The DOI matches its Crossref record; 66 of the 68 references it cites were found in a registry or an index.
Distributed Network Actions by Nicotine Increase the Threshold for Spike-Timing-Dependent Plasticity in Prefrontal Cortex
Open accessAbstract
Nicotine enhances attention and working memory by activating nicotinic acetylcholine receptors (nAChRs). The prefrontal cortex (PFC) is critical for these cognitive functions and is also rich in nAChR expression. Specific cellular and synaptic mechanisms underlying nicotine's effects on cognition remain elusive. Here we show that nicotine exposure increases the threshold for synaptic spike-timing-dependent potentiation (STDP) in layer V pyramidal neurons of the mouse PFC. During coincident presynaptic and postsynaptic activity, nicotine reduces dendritic calcium signals associated with action potential propagation by enhancing GABAergic transmission. This results from a series of presynaptic actions involving different PFC interneurons and multiple nAChR subtypes. Pharmacological block of nAChRs or GABA(A) receptors prevented nicotine's actions and restored STDP, as did increasing dendritic calcium signals with stronger postsynaptic activity. Thus, by activating nAChRs distributed throughout the PFC neuronal network, nicotine affects PFC information processing and storage by increasing the amount of postsynaptic activity necessary to induce STDP.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In contrast, in layer V pyramidal neurons, activation of presynaptic β2* nAChRs on glutamatergic inputs from the thalamus strongly enhances activity of these neurons (Gioanni et al. 1999; Lambe et al. 2003; Couey et al. 2007; Poorthuis et al. 2012).”
From Short- and Long-Term Consequences of Nicotine Exposure during Adolescence for Prefrontal Cortex Neuronal Network Function (2012) · cites this paper as Couey et al. 2007
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“This may affect plasticity and refinement of cortical connections (Couey et al. 2007)”
From Short- and Long-Term Consequences of Nicotine Exposure during Adolescence for Prefrontal Cortex Neuronal Network Function (2012) · cites this paper as Couey et al. 2007
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In addition, nicotine in the mPFC changes the rules for spike-timing-dependent plasticity and thereby prevents synaptic potentiation (34).”
From Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex (2012) · cites this paper as [34]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“the majority of interneurons express nAChRs that are composed of α4β2*, although they also express other subunits (34)”
From Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex (2012) · cites this paper as [34]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Increased inhibition can lead to blockade of long-term potentiation (LTP) induction in the hippocampus (Ji et al. 2001) and increase in the threshold for induction of spike-timing-dependent plasticity (STDP) (Couey et al. 2007).”
From Short- and Long-Term Consequences of Nicotine Exposure during Adolescence for Prefrontal Cortex Neuronal Network Function (2012) · cites this paper as Couey et al. 2007
The cited source says what the claim attributes to it.
In the citing paper
“nAChR, which enhances both excitatory and inhibitory synaptic transmission (Lambe et al. 2003; Couey et al. 2007; Poorthuis et al. 2012).”
From Short- and Long-Term Consequences of Nicotine Exposure during Adolescence for Prefrontal Cortex Neuronal Network Function (2012) · cites this paper as Couey et al. 2007
The cited source says what the claim attributes to it.
In the citing paper
“In addition, different types of PFC interneurons in the mPFC express both α7 and α4β2-containing nAChRs on their cell bodies (34), and nAChR stimulation increases GABAergic transmission (34).”
In the citing paper
“In contrast to the ability of nAChR stimulation to promote LTP in a number of brain areas, nAChR-mediated facilitation of GABA release reduces calcium levels in prefronto-cortical dendrites (Couey et al., 2007).”
From Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior (2012) · cites this paper as Couey et al., 2007
In the citing paper
“The fast inhibition is at least partially mediated by the actions of both nAChRs and mAChRs that increase the excitability and firing rates of dendrite-targeting GABAergic interneurons (Arroyo et al., 2012; Couey et al., 2007; Fanselow et al., 2008; Ferezou et al., 2002; Gulledge et al., 2007; Kawaguchi and Kubota, 1997).”
From Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior (2012) · cites this paper as Couey et al., 2007
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bi, G.-Q., & Poo, M.-M. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-24-10464.1998 · Cited by 4,744
Regulation of Synaptic Efficacy by Coincidence of Postsynaptic APs and EPSPs
Markram, H., Lübke, J., Frotscher, M., & Sakmann, B. (1997) · Science · doi:10.1126/science.275.5297.213 · Cited by 3,832
Tsien, R. Y. (1980) · Biochemistry · doi:10.1021/bi00552a018 · Cited by 2,261
GABAergic cell subtypes and their synaptic connections in rat frontal cortex
Kawaguchi, Y. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.6.476 · Cited by 1,416
A Synaptically Controlled, Associative Signal for Hebbian Plasticity in Hippocampal Neurons
Magee, J. C., & Johnston, D. (1997) · Science · doi:10.1126/science.275.5297.209 · Cited by 1,340
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
Dalley, J. W., Cardinal, R. N., & Robbins, T. W. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.006 · Cited by 1,329
Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
McGehee, D. S., Heath, M. J. S., Gelber, S., Devay, P., & Role, L. W. (1995) · Science · doi:10.1126/science.7569895 · Cited by 1,070
Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons
McGehee, D. S., & Role, L. W. (1995) · Annual Review of Physiology · doi:10.1146/annurev.ph.57.030195.002513 · Cited by 1,022
Dendritic spines as basic functional units of neuronal integration
Yuste, R., & Denk, W. (1995) · Nature · doi:10.1038/375682a0 · Cited by 950
Hippocampal synaptic transmission enhanced by low concentrations of nicotine
Gray, R. G. F., Rajan, A. S., Radcliffe, K. A., Yakehiro, M., & Dani, J. A. (1996) · Nature · doi:10.1038/383713a0 · Cited by 947
Cited by
Sorted by citations
Spike Timing–Dependent Plasticity: A Hebbian Learning Rule
Caporale, N., & Dan, Y. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125639 · Cited by 1,997
Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior
Picciotto, M. R., Higley, M. J., & Mineur, Y. S. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.036 · Cited by 1,404
Benchenane, K., Peyrache, A., Khamassi, M., Tierney, P. L., Gioanni, Y., Battaglia, F. P., & Wiener, S. I. (2010) · Neuron · doi:10.1016/j.neuron.2010.05.013 · Cited by 872
A disinhibitory microcircuit for associative fear learning in the auditory cortex
Letzkus, J. J., Wolff, S. B. E., Meyer, E. M. M., Tovote, P., Courtin, J., Herry, C., & Lüthi, A. (2011) · Nature · doi:10.1038/nature10674 · Cited by 840
Dendritic Excitability and Synaptic Plasticity
Sjöström, P. J., Rancz, E. A., Roth, A., & Häusser, M. (2008) · Physiological Reviews · doi:10.1152/physrev.00016.2007 · Cited by 740
Nicotine addiction and nicotinic receptors: lessons from genetically modified mice
Changeux, J.-P. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2849 · Cited by 453
Sofouglu, M., Herman, A. I., Robinson, C. D., & Waters, A. J. (2014) · Lincoln (University of Nebraska) · Cited by 417
Neuromodulated Spike-Timing-Dependent Plasticity, and Theory of Three-Factor Learning Rules
Frémaux, N., & Wulfram Gerstner, B. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2015.00085 · Cited by 449
Oscillations in the prefrontal cortex: a gateway to memory and attention
Benchenane, K., Tiesinga, P. H., & Battaglia, F. P. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.01.004 · Cited by 366
Goriounova, N. A., & Mansvelder, H. D. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a012120 · Cited by 307
“When activated by nAChR stimulation, interneurons can alter activity and plasticity in pyramidal neurons (Xiang et al. 1998; Alkondon et al. 2000; Ji and Dani 2000; Ji et al. 2001; Couey et al. 2007).”
BackgroundInfluentialSelf-citationCompartmentalization of GABAergic inhibition by dendritic spines
Chiu, C. Q., Lur, G., Morse, T. M., Carnevale, N. T., Ellis-Davies, G. C. R., & Higley, M. J. (2013) · Science · doi:10.1126/science.1234274 · Cited by 307
Goto, Y., Yang, C. R., & Otani, S. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.08.026 · Cited by 316
Projection-Specific Neuromodulation of Medial Prefrontal Cortex Neurons
Dembrow, N. C., Chitwood, R. A., & Johnston, D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3644-10.2010 · Cited by 294
Cognitive Effects of Nicotine: Recent Progress
Valentine, G. W., & Sofuoglu, M. (2017) · Current Neuropharmacology · doi:10.2174/1570159x15666171103152136 · Cited by 302
Timing is not everything: neuromodulation opens the STDP gate
Pawlak, V. (2010) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2010.00146 · Cited by 267
Neuromodulation of Spike-Timing-Dependent Plasticity: Past, Present, and Future
Brzosko, Z., Mierau, S. B., & Paulsen, O. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.041 · Cited by 267
Why do patients with schizophrenia smoke?
