Early somatostatin interneuron connectivity mediates the maturation of deep layer cortical circuits
Open accessAbstract
The precise connectivity of somatostatin and parvalbumin cortical interneurons is generated during development. An understanding of how these interneuron classes incorporate into cortical circuitry is incomplete but essential to elucidate the roles they play during maturation. Here, we report that somatostatin interneurons in infragranular layers receive dense but transient innervation from thalamocortical afferents during the first postnatal week. During this period, parvalbumin interneurons and pyramidal neurons within the same layers receive weaker thalamocortical inputs, yet are strongly innervated by somatostatin interneurons. Further, upon disruption of the early (but not late) somatostatin interneuron network, the synaptic maturation of thalamocortical inputs onto parvalbumin interneurons is perturbed. These results suggest that infragranular somatostatin interneurons exhibit a transient early synaptic connectivity that is essential for the establishment of thalamic feedforward inhibition mediated by parvalbumin interneurons.
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Transient connections made by early-born SST+ interneurons are required for maturation of PV+ basket cells in deep layers.
“In addition, the transient connections established by early-born SST+ interneurons are also required for the maturation of PV+ basket cells in deep layers (Tuncdemir et al., 2016).”
From Development and Functional Diversification of Cortical Interneurons (2018) · cites this paper as Tuncdemir et al., 2016
Layer 5 SST+ interneurons receive dense transient thalamic inputs during the first postnatal week and innervate layer 4 excitatory neurons, layer 5 pyramidal cells and immature PV+ interneurons.
“Interestingly, layer 5 SST+ interneurons receive dense transient thalamic inputs during the first week of postnatal development and innervate both layer 4 excitatory neurons and layer 5 pyramidal cells and immature PV+ interneurons (Marques-Smith et al., 2016; Tuncdemir et al., 2016).”
From Development and Functional Diversification of Cortical Interneurons (2018) · cites this paper as Tuncdemir et al., 2016
Interneurons that engage in transient connections during the first postnatal week do not appear to be selectively eliminated by programmed cell death.
“Although this remains to be investigated thoroughly, interneurons that engage in transient connections during the first week of postnatal development do not seem to be selectively eliminated through programmed cell death (Tuncdemir et al., 2016).”
From Development and Functional Diversification of Cortical Interneurons (2018) · cites this paper as Tuncdemir et al., 2016
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Cites
Shrestha, S., & Offer, S. M. (2016) · Medical Epigenetics · doi:10.1159/000444713 · Cited by 8,949 · see citing works
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex
Taniguchi, H., He, M., Wu, P., Kim, S., Paik, R., Sugino, K., Kvitsani, D., Fu, Y., Lu, J., Lin, Y., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.026 · Cited by 1,828 · see citing works
Self-citationAutoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse
ANGEVINE, J. B., & SIDMAN, R. L. (1961) · Nature · doi:10.1038/192766b0 · Cited by 1,530 · see citing works
Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex
The Petilla Interneuron Nomenclature Group (PING) (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2402 · Cited by 1,491 · see citing works
Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons
Rudy, B., Fishell, G., Lee, S., & Hjerling‐Leffler, J. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20853 · Cited by 1,420 · see citing works
Self-citationPfeffer, C. K., Xue, M., He, M., Huang, Z. J., & Scanziani, M. (2013) · Nature Neuroscience · doi:10.1038/nn.3446 · Cited by 1,353 · see citing works
Interneuron dysfunction in psychiatric disorders
Marín, O. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3155 · Cited by 1,190 · see citing works
Monosynaptic Restriction of Transsynaptic Tracing from Single, Genetically Targeted Neurons
Wickersham, I. R., Lyon, D. C., Barnard, R. J. O., Mori, T., Finke, S., Conzelmann, K., Young, J. A. T., & Callaway, E. M. (2007) · Neuron · doi:10.1016/j.neuron.2007.01.033 · Cited by 1,176 · see citing works
Self-citationIs there more to gaba than synaptic inhibition?
