CoChat
Sign Up
Cited by 162Neural and Behavioral Psychology StudiesExperimental Behavioral Economics StudiesDecision-Making and Behavioral Economics

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Toward a Model of Interpersonal Trust Drawn from Neuroscience, Psychology, and Economics

Krueger, Frank, Meyer-Lindenberg, Andreas·2019·Trends in Neurosciences
DOI 10.1016/j.tins.2018.10.004
Open this paper in CoChat — free account

Abstract

Trust pervades nearly every social aspect of our daily lives, and its disruption is a significant factor in mental illness. Research in the field of neuroeconomics has gained a deeper understanding of the neuropsychoeconomic (NPE) underpinnings of trust by combining complementary methodologies from neuroscience, psychology, and economics. However, a coherent model of trust that integrates separate findings under a conceptual framework is still lacking. Here, we sketch out an integrative NPE model that explains how the interactions of psychoeconomic components engage domain-general large-scale brain networks in shaping trust behavior over time. We also point out caveats of current research approaches and outline open questions that can help guide future transdisciplinary investigations for a better understanding of the neuropsychology of trust.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.tins.2018.10.004

Cites

18 of 18 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The neural circuits of trust and loneliness are largely intertwined and share neuroanatomical pathways via the amygdala, anterior insula, medial prefrontal cortex, nucleus accumbens, and temporoparietal junction.

    “the neural circuits of trust and loneliness are largely intertwined and share neuroanatomical pathways via the amygdala, the anterior insula (AI), the medial prefrontal cortex (mPFC), the nucleus accumbens (NAcc), and the temporoparietal junction (TPJ).[ 6 , 14 , 15 , 16 , 17 ]”

    From Loneliness and the Social Brain: How Perceived Social Isolation Impairs Human Interactions (2021) · cites this paper as [15]

  • High-lonely participants did not differ from low-lonely participants in game conditions per se but showed a blunted differentiation between trust- and risk-related trials in the left amygdala, left anterior insula, and right nucleus accumbens.

    “Results revealed that HL participants did not differ from LL participants in game conditions per se (all p cor > 0.072) but rather showed a blunted differentiation (i.e., smaller activity increase) between trust‐ and risk‐related trials in brain regions associated with the evaluation of trustworthiness, risk of betrayal, and reward anticipation.[ 15 ]”

    From Loneliness and the Social Brain: How Perceived Social Isolation Impairs Human Interactions (2021) · cites this paper as [15]

  • The main analyses of fMRI data focused on independently defined brain regions (ROIs) known to be involved in motivational, affective, and cognitive processes during the trust game.

    “The main analyses of fMRI data focused on independently defined brain regions (ROIs) known to be involved in motivational, affective, and cognitive processes during the trust game consisting of the bilateral amygdala, AI, mPFC, and TPJ[ 15 ]”

    From Loneliness and the Social Brain: How Perceived Social Isolation Impairs Human Interactions (2021) · cites this paper as [15]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 47

