A neural circuit for spatial summation in visual cortex
Open accessAbstract
The response of cortical neurons to a sensory stimulus is modulated by the context. In the visual cortex, for example, stimulation of a pyramidal cell's receptive-field surround can attenuate the cell's response to a stimulus in the centre of its receptive field, a phenomenon called surround suppression. Whether cortical circuits contribute to surround suppression or whether the phenomenon is entirely relayed from earlier stages of visual processing is debated. Here we show that, in contrast to pyramidal cells, the response of somatostatin-expressing inhibitory neurons (SOMs) in the superficial layers of the mouse visual cortex increases with stimulation of the receptive-field surround. This difference results from the preferential excitation of SOMs by horizontal cortical axons. By perturbing the activity of SOMs, we show that these neurons contribute to pyramidal cells' surround suppression. These results establish a cortical circuit for surround suppression and attribute a particular function to a genetically defined type of inhibitory neuron.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
FS cells have low input resistance and a very fast time constant, perhaps due in part to developmentally regulated TASK-3 leak K+ channels.
“Low input resistance, and very fast time constant perhaps due in part to the developmentally-regulated expression of TASK-3 leak K+ channels3,4”
From GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits (2016) · cites this paper as [4]
The 'Different size tuning of distinct neurons' section describes fast-spiking inhibitory neurons and the thin spikes of parvalbumin neurons, but does not report their input resistance or membrane time constant. Searches for TASK-3 and those electrical properties found no passage addressing developmentally regulated TASK-3 channels or the proposed explanation. (LLM, conf=0.76)
Experimental — accuracy not yet measuredSst interneurons show very little interconnectivity despite overlapping axonal and dendritic domains with other Sst cells.
“On the other hand, Sst INs, despite having axonal plexus overlapping with dendritic domains of other Sst cells show very little interconnectivity (Adesnik et al., 2012; Dennison-Cavanagh et al., 1993; Gibson et al., 1999; Pfeffer et al., 2013)”
From GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits (2016) · cites this paper as Adesnik et al., 2012
The 'Excitation of SOMs by horizontal axons' section (page unavailable) reports little inhibition recorded in SOMs during stimulation of horizontal projections, but does not identify the source of that inhibition or measure SOM-to-SOM connectivity. Searches for SOM-to-SOM connections and overlapping axonal and dendritic domains found no passage addressing those claims. (LLM, conf=0.72)
Experimental — accuracy not yet measuredSOM+ MCs in other layers receive facilitating excitatory inputs from local principal neurons in both S1 and V1.
“SOM+ MCs in other layers are known to receive facilitating excitatory inputs from local principal neurons in both S162,63 and V129,64.”
From Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas (2019) · cites this paper as [64]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Millisecond-timescale, genetically targeted optical control of neural activity
Boyden, E. S., Zhang, F., Bamberg, E., Nagel, G., & Deisseroth, K. A. (2005) · Nature Neuroscience · doi:10.1038/nn1525 · Cited by 4,831 · see citing works
RECEPTIVE FIELDS AND FUNCTIONAL ARCHITECTURE IN TWO NONSTRIATE VISUAL AREAS (18 AND 19) OF THE CAT
Hubel, D. H., & Wiesel, T. N. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.2.229 · Cited by 2,615 · see citing works
Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex
McCormick, D. A., Connors, B. W., Lighthall, J. W., & Prince, D. A. (1985) · Journal of Neurophysiology · doi:10.1152/jn.1985.54.4.782 · Cited by 1,935 · see citing works
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex
Taniguchi, H., He, M., Wu, P., Kim, S., Paik, R., Sugino, K., Kvitsani, D., Fu, Y., Lu, J., Lin, Y., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.026 · Cited by 1,828 · see citing works
Self-citationGABAergic cell subtypes and their synaptic connections in rat frontal cortex
Kawaguchi, Y. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.6.476 · Cited by 1,416 · see citing works
High-performance genetically targetable optical neural silencing by light-driven proton pumps
