Moody microbiome: Challenges and chances

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

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Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

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The ecology of the microbiome: Networks, competition, and stability

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Estimating the true global burden of mental illness

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Altered fecal microbiota composition in patients with major depressive disorder

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Animal models of neuropsychiatric disorders

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Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

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Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

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The interplay between the intestinal microbiota and the brain

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The central nervous system and the gut microbiome

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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

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Psychobiotics: A novel class of psychotropic

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A mega-analysis of genome-wide association studies for major depressive disorder

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Correlation between the human fecal microbiota and depression

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Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice

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Gender Bias in Autoimmunity Is Influenced by Microbiota

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Bacterial infection causes stress-induced memory dysfunction in mice

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The host shapes the gut microbiota via fecal microRNA

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Sex-specific transcriptional signatures in human depression

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A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood

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Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress

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Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

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Gut Microbiota Diversity and Human Diseases: Should We Reintroduce Key Predators in Our Ecosystem?

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Neuroimmune mechanisms of depression

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Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock

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Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder

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Beneficial psychological effects of a probiotic formulation ( <i>Lactobacillus helveticus</i> R0052 and <i>Bifidobacterium longum</i> R0175) in healthy human volunteers

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Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition

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Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: a randomized clinical trial

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Microbiota and host determinants of behavioural phenotype in maternally separated mice

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Effect of probiotics on depression: a systematic review and meta-analysis of randomized controlled trials

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The history of the tetracyclines

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Microbial Metabolic Networks at the Mucus Layer Lead to Diet-Independent Butyrate and Vitamin B 12 Production by Intestinal Symbionts

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Mitochondrial Dysfunction and Psychiatric Disorders

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Comparative assessment of human and farm animal faecal microbiota using real-time quantitative PCR

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Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiety: A Randomised Double-blind Placebo-controlled Trial

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<i> <scp>B</scp> ifidobacteria </i> exert strain‐specific effects on stress‐related behavior and physiology in <scp>BALB</scp> /c mice

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Altered gut microbiota profile in patients with generalized anxiety disorder

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Genetic and environmental control of host-gut microbiota interactions

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Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

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Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects

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Nutrient cross-feeding in the microbial world

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A double-blind, randomized, placebo-controlled trial of <i>Lactobacillus helveticus</i> and <i>Bifidobacterium longum</i> for the symptoms of depression

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Prevotella and Klebsiella proportions in fecal microbial communities are potential characteristic parameters for patients with major depressive disorder

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Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

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The gut microbiome composition associates with bipolar disorder and illness severity

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Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks

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Similar Fecal Microbiota Signatures in Patients With Diarrhea-Predominant Irritable Bowel Syndrome and Patients With Depression

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Sex differences in gut microbiota in patients with major depressive disorder

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Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat

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Analyses of the Microbial Diversity across the Human Microbiome

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Antidepressants, antimicrobials or both? Gut microbiota dysbiosis in depression and possible implications of the antimicrobial effects of antidepressant drugs for antidepressant effectiveness

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A step ahead: Exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode

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Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis

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Inflammatory Bowel Diseases Phenotype, C. difficile and NOD2 Genotype Are Associated with Shifts in Human Ileum Associated Microbial Composition

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Interaction Between Atypical Antipsychotics and the Gut Microbiome in a Bipolar Disease Cohort

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Possible role of the gut microbiota–brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model

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Minocycline as adjunctive therapy for patients with unipolar psychotic depression: An open-label study

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Microbiome Dynamics in a Shrimp Grow-out Pond with Possible Outbreak of Acute Hepatopancreatic Necrosis Disease

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Novel therapeutic targets in depression: Minocycline as a candidate treatment

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Comparative metaproteomics analysis shows altered fecal microbiota signatures in patients with major depressive disorder

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High-fat diet induces depression-like behaviour in mice associated with changes in microbiome, neuropeptide Y, and brain metabolome

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Microbiome: Should we diversify from diversity?

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Intestinal Microbiota as Modulators of the Immune System and Neuroimmune System: Impact on the Host Health and Homeostasis

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Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model

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Metagenomic Surveys of Gut Microbiota

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RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder

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Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour

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Dual Transcriptomic Profiling of Host and Microbiota during Health and Disease in Pediatric Asthma

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Genome composition and phylogeny of microbes predict their co-occurrence in the environment

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NetCooperate: a network-based tool for inferring host-microbe and microbe-microbe cooperation

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MetaMIS: a metagenomic microbial interaction simulator based on microbial community profiles

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Mouse strain affects behavioral and neuroendocrine stress responses following administration of probiotic Lactobacillus rhamnosus JB-1 or traditional antidepressant fluoxetine

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A combination of probiotics and magnesium orotate attenuate depression in a small SSRI resistant cohort: an intestinal anti-inflammatory response is suggested

