The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.
Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging
Open accessAbstract
Autism is a neurodevelopmental disorder characterized by abnormal reciprocal social interactions, communication deficits, and repetitive behaviors with restricted interests. Autism-relevant phenotypes in the inbred mouse strain BTBR T+tf/J (BTBR) offer translational tools to discover biological mechanisms underlying unusual mouse behaviors analogous to symptoms of autism. Two of the most consistent findings with BTBR are lack of sociability as measured by the three-chamber social approach task and increased amount of time engaged in self-grooming in an empty cage. Here we evaluated BTBR as compared to two typical inbred strains with high sociability and low self-grooming, C57BL/6J (B6) and FVB/AntJ (FVB), on both the automated three-chambered social approach task and repetitive self-grooming assays. Brains from the behaviorally tested mice were analyzed using magnetic resonance imaging and diffusion tensor imaging to investigate potential neuroanatomical abnormalities throughout the brain; specifically, to discover neuroanatomical mechanisms which could explain the autism-relevant behavioral abnormalities. Significant differences in volume and white matter microstructure were detected in multiple anatomical regions throughout the brain of BTBR compared to B6 and FVB. Further, significant correlations were found between behavioral measures and areas of the brain known to be associated with those behaviors. For example, striatal volume was strongly correlated to time spent in self-grooming across strains. Our findings suggest that neuropathology exists in BTBR beyond the previously reported white matter abnormalities in the corpus callosum and hippocampal commissure and that these brain differences may be related to the behavioral abnormalities seen in BTBR.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The most striking neuroanatomical features of BTBR mice are the absence of corpus callosum and the extremely reduced hippocampal commissure, observed by diffusion tensor tractography and on histologic preparations [87, 96, 367].”
From Autism spectrum disorder: neuropathology and animal models (2017) · cites this paper as [96]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Diagnostic and Statistical Manual of Mental Disorders.
Widiger, T. A. (2000) · Oxford University Press eBooks · doi:10.1037/10518-009 · Cited by 19,766
Thresholding of statistical maps in functional neuroimaging using the false discovery rate
Genovese, C. R., Lazar, N. A., & Nichols, T. (2002) · NeuroImage · doi:10.1006/nimg.2001.1037 · Cited by 4,923
The basis of anisotropic water diffusion in the nervous system—A technical review.
Beaulieu, C. (2002) · NMR in Biomedicine · doi:10.1002/nbm.782 · Cited by 4,628
Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space
Collins, D. L., Neelin, P., Peters, T. M., & Evans, A. C. (1994) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199403000-00005 · Cited by 3,431 · cited 2×
“All registrations were performed using a combination of the mni_autoreg tools (Collins et al., 1994) and ANTS (Avants et al.”
MethodThe Social Brain: Neural Basis of Social Knowledge
Adolphs, R. (2009) · Annual Review of Psychology · doi:10.1146/annurev.psych.60.110707.163514 · Cited by 1,827
Amaral, D. G., Schumann, C. M., & Nordahl, C. W. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2007.12.005 · Cited by 1,492
Behavioural phenotyping assays for mouse models of autism
Silverman, J. L., Yang, M., Lord, C., & Crawley, J. N. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2851 · Cited by 1,462
Self-citationAutism and Abnormal Development of Brain Connectivity: Figure 1.
Belmonte, M. K., Allen, G., Beckel-Mitchener, A., Boulanger, L. M., Carper, R. A., & Webb, S. J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3340-04.2004 · Cited by 1,217
Agenesis of the corpus callosum: Genetic, developmental and functional aspects of connectivity
Paul, L. K., Brown, W. S., Adolphs, R., Tyszka, J. M., Richards, L. J., Mukherjee, P., & Sherr, E. H. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2107 · Cited by 830
Autism‐like behavioral phenotypes in BTBR T+tf/J mice
McFarlane, H. G., Kusek, G. K., Yang, M., Phoenix, J. L., Bolivar, V. J., & Crawley, J. N. (2008) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2007.00330.x · Cited by 812
Self-citationMouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains
MOY, S., NADLER, J., YOUNG, N., PEREZ, A., HOLLOWAY, L., BARBARO, R., BARBARO, J., WILSON, L., THREADGILL, D., & LAUDER, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.07.030 · Cited by 776
The optimal template effect in hippocampus studies of diseased populations
Avants, B. B., Yushkevich, P., Pluta, J., Minkoff, D., Korczykowski, M., Detre, J., & Gee, J. C. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.062 · Cited by 640
Automated Three‐Chambered Social Approach Task for Mice
Yang, M., Silverman, J. L., & Crawley, J. N. (2011) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0826s56 · Cited by 598
Self-citationSimple Behavioral Assessment of Mouse Olfaction
Yang, M., & Crawley, J. N. (2009) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0824s48 · Cited by 573
Self-citationHOW THE BRAIN PROCESSES SOCIAL INFORMATION: Searching for the Social Brain
Insel, T. R., & Fernald, R. D. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144148 · Cited by 556
Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism
Scattoni, M. L., Gandhy, S. U., Ricceri, L., & Crawley, J. N. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003067 · Cited by 550
Self-citationMouse Behavioral Assays Relevant to the Symptoms of Autism*
Crawley, J. N. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00096.x · Cited by 541 · cited 1×
“1A) using methods previously described (Chadman et al., 2008; Crawley, 2007; McFarlane et al., 2008; Moy et al., 2008; Silverman et al., 2010a, 2010b, 2011; Yang et al., 2009, 2011a, 2011b).”
