Cited by 52Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

Imaging the neural effects of cognitive bias modification training

Open access
Wiers, Corinde E., Wiers, Reinout W.·2017·NeuroImage

Abstract

Cognitive bias modification (CBM) was first developed as an experimental tool to examine the causal role of cognitive biases, and later developed into complementary interventions in experimental psychopathology research. CBM involves the "re-training" of implicit biases by means of multiple trials of computerized tasks, and has been demonstrated to change anxious, depressive and drug-seeking behavior, including clinically relevant effects. Recently, the field has progressed by combining CBM with neuroimaging techniques, which provides insight into neural mechanisms underlying how CBM affects implicit biases in anxiety, depression, and addiction, and potentially other pathologies. This narrative literature review summarizes the state of the art of studies on the neural effects of CBM and provides directions for future research in the field. A total of 13 published studies were found and discussed: n=9 in anxiety, n=2 in depressive behavior, and n=2 in addiction.

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Crossref · 10.1016/j.neuroimage.2016.07.041

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  • Anxiety is linked with dysfunctional interactions among multiple brain regions, including the salience network and executive control network.

    “Such research links anxiety with dysfunctional interactions among multiple brain regions, including the salience network (supporting automatic threat evaluation/detection, and spanning amygdala/insula/frontal regions) and executive control network (supporting goal-directed activity, and spanning frontal/parietal regions) [110-115].”
  • The salience network supports automatic threat evaluation/detection and spans amygdala/insula/frontal regions.

    “Such research links anxiety with dysfunctional interactions among multiple brain regions, including the salience network (supporting automatic threat evaluation/detection, and spanning amygdala/insula/frontal regions) and executive control network (supporting goal-directed activity, and spanning frontal/parietal regions) [110-115].”
  • Research on ABM training effects on neural functioning implicates regions involved in threat salience evaluation, attention, and cognitive control (e.g., amygdala, insula, frontal regions).

    “Research investigating the effects of ABM training on neural functioning in anxiety is in its infancy, and implicates regions involved in threat salience evaluation, attention, and cognitive control (e.g., amygdala, insula, frontal regions) [110].”
  • The executive control network supports goal-directed activity and spans frontal/parietal regions.

    “Such research links anxiety with dysfunctional interactions among multiple brain regions, including the salience network (supporting automatic threat evaluation/detection, and spanning amygdala/insula/frontal regions) and executive control network (supporting goal-directed activity, and spanning frontal/parietal regions) [110-115].”
  • Dysfunctional connections between these regions may influence treatment outcome.

    “Dysfunctional connections between these regions may influence treatment outcome [109,110].”

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Authors
Wiers, C. E., & Wiers, R. W.
Affiliations
  • National Institutes of Health (US)
  • University of Amsterdam (NL)
Corresponding author
Wiers, Corinde E.
Venue
NeuroImage
Publisher
Elsevier BV
Published
2017-05
Volume
151
Pages
81-91
ISSN
1053-8119 (ISSN-L)
OpenAlex
W2477157151
Cited by
52
References
141
Citations by year
2026: 4 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 5 · 2021: 6 · 2020: 8 · 2019: 8 · 2018: 6 · 2017: 5
FWCI
0.84
Type
journal article
Language
en
Open access
Locations
  • NeuroImage (publishedVersion)
  • PubMed (publishedVersion)
  • UvA-DARE (University of Amsterdam) (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Funders
German Research Foundation
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords
cognitive bias modification, implicit bias, neural mechanisms, anxiety, depression, addiction, drug-seeking behavior, neuroimaging
MeSH terms
Anxiety Disorders, Brain, Depressive Disorder, Humans, Cognitive Behavioral Therapy, Substance-Related Disorders

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