Cited by 97Neuroendocrine regulation and behaviorNeurogenesis and neuroplasticity mechanismsAnimal Behavior and Reproduction

Flexibility and adaptation of the neural substrate that supports maternal behavior in mammals

Olazábal, Daniel E., Pereira, Mariana, Agrati, Daniella, Ferreira, Annabel, Fleming, Alison S., González-Mariscal, Gabriela, Lévy, Frederic, Lucion, Aldo B. +3 more·2013·Neuroscience & Biobehavioral Reviews

Abstract

Maternal behavior is species-specific and expressed under different physiological conditions, and contexts. It is the result of neural processes that support different forms (e.g. postpartum, cycling sensitized and spontaneous maternal behavior) and modalities of mother-offspring interaction (e.g. maternal interaction with altricial/precocious young; selective/non-selective bond). To understand how the brain adapts to and regulates maternal behavior in different species, and physiological and social conditions we propose new neural models to explain different forms of maternal expression (e.g. sensitized and spontaneous maternal behavior) and the behavioral changes that occur across the postpartum period. We emphasize the changing role of the medial preoptic area in the neural circuitry that supports maternal behavior and the cortical regulation and adjustment of ongoing behavioral performance. Finally, we discuss how our accumulated knowledge about the psychobiology of mothering in animal models supports the validity of animal studies to guide our understanding of human mothering and to improve human welfare and health.

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Crossref · 10.1016/j.neubiorev.2013.04.004

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Authors
Olazábal, D. E., Pereira, M., Agrati, D., Ferreira, A., Fleming, A. S., González-Mariscal, G., Lévy, F., Lucion, A. B., Morrell, J. I., Numan, M., & Uriarte, N.
Affiliations
  • Universidad de la República de Uruguay (UY)
  • Rutgers, The State University of New Jersey (US)
  • University of Toronto (CA)
  • Universidade Federal do Rio Grande do Sul (BR)
  • Boston College (US)
Corresponding author
Olazábal, Daniel E.
Venue
Neuroscience & Biobehavioral Reviews
Publisher
Elsevier BV
Published
2013-09
Volume
37
Issue
8
Pages
1875-1892
ISSN
0149-7634 (ISSN-L)
OpenAlex
W2059598844
Cited by
97
References
229
Citations by year
2026: 5 · 2025: 6 · 2024: 5 · 2023: 6 · 2022: 7 · 2021: 8 · 2020: 7 · 2019: 5 · 2018: 8 · 2017: 10 · 2016: 6 · 2015: 12 · 2014: 10 · 2013: 2
FWCI
1.31
Type
journal article
Language
en
Open access
closed
Locations
  • Neuroscience & Biobehavioral Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
Funders
  • the Comisión Sectorial de Investigación Científica (CSIC, UdelaR)
  • the French Embassy
  • the International Brain Research Organization (IBRO)
  • Programme for the Development of Basic Sciences (PEDECIBA, Uruguay)
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
Keywords
maternal behavior, neural correlates, medial preoptic area, postpartum period, mother-offspring interactions, human welfare
MeSH terms
Adaptation, Physiological, Animals, Female, Humans, Mammals, Maternal Behavior, Motivation, Preoptic Area, Postpartum Period

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