The DOI matches its Crossref record; 96 of the 97 references it cites were found in a registry or an index.
A convergent functional architecture of the insula emerges across imaging modalities
Open accessAbstract
Empirical evidence increasingly supports the hypothesis that patterns of intrinsic functional connectivity (iFC) are sculpted by a history of evoked coactivation within distinct neuronal networks. This, together with evidence of strong correspondence among the networks defined by iFC and those delineated using a variety of other neuroimaging techniques, suggests a fundamental brain architecture detectable across multiple functional and structural imaging modalities. Here, we leverage this insight to examine the functional organization of the human insula. We parcellated the insula on the basis of three distinct neuroimaging modalities - task-evoked coactivation, intrinsic (i.e., task-independent) functional connectivity, and gray matter structural covariance. Clustering of these three different covariance-based measures revealed a convergent elemental organization of the insula that likely reflects a fundamental brain architecture governing both brain structure and function at multiple spatial scales. While not constrained to be hierarchical, our parcellation revealed a pseudo-hierarchical, multiscale organization that was consistent with previous clustering and meta-analytic studies of the insula. Finally, meta-analytic examination of the cognitive and behavioral domains associated with each of the insular clusters obtained elucidated the broad functional dissociations likely underlying the topography observed. To facilitate future investigations of insula function across healthy and pathological states, the insular parcels have been made freely available for download via http://fcon_1000.projects.nitrc.org, along with the analytic scripts used to perform the parcellations.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“we used a validated three-cluster parcellation scheme to obtain a valid anterior insula mask76.”
From Randomized clinical trial shows no substantial modulation of empathy-related neural activation by intranasal oxytocin in autism (2021) · cites this paper as [76]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Jenkinson, M., Bannister, P., Brady, M., & Smith, S. (2002) · NeuroImage · doi:10.1006/nimg.2002.1132 · Cited by 11,888
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
Thomas Yeo, B. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zöllei, L., Polimeni, J. R., et al. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00338.2011 · Cited by 9,182
Dissociable intrinsic connectivity networks for salience processing and executive control
Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5587-06.2007 · Cited by 7,426
The organization of the human cerebellum estimated by intrinsic functional connectivity
Buckner, R. L., Krienen, F. M., Castellanos, A., Diaz, J. C., & Yeo, B. T. T. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00339.2011 · Cited by 7,304
A global optimisation method for robust affine registration of brain images
Jenkinson, M., & Smith, S. M. (2001) · Medical Image Analysis · doi:10.1016/s1361-8415(01)00036-6 · Cited by 7,018
How do you feel — now? The anterior insula and human awareness
(Bud) Craig, A. D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2555 · Cited by 6,657 · cited 4×
“…belied by its seclusion within the depths of the Sylvian fissure, the insula is now recognized as a nexus of sensory, somatic, interoceptive, cognitive and emotional processing, the integration of which may provide the neural substrate for human phenomenological experience (Craig, 2009a,b, 2011).”
InfluentialCorrespondence of the brain's functional architecture during activation and rest
Smith, S. M., Fox, P. T., Miller, K. L., Glahn, D. C., Fox, P. M., Mackay, C. E., Filippini, N., Watkins, K. E., Toro, R., Laird, A. R., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905267106 · Cited by 5,150
Self-citationA Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains
Good, C. D., Johnsrude, I. S., Ashburner, J., Henson, R. N. A., Friston, K. J., & Frackowiak, R. S. J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0786 · Cited by 4,561
Mapping the structural core of human cerebral cortex
Hagmann, P., Cammoun, L., Gigandet, X., Meuli, R., Honey, C. J., Wedeen, V. J., & Sporns, O. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060159 · Cited by 4,173
Large-scale automated synthesis of human functional neuroimaging data.
Yarkoni, T., Poldrack, R. A., Nichols, T. E., Van Essen, D. C., & Wager, T. D. (2011) · Nature Methods · doi:10.1038/nmeth.1635 · Cited by 3,686 · cited 1×
“Indeed, more comprehensive and detailed text-based meta-analytic methods, such as those implemented in NeuroSynth (Yarkoni et al., 2011), may be required to derive a thorough and representative mapping of insular functional domains.”
