On the role of volume transmission and receptor-receptor interactions in social behaviour: focus on central catecholamine and oxytocin neurons

Fuxe, Kjell; Borroto-Escuela, Dasiel O.; Romero-Fernandez, Wilber; Ciruela, Francisco; Manger, Paul; Leo, Guiseppina; Díaz-Cabiale, Zaida; Agnati, Luigi F.

doi:10.1016/j.brainres.2012.01.062

Cited by 81Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

On the role of volume transmission and receptor-receptor interactions in social behaviour: focus on central catecholamine and oxytocin neurons

Fuxe, Kjell, Borroto-Escuela, Dasiel O., Romero-Fernandez, Wilber, Ciruela, Francisco, Manger, Paul, Leo, Guiseppina, Díaz-Cabiale, Zaida, Agnati, Luigi F.·2012·Brain Research

DOI 10.1016/j.brainres.2012.01.062

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Abstract

This article is focused on understanding the mechanisms for the interactions between the central catecholamine (CA) and oxytocin (OXY) neurons and their relevance for brain function especially social behaviour in the field of pair bonding. Such a topic is analysed under two perspectives namely the intercellular communication modes between CA and OXT neurons and the molecular integrative mechanisms at the plasma membrane level between their respective decoding systems. As a matter of fact, recent observations strongly indicate a major role of volume transmission and receptor-receptor interactions in the CA/OXT neuron interplay in the brain control of social behaviour and pair bonding. This article is part of a Special Issue entitled: Brain Integration.

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Background
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Authors: Fuxe, K., Borroto-Escuela, D. O., Romero-Fernandez, W., Ciruela, F., Manger, P., Leo, G., Díaz-Cabiale, Z., & Agnati, L. F.
Affiliations: Universitat de Barcelona (ES)
University of the Witwatersrand (ZA)
Istituti di Ricovero e Cura a Carattere Scientifico (IT)
ORCID: Ciruela, Francisco
Manger, Paul
Venue: Brain Research
Publisher: Elsevier BV
Published: 2012-10
Volume: 1476
Pages: 119-131
ISSN: 0006-8993 (ISSN-L)
DOI: 10.1016/j.brainres.2012.01.062
OpenAlex: W1991632415
Cited by: 81
References: 101
Citations by year: 2026: 3 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 9 · 2021: 7 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 8 · 2016: 4 · 2015: 10 · 2014: 6 · 2013: 6 · 2012: 4
FWCI: 12.55
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Brain Research (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: volume transmission, receptor-receptor interactions, oxytocin neurons, social behavior, pair bonding, intercellular communication, plasma membrane signaling, brain integration
MeSH terms: Animals, Brain, Catecholamines, Cell Communication, Humans, Neurons, Oxytocin, Social Behavior

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On the role of volume transmission and receptor-receptor interactions in social behaviour: focus on central catecholamine and oxytocin neurons

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