A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

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NeuN, a neuronal specific nuclear protein in vertebratesxs

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Satellite Cells and the Muscle Stem Cell Niche

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Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

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Reflecting on 25 years with MYC

Meyer, N., & Penn, L. Z. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2231 · Cited by 1,575

Positional Cloning of the Mouse Circadian Gene

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Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein

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The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

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AH RECEPTOR SIGNALING PATHWAYS

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The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

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E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

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The transcriptional control of hematopoiesis [see comments]

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Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

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The helix-loop-helix gene E2A is required for B cell formation

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The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence.

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Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins

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Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

Ben-David, Y., Giddens, E. B., Letwin, K., & Bernstein, A. (1991) · Genes & Development · doi:10.1101/gad.5.6.908 · Cited by 403

An Overview of MYC and Its Interactome

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TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

Liu, D., Black, B. L., & Derynck, R. (2001) · Genes & Development · doi:10.1101/gad.925901 · Cited by 399

BIN1 is a novel MYC–interacting protein with features of a tumour suppressor

Sakamuro, D., Elliott, K. J., Wechsler-Reya, R., & Prendergast, G. C. (1996) · Nature Genetics · doi:10.1038/ng0996-69 · Cited by 387

The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos.

Jiang, J., Kosman, D., Ip, Y. T., & Levine, M. (1991) · Genes & Development · doi:10.1101/gad.5.10.1881 · Cited by 365

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

Pongubala, J. M., Nagulapalli, S., Klemsz, M. J., McKercher, S. R., Maki, R. A., & Atchison, M. L. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.1.368 · Cited by 354

The runt domain identifies a new family of heterometric transcriptional regulators

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PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors

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Mutations in TCF4, Encoding a Class I Basic Helix-Loop-Helix Transcription Factor, Are Responsible for Pitt-Hopkins Syndrome, a Severe Epileptic Encephalopathy Associated with Autonomic Dysfunction

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The ets gene family

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Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages.

Beiman, M., Shilo, B. Z., & Volk, T. (1996) · Genes & Development · doi:10.1101/gad.10.23.2993 · Cited by 302

A thermodynamic scale for leucine zipper stability and dimerization specificity: e and g interhelical interactions.

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In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition.

Dolwick, K. M., Swanson, H. I., & Bradfield, C. A. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.18.8566 · Cited by 239

Establishment of the Mesoderm-Neuroectoderm Boundary in the Drosophila Embryo

Kosman, D., Ip, Y. T., Levine, M., & Arora, K. (1991) · Science · doi:10.1126/science.1925551 · Cited by 243

Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

Osborne, T. F., & Espenshade, P. J. (2009) · Genes & Development · doi:10.1101/gad.1854309 · Cited by 238

A Basic Helix-Loop-Helix–Leucine Zipper Transcription Complex in Yeast Functions in a Signaling Pathway from Mitochondria to the Nucleus

Jia, Y., Rothermel, B., Thornton, J., & Butow, R. A. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.3.1110 · Cited by 219

Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA‐1 and GATA‐2

Anguita, E., Hughes, J., Heyworth, C., Blobel, G. A., Wood, W. G., & Higgs, D. R. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600274 · Cited by 207

MicroRNAs, new effectors and regulators of NF‐κB

Boldin, M. P., & Baltimore, D. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01089.x · Cited by 199

Evolutionary conservation of a cell fate specification gene: the Hydra achaete-scute homolog has proneural activity in Drosophila

Grens, A., Mason, E., Marsh, J. L., & Bode, H. R. (1995) · Development · doi:10.1242/dev.121.12.4027 · Cited by 143

Genetic mechanisms of early neurogenesis inDrosophila melanogaster

Campos-Ortega, J. A. (1995) · Molecular Neurobiology · doi:10.1007/bf02740668 · Cited by 137

Rtg3p, a basic helix-loop-helix/leucine zipper protein that functions in mitochondrial-induced changes in gene expression, contains independent activation domains

Rothermel, B. A., Thornton, J. L., & Butow, R. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.32.19801 · Cited by 112

Mechanisms for Decreased Function of B Cells in Aged Mice and Humans

Frasca, D., Landin, A. M., Riley, R. L., & Blomberg, B. B. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.5.2741 · Cited by 97

PU.1 and an HLH family member contribute to the myeloid‐specific transcription of the Fc gamma RIIIA promoter.