Winterer, G. (2010) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e3283366643 · Cited by 238
Smoking, quitting, and psychiatric disease: A review
Aubin, H., Rollema, H., Svensson, T. H., & Winterer, G. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.06.007 · Cited by 241
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking
Van den Oever, M. C., Goriounova, N. A., Wan Li, K., Van der Schors, R. C., Binnekade, R., Schoffelmeer, A. N. M., Mansvelder, H. D., Smit, A. B., Spijker, S., & De Vries, T. J. (2008) · Nature Neuroscience · doi:10.1038/nn.2165 · Cited by 206
Self-citationNeural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses
Miwa, J. M., Freedman, R., & Lester, H. A. (2011) · Neuron · doi:10.1016/j.neuron.2011.03.014 · Cited by 205
The Chronotron: A Neuron That Learns to Fire Temporally Precise Spike PatternsPreprint
Florian, R. V. (2010) · Nature Precedings · doi:10.1371/journal.pone.0040233 · Cited by 211
Sakata, K., Woo, N. H., Martinowich, K., Greene, J. S., Schloesser, R. J., Shen, L., & Lu, B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811431106 · Cited by 200
Meredith, R. M., Holmgren, C. D., Weidum, M., Burnashev, N., & Mansvelder, H. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.028 · Cited by 190
Self-citationNicotinic acetylcholine receptor β2 subunits in the medial prefrontal cortex control attention
Guillem, K., Bloem, B., Poorthuis, R. B., Loos, M., Smit, A. B., Maskos, U., Spijker, S., & Mansvelder, H. D. (2011) · Science · doi:10.1126/science.1207079 · Cited by 191
Self-citationNicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex
Yang, Y., Paspalas, C. D., Jin, L. E., Picciotto, M. R., Arnsten, A. F. T., & Wang, M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307849110 · Cited by 188
Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron
Ramaswamy, S., & Markram, H. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00233 · Cited by 204
Neuromodulation by acetylcholine: examples from schizophrenia and depression
Higley, M. J., & Picciotto, M. R. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.06.004 · Cited by 184
Layer- and Cell Type-Specific Modulation of Excitatory Neuronal Activity in the Neocortex
Radnikow, G., & Feldmeyer, D. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00001 · Cited by 185
Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors
McKay, B. E., Placzek, A. N., & Dani, J. A. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.07.001 · Cited by 181
Layer-Specific Modulation of the Prefrontal Cortex by Nicotinic Acetylcholine Receptors
Poorthuis, R. B., Bloem, B., Schak, B., Wester, J., de Kock, C. P. J., & Mansvelder, H. D. (2013) · Cerebral Cortex · doi:10.1093/cercor/bhr390 · Cited by 176
Self-citationvan Aerde, K. I., & Feldmeyer, D. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht278 · Cited by 180
Dickinson, J. A., Kew, J. N. C., & Wonnacott, S. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.046623 · Cited by 159
Pattwell, S. S., Bath, K. G., Perez-Castro, R., Lee, F. S., Chao, M. V., & Ninan, I. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.5205-11.2012 · Cited by 156
Baskin-sommers, A. R., & Foti, D. (2015) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2015.01.011 · Cited by 173
Bloem, B., Poorthuis, R. B., & Mansvelder, H. D. (2014) · Frontiers in Neural Circuits · doi:10.3389/fncir.2014.00017 · Cited by 163
Self-citationXu, T., & Yao, W. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004108107 · Cited by 149
The Nicotinic Acetylcholine Receptor 5 Subunit Plays a Key Role in Attention Circuitry and Accuracy
Bailey, C. D. C., De Biasi, M., Fletcher, P. J., & Lambe, E. K. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.2258-10.2010 · Cited by 146
Sakata, K., Martinowich, K., Woo, N. H., Schloesser, R. J., Jimenez, D. V., Ji, Y., Shen, L., & Lu, B. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222872110 · Cited by 146
Wu, H., Pereira, E. F. R., Bruno, J. P., Pellicciari, R., Albuquerque, E. X., & Schwarcz, R. M. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-009-9235-2 · Cited by 146
Glutamatergic synaptic plasticity in the mesocorticolimbic system in addiction