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MMinte: an application for predicting metabolic interactions among the microbial species in a community

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Identification of sex-specific urinary biomarkers for major depressive disorder by combined application of NMR- and GC–MS-based metabonomics

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Effects of gut microbiota disturbance induced in early life on the expression of extrasynaptic GABA-A receptor α5 and δ subunits in the hippocampus of adult rats

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Bacterial translocation affects intracellular neuroinflammatory pathways in a depression-like model in rats

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Nitrated meat products are associated with mania in humans and altered behavior and brain gene expression in rats

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Hexacyclopeptides secreted by an endophytic fungus Fusarium solani N06 act as crosstalk molecules in Narcissus tazetta

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Altered Carbohydrates Allocation by Associated Bacteria-fungi Interactions in a Bark Beetle-microbe Symbiosis

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Targeting microbiota-mitochondria inter-talk: Microbiota control mitochondria metabolism.

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Lost in Translation: The Gut Microbiota in Psychiatric Illness

Anglin, R., Surette, M. G., Moayyedi, P., & Berčík, P. (2015) · The Canadian Journal of Psychiatry · doi:10.1177/070674371506001007 · Cited by 24 · see citing works

A Mesocosm of Lactobacillus johnsonii , Bifidobacterium longum , and Escherichia coli in the Mouse Gut

Denou, E., Rezzonico, E., Panoff, J.-M., Arigoni, F., & Brüssow, H. (2009) · DNA and Cell Biology · doi:10.1089/dna.2009.0873 · Cited by 23 · see citing works

Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature

Remes, O., Mendes, J. F., & Templeton, P. (2021) · Brain Sciences · doi:10.3390/brainsci11121633 · Cited by 482 · see citing works

Exploration of microbiota targets for major depressive disorder and mood related traits

Chung, Y.-C. E., Chen, H., Chou, H. L., Chen, I., Lee, M., Chuang, L.-C., Liu, Y.-W., Lu, M., Chen, C.-H., Wu, C., et al. (2019) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2019.01.016 · Cited by 192 · see citing works

Stress and the gut microbiota-brain axis

Molina‐Torres, G., Rodríguez-Arrastia, M. J., Román, P., Sánchez‐Labraca, N., & Cardona, D. (2019) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000478 · Cited by 186 · see citing works

Gut microbiome patterns depending on children’s psychosocial stress: Reports versus biomarkers

Michels, N., de Wiele, T. V., Fouhy, F., O’Mahony, S. M., Clarke, G. A., & Keane, J. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.05.024 · Cited by 115 · see citing works

The role of the gut-brain axis in depression: endocrine, neural, and immune pathways

Makris, A. P., Karianaki, M., Tsamis, K. I., & Paschou, S. Α. (2020) · HORMONES · doi:10.1007/s42000-020-00236-4 · Cited by 120 · see citing works

Probiotics and prebiotics: focus on psychiatric disorders – a systematic review

Barbosa, R. S. D., & Vieira‐Coelho, M. A. (2019) · Nutrition Reviews · doi:10.1093/nutrit/nuz080 · Cited by 93 · see citing works

Antibiotics and mental health: the good, the bad and the ugly

Dinan, K., & Dinan, T. (2022) · Journal of Internal Medicine · doi:10.1111/joim.13543 · Cited by 69 · see citing works

Neuroinflammation, Microbiota-Gut-Brain Axis, and Depression: The Vicious Circle

Reyes-Martínez, S., Segura-Real, L., Gómez-García, A. P., Tesoro-Cruz, E., Constantino-Jonapa, L. A., Amedei, A., & Aguirre‐García, M. M. (2023) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2203065 · Cited by 76 · see citing works

Targeting the Microbiota in Pharmacology of Psychiatric Disorders

Pascale, A., Marchesi, N., Govoni, S., & Barbieri, A. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104856 · Cited by 67 · see citing works

Shotgun metagenomics reveals both taxonomic and tryptophan pathway differences of gut microbiota in bipolar disorder with current major depressive episode patients

Lai, W., Zhao, J., Xu, S., Deng, W.-F., Xu, D., Wang, M., He, F.-S., Liu, Y., Guo, Y., Ye, S.-W., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.09.010 · Cited by 59 · see citing works

10th Anniversary of the European Association for Predictive, Preventive and Personalised (3P) Medicine - EPMA World Congress Supplement 2020

Golubnitschaja, O., Topolčan, O., Kučera, R., Costigliola, V., EPMA, Akopyan, M., Akulov, S. N., Alexandrova, O., Alonso, A., Andrews, R. J., et al. (2020) · The EPMA Journal · doi:10.1007/s13167-020-00206-1 · Cited by 56 · see citing works