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406 · cited 1×
“…and Overy, 2006; Small, 2010; Small et al., 2003), vestibulo-proprioceptive processing, interoception (including satiety and craving; e.g., Critchley et al., 2004; Naqvi and Bechara, 2009), somesthesis (including nociception; e.g., Brooks et al., 2005; Starr et al., 2009), somatic control…”
Predicting human resting-state functional connectivity from structural connectivity
Honey, C. J., Sporns, O., Cammoun, L., Gigandet, X., Thiran, J. P., Meuli, R., & Hagmann, P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811168106 · Cited by 3,307
Toward discovery science of human brain function
Biswal, B. B., Mennes, M., Zuo, X.-N., Gohel, S., Kelly, C., Smith, S. M., Beckmann, C. F., Adelstein, J. S., Buckner, R. L., Colcombe, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911855107 · Cited by 2,970
Self-citationCircular analysis in systems neuroscience: the dangers of double dipping
Kriegeskorte, N., Simmons, W. K., Bellgowan, P. S. F., & Baker, C. I. (2009) · Nature Neuroscience · doi:10.1038/nn.2303 · Cited by 2,696
Distinct brain networks for adaptive and stable task control in humans
Dosenbach, N. U. F., Fair, D. A., Miezin, F. M., Cohen, A. L., Wenger, K. K., Dosenbach, R. A. T., Fox, M. D., Snyder, A. Z., Vincent, J. L., Raichle, M. E., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704320104 · Cited by 2,632
Common regions of the human frontal lobe recruited by diverse cognitive demands
Duncan, J., & Owen, A. M. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01633-7 · Cited by 2,498
Murphy, K., Birn, R. M., Handwerker, D. A., Jones, T. B., & Bandettini, P. A. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.09.036 · Cited by 2,387
Neurodegenerative Diseases Target Large-Scale Human Brain Networks
Seeley, W. W., Crawford, R. K., Zhou, J., Miller, B. L., & Greicius, M. D. (2009) · Neuron · doi:10.1016/j.neuron.2009.03.024 · Cited by 2,350
Both of Us Disgusted in My Insula
Wicker, B., Keysers, C., Plailly, J., Royet, J.-P., Gallese, V., & Rizzolatti, G. (2003) · Neuron · doi:10.1016/s0896-6273(03)00679-2 · Cited by 2,185
Monti, S., Tamayo, P., Mesirov, J., & Golub, T. (2003) · Machine Learning · doi:10.1023/a:1023949509487 · Cited by 2,116
A dual-networks architecture of top-down control
Dosenbach, N. U. F., Fair, D. A., Cohen, A. L., Schlaggar, B. L., & Petersen, S. E. (2008) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2008.01.001 · Cited by 1,931
Time–frequency dynamics of resting-state brain connectivity measured with fMRI
Chang, C., & Glover, G. H. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.12.011 · Cited by 1,808
Intrinsic functional architecture in the anaesthetized monkey brain
Vincent, J. L., Patel, G. H., Fox, M. D., Snyder, A. Z., Baker, J. T., Van Essen, D. C., Zempel, J. M., Snyder, L. H., Corbetta, M., & Raichle, M. E. (2007) · Nature · doi:10.1038/nature05758 · Cited by 1,786
Circuitry and functional aspects of the insular lobe in primates including humans
AUGUSTINE, J. (1996) · Brain Research Reviews · doi:10.1016/s0165-0173(96)00011-2 · Cited by 1,776
A whole brain fMRI atlas generated via spatially constrained spectral clustering
Craddock, R. C., James, G. A., Holtzheimer, P. E., Hu, X. P., & Mayberg, H. S. (2012) · Human Brain Mapping · doi:10.1002/hbm.21333 · Cited by 1,636
Comparing clusterings—an information based distance
Meilă, M. (2006) · Journal of Multivariate Analysis · doi:10.1016/j.jmva.2006.11.013 · Cited by 1,597
Puzzlingly High Correlations in fMRI Studies of Emotion, Personality, and Social Cognition
Vul, E., Harris, C., Winkielman, P., & Pashler, H. (2009) · Perspectives on Psychological Science · doi:10.1111/j.1745-6924.2009.01125.x · Cited by 1,475 · cited 2×
“, 2011) the use of pre-defined ROIs allows researchers to test hypotheses concerning differential localization or timing of stimulus or task-evoked responses without “double-dipping” (Kriegeskorte et al., 2009; Vul et al., 2009).”