Chow, B. Y., Han, X., Dobry, A. S., Qian, X., Chuong, A. S., Li, M., Henninger, M. A., Belfort, G. M., Lin, Y., Monahan, P. E., et al. (2010) · Nature · doi:10.1038/nature08652 · Cited by 1,188 · see citing works
Highly selective receptive fields in mouse visual cortex
Niell, C. M., & Stryker, M. P. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.0623-08.2008 · Cited by 1,081 · see citing works
Neuronal responses to static texture patterns in area V1 of the alert macaque monkey
Knierim, J. J., & Essen, D. C. V. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.67.4.961 · Cited by 1,052 · see citing works
The subcellular organization of neocortical excitatory connections
Petreanu, L., Mao, T., Sternson, S. M., & Svoboda, K. (2009) · Nature · doi:10.1038/nature07709 · Cited by 1,047 · see citing works
Molecular and Cellular Approaches for Diversifying and Extending Optogenetics
Gradinaru, V., Zhang, F., Ramakrishnan, C., Mattis, J., Prakash, R., Diester, I., Goshen, I., Thompson, K. R., & Deisseroth, K. A. (2010) · Cell · doi:10.1016/j.cell.2010.02.037 · Cited by 999 · see citing works
The neurophysiology of figure-ground segregation in primary visual cortex
Lamme, V. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-02-01605.1995 · Cited by 946 · see citing works
Lateral inhibition between orientation detectors in the cat's visual cortex
Blakemore, C. B., & Tobin, E. (1972) · Experimental Brain Research · doi:10.1007/bf00234129 · Cited by 703 · see citing works
Kondo, M. A., Tajinda, K., Colantuoni, C., Hiyama, H., Seshadri, S., Huang, B., Pou, S., Furukori, K., Hookway, C., Peled, H. J., et al. (2012) · Cited by 655 · see citing works
Allman, J. M., Miezin, F. M., & McGuinness, E. R. (1985) · Perception · doi:10.1068/p140105 · Cited by 635 · see citing works
Atasoy, D., Aponte, Y., Su, H. H., & Sternson, S. M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1954-08.2008 · Cited by 614 · see citing works
Contrast's effect on spatial summation by macaque V1 neurons
Sceniak, M. P., Ringach, D. L., Hawken, M. J., & Shapley, R. M. (1999) · Nature Neuroscience · doi:10.1038/11197 · Cited by 608 · see citing works
Chattopadhyaya, B., Di Cristo, G., Higashiyama, H., Knott, G. W., Kuhlman, S. J., Welker, E., & Huang, Z. J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1851-04.2004 · Cited by 596 · see citing works
Self-citationContrast dependence of contextual effects in primate visual cortex
Levitt, J. B., & Lund, J. S. (1997) · Nature · doi:10.1038/387073a0 · Cited by 510 · see citing works
Area map of mouse visual cortex
Wang, Q., & Burkhalter, A. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21286 · Cited by 498 · see citing works
Length and width tuning of neurons in the cat's primary visual cortex
DeAngelis, G. C., Freeman, R. D., & Ohzawa, I. (1994) · Journal of Neurophysiology · doi:10.1152/jn.1994.71.1.347 · Cited by 475 · see citing works
Inhibitory Stabilization of the Cortical Network Underlies Visual Surround Suppression
Ozeki, H., Finn, I. M., Schaffer, E., Miller, K. D., & Ferster, D. (2009) · Neuron · doi:10.1016/j.neuron.2009.03.028 · Cited by 470 · see citing works
Angelucci, A., & Bressloff, P. C. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)54005-1 · Cited by 453 · see citing works
Quality Metrics to Accompany Spike Sorting of Extracellular Signals
Hill, D. N., Mehta, S. B., & Kleinfeld, D. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0971-11.2011 · Cited by 441 · see citing works
Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex
Kapfer, C., Glickfeld, L. L., Atallah, B. V., & Scanziani, M. (2007) · Nature Neuroscience · doi:10.1038/nn1909 · Cited by 427 · see citing works
Self-citationCavanaugh, J. R., Bair, W., & Movshon, J. A. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00693.2001 · Cited by 426 · see citing works
Role of Astrocytes in Neurovascular Coupling
Petzold, G. C., & Murthy, V. N. (2011) · Neuron · doi:10.1016/j.neuron.2011.08.009 · Cited by 409 · see citing works
Orientation-selective inhibition from beyond the classic visual receptive field
Nelson, J. I., & Frost, B. J. (1978) · Brain Research · doi:10.1016/0006-8993(78)90937-x · Cited by 396 · see citing works
Fee, M. S., Mitra, P. P., & Kleinfeld, D. (1996) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(96)00050-7 · Cited by 357 · see citing works
Lateral competition for cortical space by layer-specific horizontal circuits
Adesnik, H., & Scanziani, M. (2010) · Nature · doi:10.1038/nature08935 · Cited by 356 · see citing works
Self-citationSpatial integration and cortical dynamics.