Gut microbiome in adolescent depression

Thapa, S., Sheu, J. C., Venkatachalam, A., Runge, J. K., Luna, R. A., & Calarge, C. A. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.05.107 · Cited by 48 · see citing works

Mood and microbes: a comprehensive review of intestinal microbiota’s impact on depression

Luqman, A., He, M., Hassan, A., Ullah, M., Zhang, L., Khan, M. R., Din, A. U., Ullah, K., Wang, W. J., & Wang, G. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1295766 · Cited by 38 · see citing works

Identification of intestinal and fecal microbial biomarkers using a porcine social stress model

Nguyen, T. Q., Martínez-Álvaro, M., Lima, J., Auffret, M., Rutherford, K. M. D., Simm, G., Dewhurst, R., Baima, E. T., & Roehe, R. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1197371 · Cited by 32 · see citing works

Gut microbiome and metabolic pathways linked to sleep quality

Seong, H. J., Baek, Y., Lee, S., & Jin, H. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1418773 · Cited by 33 · see citing works

The Potential Effects of Radiation on the Gut-Brain Axis

Jones, C. B., Davis, C. M., & Sfanos, K. S. (2020) · Radiation Research · doi:10.1667/rr15493.1 · Cited by 27 · see citing works

Dysbiosis and depression: A study of gut microbiota alterations and functional pathways in antidepressant-naïve mood disorder patients

Lin, S.-K. K., Chen, H., Chen, I., Hsu, C.-D., Huang, M., Liu, C., Wu, S., Chen, P., Chen, C.-H., & Kuo, P. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03521-1 · Cited by 27 · see citing works

Exploration of the relationship between gut microbiota and fecal microRNAs in patients with major depressive disorder

Chen, H., Chung, Y.-C. E., Chen, H., Liu, Y.-W., Chen, I., Lu, M., Hsiao, F. S., Chen, C.-H., Huang, M., Shih, W., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-24773-7 · Cited by 25 · see citing works

The effects of Lactobacillus plantarum PS128 in patients with major depressive disorder: an eight-week double-blind, placebo-controlled study

Lin, S.-K. K., Kuo, P., Hsu, C., Chiu, Y.-H., & Chen, C.-H. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.104210 · Cited by 24 · see citing works

Exploring the human gut microbiota targets in relation to the use of contemporary antidepressants

Lin, S.-K. K., Chen, H., Chen, C.-H., Chen, I., Lu, M., Hsu, C., Chiu, Y.-H., Wang, T.-Y., Chen, H., Chung, Y.-C. E., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.10.016 · Cited by 21 · see citing works

Cardiac vagal activity is associated with gut-microbiome patterns in women—An exploratory pilot study

Mörkl, S., Oberascher, A., Tatschl, J. M., Lackner, S., Bastiaanssen, T. F. S., Butler, M., Moser, M., Frühwirth, M., Mangge, H., Cryan, J. F., et al. (2022) · Dialogues in Clinical Neuroscience · doi:10.1080/19585969.2022.2128697 · Cited by 18 · see citing works

Gut-Brain Axis: Probiotic,<i>Bacillus subtilis</i>, Prevents Aggression via the Modification of the Central Serotonergic System

Cheng, H.-W., Jiang, S., & Hu, J. (2019) · Oral Health by Using Probiotic Products · doi:10.5772/intechopen.86775 · Cited by 17 · see citing works

The Effect of Adjunctive Probiotics on Markers of Inflammation and Oxidative Stress in Bipolar Disorder: A Double-blind, Randomized, Controlled Trial

Sabouri, S., Esmailzadeh, M., Sadeghinejad, A., Shahrbabaki, M. E., Asadikaram, G., & Nikvarz, N. (2022) · Journal of Psychiatric Practice · doi:10.1097/pra.0000000000000660 · Cited by 17 · see citing works

Molecular Biomarkers for Pediatric Depressive Disorders: A Narrative Review

Lee, J., Chi, S., & Lee, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221810051 · Cited by 12 · see citing works

Embryonic Exposure to Tryptophan Yields Bullying Victimization via Reprogramming the Microbiota-Gut-Brain Axis in a Chicken Model

Huang, X., Hu, J., Peng, H., & Cheng, H. W. (2022) · Nutrients · doi:10.3390/nu14030661 · Cited by 12 · see citing works

Role of gut microbiota in the GBR12909 model of mania-like behavior in mice

de Miranda, A. S., Vieira, É. L. M., Bastos, J. D. R., Ferreira, R. N., Nicoli, J. R., Teixeira, M. M., Vieira, L. Q., Moreira, F. A., & Teixeira, A. L. (2020) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2020.577292 · Cited by 10 · see citing works

Heart rate variability, daily cortisol indices and their association with psychometric characteristics and gut microbiota composition in an Italian community sample

Ravenda, S., Mancabelli, L., Gambetta, S., Barbetti, M., Turroni, F., Carnevali, L., Ventura, M., & Sgoifo, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-93137-8 · Cited by 9 · see citing works

Glycoconjugates of Gram-negative bacteria and parasitic protozoa – are they similar in orchestrating the innate immune response?