van Huijstee, A. N., & Mansvelder, H. D. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00466 · Cited by 158
Self-citationBloem, B., Schoppink, L., Rotaru, D. C., Faiz, A., Hendriks, P., Mansvelder, H. D., van de Berg, W. D. J., & Wouterlood, F. G. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3011-14.2014 · Cited by 143
Self-citationImportance of the nicotinic acetylcholine receptor system in the prefrontal cortex
Wallace, T. L., & Bertrand, D. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.04.001 · Cited by 133
Livingstone, P. D., Srinivasan, J., Kew, J. N. C., Dawson, L. A., Gotti, C., Moretti, M., Shoaib, M., & Wonnacott, S. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06613.x · Cited by 133
Cellular, Synaptic and Network Effects of Acetylcholine in the Neocortex
Colangelo, C., Shichkova, P., Keller, D. X., Markram, H., & Ramaswamy, S. (2019) · Frontiers in Neural Circuits · doi:10.3389/fncir.2019.00024 · Cited by 143
Parikh, V., Ji, J., Decker, M. W., & Sarter, M. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5712-09.2010 · Cited by 133
Nicotinic acetylcholine receptors and the ascending dopamine pathways
Livingstone, P. D., & Wonnacott, S. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.06.004 · Cited by 139
Presynaptic Opioid and Nicotinic Receptor Modulation of Dopamine Overflow in the Nucleus Accumbens
Britt, J. P., & McGehee, D. S. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4275-07.2008 · Cited by 130
Mechanisms Underlying the Rules for Associative Plasticity at Adult Human Neocortical Synapses
Verhoog, M. B., Goriounova, N. A., Obermayer, J., Stroeder, J., Hjorth, J. J. J., Testa-Silva, G., Baayen, J. C., de Kock, C. P. J., Meredith, R. M., & Mansvelder, H. D. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3158-13.2013 · Cited by 127
Self-citationHowe, W. M., Berry, A. S., François, J., Gilmour, G., Carp, J., Tricklebank, M. D., Lustig, C., & Sarter, M. F. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5809-12.2013 · Cited by 136
Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits
Mansvelder, H. D., Mertz, M., & Role, L. W. (2009) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2009.01.007 · Cited by 126
Self-citationSpatiotemporal specificity in cholinergic control of neocortical function
Muñoz, W., & Rudy, B. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.02.015 · Cited by 124
van den Oever, M. C., Lubbers, B. R., Goriounova, N. A., Li, K. W., van der Schors, R. C., Loos, M., Riga, D., Wiskerke, J., Binnekade, R., Stegeman, M., et al. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.90 · Cited by 126
Self-citationChrna2-Martinotti cells synchronize layer 5 type A pyramidal cells via rebound excitation
Hilscher, M. M., Leão, R. N., Edwards, S. J., Leão, K. E., & Kullander, K. (2017) · PLoS Biology · doi:10.1371/journal.pbio.2001392 · Cited by 118
Cholinergic control of GABA release: emerging parallels between neocortex and hippocampus
Lawrence, J. J. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.03.008 · Cited by 115
Prefrontal nicotinic receptors control novel social interaction between mice
Avale, M. E., Chabout, J., Pons, S., Serreau, P., De Chaumont, F., Olivo‐Marin, J., Bourgeois, J., Maskos, U., Changeux, J., & Granon, S. (2011) · The FASEB Journal · doi:10.1096/fj.10-178558 · Cited by 114
Pistillo, F., Clementi, F., Zoli, M., & Gotti, C. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2014.10.002 · Cited by 120
Ninan, I. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07430.x · Cited by 110
Developmental Excitation of Corticothalamic Neurons by Nicotinic Acetylcholine Receptors
Kassam, S. M., Herman, P. M., Goodfellow, N. M., Alves, N. C., & Lambe, E. K. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2645-08.2008 · Cited by 100
Molecular and Cellular Mechanisms of Action of Nicotine in the CNS
Barik, J., & Wonnacott, S. (2009) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-69248-5_7 · Cited by 112
Brief Bursts Self-Inhibit and Correlate the Pyramidal Network
Berger, T. K., Silberberg, G., Perin, R., & Markram, H. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000473 · Cited by 112
Nicotinic actions on neuronal networks for cognition: General principles and long-term consequences
