Cited by 166Memory and Neural MechanismsNeurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Dorsal and ventral streams: the distinct role of striatal subregions in the acquisition and performance of goal-directed actions

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Hart, Genevra, Leung, Beatrice K., Balleine, Bernard W.·2014·Neurobiology of Learning and Memory

Abstract

Considerable evidence suggests that distinct neural processes mediate the acquisition and performance of goal-directed instrumental actions. Whereas a cortical-dorsomedial striatal circuit appears critical for the acquisition of goal-directed actions, a cortical-ventral striatal circuit appears to mediate instrumental performance, particularly the motivational control of performance. Here we review evidence that these distinct mechanisms of learning and performance constitute two distinct 'streams' controlling instrumental conditioning. From this perspective, the regulation of the interaction between these 'streams' becomes a matter of considerable importance. We describe evidence that the basolateral amygdala, which is heavily interconnected with both the dorsal and ventral subregions of the striatum, coordinates this interaction providing input to the final common path to action as a critical component of the limbic-motor interface.

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Authors
Hart, G., Leung, B. K., & Balleine, B. W.
Affiliations
The University of Sydney (AU)
Corresponding author
Balleine, Bernard W.
Venue
Neurobiology of Learning and Memory
Publisher
Elsevier BV
Published
2014-02
Volume
108
Pages
104-118
ISSN
1074-7427 (ISSN-L)
OpenAlex
W2034389479
Cited by
166
References
152
Citations by year
2026: 3 · 2025: 12 · 2024: 10 · 2023: 10 · 2022: 10 · 2021: 9 · 2020: 17 · 2019: 18 · 2018: 20 · 2017: 16 · 2016: 20 · 2015: 15 · 2014: 6
FWCI
1.17
Type
journal article
Language
en
Open access
Locations
  • Neurobiology of Learning and Memory (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (5r01mh056646-04)
  • National Institute of Mental Health (MH-56646, R01MH056446)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
dorsal striatum, ventral striatum, goal-directed behavior, operant conditioning, instrumental performance, basolateral amygdala, motivational control
MeSH terms
Animals, Basal Ganglia, Brain, Conditioning, Operant, Corpus Striatum, Goals, Humans, Reward, Mice, Rats

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