Paulus, M. P., & Stein, M. B. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.042 · Cited by 1,325
Kurth, F., Zilles, K., Fox, P. T., Laird, A. R., & Eickhoff, S. B. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0255-z · Cited by 1,293
A common role of insula in feelings, empathy and uncertainty
Singer, T., Critchley, H. D., & Preuschoff, K. (2009) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2009.05.001 · Cited by 1,270
Behavioral interpretations of intrinsic connectivity networks
Laird, A. R., Fox, P. M., Eickhoff, S. B., Turner, J. A., Ray, K. L., McKay, D. R., Glahn, D. C., Beckmann, C. F., Smith, S. M., & Fox, P. T. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00077 · Cited by 1,023
Insula of the old world monkey. III: Efferent cortical output and comments on function
Mesulam, M. ‐., & Mufson, E. J. (1982) · Journal of Comparative Neurology · doi:10.1002/cne.902120104 · Cited by 1,013
The hidden island of addiction: the insula
Naqvi, N. H., & Bechara, A. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2008.09.009 · Cited by 833 · cited 4×
“Given the implication of the insula across several clinical and psychiatric disorders, including autism and addiction (Di Martino et al., 2009a; Naqvi and Bechara, 2009), delineating these connectivity-based functional building blocks of the insula will inform investigations of the role of this…”
InfluentialDissociation of Neural Representation of Intensity and Affective Valuation in Human Gustation
Small, D. M., Gregory, M. D., Mak, Y. E., Gitelman, D. R., Mesulam, M. M., & Parrish, T. B. (2003) · Neuron · doi:10.1016/s0896-6273(03)00467-7 · Cited by 812
Functional connectivity of the insula in the resting brain
Cauda, F., D'Agata, F., Sacco, K., Duca, S., Geminiani, G., & Vercelli, A. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2010.11.049 · Cited by 793
Functional connectivity of the human amygdala using resting state fMRI
Roy, A. K., Shehzad, Z., Margulies, D. S., Kelly, A. M. C., Uddin, L. Q., Gotimer, K., Biswal, B. B., Castellanos, F. X., & Milham, M. P. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.11.030 · Cited by 749
Self-citationPaulus, M. P., Rogalsky, C., Simmons, A., Feinstein, J. S., & Stein, M. B. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00251-9 · Cited by 745
Three systems of insular functional connectivity identified with cluster analysis
Deen, B., Pitskel, N. B., & Pelphrey, K. A. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq186 · Cited by 716
White matter maturation reshapes structural connectivity in the late developing human brain
Hagmann, P., Sporns, O., Madan, N., Cammoun, L., Pienaar, R., Wedeen, V. J., Meuli, R., Thiran, J.-P., & Grant, P. E. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1009073107 · Cited by 700
Electrophysiological correlates of the brain's intrinsic large-scale functional architecture
He, B. J., Snyder, A. Z., Zempel, J. M., Smyth, M. D., & Raichle, M. E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807010105 · Cited by 670
Mesulam, M. M., & Mufson, E. J. (1982) · The Journal of Comparative Neurology · doi:10.1002/cne.902120102 · Cited by 660
Significance of the insula for the evolution of human awareness of feelings from the body
(Bud) Craig, A. D. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.05990.x · Cited by 646
The neurocircuitry of impaired insight in drug addiction
Goldstein, R. Z., Craig, A. D. (., Bechara, A., Garavan, H., Childress, A. R., Paulus, M. P., & Volkow, N. D. (2009) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2009.06.004 · Cited by 641
A Random Walks View of Spectral Segmentation.
Meilă, M., & Shi, J. (2001) · Cited by 628
Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response
Medford, N., & Critchley, H. D. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0265-x · Cited by 627
Forebrain emotional asymmetry: a neuroanatomical basis?
