Cited by 304Antifungal resistance and susceptibilityFungal and yeast genetics researchYeasts and Rust Fungi Studies

Adherence and biofilm formation of non-Candida albicans Candida species

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Silva, Sónia, Negri, Melyssa, Henriques, Mariana, Oliveira, Rosário, Williams, David W., Azeredo, Joana·2011·Trends in Microbiology

Abstract

Most cases of candidosis have been attributed to Candida albicans, but recently non-C. albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases and haemolysins). Although 'new'Candida species are emerging, there is still a lack of information about their pathogenicity. This review discusses recent advances in our knowledge of Candida glabrata, Candida parapsilosis and Candida tropicalis virulence factors, specifically those of adhesion and biofilm formation, which are key components in Candida pathogenicity.

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Crossref · 10.1016/j.tim.2011.02.003

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  • Candida glabrata biofilm maturation is characterized by production of the extracellular matrix.

    “the C. glabrata biofilm maturation is characterized by the production of the extracellular matrix [4,54].”

    From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [54]

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Authors
Silva, S., Negri, M., Henriques, M., Oliveira, R., Williams, D. W., & Azeredo, J.
Affiliations
  • Institute for Biotechnology and Bioengineering (PT)
  • Cardiff University (GB)
Corresponding author
Henriques, Mariana
Venue
Trends in Microbiology
Publisher
Elsevier BV
Published
2011-05
Volume
19
Issue
5
Pages
241-247
ISSN
0966-842X (ISSN-L)
OpenAlex
W2141740190
Cited by
304
References
78
Citations by year
2026: 12 · 2025: 18 · 2024: 23 · 2023: 19 · 2022: 19 · 2021: 22 · 2020: 24 · 2019: 21 · 2018: 22 · 2017: 27 · 2016: 25 · 2015: 23 · 2014: 16 · 2013: 14 · 2012: 15
FWCI
1.96
Type
journal article
Language
en
Open access
Locations
  • Trends in Microbiology (publishedVersion)
  • PubMed (publishedVersion)
  • RepositóriUM (Universidade do Minho) (submittedVersion, other-oa)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc-nd)
Funders
Fundação para a Ciência e a Tecnologia (SFRH/BD/28341/2006)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
Keywords
Candida glabrata, Candida parapsilosis, Candida tropicalis, adhesion, biofilm formation, virulence factors, candidiasis, host cell adhesion, hydrolytic enzymes
MeSH terms
Candida, Candidiasis, Cell Adhesion, Humans, Biofilms

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