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Polymeric Systems for Bioprinting
Abstract
Bioprinting is rapidly being adopted as a major method for fabricating tissue engineering constructs. Through the precise deposition of cell- and bioactive molecule-laden materials, bioprinting offers researchers a means to create biological constructs with enhanced spatial complexity that more closely mimics native tissue. The vast majority of materials used in bioprinting have been polymers due to their suitability toward resembling the cellular environment and the variety of methods available to process polymeric systems in ambient or relatively mild chemical and environmental conditions. In this review, we will discuss in detail the wide variety of natural and synthetic polymers that have been employed as inks in bioprinting. We will review recent bioprinting innovations, such as increasing architectural complexity and cell viability in heterogeneous tissue constructs, which allow for the investigation of biological questions that could not be addressed before. We will also survey nascent fields of study that promise to further advance the development of novel biofabrication technologies in the field, such as 4D bioprinting and the inclusion of nanomaterials. To conclude, we will examine some of the necessary steps that must take place to bring this technology to commercial markets and facilitate its use in clinical therapies.
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Cites
Additive manufacturing (3D printing): A review of materials, methods, applications and challenges
Ngo, T. D., Kashani, A., Imbalzano, G., Nguyen, K. T. Q., & Hui, D. (2018) · Composites Part B: Engineering · doi:10.1016/j.compositesb.2018.02.012 · Cited by 8,431
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels
Yue, K., Trujillo-de Santiago, G., Alvarez, M. M., Tamayol, A., Annabi, N., & Khademhosseini, A. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.08.045 · Cited by 3,146
Sydney Gladman, A., Matsumoto, E. A., Nuzzo, R. G., Mahadevan, L., & Lewis, J. A. (2016) · Nature Materials · doi:10.1038/nmat4544 · Cited by 3,027
On the mechanisms of biocompatibility
Williams, D. F. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.023 · Cited by 2,772
Polymeric systems for controlled drug release
Uhrich, K. E., Cannizzaro, S. M., Langer, R. S., & Shakesheff, K. M. (1999) · Chemical Reviews · doi:10.1021/cr940351u · Cited by 2,633
Cell-laden microengineered gelatin methacrylate hydrogels
Nichol, J. W., Koshy, S. T., Bae, H., Hwang, C. M., Yamanlar, S., & Khademhosseini, A. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.064 · Cited by 2,377
Chondroitinase ABC promotes functional recovery after spinal cord injury
Bradbury, E. J., Moon, L. D. F., Popat, R. J., King, V. R., Bennett, G. S., Patel, P. N., Fawcett, J. W., & McMahon, S. B. (2002) · Nature · doi:10.1038/416636a · Cited by 2,357
Light-induced shape-memory polymers
Lendlein, A., Jiang, H., Jünger, O., & Langer, R. (2005) · Nature · doi:10.1038/nature03496 · Cited by 2,006
25th Anniversary Article: Engineering Hydrogels for Biofabrication
Malda, J., Visser, J., Melchels, F. P., Jüngst, T., Hennink, W. E., Dhert, W. J. A., Groll, J., & Hutmacher, D. W. (2013) · Advanced Materials · doi:10.1002/adma.201302042 · Cited by 1,901
3D bioprinting of collagen to rebuild components of the human heart
Lee, A., Hudson, A. R., Shiwarski, D. J., Tashman, J. W., Hinton, T. J., Yerneni, S., Bliley, J. M., Campbell, P. G., & Feinberg, A. W. (2019) · Science · doi:10.1126/science.aav9051 · Cited by 1,782
Biodegradable synthetic polymers for tissue engineering
CSIRO Molecular Science, B. 1., & Gunatillake, P. (2003) · European Cells and Materials · doi:10.22203/ecm.v005a01 · Cited by 1,765
Markstedt, K., Mantas, A., Tournier, I., Martínez Ávila, H., Hägg, D., & Gatenholm, P. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b00188 · Cited by 1,528
Tunable polymer multi-shape memory effect
Xie, T. (2010) · Nature · doi:10.1038/nature08863 · Cited by 1,380
Vroman, I., & Tighzert, L. (2009) · Materials · doi:10.3390/ma2020307 · Cited by 1,355
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Clegg, D. O., Reda, D. J., Harris, C. L., Klein, M. A., O'Dell, J. R., Hooper, M. M., Bradley, J. D., Bingham, C. O., Weisman, M. H., Jackson, C. G., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052771 · Cited by 1,329
Momeni, F., M.Mehdi Hassani.N, S., Liu, X., & Ni, J. (2017) · Materials & Design · doi:10.1016/j.matdes.2017.02.068 · Cited by 1,165
Multimaterial 4D Printing with Tailorable Shape Memory Polymers
Ge, Q., Sakhaei, A. H., Lee, H., Dunn, C. K., Fang, N. X., & Dunn, M. L. (2016) · Scientific Reports · doi:10.1038/srep31110 · Cited by 1,160
Hyaluronic acid (hyaluronan): A review
Necas, J., Bartosikova, L., Brauner, P., & Kolar, J. (2008) · Veterinární medicína · doi:10.17221/1930-vetmed · Cited by 998
Fibrin: A versatile scaffold for tissue engineering applications
Ahmed, T. A. E., Dare, E. V., & Hincke, M. (2008) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2007.0435 · Cited by 994
Wong, T. Y., Preston, L. A., & Schiller, N. L. (2000) · Annual Review of Microbiology · doi:10.1146/annurev.micro.54.1.289 · Cited by 669
Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels
Bertassoni, L. E., Cardoso, J. C., Manoharan, V., Cristino, A. L., Bhise, N. S., Araujo, W. A., Zorlutuna, P., Vrana, N. E., Ghaemmaghami, A. M., Dokmeci, M. R., et al. (2014) · Biofabrication · doi:10.1088/1758-5082/6/2/024105 · Cited by 642
Wang, Z., Abdulla, R., Parker, B., Samanipour, R., Ghosh, S., & Kim, K. (2015) · Biofabrication · doi:10.1088/1758-5090/7/4/045009 · Cited by 633
González-Henríquez, C. M., Sarabia-Vallejos, M. A., & Rodriguez-Hernandez, J. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2019.03.001 · Cited by 562
Zdrahala, R. J., & Zdrahala, I. J. (1999) · Journal of Biomaterials Applications · doi:10.1177/088532829901400104 · Cited by 540
ROS production in phagocytes: Why, when, and where?