Craig, A. D. (. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.10.005 · Cited by 626
Structural covariance in the human cortex
Mechelli, A., Friston, K. J., Frackowiak, R. S., & Price, C. J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.0357-05.2005 · Cited by 606
THE INSULA: FURTHER OBSERVATIONS ON ITS FUNCTION
PENFIELD, W., & FAULK, M. E. (1955) · Brain · doi:10.1093/brain/78.4.445 · Cited by 606
Martino, A. D., Ross, K. V., Uddin, L. Q., Sklar, A. B., Castellanos, F. X., & Milham, M. P. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.022 · Cited by 597
Self-citationEmpathy for positive and negative emotions in the gustatory cortex
Jabbi, M., Swart, M., & Keysers, C. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.10.032 · Cited by 590
Defining functional areas in individual human brains using resting functional connectivity MRI
Cohen, A. L., Fair, D. A., Dosenbach, N. U. F., Miezin, F. M., Dierker, D., Van Essen, D. C., Schlaggar, B. L., & Petersen, S. E. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.01.066 · Cited by 582
Insula of the old world monkey. II: Afferent cortical input and comments on the claustrum
Mufson, E. J., & Mesulam, M. ‐. (1982) · Journal of Comparative Neurology · doi:10.1002/cne.902120103 · Cited by 559
Mars, R. B., Sallet, J., Schuffelgen, U., Jbabdi, S., Toni, I., & Rushworth, M. F. S. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhr268 · Cited by 520
Dissociable neural systems for recognizing emotions
Adolphs, R., Tranel, D., & Damásio, A. R. (2003) · Brain and Cognition · doi:10.1016/s0278-2626(03)00009-5 · Cited by 501
Emotional moments across time: a possible neural basis for time perception in the anterior insula
Craig, A. D. (. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2009.0008 · Cited by 499 · cited 4×
“…belied by its seclusion within the depths of the Sylvian fissure, the insula is now recognized as a nexus of sensory, somatic, interoceptive, cognitive and emotional processing, the integration of which may provide the neural substrate for human phenomenological experience (Craig, 2009a,b, 2011).”
InfluentialMusic and mirror neurons: from motion to ’e’motion
Molnar-Szakacs, I., & Overy, K. (2006) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsl029 · Cited by 497
Mars, R. B., Jbabdi, S., Sallet, J., O’Reilly, J. X., Croxson, P. L., Olivier, E., Noonan, M. P., Bergmann, C., Mitchell, A. S., Baxter, M. G., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.5102-10.2011 · Cited by 486
Role of the anterior insula in task-level control and focal attention
Nelson, S. M., Dosenbach, N. U. F., Cohen, A. L., Wheeler, M. E., Schlaggar, B. L., & Petersen, S. E. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0260-2 · Cited by 435
The anterior insula in autism: Under-connected and under-examined
Uddin, L. Q., & Menon, V. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.06.002 · Cited by 432
Normalized Cut Group Clustering of Resting-State fMRI Data
van den Heuvel, M. P., Mandl, R. C. W., & Pol, H. E. H. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002001 · Cited by 418
The Spinothalamic System Targets Motor and Sensory Areas in the Cerebral Cortex of Monkeys
Dum, R. P., Levinthal, D. J., & Strick, P. L. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3398-09.2009 · Cited by 408
At the heart of the ventral attention system: The right anterior insula
Eckert, M. A., Menon, V., Walczak, A., Ahlstrom, J., Denslow, S., Horwitz, A., & Dubno, J. R. (2009) · Human Brain Mapping · doi:10.1002/hbm.20688 · Cited by 406
Network-level structural covariance in the developing brain
Zielinski, B. A., Gennatas, E. D., Zhou, J., & Seeley, W. W. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003109107 · Cited by 405
Laird, A., Lancaster, J., & Fox, P. (2007) · Neuroinformatics · doi:10.1385/ni:3:1:065 · Cited by 379
Functional Coactivation Map of the Human Brain
Toro, R., Fox, P. T., & Paus, T. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn014 · Cited by 378
Self-citationBrooks, J. C. W., Zambreanu, L., Godinez, A., Craig, A. D. (., & Tracey, I. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.041 · Cited by 355
A Parcellation Scheme for Human Left Lateral Parietal Cortex
