Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
the European Alzheimer's Disease Initiative Investigators, Lambert, Jean-Charles, Heath, Simon, Even, Gael, Campion, Dominique, Sleegers, Kristel, Hiltunen, Mikko, Combarros, Onofre +43 more·2009·Nature Genetics
DOI 10.1038/ng.439
Cited by (254)
Items 101–200 of 254
- Retinal vascular biomarkers for early detection and monitoring of Alzheimer’s diseaseFrost, S, Kanagasingam, Y, Sohrabi, H, Vignarajan, J, Bourgeat, P, Salvado, O, Villemagne, V, Rowe, C C, Lance Macaulay, S, Szoeke, C et al. · 2013 · Translational Psychiatry
- Glial activation and inflammation along the Alzheimer’s disease continuumNordengen, Kaja, Kirsebom, Bjørn-Eivind, Henjum, Kristi, Selnes, Per, Gísladóttir, Berglind, Wettergreen, Marianne, Torsetnes, Silje Bøen, Grøntvedt, Gøril Rolfseng, Waterloo, Knut K., Aarsland, Dag et al. · 2019 · Journal of Neuroinflammation
- The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s diseaseKanekiyo, Takahisa, Bu, Guojun · 2014 · Frontiers in Aging Neuroscience
- Microglial genes regulating neuroinflammation in the progression of Alzheimer's diseaseVillegas-Llerena, Claudio, Phillips, Alexandra, Garcia-Reitboeck, Pablo, Hardy, John, Pocock, Jennifer M · 2016 · Current Opinion in Neurobiology
- Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulationBis, Joshua C., Jian, Xueqiu, Kunkle, Brian W., Chen, Yuning, Hamilton-Nelson, Kara L., Bush, William S., Salerno, William J., Lancour, Daniel, Ma, Yiyi, Renton, Alan E. et al. · 2020 · Molecular Psychiatry
- Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architectureZhang, Qian, Sidorenko, Julia, Couvy-Duchesne, Baptiste, Marioni, Riccardo E., Wright, Margaret J., Goate, Alison M., Marcora, Edoardo, Huang, Kuan-lin, Porter, Tenielle, Laws, Simon M. et al. · 2020 · Nature Communications
- WNT signaling in neuronal maturation and synaptogenesisRosso, Silvana B., Inestrosa, Nibaldo C. · 2013 · Frontiers in Cellular Neuroscience
- Mosaic Loss of Chromosome y in Blood Is Associated with Alzheimer DiseaseDumanski, Jan P., Lambert, Jean-Charles, Rasi, Chiara, Giedraitis, Vilmantas, Davies, Hanna, Grenier-Boley, Benjamin, Lindgren, Cecilia M., Campion, Dominique, Dufouil, Carole, Pasquier, Florence et al. · 2016 · The American Journal of Human Genetics
- CD33 Alzheimer’s risk-altering polymorphism, CD33 expression, and exon 2 splicingMalik, Manasi, Simpson, James F., Parikh, Ishita, Wilfred, Bernard R., Fardo, David W., Nelson, Peter T., Estus, Steven · 2013 · The Journal of Neuroscience
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- Genetics of familial and sporadic Alzheimer s diseasePiaceri, Irene · 2013 · Frontiers in Bioscience
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- Neurovascular Dysfunction and Faulty Amyloid -Peptide Clearance in Alzheimer DiseaseSagare, A. P., Bell, R. D., Zlokovic, B. V. · 2012 · Cold Spring Harbor Perspectives in Medicine
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- Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's diseaseBossers, Koen, Wirz, Kerstin T.S., Meerhoff, Gideon F., Essing, Anke H.W., van Dongen, Jeroen W., Houba, Pieter, Kruse, Chris G., Verhaagen, Joost, Swaab, Dick F. · 2010 · Brain
- Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individualsCorneveaux, Jason J., Myers, Amanda J., Allen, April N., Pruzin, Jeremy J., Ramirez, Manuel, Engel, Anzhelika, Nalls, Michael A., Chen, Kewei, Lee, Wendy, Chewning, Kendria et al. · 2010 · Human Molecular Genetics
- Untangling Genetic Risk for Alzheimer’s DiseasePimenova, Anna A., Raj, Towfique, Goate, Alison M. · 2018 · Biological Psychiatry
- Targeting the Synapse in Alzheimer’s DiseaseJackson, Johanna, Jambrina, Enrique, Li, Jennifer, Marston, Hugh, Menzies, Fiona, Phillips, Keith, Gilmour, Gary · 2019 · Frontiers in Neuroscience
- Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sitesBrouwers, N, Van Cauwenberghe, C, Engelborghs, S, Lambert, J-C, Bettens, K, Le Bastard, N, Pasquier, F, Montoya, A Gil, Peeters, K, Mattheijssens, M et al. · 2012 · Molecular Psychiatry