Gilbert, C. D., Das, A., Ito, M., Kapadia, M., & Westheimer, G. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.2.615 · Cited by 329 · see citing works
The most numerous ganglion cell type of the mouse retina is a selective feature detector
Zhang, Y., Kim, I.-J., Sanes, J. R., & Meister, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1211547109 · Cited by 316 · see citing works
Dynamics of spatial summation in primary visual cortex of alert monkeys
Kapadia, M. K., Westheimer, G., & Gilbert, C. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.21.12073 · Cited by 303 · see citing works
Endstopped neurons in the visual cortex as a substrate for calculating curvature
Dobbins, A. C., Zucker, S. W., & Cynader, M. S. (1987) · Nature · doi:10.1038/329438a0 · Cited by 296 · see citing works
Visual Spatial Characterization of Macaque V1 Neurons
Sceniak, M. P., Hawken, M. J., & Shapley, R. M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.5.1873 · Cited by 288 · see citing works
Generation of end-inhibition in the visual cortex via interlaminar connections
Bolz, J., & Gilbert, C. D. (1986) · Nature · doi:10.1038/320362a0 · Cited by 287 · see citing works
Haider, B., Krause, M. R., Duque, A., Yu, Y., Touryan, J., Mazer, J. A., & McCormick, D. A. (2010) · Neuron · doi:10.1016/j.neuron.2009.12.005 · Cited by 263 · see citing works
Corticofugal feedback influences the generation of length tuning in the visual pathway
Murphy, P. C., & Sillito, A. M. (1987) · Nature · doi:10.1038/329727a0 · Cited by 257 · see citing works
The Suppressive Field of Neurons in Lateral Geniculate Nucleus
Bonin, V., Mante, V., & Carandini, M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3562-05.2005 · Cited by 239 · see citing works
Targeted Whole-Cell Recordings in the Mammalian Brain In Vivo
Margrie, T. W., Meyer, A. H., Caputi, A., Monyer, H., Hasan, M. T., Schaefer, A. T., Denk, W. T., & Brecht, M. (2003) · Neuron · doi:10.1016/j.neuron.2003.08.012 · Cited by 213 · see citing works
Ma, W., Liu, B., Li, Y.-T., Huang, Z. J., Zhang, L. I., & Tao, H. W. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3248-10.2010 · Cited by 212 · see citing works
Self-citationAlitto, H. J., & Usrey, W. M. (2008) · Neuron · doi:10.1016/j.neuron.2007.11.019 · Cited by 151 · see citing works
Ozeki, H., Sadakane, O., Akasaki, T., Naito, T., Shimegi, S., & Sato, H. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3852-03.2004 · Cited by 136 · see citing works
Receptive‐field properties of V1 and V2 neurons in mice and macaque monkeys
den Bergh, G. V., Zhang, B., Arckens, L., & Chino, Y. M. (2010) · The Journal of Comparative Neurology · doi:10.1002/cne.22321 · Cited by 132 · see citing works
Suppressive Surrounds and Contrast Gain in Magnocellular-Pathway Retinal Ganglion Cells of Macaque
Solomon, S. G., Lee, B. B., & Sun, H. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0821-06.2006 · Cited by 125 · see citing works
Visual Spatial Summation in Macaque Geniculocortical Afferents
Sceniak, M. P., Chatterjee, S., & Callaway, E. M. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00734.2006 · Cited by 54 · see citing works
Effects of contrast and size on orientation discrimination
Mareschal, I., & Shapley, R. M. (2003) · Vision Research · doi:10.1016/j.visres.2003.07.009 · Cited by 42 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits
Tremblay, R., Lee, S., & Rudy, B. (2016) · Neuron · doi:10.1016/j.neuron.2016.06.033 · Cited by 2,033 · see citing works
“, 2011; Xu and Callaway, 2009) and visual (Adesnik et al., 2012) cortices and forward interareal cortico-cortical connections, such as primary to secondary visual cortices (Yang et al.”