Nelson, S. M., Cohen, A. L., Power, J. D., Wig, G. S., Miezin, F. M., Wheeler, M. E., Velanova, K., Donaldson, D. I., Phillips, J. S., Schlaggar, B. L., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.05.025 · Cited by 348
Multi-level bootstrap analysis of stable clusters in resting-state fMRI
Bellec, P., Rosa‐Neto, P., Lyttelton, O. C., Benali, H., & Evans, A. C. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.02.082 · Cited by 343
Self-citationProgressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula
Nestor, P. J. (2003) · Brain · doi:10.1093/brain/awg240 · Cited by 326
The Dynamical Balance of the Brain at Rest
Deco, G., & Corbetta, M. (2010) · The Neuroscientist · doi:10.1177/1073858409354384 · Cited by 323
Strokes restricted to the insular cortex
Cereda, C., Ghika, J., Maeder, P., & Bogousslavsky, J. (2002) · Neurology · doi:10.1212/01.wnl.0000038905.75660.bd · Cited by 302
Taste representation in the human insula
Small, D. M. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0266-9 · Cited by 300
Roles of the Insular Cortex in the Modulation of Pain: Insights from Brain Lesions
Starr, C. J., Sawaki, L. A., Wittenberg, G. F., Burdette, J. H., Oshiro, Y., de Quevedo, A. S., & Coghill, R. C. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5173-08.2009 · Cited by 297
Cytoarchitecture and Probabilistic Maps of the Human Posterior Insular Cortex
Kurth, F., Eickhoff, S. B., Schleicher, A., Hömke, L., Zilles, K., & Amunts, K. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp208 · Cited by 256
The Embodiment of Emotional Feelings in the Brain
Harrison, N. A., Gray, M. A., Gianaros, P. J., & Critchley, H. D. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1725-10.2010 · Cited by 250
Functional organization of the human anterior insular cortex
Mutschler, I., Wieckhorst, B., Kowalevski, S., Derix, J., Wentlandt, J., Schulze‐Bonhage, A., & Ball, T. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.03.101 · Cited by 238
Network anticorrelations, global regression, and phase‐shifted soft tissue correction
Anderson, J. S., Druzgal, T. J., Lopez-Larson, M. P., Jeong, E., Desai, K., & Yurgelun-Todd, D. A. (2010) · Human Brain Mapping · doi:10.1002/hbm.21079 · Cited by 235
The Insula and Cerebrogenic Sudden Death
Cheung, R. T. F., & Hachinski, V. (2000) · Archives of Neurology · doi:10.1001/archneur.57.12.1685 · Cited by 219
Clinical effects of insular damage in humans
Ibañez, A., Gleichgerrcht, E., & Manes, F. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0256-y · Cited by 217
Kelly, C. A. M., Uddin, L. Q., Shehzad, Z. E., Margulies, D. S., Castellanos, F. X., Milham, M. P., & Petrides, M. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07279.x · Cited by 213
Self-citationDi Martino, A., Shehzad, Z., Kelly, C., Roy, A. K., Gee, D. G., Uddin, L. Q., Gotimer, K., Klein, D. F., Castellanos, F. X., & Milham, M. P. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08121894 · Cited by 213
Self-citationIntrinsic functional architecture predicts electrically evoked responses in the human brain
Keller, C. J., Bickel, S., Entz, L., Ulbert, I., Milham, M. P., Kelly, C. A. M., & Mehta, A. D. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019750108 · Cited by 206
Self-citationDevlin, J. T., & Poldrack, R. A. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.09.055 · Cited by 195
Ackermann, H., & Riecker, A. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0257-x · Cited by 191
Left insula activation: A marker for language attainment in bilinguals
Chee, M. W. L., Soon, C. S., Lee, H. L., & Pallier, C. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403703101 · Cited by 182
Shelley, B. P., & Trimble, M. (2004) · The World Journal of Biological Psychiatry · doi:10.1080/15622970410029933 · Cited by 172
The Extrinsic and Intrinsic Functional Architectures of the Human Brain Are Not Equivalent
Mennes, M., Kelly, C. A. M., Colcombe, S. J., Castellanos, F. X., & Milham, M. P. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhs010 · Cited by 167
Self-citationAnterior insula degeneration in frontotemporal dementia
Seeley, W. W. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0263-z · Cited by 162
Functional localization within the prefrontal cortex: missing the forest for the trees?
