Cited by 4 · see citing works
Current Updates on Pathogenesis, Systemic Therapy, and Treatment of Invasive Fungal Infections
Singh, S. K., & Pancholi, S. S. (2024) · Current Drug Targets · doi:10.2174/0113894501337502241015121015 · Cited by 4 · see citing works
De novo Nanopore Genome Sequencing of the Clinical Diutina catenulata Type-strain CBS565
Boden, S., Morio, F., Zhou, M., van den Ende, B. G., & Hagen, F. (2022) · Mycopathologia · doi:10.1007/s11046-022-00632-x · Cited by 4 · see citing works
A critical review on anticandidal properties of marine plants
Priyanka, K. R., & Rajaram, R. (2023) · Regional Studies in Marine Science · doi:10.1016/j.rsma.2023.103258 · Cited by 4 · see citing works
Antifungal and molecular analysis of gene expression caused by haloperidol in Candida spp.
de Oliveira, L. C., Moreira, L. E. A., Cabral, V. P. D. F., Rodrigues, D. S., Silveira, M. J. C. B., Ferreira, J. R. D. O., de Oliveira, A. C. M., Cavalcanti, B. C., Magalhães, I. L., Ferreira, J. R. D. O., et al. (2026) · Microbial Pathogenesis · doi:10.1016/j.micpath.2026.108343 · Cited by 4 · see citing works
Exploring Paenibacillus terrae B6a as a sustainable biocontrol agent for Fusarium proliferatum
Smith, E., Daniel, A. I., Smith, C., Fisher, S., Nkomo, M. A., Keyster, M., & Klein, A. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1547571 · Cited by 3 · see citing works
Rahbari, F. Z., Shams‐Ghahfarokhi, M., Baheiraei, N., & Razzaghi‐Abyaneh, M. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.107451 · Cited by 3 · see citing works
Tang, J., Cai, L., He, H., Li, X., Liang, S., Zhang, L., Xue, X., Xu, B., & Pan, W. (2025) · Medical Mycology · doi:10.1093/mmy/myaf087 · Cited by 3 · see citing works
Oliveira, M. C., da Silva, T. A., da Silva, J. J., Steiner‐Oliveira, C., Höfling, J. F., de Souza, A. C., & Boriollo, M. F. G. (2024) · Microbial Pathogenesis · doi:10.1016/j.micpath.2024.106948 · Cited by 3 · see citing works
Kouris, C., Mirea, S. I., Luminos, M. L., & Miron, V. D. (2024) · Microorganisms · doi:10.3390/microorganisms12102090 · Cited by 4 · see citing works
El-Enain, I. M. A., Abed, N. N., Helal, E. E.-H., Abdelkhalek, E. S., Suleiman, W. B., Safwat, N. A., & Yosri, M. (2023) · Recent Advances in Anti-Infective Drug Discovery · doi:10.2174/2772434418666230427165013 · Cited by 3 · see citing works
The Emergence of N. sativa L. as a Green Antifungal Agent
Pandey, R., Pandey, B., & Bhargava, A. (2024) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/0113895575282914240217060251 · Cited by 3 · see citing works
Martínez, O. I. C., Angulo-Ortíz, A., Patiño, G. S., Martínez, J. S., Soto, R., Rodolpho, J. M. D. A., de Godoy, K. F., Aníbal, F. D. F., & Fragelli, B. D. D. L. (2024) · Molecules · doi:10.3390/molecules29184417 · Cited by 3 · see citing works
Golipoor, M., Rafat, Z., Saberi, A., Roostaei, D., & Shabanpour, A.-M. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1477230 · Cited by 4 · see citing works
Candida auris as a pathogen that can cause emerging infectious disease: a literature review
Arthisari, N. N. N., Budayanti, N. N. S., & Tarini, N. M. A. (2023) · Intisari Sains Medis · doi:10.15562/ism.v14i1.1679 · Cited by 3 · see citing works
Morales-López, S. E., Ustate, K., Pedrozo, Z., & Torres, Y. (2023) · Biomédica · doi:10.7705/biomedica.6861 · Cited by 2 · see citing works
Kaczmarek, A., & Boguś, M. I. (2025) · Journal of Invertebrate Pathology · doi:10.1016/j.jip.2025.108328 · Cited by 2 · see citing works
Bègue, H., Ducreux, A., Paradis, T., Loiselet, A., Mourer, T., Lucchi, G., Kieffer‐Jaquinod, S., Couté, Y., Hube, B., Theodorou, I., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2573038 · Cited by 2 · see citing works