Owens, D. F., & Kriegstein, A. R. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn919 · Cited by 1,158 · see citing works
Interneuron cell types are fit to function
Kepecs, A., & Fishell, G. (2014) · Nature · doi:10.1038/nature12983 · Cited by 1,110 · see citing works
Self-citationThe subcellular organization of neocortical excitatory connections
Petreanu, L., Mao, T., Sternson, S. M., & Svoboda, K. (2009) · Nature · doi:10.1038/nature07709 · Cited by 1,047 · see citing works
The origin and specification of cortical interneurons
Wonders, C. P., & Anderson, S. A. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1954 · Cited by 980 · see citing works
Eroglu, Ç., Allen, N. J., Susman, M. W., O'Rourke, N. A., Park, C. Y., Özkan, E., Chakraborty, C., Mulinyawe, S. B., Annis, D. S., Huberman, A. D., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.025 · Cited by 893 · see citing works
Disynaptic Inhibition between Neocortical Pyramidal Cells Mediated by Martinotti Cells
Silberberg, G., & Markram, H. (2007) · Neuron · doi:10.1016/j.neuron.2007.02.012 · Cited by 768 · see citing works
GABAergic Hub Neurons Orchestrate Synchrony in Developing Hippocampal Networks
Bonifazi, P., Goldin, M., Picardo, M. A., Jorquera, I., Cattani, A., Bianconi, G., Represa, A., Ben-Ari, Y., & Cossart, R. (2009) · Science · doi:10.1126/science.1175509 · Cited by 695 · see citing works
Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
Tong, Q., Ye, C.-P., Jones, J. E., Elmquist, J. K., & Lowell, B. B. (2008) · Nature Neuroscience · doi:10.1038/nn.2167 · Cited by 689 · see citing works
Somatosensory integration controlled by dynamic thalamocortical feed-forward inhibition
Gabernet, L., Jadhav, S. P., Feldman, D. E., Carandini, M., & Scanziani, M. (2005) · Neuron · doi:10.1016/j.neuron.2005.09.022 · Cited by 599 · see citing works
Chattopadhyaya, B., Di Cristo, G., Higashiyama, H., Knott, G. W., Kuhlman, S. J., Welker, E., & Huang, Z. J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1851-04.2004 · Cited by 596 · see citing works
Postnatal maturation of the GABAergic system in rat neocortex
Luhmann, H. J., & Prince, D. A. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.65.2.247 · Cited by 575 · see citing works
Synaptic basis for intense thalamocortical activation of feedforward inhibitory cells in neocortex
Cruikshank, S. J., Lewis, T. J., & Connors, B. W. (2007) · Nature Neuroscience · doi:10.1038/nn1861 · Cited by 558 · see citing works
The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations
Nery, S., Fishell, G., & Corbin, J. G. (2002) · Nature Neuroscience · doi:10.1038/nn971 · Cited by 558 · see citing works
Self-citationCruikshank, S. J., Urabe, H., Nurmikko, A. V., & Connors, B. W. (2010) · Neuron · doi:10.1016/j.neuron.2009.12.025 · Cited by 459 · see citing works
Trophic actions of GABA on neuronal development
Represa, A., & Ben‐Ari, Y. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.03.010 · Cited by 456 · see citing works
The subplate and early cortical circuits
Kanold, P. O., & Luhmann, H. J. (2010) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153244 · Cited by 440 · see citing works
Distinct Subtypes of Somatostatin-Containing Neocortical Interneurons Revealed in Transgenic Mice
Ma, Y., Hu, H., Berrebi, A. S., Mathers, P. H., & Agmon, A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0661-06.2006 · Cited by 432 · see citing works
Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex
Kapfer, C., Glickfeld, L. L., Atallah, B. V., & Scanziani, M. (2007) · Nature Neuroscience · doi:10.1038/nn1909 · Cited by 427 · see citing works
Miyoshi, G., Butt, S. J. B., Takebayashi, H., & Fishell, G. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1807-07.2007 · Cited by 400 · see citing works
Self-citationBortone, D., & Polleux, F. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.034 · Cited by 387 · see citing works