Wilson, C. R. E., Gaffan, D., Browning, P. G. F., & Baxter, M. G. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.08.001 · Cited by 126
Involvement of Insula and Cingulate Cortices in Control and Suppression of Natural Urges
Lerner, A., Bagic, A., Hanakawa, T., Boudreau, E. A., Pagan, F., Mari, Z., Bara-Jimenez, W., Aksu, M., Sato, S., Murphy, D. L., et al. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn074 · Cited by 112
Kang, J., Wang, L., Yan, C., Wang, J., Liang, X., & He, Y. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.03.033 · Cited by 111
Group analyses of connectivity-based cortical parcellation using repeated k-means clustering
Nanetti, L., Cerliani, L., Gazzola, V., Renken, R. J., & Keysers, C. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.06.014 · Cited by 111
The Insula of Reil Revisited: Multiarchitectonic Organization in Macaque Monkeys
Gallay, D., Gallay, M., Jeanmonod, D., Rouiller, E., & Morel, A. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr104 · Cited by 60
Steinbrink, C., Ackermann, H., Lachmann, T., & Riecker, A. (2008) · Human Brain Mapping · doi:10.1002/hbm.20674 · Cited by 48
Stability analysis in K ‐means clustering
Steinley, D. (2007) · British Journal of Mathematical and Statistical Psychology · doi:10.1348/000711007x184849 · Cited by 47
Flagged first, then by citations
1 of the 97 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Strehl, 2002, Cluster ensembles — a knowledge reuse framework for combining multiple partitions, J. Mach. Learn. Res., 3, 583
Cited by
Sorted by citations
The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture
Fan, L., Li, H., Zhuo, J., Zhang, Y., Wang, J., Chen, L., Yang, Z., Chu, C., Xie, S., Laird, A. R., et al. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw157 · Cited by 3,083
Salience processing and insular cortical function and dysfunction
Uddin, L. Q. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3857 · Cited by 2,083
Network attributes for segregation and integration in the human brain
Sporns, O. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.11.015 · Cited by 1,067
Imaging structural co-variance between human brain regions
Alexander-Bloch, A., Giedd, J. N., & Bullmore, E. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3465 · Cited by 1,064
Behavioral interpretations of intrinsic connectivity networks
Laird, A. R., Fox, P. M., Eickhoff, S. B., Turner, J. A., Ray, K. L., McKay, D. R., Glahn, D. C., Beckmann, C. F., Smith, S. M., & Fox, P. T. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00077 · Cited by 1,023
Metadata
- Authors
- Kelly, C., Toro, R., Di Martino, A., Cox, C. L., Bellec, P., Castellanos, F. X., & Milham, M. P.
- Affiliations
- NYU Langone Health (US)
- Centre National de la Recherche Scientifique (FR)
- Institut Universitaire de Gériatrie de Montréal (CA)
- Nathan Kline Institute for Psychiatric Research (US)
- Corresponding author
- Kelly, Clare
- Milham, Michael P.
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2012-07
- Volume
- 61
- Issue
- 4
- Pages
- 1129-1142
- ISSN
- 1053-8119 (ISSN-L)
- PMC
- PMC3376229
- OpenAlex
- W2066720008
- Cited by
- 374
- References
- 97
- Citations by year
- 2026: 15 · 2025: 14 · 2024: 15 · 2023: 23 · 2022: 20 · 2021: 25 · 2020: 34 · 2019: 25 · 2018: 29 · 2017: 38 · 2016: 36 · 2015: 31 · 2014: 36 · 2013: 26 · 2012: 6
- FWCI
- 16.20
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- HAL (submittedVersion)
- Funders
- National Institute on Drug Abuse (R03DA024775, 2T32DA007254-16A2, R01DA016979)
- National Institute of Mental Health (R01MH083246, R01MH081218, K23MH087770)
- National Institute of Child Health and Human Development (R01HD065282)
- Leon Levy Foundation
- Autism Speaks
- Stavros Niarchos Foundation
- Alicia Koplowitz Foundation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- insula, functional parcellation, intrinsic functional connectivity
- MeSH terms
- Cerebral Cortex, Humans, Image Interpretation, Computer-Assisted, Neural Pathways, Cluster Analysis, Neuroimaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
