Adherence and biofilm formation of non-Candida albicans Candida species
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Most cases of candidosis have been attributed to Candida albicans, but recently non-C. albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases and haemolysins). Although 'new'Candida species are emerging, there is still a lack of information about their pathogenicity. This review discusses recent advances in our knowledge of Candida glabrata, Candida parapsilosis and Candida tropicalis virulence factors, specifically those of adhesion and biofilm formation, which are key components in Candida pathogenicity.
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Candida glabrata biofilm maturation is characterized by production of the extracellular matrix.
“the C. glabrata biofilm maturation is characterized by the production of the extracellular matrix [4,54].”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [54]
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- Authors
- Silva, S., Negri, M., Henriques, M., Oliveira, R., Williams, D. W., & Azeredo, J.
- Affiliations
- Institute for Biotechnology and Bioengineering (PT)
- Cardiff University (GB)
- Corresponding author
- Henriques, Mariana
- Venue
- Trends in Microbiology
- Publisher
- Elsevier BV
- Published
- 2011-05
- Volume
- 19
- Issue
- 5
- Pages
- 241-247
- ISSN
- 0966-842X (ISSN-L)
- OpenAlex
- W2141740190
- Cited by
- 304
- References
- 78
- Citations by year
- 2026: 12 · 2025: 18 · 2024: 23 · 2023: 19 · 2022: 19 · 2021: 22 · 2020: 24 · 2019: 21 · 2018: 22 · 2017: 27 · 2016: 25 · 2015: 23 · 2014: 16 · 2013: 14 · 2012: 15
- FWCI
- 1.96
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Trends in Microbiology (publishedVersion)
- PubMed (publishedVersion)
- RepositóriUM (Universidade do Minho) (submittedVersion, other-oa)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc-nd)
- Funders
- Fundação para a Ciência e a Tecnologia (SFRH/BD/28341/2006)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Keywords
- Candida glabrata, Candida parapsilosis, Candida tropicalis, adhesion, biofilm formation, virulence factors, candidiasis, host cell adhesion, hydrolytic enzymes
- MeSH terms
- Candida, Candidiasis, Cell Adhesion, Humans, Biofilms
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