- Is Alzheimer’s disease a systemic disease?Morris, Jill K., Honea, Robyn A., Vidoni, Eric D., Swerdlow, Russell H., Burns, Jeffrey M. · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Genetic Variation and Neuroimaging Measures in Alzheimer DiseaseBiffi, Alessandro · 2010 · Archives of Neurology
- Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime?Liddelow, Shane A., Marsh, Samuel E., Stevens, Beth · 2020 · Trends in Immunology
- Genetics of Alzheimer’s disease: where we are, and where we are goingBellenguez, Céline, Grenier-Boley, Benjamin, Lambert, Jean-Charles · 2020 · Current Opinion in Neurobiology
- Alzheimer’s disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytesSekar, Shobana, McDonald, Jacquelyn, Cuyugan, Lori, Aldrich, Jessica, Kurdoglu, Ahmet, Adkins, Jonathan, Serrano, Geidy, Beach, Thomas G., Craig, David W., Valla, Jonathan et al. · 2015 · Neurobiology of Aging
- Plasma clusterin and the risk of Alzheimer diseaseSchrijvers, Elisabeth M. C. · 2011 · JAMA
- Vascular disruption and blood–brain barrier dysfunction in intracerebral hemorrhageKeep, Richard F, Zhou, Ningna, Xiang, Jianming, Andjelkovic, Anuska V, Hua, Ya, Xi, Guohua · 2014 · Fluids and Barriers of the CNS
- Gene–environment interactions in Alzheimer disease: the emerging role of epigeneticsMigliore, Lucia, Coppedè, Fabio · 2022 · Nature Reviews Neurology
- Complement in the pathogenesis of Alzheimer’s diseaseMorgan, B. Paul · 2018 · Seminars in Immunopathology
- Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer’s Disease GeneticsPodleśny-Drabiniok, Anna, Marcora, Edoardo, Goate, Alison M. · 2020 · Trends in Neurosciences
- Replication of CLU, CR1, and PICALM Associations With Alzheimer DiseaseCarrasquillo, Minerva M., Belbin, Olivia, Hunter, Talisha A., Ma, Li, Bisceglio, Gina D., Zou, Fanggeng, Crook, Julia E., Pankratz, V. Shane, Dickson, Dennis W., Graff-Radford, Neill R. et al. · 2010 · Archives of Neurology
- Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s DiseaseCioffi, Federica, Adam, Rayan Hassan Ibrahim, Broersen, Kerensa · 2019 · Journal of Alzheimer s Disease
- <i>Porphyromonas gingivalis</i>
Periodontal Infection and Its Putative Links with Alzheimer’s DiseaseSinghrao, Sim K., Harding, Alice, Poole, Sophie, Kesavalu, Lakshmyya, Crean, StJohn · 2015 · Mediators of Inflammation
- Genome-wide association study of the rate of cognitive decline in Alzheimer’s diseaseSherva, Richard, Tripodis, Yorghos, Bennett, David A., Chibnik, Lori B., Crane, Paul K., de Jager, Philip L., Farrer, Lindsay A., Saykin, Andrew J., Shulman, Joshua M., Naj, Adam et al. · 2014 · Alzheimer's & Dementia
- Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and diseaseWes, Paul D., Holtman, Inge R., Boddeke, Erik W.G.M., Möller, Thomas, Eggen, Bart J.L. · 2016 · Glia
- Psychedelic N,N-Dimethyltryptamine and 5-Methoxy-N,N-Dimethyltryptamine Modulate Innate and Adaptive Inflammatory Responses through the Sigma-1 Receptor of Human Monocyte-Derived Dendritic CellsSzabo, Attila, Kovacs, Attila, Frecska, Ede, Rajnavolgyi, Eva · 2014 · PLoS ONE
- Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individualsLee, Joseph H., Cheng, Rong, Barral, Sandra, Reitz, Christiane, Medrano, Martin, Lantigua, Rafael, Jiménez-Velazquez, Ivonne Z., Rogaeva, Ekaterina, St. George-Hyslop, Peter H., Mayeux, Richard · 2011 · Archives of Neurology
- Young microglia restore amyloid plaque clearance of aged microgliaDaria, Anna, Colombo, Alessio, Llovera, Gemma, Hampel, Heike, Willem, Michael, Liesz, Arthur, Haass, Christian, Tahirovic, Sabina · 2017 · The EMBO Journal
- Targeting microglia for the treatment of Alzheimer’s DiseaseWes, Paul D., Sayed, Faten A., Bard, Frédérique, Gan, Li · 2016 · Glia
- NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell dataHe, Liang, Davila-Velderrain, Jose, Sumida, Tomokazu S., Hafler, David A., Kellis, Manolis, Kulminski, Alexander M. · 2021 · Communications Biology
- Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controlsBellenguez, Céline, Charbonnier, Camille, Grenier-Boley, Benjamin, Quenez, Olivier, Le Guennec, Kilan, Nicolas, Gaël, Chauhan, Ganesh, Wallon, David, Rousseau, Stéphane, Richard, Anne Claire et al. · 2017 · Neurobiology of Aging
- TREM2 in CNS homeostasis and neurodegenerative diseasePainter, Meghan M., Atagi, Yuka, Liu, Chia-Chen, Rademakers, Rosa, Xu, Huaxi, Fryer, John D., Bu, Guojun · 2015 · Molecular Neurodegeneration
- <i>CR1</i> is associated with amyloid plaque burden and age‐related cognitive declineChibnik, Lori B., Shulman, Joshua M., Leurgans, Sue E., Schneider, Julie A., Wilson, Robert S., Tran, Dong, Aubin, Cristin, Buchman, Aron S., Heward, Christopher B., Myers, Amanda J. et al. · 2011 · Annals of Neurology
- Effect of the Mediterranean diet on cognition and brain morphology and function: a systematic review of randomized controlled trialsRadd-Vagenas, Sue, Duffy, Shantel L, Naismith, Sharon L, Brew, Bruce J, Flood, Victoria M, Fiatarone Singh, Maria A · 2018 · The American Journal of Clinical Nutrition
- Developing novel blood‐based biomarkers for Alzheimer's diseaseSnyder, Heather M., Carrillo, Maria C., Grodstein, Francine, Henriksen, Kim, Jeromin, Andreas, Lovestone, Simon, Mielke, Michelle M., O'Bryant, Sid, Sarasa, Manual, Sj⊘gren, Magnus et al. · 2014 · Alzheimer's & Dementia
- Transcriptomics Profiling of Alzheimer’s Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAsMagistri, Marco, Velmeshev, Dmitry, Makhmutova, Madina, Faghihi, Mohammad Ali · 2015 · Journal of Alzheimer's Disease
- Correlating familial Alzheimer’s disease gene mutations with clinical phenotypeRyan, Natalie S, Rossor, Martin N · 2010 · Biomarkers in Medicine
- Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementiaFerrer, Isidro · 2012 · Progress in Neurobiology
- PU.1 regulates Alzheimer’s disease-associated genes in primary human microgliaRustenhoven, Justin, Smith, Amy M., Smyth, Leon C., Jansson, Deidre, Scotter, Emma L., Swanson, Molly E. V., Aalderink, Miranda, Coppieters, Natacha, Narayan, Pritika, Handley, Renee et al. · 2018 · Molecular Neurodegeneration
- APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohortsQian, Jing, Wolters, Frank J., Beiser, Alexa, Haan, Mary, Ikram, M. Arfan, Karlawish, Jason, Langbaum, Jessica B., Neuhaus, John M., Reiman, Eric M., Roberts, J. Scott et al. · 2017 · PLOS Medicine
- The new genetic landscape of Alzheimer’s disease: from amyloid cascade to genetically driven synaptic failure hypothesis?Dourlen, Pierre, Kilinc, Devrim, Malmanche, Nicolas, Chapuis, Julien, Lambert, Jean-Charles · 2019 · Acta Neuropathologica
- A review of quality of life after predictive testing for and earlier identification of neurodegenerative diseasesPaulsen, Jane S., Nance, Martha, Kim, Ji-In, Carlozzi, Noelle E., Panegyres, Peter K., Erwin, Cheryl, Goh, Anita, McCusker, Elizabeth, Williams, Janet K. · 2013 · Progress in Neurobiology
- Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microgliaHüttenrauch, Melanie, Ogorek, Isabella, Klafki, Hans, Otto, Markus, Stadelmann, Christine, Weggen, Sascha, Wiltfang, Jens, Wirths, Oliver · 2018 · Acta Neuropathologica Communications
- Role of Phosphatidylinositol Clathrin Assembly Lymphoid-Myeloid Leukemia (PICALM) in Intracellular Amyloid Precursor Protein (APP) Processing and Amyloid Plaque PathogenesisXiao, Qingli, Gil, So-Chon, Yan, Ping, Wang, Yan, Han, Sharon, Gonzales, Ernie, Perez, Ronaldo, Cirrito, John R., Lee, Jin-Moo · 2012 · Journal of Biological Chemistry
- Wnts in adult brain: from synaptic plasticity to cognitive deficienciesOliva, Carolina A., Vargas, Jessica Y., Inestrosa, Nibaldo C. · 2013 · Frontiers in Cellular Neuroscience
- More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegenerationLane-Donovan, Courtney, Philips, Gary T., Herz, Joachim · 2014 · Neuron