A Cortical Circuit for Gain Control by Behavioral State
Fu, Y., Tucciarone, J. M., Espinosa, J. S., Sheng, N., Darcy, D. P., Nicoll, R. A., Huang, Z. J., & Stryker, M. P. (2014) · Cell · doi:10.1016/j.cell.2014.01.050 · Cited by 937 · see citing works
“It has been reported that VIP neurons in V1 strongly inhibit SSTpositive inhibitory neurons (Pfeffer et al., 2013), whose activation results in suppression of the visual response of excitatory neurons (Adesnik et al., 2012).”
BackgroundInfluentialSelf-citationLong-range and local circuits for top-down modulation of visual cortex processing
Zhang, S., Xu, M., Kamigaki, T., Hoang Do, J. P., Chang, W.-C., Jenvay, S., Miyamichi, K., Luo, L., & Dan, Y. (2014) · Science · doi:10.1126/science.1254126 · Cited by 804 · see citing works
Predictive Processing: A Canonical Cortical Computation
Keller, G. B., & Mrsic-Flogel, T. D. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.003 · Cited by 836 · see citing works
Human brain networks function in connectome-specific harmonic waves
Atasoy, S., Donnelly, I., & Pearson, J. (2016) · Nature Communications · doi:10.1038/ncomms10340 · Cited by 381 · see citing works
Somatostatin-expressing neurons in cortical networks
Urban-Ciecko, J., & Barth, A. L. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.53 · Cited by 374 · see citing works
Cell-Type-Specific Activity in Prefrontal Cortex during Goal-Directed Behavior
Pinto, L., & Dan, Y. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.021 · Cited by 323 · see citing works
Three Types of Cortical Layer 5 Neurons That Differ in Brain-wide Connectivity and Function
Kim, E. J., Juavinett, A. L., Kyubwa, E. M., Jacobs, M. W., & Callaway, E. M. (2015) · Neuron · doi:10.1016/j.neuron.2015.11.002 · Cited by 323 · see citing works
Neural elements for predictive coding
Shipp, S. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.01792 · Cited by 340 · see citing works
Distinct inhibitory circuits orchestrate cortical beta and gamma band oscillations
Chen, G., Zhang, Y., Li, X., Zhao, X., Ye, Q., Lin, Y., Tao, H. W., Rasch, M. J., & Zhang, X. (2017) · Neuron · doi:10.1016/j.neuron.2017.11.033 · Cited by 345 · see citing works
The organization of two new cortical interneuronal circuits
Jiang, X., Wang, G., Lee, A. J., Stornetta, R. L., & Zhu, J. J. (2013) · Nature Neuroscience · doi:10.1038/nn.3305 · Cited by 338 · see citing works
Effects of locomotion extend throughout the mouse early visual system
Erisken, S., Vaiceliunaite, A., Jurjut, O., Fiorini, M., Katzner, S., & Busse, L. (2014) · Current Biology · doi:10.1016/j.cub.2014.10.045 · Cited by 256 · see citing works
Visuomotor Coupling Shapes the Functional Development of Mouse Visual Cortex
Attinger, A., Wang, B., & Keller, G. B. (2017) · Cell · doi:10.1016/j.cell.2017.05.023 · Cited by 252 · see citing works
Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons
Karnani, M. M., Jackson, J., Ayzenshtat, I., Hamzehei Sichani, A., Manoocheri, K., Kim, S., & Yuste, R. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.3646-15.2016 · Cited by 236 · see citing works
Locomotion controls spatial integration in mouse visual cortex
Ayaz, A., Saleem, A. B., Schölvinck, M. L., & Carandini, M. (2013) · Current Biology · doi:10.1016/j.cub.2013.04.012 · Cited by 249 · see citing works
Delevich, K., Tucciarone, J., Huang, Z. J., & Li, B. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.4565-14.2015 · Cited by 226 · see citing works
Self-citationThe role of population structure in computations through neural dynamics
