Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

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Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

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Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis

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HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation

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Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer

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