Poorthuis, R. B., Goriounova, N. A., Couey, J. J., & Mansvelder, H. D. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.04.031 · Cited by 102
Self-citationThe role of nicotinic acetylcholine receptors in autosomal dominant nocturnal frontal lobe epilepsy
Becchetti, A., Aracri, P., Meneghini, S., Brusco, S., & Amadeo, A. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00022 · Cited by 107
Wing, V. C., Wass, C., Soh, D. W., & George, T. P. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06261.x · Cited by 99
Chatterjee, S., & Bartlett, S. E. (2010) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152710790966597 · Cited by 100
Obermayer, J., Heistek, T. S., Kerkhofs, A., Goriounova, N. A., Kroon, T., Baayen, J. C., Idema, S., Testa-Silva, G., Couey, J. J., & Mansvelder, H. D. (2018) · Nature Communications · doi:10.1038/s41467-018-06628-w · Cited by 114
Self-citationObermayer, J., Verhoog, M. B., Luchicchi, A., & Mansvelder, H. D. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00100 · Cited by 106
Self-citationLayer-specific cholinergic control of human and mouse cortical synaptic plasticity
Verhoog, M. B., Obermayer, J., Kortleven, C., Wilbers, R., Wester, J., Baayen, J. C., de Kock, C. P. J., Meredith, R. M., & Mansvelder, H. D. (2016) · Nature Communications · doi:10.1038/ncomms12826 · Cited by 104
Self-citationKonradsson‐Geuken, Å., Wu, H., Gash, C. R., Alexander, K., Campbell, A., Sozeri, Y., Pellicciari, R., Schwarcz, R. M., & Bruno, J. P. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.05.052 · Cited by 96
Thirugnanasambandam, N., Grundey, J., Adam, K., Drees, A., Skwirba, A. C., Lang, N., Paulus, W., & Nitsche, M. A. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.227 · Cited by 91
Cortical disinhibitory circuits: cell types, connectivity and function
Kullander, K., & Topolnik, L. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.04.009 · Cited by 86
The effect of α7 nicotinic receptor activation on glutamatergic transmission in the hippocampus
Cheng, Q., & Yakel, J. L. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.07.015 · Cited by 85
Garduño, J., Galindo-Charles, L., Jiménez-Rodríguez, J., Galarraga, E., Tapia, D., Mihailescu, S., & Hernandez-Lopez, S. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0941-12.2012 · Cited by 83
Zhong, C., Du, C., Hancock, M., Mertz, M., Talmage, D. A., & Role, L. W. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0381-08.2008 · Cited by 83
Tosti, B., Corrado, S., Mancone, S., Libero, T. D., Rodio, A., Andrade, A., & Diotaiuti, P. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1358481 · Cited by 93
GABA B modulation of dopamine release in the nucleus accumbens core
Pitman, K. A., Puil, E., & Borgland, S. L. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12733 · Cited by 81
Terrando, N., Yang, T., Ryu, J. K., Newton, P. T., Monaco, C. G., Feldmann, M., Ma, D., Akassoglou, K., & Maze, M. (2014) · Molecular Medicine · doi:10.2119/molmed.2014.00143 · Cited by 80
GABA-A Receptor Inhibition of Local Calcium Signaling in Spines and Dendrites
Marlin, J. J., & Carter, A. G. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0869-13.2014 · Cited by 79
Zhou, H.-C., Sun, Y., Cai, W., He, X.-T., Yi, F., Li, B., & Zhang, X. (2013) · Learning & Memory · doi:10.1101/lm.030411.113 · Cited by 77
Endogenous kynurenic acid regulates extracellular GABA levels in the rat prefrontal cortex
Beggiato, S., Tanganelli, S., Fuxé, K., Antonelli, T., Schwarcz, R. M., & Ferraro, L. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.02.019 · Cited by 74
Luchicchi, A., Bloem, B., Viaña, J. N. M., Mansvelder, H. D., & Role, L. W. (2014) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2014.00024 · Cited by 74
Self-citationCholinergic modulation of dopamine pathways through nicotinic acetylcholine receptors
de Kloet, S. F., Mansvelder, H. D., & De Vries, T. J. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.07.014 · Cited by 69
Self-citationYiannakas, A., & Rosenblum, K. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00335 · Cited by 72
Cheng, Q., & Yakel, J. L. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2973-13.2014 · Cited by 68
STDP in the developing sensory neocortex