Dubreuil, A., Valente, A., Beiran, M., Mastrogiuseppe, F., & Ostojic, S. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01088-4 · Cited by 237 · see citing works
Tasks for inhibitory interneurons in intact brain circuits
Roux, L., & Buzsáki, G. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.09.011 · Cited by 218 · see citing works
Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas
Scala, F., Kobak, D., Shan, S., Bernaerts, Y., Laturnus, S., Cadwell, C. R., Hartmanis, L., Froudarakis, E., Castro, J. R., Tan, Z. H., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12058-z · Cited by 193 · see citing works
An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity
Chen, N., Sugihara, H., & Sur, M. (2015) · Nature Neuroscience · doi:10.1038/nn.4002 · Cited by 210 · see citing works
Somatostatin-Expressing Inhibitory Interneurons in Cortical Circuits
Yavorska, I., & Wehr, M. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2016.00076 · Cited by 185 · see citing works
Ji, X.-Y., Zingg, B., Mesik, L., Xiao, Z., Zhang, L. I., & Tao, H. W. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhv099 · Cited by 176 · see citing works
Neuronal circuits in barrel cortex for whisker sensory perception
Staiger, J. F., & Petersen, C. C. H. (2021) · Physiological Reviews · doi:10.1152/physrev.00019.2019 · Cited by 165 · see citing works
Nigro, M. J., Hashikawa-Yamasaki, Y., & Rudy, B. (2018) · The Journal of Neuroscience · doi:10.1523/jneurosci.2415-17.2017 · Cited by 149 · see citing works
“This form of inhibition is thought to underlie surround inhibition, and gammaband synchronization in L2/3 of the visual cortex (Adesnik et al., 2012; Veit et al., 2017).”
BackgroundMineault, P. J., Tring, E., Trachtenberg, J. T., & Ringach, D. L. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.0430-16.2016 · Cited by 148 · see citing works
Neocortical Layer 1: an elegant solution to top-down and bottom-up integration
Schuman, B., Dellal, S., Prönneke, A., Machold, R., & Rudy, B. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-100520-012117 · Cited by 148 · see citing works
Complementary networks of cortical somatostatin interneurons enforce layer specific control
Naka, A., Veit, J., Shababo, B., Chance, R. K., Risso, D., Stafford, D., Snyder, B., Egladyous, A., Chu, D., Sridharan, S., et al. (2019) · eLife · doi:10.7554/elife.43696 · Cited by 117 · see citing works
Self-citationHu, H., Cavendish, J. Z., & Agmon, A. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00195 · Cited by 120 · see citing works
Toward a Genetic Dissection of Cortical Circuits in the Mouse
Huang, Z. J. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.041 · Cited by 123 · see citing works
Self-citationInhibitory Actions Unified by Network Integration
Seybold, B. A., Phillips, E. A. K., Schreiner, C. E., & Hasenstaub, A. R. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.013 · Cited by 118 · see citing works
A disinhibitory circuit motif and flexible information routing in the brain
Wang, X.-J., & Yang, G. R. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.01.002 · Cited by 113 · see citing works
Genetic dissection of GABAergic neural circuits in mouse neocortex
Taniguchi, H. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00008 · Cited by 106 · see citing works
Self-citationOptimization of interneuron function by direct coupling of cell migration and axonal targeting
Lim, L., Pakan, J. M. P., Selten, M. M., Marques-Smith, A., Llorca, A., Bae, S. E., Rochefort, N. L., & Marín, O. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0162-9 · Cited by 93 · see citing works