  1. Unoka, 2009, Trust game reveals restricted interpersonal transactions in patients with borderline personality disorder, J. Pers. Disord., 23, 399, 10.1521/pedi.2009.23.4.399 · DOI
  2. Fett, 2012, To trust or not to trust: the dynamics of social interaction in psychosis, Brain, 135, 976, 10.1093/brain/awr359 · DOI
  3. Seppanen, 2007, Measuring inter-organizational trust – a critical review of the empirical research in 1990–2003, Ind. Mark. Manage, 36, 249, 10.1016/j.indmarman.2005.09.003 · DOI
  4. Fehr, 2009, On the economics and biology of trust, J. Eur. Econ. Assoc., 7, 235, 10.1162/JEEA.2009.7.2-3.235 · DOI · Paper page
  5. Tzieropoulos, 2013, The trust game in neuroscience: a short review, Soc. Neurosci., 8, 407, 10.1080/17470919.2013.832375 · DOI
  6. Declerck, 2013, When do people cooperate? The neuroeconomics of prosocial decision making, Brain Cogn., 81, 95, 10.1016/j.bandc.2012.09.009 · DOI
  7. Riedl, 2012, The biology of trust: integrating evidence from genetics, endocrinology, and functional brain imaging, J. Neurosci. Psychol. Econ., 5, 63, 10.1037/a0026318 · DOI
  8. Bellucci, 2018, The role of the anterior insula in social norm compliance and enforcement: evidence from coordinate-based and functional connectivity meta-analyses, Neurosci. Biobehav. Rev., 92, 378, 10.1016/j.neubiorev.2018.06.024 · DOI
  9. Bellucci, 2017, Neural signatures of trust in reciprocity: a coordinate-based meta-analysis, Hum. Brain Mapp., 38, 1233, 10.1002/hbm.23451 · DOI · Paper page
  10. Camerer, 1988, Experimental tests of a sequential equilibrium reputation model, Econometrica, 56, 1, 10.2307/1911840 · DOI · Paper page
  11. Berg, 1995, Trust, reciprocity, and social-history, Games Econ. Behav., 10, 122, 10.1006/game.1995.1027 · DOI · Paper page
  12. Ikemoto, 2010, Brain reward circuitry beyond the mesolimbic dopamine system: a neurobiological theory, Neurosci. Biobehav. Rev., 35, 129, 10.1016/j.neubiorev.2010.02.001 · DOI · Paper page
  13. Hare, 2009, Self-control in decision-making involves modulation of the vmPFC valuation system, Science, 324, 646, 10.1126/science.1168450 · DOI · Paper page
  14. Koenigs, 2007, Irrational economic decision-making after ventromedial prefrontal damage: evidence from the Ultimatum Game, J. Neurosci., 27, 951, 10.1523/JNEUROSCI.4606-06.2007 · DOI
  15. Moretto, 2013, Investment and repayment in a trust game after ventromedial prefrontal damage, Front. Hum. Neurosci., 7, 593, 10.3389/fnhum.2013.00593 · DOI
  16. Montague, 2002, Neural economics and the biological substrates of valuation, Neuron, 36, 265, 10.1016/S0896-6273(02)00974-1 · DOI · Paper page
  17. King-Casas, 2005, Getting to know you: reputation and trust in a two-person economic exchange, Science, 308, 78, 10.1126/science.1108062 · DOI · Paper page
  18. Fouragnan, 2013, Reputational priors magnify striatal responses to violations of trust, J. Neurosci., 33, 3602, 10.1523/JNEUROSCI.3086-12.2013 · DOI · Paper page
  19. Engell, 2007, Implicit trustworthiness decisions: automatic coding of face properties in the human amygdala, J. Cogn. Neurosci., 19, 1508, 10.1162/jocn.2007.19.9.1508 · DOI
  20. Koscik, 2011, The human amygdala is necessary for developing and expressing normal interpersonal trust, Neuropsychologia, 49, 602, 10.1016/j.neuropsychologia.2010.09.023 · DOI · Paper page
  21. van Honk, 2013, Generous economic investments after basolateral amygdala damage, Proc. Natl. Acad. Sci. U. S. A., 110, 2506, 10.1073/pnas.1217316110 · DOI
  22. Namkung, 2017, The insula: an underestimated brain area in clinical neuroscience, psychiatry, and neurology, Trends Neurosci., 40, 200, 10.1016/j.tins.2017.02.002 · DOI · Paper page
  23. Aimone, 2014, Neural signatures of betrayal aversion: an fMRI study of trust, Proc. Biol. Sci., 281
  24. Belfi, 2015, Damage to the insula is associated with abnormal interpersonal trust, Neuropsychologia, 71, 165, 10.1016/j.neuropsychologia.2015.04.003 · DOI · Paper page
  25. Bush, 2000, Cognitive and emotional influences in anterior cingulate cortex, Trends Cogn. Sci., 4, 215, 10.1016/S1364-6613(00)01483-2 · DOI · Paper page
  26. Fett, 2014, Default distrust? An fMRI investigation of the neural development of trust and cooperation, Soc. Cogn. Affect. Neurosci., 9, 395, 10.1093/scan/nss144 · DOI