Larsen, R. S. (2010) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2010.00009 · Cited by 69
Goriounova, N. A., & Mansvelder, H. D. (2012) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2012.00003 · Cited by 65
Self-citationPPAR-Alpha Agonists as Novel Antiepileptic Drugs: Preclinical Findings
Puligheddu, M., Pillolla, G., Melis, M., Lecca, S., Marrosu, F., Demontis, M., Scheggi, S., Carta, G., Murru, E., Aroni, S., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064541 · Cited by 61
Edeline, J. (2012) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2012.00045 · Cited by 65
Bergstrom, H. C., McDonald, C. G., French, H. T., & Smith, R. F. (2008) · Synapse · doi:10.1002/syn.20467 · Cited by 60
Aracri, P., Consonni, S., Morini, R., Perrella, M., Rodighiero, S., Amadeo, A., & Becchetti, A. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp214 · Cited by 60
Proulx, É., Piva, M., Tian, M. K., Bailey, C. D. C., & Lambe, E. K. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1481-3 · Cited by 66
The role of dendritic inhibition in shaping the plasticity of excitatory synapses
Bar-Ilan, L., Gidon, A., & Segev, I. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00118 · Cited by 61
Bekenstein, U., Mishra, N., Milikovsky, D. Z., Hanin, G., Zelig, D., Sheintuch, L., Berson, A., Greenberg, D., Friedman, A., & Soreq, H. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701201114 · Cited by 59
Foncelle, A., Mendes, A., Jędrzejewska‐Szmek, J., Valtcheva, S., Berry, H., Blackwell, K. T., & Venance, L. (2018) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2018.00049 · Cited by 67
Laviolette, S. R. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108411 · Cited by 57
Cell Type-Specific Effects of Adenosine on Cortical Neurons
van Aerde, K. I., Qi, G., & Feldmeyer, D. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht274 · Cited by 53
Goriounova, N. A., & Mansvelder, H. D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5502-11.2012 · Cited by 51
Self-citationPrefrontal neuromodulation by nicotinic receptors for cognitive processes
Coura, R., & Granon, S. (2012) · Psychopharmacology · doi:10.1007/s00213-011-2596-6 · Cited by 57
Edelmann, E., & Leßmann, V. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00025 · Cited by 52
The Molecular and Cellular Neurobiology of Nicotine Abuse in Schizophrenia
Mobascher, A., & Winterer, G. (2008) · Pharmacopsychiatry · doi:10.1055/s-2008-1081463 · Cited by 50
Poorthuis, R. B., & Mansvelder, H. D. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.07.003 · Cited by 54
Self-citation
Metadata
- Authors
- Couey, J. J., Meredith, R. M., Spijker, S., Poorthuis, R. B., Smit, A. B., Brussaard, A. B., & Mansvelder, H. D.
- Affiliations
- Vrije Universiteit Amsterdam (NL)
- Corresponding author
- Mansvelder, Huibert D.
- ORCID
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2007-04
- Volume
- 54
- Issue
- 1
- Pages
- 73-87
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2077516679
- Cited by
- 253
- References
- 68
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 5 · 2023: 9 · 2022: 9 · 2021: 13 · 2020: 5 · 2019: 14 · 2018: 18 · 2017: 15 · 2016: 11 · 2015: 12 · 2014: 21 · 2013: 22 · 2012: 18
- FWCI
- 7.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 2335 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- VU Research Portal (publishedVersion, other-oa)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- Koninklijke Nederlandse Akademie van Wetenschappen
- ZonMw
- Medical Research Council
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- nicotine, nicotinic acetylcholine receptors, spike-timing-dependent plasticity, prefrontal cortex, layer 5 pyramidal neurons, GABAergic neurotransmission, GABAA receptor, presynaptic inhibition, nAChR subtypes, working memory, attention
- MeSH terms
- Action Potentials, Animals, Animals, Newborn, Drug Interactions, Mice, Inbred C57BL, Models, Neurological, Nerve Net, Neuronal Plasticity, Neurons, Nicotine, Reaction Time, Receptors, Nicotinic, Prefrontal Cortex, Nicotinic Agonists, GABA Antagonists, Excitatory Postsynaptic Potentials, Calcium Signaling, Reverse Transcriptase Polymerase Chain Reaction, Mice, In Vitro Techniques
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