Feinman, R., Qiu, W. Q., Pearse, R. N., Nikolajczyk, B. S., Sen, R., Sheffery, M., & Ravetch, J. V. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06696.x · Cited by 88

Interactions between dorsal and helix-loop-helix proteins initiate the differentiation of the embryonic mesoderm and neuroectoderm in Drosophila.

González-Crespo, S., & Levine, M. (1993) · Genes & Development · doi:10.1101/gad.7.9.1703 · Cited by 79

MicroRNAs miR-155 and miR-16 decrease AID and E47 in B cells from elderly individuals

Frasca, D., Diaz, A., Romero, M., Ferracci, F., & Blomberg, B. B. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1500520 · Cited by 69

Role Of The zerknüllt Gene In Dorsal-Ventral Pattern Formation In Drosophila

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Transcription Factor Pip Can Enhance DNA Binding by E47, Leading to Transcriptional Synergy Involving Multiple Protein Domains

Nagulapalli, S., & Atchison, M. L. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.8.4639 · Cited by 66

Involvement of Hydra achaete–scute gene CnASH in the differentiation pathway of sensory neurons in the tentacles

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A Screen for Gene Paralogies Delineating Evolutionary Branching Order of Early Metazoa

Erives, A., & Fritzsch, B. (2020) · G3 Genes|Genomes|Genetics · doi:10.1534/g3.119.400951 · Cited by 49

Mouse β-Globin DNA-Binding Protein B1 is Identical to a Proto-Oncogene, the Transcription Factor Spi-1 /PU.1, and is Restricted in Expression to Hematopoietic Cells and the Testis

Galson, D. L., Hensold, J. O., Bishop, T. R., Schalling, M., D'Andrea, A. D., Jones, C., Auron, P. E., & Housman, D. E. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.5.2929-2941.1993 · Cited by 45

OCT4 and SOX2 Work as Transcriptional Activators in Reprogramming Human Fibroblasts

Narayan, S., Bryant, G., Shah, S., Berrozpe, G., & Ptashne, M. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.07.071 · Cited by 43

PU.1 is a Component of a Multiprotein Complex Which Binds an Essential Site in the Murine Immunoglobulin λ2-4 Enhancer

Eisenbeis, C. F., Singh, H., & Storb, U. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.10.6452-6461.1993 · Cited by 38

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

Viner, C., Ishak, C. A., Johnson, J., Walker, N. J., Shi, H., Sjöberg-Herrera, M. K., Shen, S. Y., Lardo, S. M., Adams, D. J., Ferguson-Smith, A. C., et al. (2024) · Genome Biology · doi:10.1186/s13059-023-03070-0 · Cited by 30

Transcription Factor PU.1 Mediates Induction of c- fms in Vascular Smooth Muscle Cells: a Mechanism for Phenotypic Change to Phagocytic Cells

Inaba, T., Gotoda, T., Ishibashi, S., Harada, K., Ohsuga, J.-I., Ohashi, K., Yazaki, Y., & Yamada, N. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.5.2264 · Cited by 24

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

Viner, C., Ishak, C. A., Johnson, J., Walker, N. J., Shi, H., Sjöberg-Herrera, M. K., Shen, S. Y., Lardo, S. M., Adams, D. J., Ferguson-Smith, A. C., et al. (2016) · doi:10.1101/043794 · Cited by 18

T and Z , partial seed coat patterning genes in common bean, provide insight into the structure and protein interactions of a plant MBW complex

McClean, P. E., Roy, J., Colbert, C. L., Osborne, C., Lee, R., Miklas, P. N., & Osorno, J. M. (2024) · G3: Genes, Genomes, Genetics · doi:10.1093/g3journal/jkae184 · Cited by 13