Dupré-Crochet, S., Erard, M., & Nüβe, O. (2013) · Journal of Leukocyte Biology · doi:10.1189/jlb.1012544 · Cited by 467
Davidenko, N., Schuster, C. F., Bax, D. V., Farndale, R. W., Hamaia, S., Best, S. M., & Cameron, R. E. (2016) · Journal of Materials Science: Materials in Medicine · doi:10.1007/s10856-016-5763-9 · Cited by 454
Assessment methodologies for extrusion-based bioink printability
Gillispie, G., Prim, P., Copus, J., Fisher, J., Mikos, A. G., Yoo, J. J., Atala, A., & Lee, S. J. (2020) · Biofabrication · doi:10.1088/1758-5090/ab6f0d · Cited by 426
Self-citationpH‐Stimulated DNA Hydrogels Exhibiting Shape‐Memory Properties
Guo, W., Lu, C., Orbach, R., Wang, F., Qi, X., Cecconello, A., Seliktar, D., & Willner, I. (2015) · Advanced Materials · doi:10.1002/adma.201403702 · Cited by 388
Biodegradation of poly(lactic acid) and its nanocomposites
Fukushima, K., Abbate, C., Tabuani, D., Gennari, M., & Camino, G. (2009) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2009.07.001 · Cited by 368
Human Skin 3D Bioprinting Using Scaffold‐Free Approach
Pourchet, L. J., Thepot, A., Albouy, M., Courtial, E. J., Boher, A., Blum, L. J., & Marquette, C. A. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201601101 · Cited by 352
Zhao, Q., Topham, N., Anderson, J. M., Hiltner, A., Lodoen, G., & Payet, C. R. (1991) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820250205 · Cited by 318
pH-induced shape-memory polymers
Han, X., Dong, Z., Fan, M., Liu, Y., li, J., Wang, Y., Yuan, Q., Li, B., & Zhang, S. (2012) · Macromolecular Rapid Communications · doi:10.1002/marc.201200153 · Cited by 304
Self-citationAgar degradation by microorganisms and agar-degrading enzymes
Chi, W.-J., Chang, Y.-K., & Hong, S.-K. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4023-2 · Cited by 262
Christenson, E. M., Anderson, J. M., & Hiltner, A. (2004) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30067 · Cited by 219
Relationships between degradability of silk scaffolds and osteogenesis
Park, S.-H., Gil, E. S., Shi, H., Kim, H. J., Lee, K., & Kaplan, D. L. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.04.028 · Cited by 196
The arrival of commercial bioprinters – Towards 3D bioprinting revolution!
Choudhury, D., Anand, S., & Naing, M. W. (2024) · International Journal of Bioprinting · doi:10.18063/ijb.v4i2.139 · Cited by 189
Nan, W., Wang, W., Gao, H., & Liu, W. (2013) · Soft Matter · doi:10.1039/c2sm26918j · Cited by 121
Hacker, M. C., Klouda, L., Ma, B. B., Kretlow, J. D., & Mikos, A. G. (2008) · Biomacromolecules · doi:10.1021/bm8000414 · Cited by 104
Photoresponsive polyesters for tailorable shape memory biomaterials
Rochette, J. M., & Ashby, V. S. (2013) · Macromolecules · doi:10.1021/ma302354a · Cited by 68
Cited by
Fabrication of Biomedical Scaffolds Using Biodegradable Polymers.
Kirillova, A., Yeazel, T. R., Asheghali, D., Petersen, S. R., Dort, S., Gall, K., & Becker, M. L. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01200 · Cited by 368
Advances and prospects in biomimetic multilayered scaffolds for articular cartilage regeneration
Fu, L., Yang, Z., Gao, C., Li, H., Yuan, Z., Wang, F., Sui, X., Liu, S., & Guo, Q. (2020) · Regenerative Biomaterials · doi:10.1093/rb/rbaa042 · Cited by 65
Metadata
- Authors
- Bedell, M. L., Navara, A. M., Du, Y., Zhang, S., & Mikos, A. G.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-05-29
- Volume
- 120
- Issue
- 19
- Pages
- 10744-10792
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W3031288032
- Cited by
- 258
- References
- 39
- FWCI
- 4.15
- Type
- journal article
- Language
- en
- Open access
- closed
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