Neocortical Somatostatin-Expressing GABAergic Interneurons Disinhibit the Thalamorecipient Layer 4
Xu, H., Jeong, H.-Y., Tremblay, R., & Rudy, B. (2013) · Neuron · doi:10.1016/j.neuron.2012.11.004 · Cited by 366 · see citing works
Self-citationIntrinsically determined cell death of developing cortical interneurons
Southwell, D. G., Paredes, M. F., Galvao, R. P., Jones, D. L., Froemke, R. C., Sebe, J. Y., Alfaro-Cervello, C., Tang, Y., Garcia-Verdugo, J. M., Rubenstein, J. L., et al. (2012) · Nature · doi:10.1038/nature11523 · Cited by 365 · see citing works
Gil, Z., Connors, B. W., & Amitai, Y. (1999) · Neuron · doi:10.1016/s0896-6273(00)80788-6 · Cited by 362 · see citing works
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Azim, E., Jiang, J., Alstermark, B., & Jessell, T. M. (2014) · Nature · doi:10.1038/nature13021 · Cited by 355 · see citing works
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Zhang, Y., Narayan, S., Geiman, E. J., Lanuza, G. M., Velasquez, T., Shanks, B., Akay, T., Dyck, J. R. B., Pearson, K. G., Gosgnach, S., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.027 · Cited by 350 · see citing works
Self-citationOxytocin enhances hippocampal spike transmission by modulating fast-spiking interneurons
Owen, S. F., Tuncdemir, S. N., Bader, P. L., Tirko, N. N., Fishell, G., & Tsien, R. W. (2013) · Nature · doi:10.1038/nature12330 · Cited by 339 · see citing works
Dark Rearing Alters the Development of GABAergic Transmission in Visual Cortex
Morales, B., Choi, S.-Y., & Kirkwood, A. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-18-08084.2002 · Cited by 329 · see citing works
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Sousa, V. H., Miyoshi, G., Hjerling-Leffler, J., Karayannis, T., & Fishell, G. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp038 · Cited by 328 · see citing works
Self-citationOsakada, F., Mori, T., Cetin, A. H., Marshel, J. H., Virgen, B., & Callaway, E. M. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.005 · Cited by 314 · see citing works
Self-citationMechanisms of Synapse Assembly and Disassembly
Goda, Y., & Davis, G. W. (2003) · Neuron · doi:10.1016/s0896-6273(03)00608-1 · Cited by 297 · see citing works
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De Marco García, N. V., Karayannis, T., & Fishell, G. (2011) · Nature · doi:10.1038/nature09865 · Cited by 294 · see citing works
Self-citationEntorhinal cortex of the rat: Organization of intrinsic connections
Dolorfo, C. L., & Amaral, D. G. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980817)398:1 · Cited by 268 · see citing works
Early Gamma Oscillations Synchronize Developing Thalamus and Cortex
Minlebaev, M., Colonnese, M., Tsintsadze, T., Sirota, A., & Khazipov, R. (2011) · Science · doi:10.1126/science.1210574 · Cited by 257 · see citing works
Miyoshi, G., & Fishell, G. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq155 · Cited by 230 · see citing works
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Batista‐Brito, R., & Fishell, G. (2009) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(09)01203-4 · Cited by 223 · see citing works
Self-citationSun, Y., Nguyen, A. Q., Nguyen, J. P., Le, L., Saur, D., Choi, J., Callaway, E. M., & Xu, X. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.02.030 · Cited by 218 · see citing works
Self-citationZhang, Z. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00855.2003 · Cited by 210 · see citing works
Kruglikov, I., & Rudy, B. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.024 · Cited by 209 · see citing works
Self-citationIntegration of GABAergic interneurons into cortical cell assemblies: lessons from embryos and adults
Bartolini, G., Ciceri, G., & Marín, O. (2013) · Neuron · doi:10.1016/j.neuron.2013.08.014 · Cited by 185 · see citing works
Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission
Karayannis, T., Au, E., Patel, J. C., Kruglikov, I., Markx, S., Delorme, R., Héron, D., Salomon, D., Glessner, J., Restituito, S., et al. (2014) · Nature · doi:10.1038/nature13248 · Cited by 183 · see citing works
Self-citationCoordinated developmental recruitment of latent fast spiking interneurons in layer IV barrel cortex
Daw, M. I., Ashby, M. C., & Isaac, J. T. R. (2007) · Nature Neuroscience · doi:10.1038/nn1866 · Cited by 174 · see citing works
Molecular Mechanisms of Synaptic Specificity in Developing Neural Circuits
Williams, M. E., de Wit, J., & Ghosh, A. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.007 · Cited by 173 · see citing works
Major Effects of Sensory Experiences on the Neocortical Inhibitory Circuits
Jiao, Y., Zhang, C., Yanagawa, Y., & Sun, Q. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2478-06.2006 · Cited by 168 · see citing works
Pioneer GABA Cells Comprise a Subpopulation of Hub Neurons in the Developing Hippocampus
Picardo, M. A., Guigue, P., Bonifazi, P., Batista-Brito, R., Allene, C., Ribas, A., Fishell, G., Baude, A., & Cossart, R. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.018 · Cited by 167 · see citing works
Self-citationNeske, G. T., Patrick, S. L., & Connors, B. W. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2279-14.2015 · Cited by 167 · see citing works
Functional Synaptic Projections onto Subplate Neurons in Neonatal Rat Somatosensory Cortex
Hanganu, I. L., Kilb, W., & Luhmann, H. J. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-16-07165.2002 · Cited by 159 · see citing works
Short-Term Dynamics of Thalamocortical and Intracortical Synapses Onto Layer 6 Neurons in Neocortex
Beierlein, M., & Connors, B. W. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.4.1924 · Cited by 152 · see citing works
Close, J., Xu, H., De Marco García, N., Batista-Brito, R., Rossignol, E., Rudy, B., & Fishell, G. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3583-12.2012 · Cited by 141 · see citing works
Self-citationSeidler, B., Schmidt, A., Mayr, U., Nakhai, H., Schmid, R. M., Schneider, G., & Saur, D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800487105 · Cited by 136 · see citing works
Cerebral cortical development in rodents and primates
Molnár, Z., & Clowry, G. J. (2012) · Progress in brain research · doi:10.1016/b978-0-444-53860-4.00003-9 · Cited by 130 · see citing works
Early depolarizing GABA controls critical-period plasticity in the rat visual cortex
Deidda, G., Allegra, M., Cerri, C., Naskar, S., Bony, G., Zunino, G., Bozzi, Y., Caleo, M., & Cancedda, L. (2015) · Nature Neuroscience · doi:10.1038/nn.3890 · Cited by 120 · see citing works
Hu, H., Cavendish, J. Z., & Agmon, A. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00195 · Cited by 120 · see citing works
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De Marco García, N. V., Priya, R., Tuncdemir, S. N., Fishell, G., & Karayannis, T. (2015) · Nature Neuroscience · doi:10.1038/nn.3946 · Cited by 117 · see citing works
Self-citationNarboux‐Nême, N., Evrard, A., Férézou, I., Erzurumlu, R. S., Kaeser, P. S., Lainé, J., Rossier, J., Ropert, N., Südhof, T. C., & Gaspar, P. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0343-12.2012 · Cited by 94 · see citing works
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Agmon, A., Hollrigel, G. S., & O’Dowd, D. K. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-15-04684.1996 · Cited by 91 · see citing works
Li, Y., Stam, F. J., Aimone, J. B., Goulding, M., Callaway, E. M., & Gage, F. H. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1306912110 · Cited by 88 · see citing works
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Long, M. A., Cruikshank, S. J., Jutras, M. J., & Connors, B. W. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0375-05.2005 · Cited by 83 · see citing works
Pangratz-Fuehrer, S., & Hestrin, S. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6655-10.2011 · Cited by 83 · see citing works