MethodSelf-citationDorr, A. E., Lerch, J. P., Spring, S., Kabani, N. J., & Henkelman, R. M. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.03.037 · Cited by 539
Self-citationStanfield, A. C., McIntosh, A. M., Spencer, M. D., Philip, R., Gaur, S., & Lawrie, S. M. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2007.05.006 · Cited by 524
Cellular Mechanisms of Social Attachment
Young, L. J., Lim, M. M., Gingrich, B., & Insel, T. R. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1691 · Cited by 523
Diffusion tensor imaging in autism spectrum disorder: a review
Travers, B. G., Adluru, N., Ennis, C., Tromp, D. P. M., Destiche, D., Doran, S., Bigler, E. D., Lange, N., Lainhart, J. E., & Alexander, A. L. (2012) · Autism Research · doi:10.1002/aur.1243 · Cited by 450
Silverman, J. L., Tolu, S. S., Barkan, C. L., & Crawley, J. N. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.201 · Cited by 438
Self-citationSillitoe, R. V., & Joyner, A. L. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123237 · Cited by 400
An MRI study of the basal ganglia in autism
Sears, L. L., Vest, C., Mohamed, S., Bailey, J., Ranson, B. J., & Piven, J. (1999) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(99)00020-2 · Cited by 364
Scattoni, M. L., Ricceri, L., & Crawley, J. N. (2010) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2010.00623.x · Cited by 340
Self-citationDosage-dependent phenotypes in models of 16p11.2 lesions found in autism
Horev, G., Ellegood, J., Lerch, J. P., Son, Y.-E. E., Muthuswamy, L., Vogel, H., Krieger, A. M., Buja, A., Henkelman, R. M., Wigler, M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114042108 · Cited by 330
Self-citationReduced Caudate Nucleus Volume in Obsessive-compulsive Disorder
Robinson, D. G. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950170067009 · Cited by 320
A developmental study of the structural integrity of white matter in autism
Keller, T. A., Kana, R. K., & Just, M. A. (2007) · Neuroreport · doi:10.1097/01.wnr.0000239965.21685.99 · Cited by 302
Maze training in mice induces MRI-detectable brain shape changes specific to the type of learning
Lerch, J. P., Yiu, A. P., Martinez-Canabal, A., Pekar, T., Bohbot, V. D., Frankland, P. W., Henkelman, R. M., Josselyn, S. A., & Sled, J. G. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2010.09.086 · Cited by 300
Self-citationMinimal aberrant behavioral phenotypes of neuroligin‐3 R451C knockin mice
Chadman, K. K., Gong, S., Scattoni, M. L., Boltuck, S. E., Gandhy, S. U., Heintz, N., & Crawley, J. N. (2008) · Autism Research · doi:10.1002/aur.22 · Cited by 292
Self-citationThe neurobiology of repetitive behavior: …and men
Langen, M., Durston, S., Kas, M. J., van Engeland, H., & Staal, W. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.02.005 · Cited by 280
A Meta-Analysis of the Corpus Callosum in Autism
Frazier, T. W., & Hardan, A. Y. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.022 · Cited by 267
Assessing autism-like behavior in mice: Variations in social interactions among inbred strains
BOLIVAR, V, WALTERS, S., & PHOENIX, J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.09.007 · Cited by 264
Silverman, J. L., Smith, D. G., Rizzo, S. J. S., Karras, M. N., Turner, S. M., Tolu, S. S., Bryce, D. K., Smith, D. L., Fonseca, K., Ring, R. H., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003501 · Cited by 251
Self-citationDiffusion tensor imaging of the developing mouse brain
Mori, S., Itoh, R., Zhang, J., Kaufmann, W. E., van Zijl, P. C. M., Solaiyappan, M., & Yarowsky, P. (2001) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1155 · Cited by 236
The neurobiology of repetitive behavior: Of mice…
Langen, M., Kas, M. J., Staal, W., van Engeland, H., & Durston, S. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.02.004 · Cited by 233
Sociability and motor functions in Shank1 mutant mice
Silverman, J. L., Turner, S. M., Barkan, C. L., Tolu, S. S., Saxena, R., Hung, A. Y., Sheng, M., & Crawley, J. N. (2011) · Brain Research · doi:10.1016/j.brainres.2010.09.026 · Cited by 218