Karaś, M. A., Turska-Szewczuk, A., Janczarek, M., & Szuster‐Ciesielska, A. (2019) · Innate Immunity · doi:10.1177/1753425918821168 · Cited by 8 · see citing works

An updated systematic review and appraisal of the pathophysiologic mechanisms of probiotics in alleviating depression

Sulaiman, N. N. Y., Nizam, N. B. M., Noor, N. A. M., Lim, S. M., Ramasamy, K., Alabsi, A. M., & Fareez, I. M. (2025) · Nutritional Neuroscience · doi:10.1080/1028415x.2025.2531357 · Cited by 6 · see citing works

The Role of the Gut Microbiome in Bipolar Disorder and its Common Medical Comorbidities

Jones, G. H., Pinjari, O. F., Vecera, C. M., Smith, K., Barrera, A., & Machado‐Vieira, R. (2023) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2023.101078 · Cited by 5 · see citing works

Antibiomania

Marković, T., Todorović, A., Stojković, M., Popović, S., Baskić, D., & Matic, S. D. (2025) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000002089 · Cited by 3 · see citing works

Hierarchy of human needs in the main character of beauty is a wound by Eka Kurniawan

Siska, S. (2021) · COMMICAST · doi:10.12928/commicast.v2i1.2734 · Cited by 3 · see citing works

Bugs to debug? The exploration of gut microbiome in human health and diseases

Ni, Y. (2019) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2019.01.017 · Cited by 2 · see citing works

The microbiota-gut-brain axis and bipolar disorder

Gomes‐da‐Costa, S., Salagre, E., Camino, S., Vázquez, G. H., & Grande, I. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819182-8.00023-5 · Cited by 1 · see citing works

Intergenerational and early life associations of the gut microbiome and stress-related symptomatology among Black American mothers and children

McKenna, B. G., Dunlop, A. L., Corwin, E. J., Smith, A. K., Venkateswaran, S., & Brennan, P. A. (2023) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2023.100651 · Cited by 1 · see citing works

Metabolic Pathways Underlying Neuropsychiatric Disorders and Obesity

Martins, L. B., Maurício, S. F., Ferreira, A. V. M., & Teixeira, A. L. (2020) · Springer eBooks · doi:10.1007/978-3-030-53370-0_30 · Cited by 1 · see citing works

11th International Congress on Psychopharmacology & 7th International Symposium on Child and Adolescent Psychopharmacology

(2019) · Psychiatry and Clinical Psychopharmacology · doi:10.1080/24750573.2019.1606883 · Cited by 1 · see citing works

The Trend of Fermented Foods

Wang, S. S. (2018) · Annals of Advanced Biomedical Sciences · doi:10.23880/aabsc-16000106

Microbiome and Vocalization Biomarkers of Infant Distress, Maternal Depression and Parenting Styles

Ligezka, A. N., Lynch, B. A., Saliba, M. T., Corral-Frias, M. P., Johnson, S., Chen, J., Allen, S. V., Frank, J. M., Voort, J. L. V., Croarkin, P. E., et al. (2026) · Chronic Stress · doi:10.1177/24705470261425120

Gut Microbiota Modulation in CNS Disorders: Therapeutic Strategies and Implications for Drug Efficacy

Ahmed, L. A., & Al‐Massri, K. F. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06192-1

Water is the only byproduct from this caprolactam process

(2002) · Focus on Catalysts · doi:10.1016/s1351-4180(02)00638-4

Microbiota–Gut–Brain Axis as a Therapeutic Nexus: Multimodal Probiotic, Antidepressant, and Nutritional Strategies

Lv, J., Xu, J., Lv, S., Zheng, Q., Chen, Y., & Wang, Q. (2026) · Microorganisms · doi:10.3390/microorganisms14102384

Gut Microbiota Dysbiosis and Depression: Pathological Mechanisms and the Therapeutic Potential of Probiotic Interventions

Wang, Y. (2025) · Theoretical and Natural Science · doi:10.54254/2753-8818/2025.ld26074

Probiotics for the treatment of depression and its comorbidities: A systemic review

Gao, J., Zhao, N., Cheng, Y., Lei, W., Wang, Y., Liu, X., Zheng, N., Shao, L., Chen, X., Sun, Y., et al. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1167116 · Cited by 75 · see citing works

Antidepressive Mechanisms of Probiotics and Their Therapeutic Potential

Yong, S. J., Tong, T., Chew, J., & Lim, W. L. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01361 · Cited by 217 · see citing works