Functional Access to Neuron Subclasses in Rodent and Primate Forebrain
Mehta, P., Kreeger, L., Wylie, D. C., Pattadkal, J. J., Lusignan, T., Davis, M. J., Turi, G. F., Li, W.-K., Whitmire, M. P., Chen, Y., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.02.011 · Cited by 67 · see citing works
Kaplan, E. S., Cooke, S. F., Komorowski, R. W., Chubykin, A. A., Thomazeau, A., Khibnik, L. A., Gavornik, J. P., & Bear, M. F. (2016) · eLife · doi:10.7554/elife.11450 · Cited by 77 · see citing works
Runyan, C. A., & Sur, M. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2196-12.2013 · Cited by 67 · see citing works
Response-dependent dynamics of cell-specific inhibition in cortical networks in vivo
El-Boustani, S., & Sur, M. (2014) · Nature Communications · doi:10.1038/ncomms6689 · Cited by 61 · see citing works
Cortical Control of Spatial Resolution by VIP<sup>+</sup>Interneurons
Ayzenshtat, I., Karnani, M. M., Jackson, J., & Yuste, R. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.1920-16.2016 · Cited by 50 · see citing works
Inhibitory Neurons: Vip Cells Hit the Brake on Inhibition
Pfeffer, C. K. (2014) · Current Biology · doi:10.1016/j.cub.2013.11.001 · Cited by 43 · see citing works
A cell-type-specific error-correction signal in the posterior parietal cortex
Green, J., Bruno, C. A., Traunmüller, L., Ding, J., Hrvatin, S., Wilson, D. E., Khodadad, T., Samuels, J., Greenberg, M. E., & Harvey, C. D. (2023) · Nature · doi:10.1038/s41586-023-06357-1 · Cited by 43 · see citing works
Emmenegger, V., Qi, G., Wang, H., & Feldmeyer, D. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhx352 · Cited by 26 · see citing works
El-Boustani, S., Wilson, N. R., Runyan, C. A., & Sur, M. (2014) · Nature · doi:10.1038/nature13130 · Cited by 24 · see citing works
Zhou, X., Mansori, I., Fischer, T., Witte, M., & Staiger, J. F. (2020) · Journal of Comparative Neurology · doi:10.1002/cne.24756 · Cited by 18 · see citing works
Askew, C., Intskirveli, I., & Metherate, R. (2017) · eneuro · doi:10.1523/eneuro.0192-17.2017 · Cited by 18 · see citing works
The Cooperative Neuron: Cellular Foundations of Mental Life
Phillips, W. A. (2023) · doi:10.1093/oso/9780198876984.001.0001 · Cited by 13 · see citing works
Rethinking Predictive Processing
Furutachi, S., & Hofer, S. B. (2026) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-102124-031410 · Cited by 3 · see citing works
- Authors
- Adesnik, H., Bruns, W., Taniguchi, H., Huang, Z. J., & Scanziani, M.
- Affiliations
- Howard Hughes Medical Institute (US)
- Cold Spring Harbor Laboratory (US)
- Corresponding author
- Scanziani, Massimo
- Venue
- Nature
- Published
- 2012-10
- Volume
- 490
- Issue
- 7419
- Pages
- 226-231
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC3621107
- OpenAlex
- W1965322047
- Cited by
- 702
- References
- 46
- Citations by year
- 2026: 37 · 2025: 58 · 2024: 51 · 2023: 73 · 2022: 44 · 2021: 55 · 2020: 57 · 2019: 44 · 2018: 55 · 2017: 47 · 2016: 52 · 2015: 44 · 2014: 51 · 2013: 34
- FWCI
- 21.15
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory) (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institute of Neurological Disorders and Stroke (NS069010, RC1NS069010)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- surround suppression, somatostatin interneurons, inhibitory interneurons, pyramidal neurons, receptive fields, primary visual cortex, contextual modulation, mouse visual cortex
- MeSH terms
- Animals, Axons, Visual Cortex, Pyramidal Cells, Mice, Retinal Neurons, Postsynaptic Potential Summation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