Self-citationWahlsten, D., Metten, P., & Crabbe, J. C. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02354-0 · Cited by 206
Amodeo, D. A., Jones, J. H., Sweeney, J. A., & Ragozzino, M. E. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.10.032 · Cited by 200
Structural and functional magnetic resonance imaging of autism spectrum disorders
Stigler, K. A., McDonald, B. C., Anand, A., Saykin, A. J., & McDougle, C. J. (2011) · Brain Research · doi:10.1016/j.brainres.2010.11.076 · Cited by 197
Development of a mouse test for repetitive, restricted behaviors: Relevance to autism
Moy, S. S., Nadler, J. J., Poe, M. D., Nonneman, R. J., Young, N. B., Koller, B. H., Crawley, J. N., Duncan, G. E., & Bodfish, J. W. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.10.029 · Cited by 195
Self-citationRadua, J., Via, E., Catani, M., & Mataix-Cols, D. (2011) · Psychological Medicine · doi:10.1017/s0033291710002187 · Cited by 183
Spring, S., Lerch, J. P., & Henkelman, R. M. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.02.023 · Cited by 182
Self-citationVerhoeven, J. S., Cock, P. D., Lagae, L. G., & Sunaert, S. G. (2009) · Neuroradiology · doi:10.1007/s00234-009-0583-y · Cited by 180
The neurobiology of social recognition, approach, and avoidance
Young, L. J. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01268-9 · Cited by 177
Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism
Pearson, B. L., Pobbe, R. L. H., Defensor, E. B., Oasay, L., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00659.x · Cited by 171
Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism
Wöhr, M., Roullet, F. I., & Crawley, J. N. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2010.00582.x · Cited by 169 · cited 2×
“…et al., 2007; Chadman, 2011; Defensor et al., 2011; McFarlane et al., 2008; Moy et al., 2007; Pearson et al., 2011; Pobbe et al., 2010, 2011; Roullet et al., 2011; Scattoni et al., 2008a, 2011; Silverman et al., 2010a, 2010c, 2012; Wöhr et al., 2011; Yang et al., 2007a, 2007b, 2009, 2011b, 2012).”
Self-citationLau, J. C., Lerch, J. P., Sled, J. G., Henkelman, R. M., Evans, A. C., & Bedell, B. J. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.04.252 · Cited by 152
Self-citationLow stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism
Silverman, J. L., Yang, M., Turner, S. M., Katz, A. M., Bell, D. B., Koenig, J. I., & Crawley, J. N. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.09.059 · Cited by 146
Self-citationPreparation of fixed mouse brains for MRI
Cahill, L. S., Laliberté, C. L., Ellegood, J., Spring, S., Gleave, J. A., van Eede, M. C., Lerch, J. P., & Henkelman, R. M. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.01.100 · Cited by 146
Self-citationDefensor, E. B., Pearson, B. L., Pobbe, R. L. H., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.10.033 · Cited by 136
Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease
Lerch, J. P., Carroll, J. B., Dorr, A. E., Spring, S., Evans, A. C., Hayden, M. R., Sled, J. G., & Henkelman, R. M. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.02.019 · Cited by 134
Self-citationReduced ultrasonic vocalizations in vasopressin 1b knockout mice
Scattoni, M. L., McFarlane, H. G., Zhodzishsky, V., Caldwell, H. K., YOUNG, W., Ricceri, L., & Crawley, J. N. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.09.034 · Cited by 134
Self-citationMRI Phenotyping of Genetically Altered Mice
Lerch, J. P., Sled, J. G., & Henkelman, R. M. (2010) · Methods in molecular biology · doi:10.1007/978-1-61737-992-5_17 · Cited by 134
Self-citationSocial deficits in BTBR T + tf/J mice are unchanged by cross‐fostering with C57BL/6J mothers
Yang, M., Zhodzishsky, V., & Crawley, J. N. (2007) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2007.09.008 · Cited by 132
Self-citationPobbe, R. L. H., Pearson, B. L., Defensor, E. B., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.06.025 · Cited by 124