  27. Miller, 2001, An integrative theory of prefrontal cortex function, Annu. Rev. Neurosci., 24, 167, 10.1146/annurev.neuro.24.1.167 · DOI · Paper page
  28. Lemmers-Jansen, 2017, Boys vs. girls: gender differences in the neural development of trust and reciprocity depend on social context, Dev. Cogn. Neurosci., 25, 235, 10.1016/j.dcn.2017.02.001 · DOI
  29. Souza, 2009, Controlled retrieval and selection of action-relevant knowledge mediated by partially overlapping regions in left ventrolateral prefrontal cortex, Neuroimage, 46, 299, 10.1016/j.neuroimage.2009.01.046 · DOI
  30. Fett, 2014, Trust and social reciprocity in adolescence – a matter of perspective-taking, J. Adolesc., 37, 175, 10.1016/j.adolescence.2013.11.011 · DOI
  31. Xiang, 2012, Computational phenotyping of two-person interactions reveals differential neural response to depth-of-thought, PLoS Comput. Biol., 8, 10.1371/journal.pcbi.1002841 · DOI
  32. McCabe, 2001, A functional imaging study of cooperation in two-person reciprocal exchange, Proc. Natl. Acad. Sci. U. S. A., 98, 11832, 10.1073/pnas.211415698 · DOI · Paper page
  33. Lewicki, 1995, Trust in relationships, Adm. Sci. Q., 5, 583
  34. Krueger, 2007, Neural correlates of trust, Proc. Natl. Acad. Sci. U. S. A., 104, 20084, 10.1073/pnas.0710103104 · DOI
  35. Hahn, 2015, How to trust a perfect stranger: predicting initial trust behavior from resting-state brain-electrical connectivity, Soc. Cogn. Affect. Neurosci., 10, 809, 10.1093/scan/nsu122 · DOI
  36. Bellucci, 2018, Functional connectivity of specific resting-state networks predicts trust and reciprocity in the trust game, Cogn. Affect. Behav. Neurosci.
  37. Johnson, 2011, Trust games: a meta-analysis, J. Econ. Psychol., 32, 865, 10.1016/j.joep.2011.05.007 · DOI
  38. Baumgartner, 2008, Oxytocin shapes the neural circuitry of trust and trust adaptation in humans, Neuron, 58, 639, 10.1016/j.neuron.2008.04.009 · DOI · Paper page
  39. Zak, 2005, Oxytocin is associated with human trustworthiness, Horm. Behav., 48, 522, 10.1016/j.yhbeh.2005.07.009 · DOI · Paper page
  40. Cesarini, 2008, Heritability of cooperative behavior in the trust game, Proc. Natl. Acad. Sci. U. S. A., 105, 3721, 10.1073/pnas.0710069105 · DOI · Paper page
  41. Reimann, 2017, Trust is heritable, whereas distrust is not, Proc. Natl. Acad. Sci. U. S. A., 114, 7007, 10.1073/pnas.1617132114 · DOI
  42. Apicella, 2010, No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences, PLoS One, 5, 10.1371/journal.pone.0011153 · DOI
  43. Zubeldia-Brenner, 2016, Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord, J. Neuroendocrinol., 28, 10.1111/jne.12401 · DOI
  44. Carre, 2014, Testosterone responses to competition predict decreased trust ratings of emotionally neutral faces, Psychoneuroendocrinology, 49, 79, 10.1016/j.psyneuen.2014.06.011 · DOI
  45. Hareli, 2009, Emotional versus neutral expressions and perceptions of social dominance and submissiveness, Emotion, 9, 378, 10.1037/a0015958 · DOI
  46. Buskens, 2016, Testosterone administration moderates effect of social environment on trust in women depending on second-to-fourth digit ratio, Sci. Rep., 6, 10.1038/srep27655 · DOI
  47. Bos, 2012, The neural mechanisms by which testosterone acts on interpersonal trust, Neuroimage, 61, 730, 10.1016/j.neuroimage.2012.04.002 · DOI

Cited by

Sorted by citations

Metadata

Authors
Krueger, F., & Meyer-Lindenberg, A.
Venue
Trends in Neurosciences
Publisher
Elsevier BV
Published
2019-02
Volume
42
Issue
2
Pages
92-101
ISSN
0166-2236 (ISSN-L)
DOI
10.1016/j.tins.2018.10.004
OpenAlex
W2898167071
Cited by
162
References
18
Citations by year
2026: 16 · 2025: 25 · 2024: 27 · 2023: 26 · 2022: 17 · 2021: 31 · 2020: 14 · 2019: 5
FWCI
1.59
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Trends in Neurosciences (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Experimental Behavioral Economics Studies
  • Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
Keywords
interpersonal trust, neuroeconomics, trust behavior, large-scale brain networks, mental illness, transdisciplinary model
MeSH terms
Interdisciplinary Research, Brain, Games, Experimental, Humans, Interpersonal Relations, Reward, Trust

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review