Positive Psychological Well-Being and Cardiovascular Disease
Open accessAbstract
Facets of positive psychological well-being, such as optimism, have been identified as positive health assets because they are prospectively associated with the 7 metrics of cardiovascular health (CVH) and improved outcomes related to cardiovascular disease. Connections between psychological well-being and cardiovascular conditions may be mediated through biological, behavioral, and psychosocial pathways. Individual-level interventions, such as mindfulness-based programs and positive psychological interventions, have shown promise for modifying psychological well-being. Further, workplaces are using well-being-focused interventions to promote employee CVH, and these interventions represent a potential model for expanding psychological well-being programs to communities and societies. Given the relevance of psychological well-being to promoting CVH, this review outlines clinical recommendations to assess and promote well-being in encounters with patients. Finally, a research agenda is proposed. Additional prospective observational studies are needed to understand mechanisms underlying the connection between psychological well-being and cardiovascular outcomes. Moreover, rigorous intervention trials are needed to assess whether psychological well-being-promoting programs can improve cardiovascular outcomes.
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Findings are relatively consistent across studies and evident for multiple facets of positive psychological health, although effect sizes are modest.
“Findings are relatively consistent across studies and evident for multiple facets of positive psychological health, although effect sizes are modest. 54,141-143”
From Psychological Health, Well-Being, and the Mind-Heart-Body Connection: A Scientific Statement From the American Heart Association (2021) · cites this paper as [54]
In “Psychological Health and Cardiovascular Disease” (page unavailable), the paper reports generally consistent associations between several facets of well-being and reduced cardiovascular risk, including a pooled relative risk of 0.83 for purpose in life. It also says findings for other facets are “not fully consistent” and that recent large studies of positive affect found null results. The claim’s broad characterization of consistency is therefore stronger than the source warrants; the cited cardiovascular-risk discussion does not characterize its effect sizes as modest. (LLM, conf=0.83)
Experimental — accuracy not yet measuredPPWB is associated with higher psychological functioning, lower incidence of chronic diseases, lower risk of cardiovascular events, and improved health behaviors.
“PPWB is associated with higher psychological functioning, 16 lower incidence of chronic diseases (e.g., gastrointestinal disease, arthritis), 18 lower risk of cardiovascular events, 19 and improved health behaviors such as regular exercise, restful sleep, and a decreased sedentary behavior. 1”
From Positive psychological well-being in women with obesity: A scoping review of qualitative and quantitative primary research (2022) · cites this paper as [19]
The Behavioral Pathways section reports that higher psychological well-being is associated with a greater likelihood of regular exercise. The paper mentions optimal sleep as a possible restorative process, but the passages do not establish an association with restful sleep or decreased sedentary behavior. The other outcomes in the sentence have separate citations; this verdict addresses the health-behavior claim attached to this source. (LLM, conf=0.86)
Experimental — accuracy not yet measuredCardiovascular researchers have identified that optimism, positive psychological constructs, and subjective well-being are linked to significantly better cardiovascular outcomes, decreased rehospitalization and reduced risk of mortality.
“Cardiovascular researchers have identified that optimism, positive psychological constructs, and subjective well‐being are linked to significantly better cardiovascular outcomes, decreased rehospitalization and reduced risk of mortality. 19 , 21 , 64 , 65 , 66”
From Positive psychological well-being in women with obesity: A scoping review of qualitative and quantitative primary research (2022) · cites this paper as [19]
The ‘Psychological Health and Cardiovascular Disease’ section (page not provided) reports associations between optimism and other facets of well-being and lower cardiovascular risk, including lower heart disease and stroke mortality in a cohort of older women. It does not report decreased rehospitalization, and its mortality evidence is specific to cardiovascular outcomes rather than mortality generally. (LLM, conf=0.88)
Experimental — accuracy not yet measuredSome, but not all, other studies have found relationships between positive psychological factors and healthy immune response or lower levels of inflammation.
“Some, but not all, other studies have similarly found relationships between positive psychological factors and healthy immune response or lower levels of inflammation. 54,133-135”
From Psychological Health, Well-Being, and the Mind-Heart-Body Connection: A Scientific Statement From the American Heart Association (2021) · cites this paper as [54]
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Allostatic overload in patients with essential hypertension
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- Authors
- Kubzansky, L. D., Huffman, J. C., Boehm, J. K., Hernandez, R., Kim, E. S., Koga, H. K., Feig, E. H., Lloyd-Jones, D. M., Seligman, M. E. P., & Labarthe, D. R.
- Affiliations
- Harvard University (US)
- Chapman University (US)
- University of Pennsylvania (US)
- Northwestern University (US)
- Corresponding author
- Labarthe, Darwin R.
- ORCID
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 72
- Issue
- 12
- Pages
- 1382-1396
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC6289282
- OpenAlex
- W2889747628
- Cited by
- 429
- References
- 139
- Citations by year
- 2026: 48 · 2025: 67 · 2024: 68 · 2023: 69 · 2022: 63 · 2021: 46 · 2020: 35 · 2019: 31 · 2018: 2
- FWCI
- 5.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Chapman University Digital Commons (Chapman University) (submittedVersion)
- Funders
- American Diabetes Association (1‐17‐ICTS‐099)
- National Institutes of Health (1-17-ICTS-099)
- National Institute on Aging (K99AG055696)
- National Heart, Lung, and Blood Institute (R01HL113272, R01HL133149, K01HL130712)
- National Institute of Diabetes and Digestive and Kidney Diseases (R21DK109313)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
- Social Sciences › Psychology › Applied Psychology › Optimism, Hope, and Well-being
- Keywords
- positive psychological well-being, cardiovascular disease, cardiovascular health metrics, optimism, mindfulness-based interventions, positive psychology interventions, workplace well-being interventions, psychosocial pathways, biological pathways, behavioral pathways, cardiovascular outcomes
- MeSH terms
- Optimism, Cardiovascular Diseases, Health Promotion, Humans, Mental Health, Occupational Health Services, Social Environment, Stress, Psychological, Health Behavior, Mindfulness
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