Yang, M. (2007) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.001.2007 · Cited by 124
Magnetic resonance histology for morphologic phenotyping
Johnson, G. A., Cofer, G. P., Fubara, B. N., Gewalt, S. L., Hedlund, L. W., & Maronpot, R. R. (2002) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10175 · Cited by 122
Nieman, B. J., Flenniken, A. M., Adamson, S. L., Henkelman, R. M., & Sled, J. G. (2006) · Physiological Genomics · doi:10.1152/physiolgenomics.00217.2005 · Cited by 122
Self-citationGeneral and social anxiety in the BTBR T+ tf/J mouse strain
Pobbe, R. L. H., Defensor, E. B., Pearson, B. L., Bolivar, V. J., Blanchard, D. C., & Blanchard, R. J. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.08.039 · Cited by 121
Wang, Y., Zhang, J., Mori, S., & Nathans, J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3221-05.2006 · Cited by 117
Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability
Yang, M., Clarke, A. M., & Crawley, J. N. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06714.x · Cited by 117
Self-citationBeacher, F. D. C. C., Minati, L., Baron‐Cohen, S., Lombardo, M. V., Lai, M., Gray, M. A., Harrison, N. A., & Critchley, H. (2011) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2880 · Cited by 117
Ameis, S. H., Fan, J., Rockel, C. P., Voineskos, A. N., Lobaugh, N. J., Soorya, L. V., Wang, A. T., Hollander, E., & Anagnostou, E. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028044 · Cited by 113
Low sociability in BTBR T+tf/J mice is independent of partner strain
Yang, M., Abrams, D. N., Zhang, J. Y., Weber, M. D., Katz, A. M., Clarke, A. M., Silverman, J. L., & Crawley, J. N. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.12.025 · Cited by 112
Self-citationAnatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging
Ellegood, J., Pacey, L. K. K., Hampson, D. R., Lerch, J. P., & Henkelman, R. M. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.03.038 · Cited by 110
Self-citationSocial peers rescue autism‐relevant sociability deficits in adolescent mice
Yang, M., Perry, K., Weber, M. D., Katz, A. M., & Crawley, J. N. (2011) · Autism Research · doi:10.1002/aur.163 · Cited by 106
Self-citationFluoxetine but not risperidone increases sociability in the BTBR mouse model of autism
Chadman, K. K. (2010) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2010.09.012 · Cited by 105
Roullet, F., Wöhr, M., & Crawley, J. N. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.06.004 · Cited by 97
Self-citationZhang, J., van Zijl, P. C. M., & Mori, S. (2002) · NeuroImage · doi:10.1006/nimg.2001.1012 · Cited by 96
A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism
Frazier, T. W., Keshavan, M. S., Minshew, N. J., & Hardan, A. Y. (2012) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-012-1478-z · Cited by 81
Brain abnormalities in a Neuroligin3 R451C knockin mouse model associated with autism
Ellegood, J., Lerch, J. P., & Henkelman, R. M. (2011) · Autism Research · doi:10.1002/aur.215 · Cited by 70
Self-citationMagnetic resonance imaging for detection and analysis of mouse phenotypes
Nieman, B. J., Bock, N. A., Bishop, J., Chen, X., Sled, J. G., Rossant, J., & Henkelman, R. M. (2005) · NMR in Biomedicine · doi:10.1002/nbm.981 · Cited by 69
Self-citationCasanova, M. F., El-Baz, A. S., Elnakib, A. A., Switala, A. E., Williams, E. L., Williams, D. L., Minshew, N. J., & Conturo, T. E. (2011) · Autism · doi:10.1177/1362361310386506 · Cited by 67
Ren, T., Zhang, J., Plachez, C., Mori, S., & Richards, L. J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2787-07.2007 · Cited by 64
Multiple mouse biological loading and monitoring system for MRI
Dazai, J., Bock, N. A., Nieman, B. J., Davidson, L., Henkelman, R. M., & Chen, X. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20215 · Cited by 63
Self-citationMagnetic resonance microscopy‐based analyses of the brains of normal and ethanol‐exposed fetal mice
O’Leary‐Moore, S. K., Parnell, S. E., Godin, E. A., Dehart, D. B., Ament, J. J., Khan, A. A., Johnson, G. A., Styner, M. A., & Sulik, K. K. (2010) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20719 · Cited by 61
