Dorsal and ventral streams: the distinct role of striatal subregions in the acquisition and performance of goal-directed actions
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Considerable evidence suggests that distinct neural processes mediate the acquisition and performance of goal-directed instrumental actions. Whereas a cortical-dorsomedial striatal circuit appears critical for the acquisition of goal-directed actions, a cortical-ventral striatal circuit appears to mediate instrumental performance, particularly the motivational control of performance. Here we review evidence that these distinct mechanisms of learning and performance constitute two distinct 'streams' controlling instrumental conditioning. From this perspective, the regulation of the interaction between these 'streams' becomes a matter of considerable importance. We describe evidence that the basolateral amygdala, which is heavily interconnected with both the dorsal and ventral subregions of the striatum, coordinates this interaction providing input to the final common path to action as a critical component of the limbic-motor interface.
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The ventral striatum guides performance of goal-directed behaviors.
“The VS guides performance of goal-directed behaviors (Cardinal et al., 2002a; Yin et al., 2008; Hart et al., 2014)”
From A framework for understanding the emerging role of corticolimbic-ventral striatal networks in OCD-associated repetitive behaviors (2015) · cites this paper as Hart et al., 2014
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- Authors
- Hart, G., Leung, B. K., & Balleine, B. W.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Balleine, Bernard W.
- Venue
- Neurobiology of Learning and Memory
- Publisher
- Elsevier BV
- Published
- 2014-02
- Volume
- 108
- Pages
- 104-118
- ISSN
- 1074-7427 (ISSN-L)
- PMC
- PMC4661143
- OpenAlex
- W2034389479
- Cited by
- 166
- References
- 152
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 10 · 2023: 10 · 2022: 10 · 2021: 9 · 2020: 17 · 2019: 18 · 2018: 20 · 2017: 16 · 2016: 20 · 2015: 15 · 2014: 6
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Neurobiology of Learning and Memory (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5r01mh056646-04)
- National Institute of Mental Health (MH-56646, R01MH056446)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- dorsal striatum, ventral striatum, goal-directed behavior, operant conditioning, instrumental performance, basolateral amygdala, motivational control
- MeSH terms
- Animals, Basal Ganglia, Brain, Conditioning, Operant, Corpus Striatum, Goals, Humans, Reward, Mice, Rats
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