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Reinforcement sensitivity, depression and anxiety: A meta-analysis and meta-analytic structural equation model
Abstract
Reinforcement Sensitivity Theory (RST) posits that individual differences in reward and punishment processing predict differences in cognition, behavior, and psychopathology. We performed a quantitative review of the relationships between reinforcement sensitivity, depression and anxiety, in two separate sets of analyses. First, we reviewed 204 studies that reported either correlations between reinforcement sensitivity and self-reported symptom severity or differences in reinforcement sensitivity between diagnosed and healthy participants, yielding 483 effect sizes. Both depression (Hedges' g = .99) and anxiety (g = 1.21) were found to be high on punishment sensitivity. Reward sensitivity negatively predicted only depressive disorders (g = -.21). More severe clinical states (e.g., acute vs remission) predicted larger effect sizes for depression but not anxiety. Next, we reviewed an additional 39 studies that reported correlations between reinforcement sensitivity and both depression and anxiety, yielding 156 effect sizes. We then performed meta-analytic structural equation modeling to simultaneously estimate all covariances and control for comorbidity. Again we found punishment sensitivity to predict depression (β = .37) and anxiety (β = .35), with reward sensitivity only predicting depression (β = -.07). The transdiagnostic role of punishment sensitivity and the discriminatory role of reward sensitivity support a hierarchical approach to RST and psychopathology.
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“Невосприимчивость к положительному подкреплению приводит к развитию симптома ангедонии.”
From Когнитивные механизмы дисфункционального принятия решений при психических расстройствах (2025) · cites this paper as Katz et al., 2020
In the citing paper
“Однако при клинической депрессии обостренная чувствительность к негативному подкреплению соседствует со сниженной чувствительностью к положительному подкреплению (Katz et al., 2020).”
From Когнитивные механизмы дисфункционального принятия решений при психических расстройствах (2025) · cites this paper as Katz et al., 2020
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Metadata
- Authors
- Katz, B. A., Matanky, K., Aviram, G., & Yovel, I.
- Affiliations
- Hebrew University of Jerusalem (IL)
- Corresponding author
- Katz, Benjamin A.
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2020-04
- Volume
- 77
- Pages
- 101842
- ISSN
- 0272-7358 (ISSN-L)
- OpenAlex
- W3009760869
- Cited by
- 109
- References
- 410
- Citations by year
- 2026: 18 · 2025: 20 · 2024: 15 · 2023: 16 · 2022: 16 · 2021: 14 · 2020: 9
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Israel Science Foundation (886/18)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- Reinforcement Sensitivity Theory, punishment sensitivity, reward sensitivity, depression, anxiety, psychopathology, transdiagnostic mechanisms, comorbidities, symptom severity, remission
- MeSH terms
- Latent Class Analysis, Anxiety, Depression, Humans, Punishment, Reward
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