Thomas, D. L., Vita, E. D., Roberts, S., Turner, R., Yousry, T. A., & Ordidge, R. J. (2004) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20106 · Cited by 54
Ellegood, J., Henkelman, R. M., & Lerch, J. P. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00037 · Cited by 51
Self-citationCyr, M., Caron, M. G., Johnson, G. A., & Laakso, A. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.01.039 · Cited by 50
Errijgers, V., Dam, D. V., Gantois, I., Ginneken, C. J. V., Grossman, A. W., D’Hooge, R., Deyn, P. P. D., & Kooy, R. F. (2006) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2006.00282.x · Cited by 47
Cerebral asymmetries in 12-week-old C57Bl/6J mice measured by magnetic resonance imaging
Spring, S., Lerch, J. P., Wetzel, M. K., Evans, A. C., & Henkelman, R. M. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.12.043 · Cited by 47
Self-citationMR technology for biological studies in mice
Nieman, B. J., Bishop, J. E., Dazai, J., Bock, N. A., Lerch, J. P., Feintuch, A., Chen, X., Sled, J. G., & Henkelman, R. M. (2007) · NMR in Biomedicine · doi:10.1002/nbm.1142 · Cited by 43
Self-citationKumar, M., Kim, S., Pickup, S., Chen, R., Fairless, A. H., Ittyerah, R., Abel, T. G., Brodkin, E. S., & Poptani, H. (2012) · Brain Research · doi:10.1016/j.brainres.2012.03.041 · Cited by 35
Davies, S. W., & Roberts, P. J. J. (1988) · Science · doi:10.1126/science.2969147 · Cited by 25
Seo, Y., Shinar, H., Morita, Y., & Navon, G. (1999) · Magnetic Resonance in Medicine · doi:10.1002/(sici)1522-2594(199909)42:3 · Cited by 19
Cited by
Sorted by citations
Autism spectrum disorder: neuropathology and animal models
Varghese, M., Keshav, N., Jacot-Descombes, S., Warda, T., Wicinski, B., Dickstein, D. L., Harony-Nicolas, H., De Rubeis, S., Drapeau, E., Buxbaum, J. D., et al. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1736-4 · Cited by 536
Millan, M. J., Fone, K. C. F., Steckler, T., & Horan, W. P. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.03.008 · Cited by 376
Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., DiCicco-Bloom, E., Lai, J. K. Y., Foster, J. A., Peñagarikano, O., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.98 · Cited by 288
Self-citationPortmann, T., Yang, M., Mao, R., Panagiotakos, G., Ellegood, J., Dolen, G., Bader, P. L., Grueter, B. A., Goold, C., Fisher, E., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.036 · Cited by 245
Self-citationHan, S., Tai, C., Jones, C. J., Scheuer, T., & Catterall, W. A. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.016 · Cited by 231
Metadata
- Authors
- Ellegood, J., Babineau, B. A., Henkelman, R. M., Lerch, J. P., & Crawley, J. N.
- Affiliations
- Hospital for Sick Children (CA)
- National Institute of Mental Health (US)
- University of Toronto (CA)
- Corresponding author
- Ellegood, Jacob
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 70
- Pages
- 288-300
- ISSN
- 1053-8119 (ISSN-L)
- PMC
- PMC3595420
- OpenAlex
- W2096358139
- Cited by
- 135
- References
- 87
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 5 · 2023: 5 · 2022: 9 · 2021: 7 · 2020: 15 · 2019: 9 · 2018: 14 · 2017: 12 · 2016: 9 · 2015: 11 · 2014: 17 · 2013: 5
- FWCI
- 5.41
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Ontario Mental Health Foundation
- Canadian Institute for Health Research
- National Institute of Mental Health Intramural Research Program
- Ontario Brain Institute
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Keywords
- autism spectrum disorder, sociability, self-grooming, repetitive behavior, striatal volume, white matter microstructure, corpus callosum, hippocampal commissure, brain volume, inbred mouse strains
- MeSH terms
- Animals, Autistic Disorder, Behavior, Animal, Brain, Disease Models, Animal, Female, Magnetic Resonance Imaging, Male, Mice, Inbred C57BL, Mice, Inbred Strains, Mice, Diffusion Tensor Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
