Behavioral activation and inhibition systems and the severity and course of depression.
Abstract
Theorists have proposed that depression is associated with abnormalities in the behavioral activation (BAS) and behavioral inhibition (BIS) systems. In particular, depressed individuals are hypothesized to exhibit deficient BAS and overactive BIS functioning. Self-reported levels of BAS and BIS were examined in 62 depressed participants and 27 nondepressed controls. Clinical functioning was assessed at intake and at 8-month follow-up. Relative to nondepressed controls, depressed participants reported lower BAS levels and higher BIS levels. Within the depressed group, lower BAS levels were associated with greater concurrent depression severity and predicted worse 8-month outcome. Levels of both BIS and BAS showed considerable stability over time and clinical state. Overall, results suggest that BAS dysregulation exacerbates the presentation and course of depressive illness.
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Symptoms of emotional disorders reflect shared underlying factors, especially neuroticism, a stable tendency to experience negative affect.
“Findings from recent research suggest that the various symptoms of emotional disorders are in fact manifestations of common underlying factors. Such underlying factors include prominently the core temperamental dimension of neuroticism, an enduring tendency to experience negative affect (Brown, Chorpita, & Barlow, 1998; Gershuny & Sher, 1998; Kasch, Rottenberg, Arnow, & Gotlib, 2002; Watson, Clark”
From The role of negative affectivity and negative reactivity to emotions in predicting outcomes in the unified protocol for the transdiagnostic treatment of emotional disorders (2012) · cites this paper as Kasch, Rottenberg, Arnow, & Gotlib, 2002
Neuroticism/negative affect and extraversion/positive affect have been closely related to Gray's constructs of behavioral inhibition and behavioral activation, and these terms are often used interchangeably as the most stable measures of temperament.
“N/NA and E/PA have been closely related to Gray’s (1987) constructs of BI and BA, respectively [24-26], and these terms are often used interchangeably as the most stable measures of temperament [8,15,26,27].”
From Negative and positive affect regulation in a transdiagnostic internet-based protocol for emotional disorders: Randomized controlled trial (2021) · cites this paper as [25]
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- Authors
- Kasch, K. L., Rottenberg, J., Arnow, B. A., & Gotlib, I. H.
- Affiliations
- Stanford University (US)
- Stanford Medicine (US)
- Venue
- Journal of Abnormal Psychology
- Published
- 2002-11
- Volume
- 111
- Issue
- 4
- Pages
- 589-597
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- OpenAlex
- W2112996418
- Cited by
- 551
- References
- 49
- Citations by year
- 2026: 10 · 2025: 20 · 2024: 14 · 2023: 26 · 2022: 22 · 2021: 26 · 2020: 23 · 2019: 17 · 2018: 25 · 2017: 31 · 2016: 25 · 2015: 28 · 2014: 37 · 2013: 29 · 2012: 40
- FWCI
- 11.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
- Funders
- National Institute of Mental Health (MH59259, R01MH059259)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- behavioral activation system, behavioral inhibition system, depression, depression severity, course of depression, trait impulsivity, treatment outcome prediction, trait stability
- MeSH terms
- Adolescent, Adult, Analysis of Variance, Behavior, Cross-Sectional Studies, Depressive Disorder, Female, Follow-Up Studies, Humans, Inhibition, Psychological, Longitudinal Studies, Male, Middle Aged, Psychiatric Status Rating Scales, Surveys and Questionnaires, Self Disclosure, Severity of Illness Index
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