A GABAergic projection from the zona incerta to cortex promotes cortical neuron development
Chen, J., & Kriegstein, A. R. (2015) · Science · doi:10.1126/science.aac6472 · Cited by 82 · see citing works
Emergence of cortical inhibition by coordinated sensory-driven plasticity at distinct synaptic loci
Chittajallu, R., & Isaac, J. T. R. (2010) · Nature Neuroscience · doi:10.1038/nn.2639 · Cited by 81 · see citing works
Lazarus, M. S., & Huang, Z. J. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00729.2010 · Cited by 77 · see citing works
Molnár, Z., Kurotani, T., Higashi, S., Yamamoto, N., & Toyama, K. (2003) · Brain Research Bulletin · doi:10.1016/s0361-9230(03)00061-3 · Cited by 69 · see citing works
Cossart, R. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.12.002 · Cited by 57 · see citing works
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Takesian, A. E., Kotak, V. C., Sharma, N., & Sanes, D. H. (2013) · Journal of Neurophysiology · doi:10.1152/jn.00182.2013 · Cited by 48 · see citing works
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Sauer, J., & Bartos, M. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4125-09.2010 · Cited by 42 · see citing works
miRNAs are Essential for the Survival and Maturation of Cortical Interneurons
Tuncdemir, S. N., Fishell, G., & Batista‐Brito, R. (2014) · Cerebral Cortex · doi:10.1093/cercor/bht426 · Cited by 22 · see citing works
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Ben-Shalom, R., Keeshen, C. M., Berrios, K. N., An, J. Y., Sanders, S. J., & Bender, K. J. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.01.009 · Cited by 288 · see citing works
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Cardin, J. A. (2018) · Trends in Neurosciences · doi:10.1016/j.tins.2018.07.015 · Cited by 254 · see citing works
Marques-Smith, A., Lyngholm, D., Kaufmann, A.-K., Stacey, J. A., Hoerder-Suabedissen, A., Becker, E. B. E., Wilson, M. C., Molnár, Z., & Butt, S. J. B. (2016) · Neuron · doi:10.1016/j.neuron.2016.01.015 · Cited by 173 · see citing works
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Che, A., Babij, R., Iannone, A. F., Fetcho, R. N., Ferrer, M., Liston, C., Fishell, G., & De Marco García, N. V. (2018) · Neuron · doi:10.1016/j.neuron.2018.06.002 · Cited by 91 · see citing works
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- Authors
- Tuncdemir, S. N., Wamsley, B., Stam, F. J., Osakada, F., Goulding, M., Callaway, E. M., Rudy, B., & Fishell, G.
- Affiliations
- New York University (US)
- Salk Institute for Biological Studies (US)
- NYU Langone Health (US)
- Corresponding author
- Fishell, Gord
- ORCID
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 89
- Issue
- 3
- Pages
- 521-535
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC4861073
- OpenAlex
- W2257395058
- Cited by
- 224
- References
- 74
- Citations by year
- 2026: 13 · 2025: 22 · 2024: 26 · 2023: 21 · 2022: 19 · 2021: 40 · 2020: 19 · 2019: 20 · 2018: 13 · 2017: 19 · 2016: 12
- FWCI
- 12.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5r01ns030989-22)
- National Institute of Mental Health (R01MH063912, MH0639123, T32MH015174, R01MH068469, R01MH071679, MH095147, R01MH095147, R37MH071679)
- National Eye Institute (EY022577, R01EY022577)
- National Institute of Neurological Disorders and Stroke (R01-NS030989, R01NS086372, NS 081297, P01NS074972, NS080586, R01 NS30989, R01NS090919, NS090919, R01NS080586, NS086372, R01NS081297, T32NS086750)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- somatostatin interneurons, parvalbumin interneurons, thalamocortical afferents, synapse maturation, feedforward inhibition, postnatal development, pyramidal neurons
- MeSH terms
- Animals, Cerebral Cortex, Interneurons, Neural Pathways, Parvalbumins, Somatostatin, Thalamus, Pyramidal Cells, Mice
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