Dynamics of Virulence of Commensals: Preventive Phenotypical Mutability
Chepur, S. V., Nn, P., Sayganov, S. A., Chubar, O. V., Сергеевна, Б. Л., & Litvinenko, I. (2023) · Biology Bulletin Reviews · doi:10.1134/s207908642306004x · Cited by 2 · see citing works
Pathogenesis of fungal infections
Ruiz‐Moyano, S., Nevado, F. P., Rodríguez, A., Córdoba, M. D. G., Martı́n, A., & Córdoba, J. J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-818619-0.00124-6 · Cited by 2 · see citing works
Barbosa, P. F., Gonçalves, D. D. S., Ramos, L. S., de Mello, T. P., Braga-Silva, L. A., Pinto, M. R., Taborda, C. P., Branquinha, M. H., & dos Santos, A. L. S. (2024) · Infectious Disease Reports · doi:10.3390/idr16040043 · Cited by 2 · see citing works
Biofilm Formation in Candida Species
Elibe, M. I., & Innocent, N. E. (2024) · Springer eBooks · doi:10.1007/978-981-97-4909-6_9 · Cited by 2 · see citing works
Frequency and Distribution of Broncho-Alveolar Fungi in Lung Diseases in Martinique
Agossou, M., Inamo, J., Ahouansou, N., Dufeal, M., Provost, M., Badaran, E., Zouzou, A., Awanou, B., Dramé, M., & Desbois-Nogard, N. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12175480 · Cited by 2 · see citing works
El-Enain, I. M. A., Abed, N. N., Helal, E. E.-H., Abdelkhalek, E. S., & Suleiman, W. B. (2022) · Research Square · doi:10.21203/rs.3.rs-1730237/v1 · Cited by 2 · see citing works
da Silva, L. J., Rodrigues, D. S., Cabral, V. P. D. F., da Silva, C. R., Sá, L. G. D. A. V., Neto, J. B. D. A., Barbosa, A. D., Flaresso, A. A., da Rocha, S. N. C., Cavalcanti, B. C., et al. (2024) · Brazilian Journal of Microbiology · doi:10.1007/s42770-024-01498-5 · Cited by 2 · see citing works
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Özkaya, Y., Dışhan, A., Hızlısoy, H., Barel, M., Koskeroglu, K., Başar, M., & Gönülalan, Z. (2025) · International Journal of Dairy Technology · doi:10.1111/1471-0307.70000 · Cited by 1 · see citing works
Prado, A., Costa, P. D. S., Brito, R. D. O., Ferreira, D. G., Caris, G. A. Y., Negri, M., & Svidzinski, T. I. E. (2025) · Brazilian Journal of Microbiology · doi:10.1007/s42770-025-01662-5 · Cited by 1 · see citing works
Schatz, C. Y., Taverna, C. G., Refojo, N., Corach, D., Sala, A., & Caputo, M. (2025) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2025.117058 · Cited by 2 · see citing works
- Authors
- Mba, I. E., & Nweze, E. I.
- Affiliations
- University of Nigeria (NG)
- Corresponding author
- Nweze, Emeka Innocent
- Venue
- European Journal of Clinical Microbiology & Infectious Diseases
- Published
- 2020-05-06
- Volume
- 39
- Issue
- 10
- Pages
- 1797-1819
- ISSN
- 0934-9723 (ISSN-L)
- 1435-4373
- OpenAlex
- W3021920646
- Semantic Scholar
- 9a873a14a817c1928242b4ff3aa7bdb3341fc8f7
- Cited by
- 143
- References
- 230
- Citations by year
- 2026: 13 · 2025: 35 · 2024: 26 · 2023: 29 · 2022: 19 · 2021: 16 · 2020: 4 · 2019: 1
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Microbiology & Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Keywords
- Candida, fungal pathogenesis, virulence factors, candidiasis, morphological switching, biofilm formation, extracellular hydrolytic enzymes, metabolic flexibility, genome plasticity, pH adaptation, nutrient acquisition, adhesins, invasin, heat shock proteins, cytolytic proteins, phagocytosis evasion, immune evasion, antifungal resistance, stress response
- MeSH terms
- Antifungal Agents, Candida, Candidiasis, Humans, Drug Resistance, Fungal, Virulence Factors
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