- Genetics ignite focus on microglial inflammation in Alzheimer’s diseaseMalik, Manasi, Parikh, Ishita, Vasquez, Jared B., Smith, Conor, Tai, Leon, Bu, Guojun, LaDu, Mary Jo, Fardo, David W., Rebeck, G. William, Estus, Steven · 2015 · Molecular Neurodegeneration
- Prostaglandin signaling suppresses beneficial microglial function in Alzheimer’s disease modelsJohansson, Jenny U., Woodling, Nathaniel S., Wang, Qian, Panchal, Maharshi, Liang, Xibin, Trueba-Saiz, Angel, Brown, Holden D., Mhatre, Siddhita D., Loui, Taylor, Andreasson, Katrin I. · 2015 · Journal of Clinical Investigation
- Microglial TYROBP/DAP12 in Alzheimer's Disease: Transduction of Physiological and Pathological Signals Across TREM2Haure-Mirande, Jean-Vianney, Audrain, Mickael, Ehrlich, Michelle E., Gandy, Sam · 2022 · Molecular Neurodegeneration
- Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer’s diseaseFurney, S J, Simmons, A, Breen, G, Pedroso, I, Lunnon, K, Proitsi, P, Hodges, A, Powell, J, Wahlund, L-O, Kloszewska, I et al. · 2011 · Molecular Psychiatry
- Plasma levels of apolipoprotein
<scp>E</scp>
and risk of dementia in the general populationRasmussen, Katrine L., Tybjærg‐Hansen, Anne, Nordestgaard, Børge G., Frikke‐Schmidt, Ruth · 2015 · Annals of Neurology
- New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's DiseaseFuller, James P., Stavenhagen, Jeffrey B., Teeling, Jessica L. · 2014 · Frontiers in Neuroscience
- Inflammatory pathways in Alzheimer’s disease mediated by gut microbiotaQian, Xiao-hang, Song, Xiao-xuan, Liu, Xiao-li, Chen, Sheng-di, Tang, Hui-dong · 2021 · Ageing Research Reviews
- Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing studyCuyvers, Elise, De Roeck, Arne, Van den Bossche, Tobi, Van Cauwenberghe, Caroline, Bettens, Karolien, Vermeulen, Steven, Mattheijssens, Maria, Peeters, Karin, Engelborghs, Sebastiaan, Vandenbulcke, Mathieu et al. · 2015 · The Lancet Neurology
- Rare coding mutations identified by sequencing of <scp>A</scp>lzheimer disease genome‐wide association studies lociVardarajan, Badri N., Ghani, Mahdi, Kahn, Amanda, Sheikh, Stephanie, Sato, Christine, Barral, Sandra, Lee, Joseph H., Cheng, Rong, Reitz, Christiane, Lantigua, Rafael et al. · 2015 · Annals of Neurology
- Post-mortem analysis of neuroinflammatory changes in human Alzheimer’s diseaseGomez-Nicola, Diego, Boche, Delphine · 2015 · Alzheimer's Research & Therapy
- Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer’s diseaseStein, Jason L., Hua, Xue, Morra, Jonathan H., Lee, Suh, Hibar, Derrek P., Ho, April J., Leow, Alex D., Toga, Arthur W., Sul, Jae Hoon, Kang, Hyun Min et al. · 2010 · NeuroImage
- Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway AnalysisLambert, Jean-Charles, Grenier-Boley, Benjamin, Chouraki, Vincent, Heath, Simon, Zelenika, Diana, Fievet, Nathalie, Hannequin, Didier, Pasquier, Florence, Hanon, Olivier, Brice, Alexis et al. · 2010 · Journal of Alzheimer's Disease
- Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cellsHasselmann, Jonathan, Blurton‐Jones, Mathew · 2020 · Glia
- ATP-binding cassette transporter A1: From metabolism to neurodegenerationKoldamova, Radosveta, Fitz, Nicholas F., Lefterov, Iliya · 2014 · Neurobiology of Disease
- Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activityCzirr, Eva, Castello, Nicholas A., Mosher, Kira I., Castellano, Joseph M., Hinkson, Izumi V., Lucin, Kurt M., Baeza-Raja, Bernat, Ryu, Jae Kyu, Li, Lulin, Farina, Sasha N. et al. · 2017 · Journal of Experimental Medicine
- Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulationEwers, Michael, Biechele, Gloria, Suárez‐Calvet, Marc, Sacher, Christian, Blume, Tanja, Morenas‐Rodriguez, Estrella, Deming, Yuetiva, Piccio, Laura, Cruchaga, Carlos, Kleinberger, Gernot et al. · 2020 · EMBO Molecular Medicine
- Complement receptor 1 (CR1) and Alzheimer's diseaseCrehan, Helen, Holton, Patrick, Wray, Selina, Pocock, Jennifer, Guerreiro, Rita, Hardy, John · 2012 · Immunobiology
- DAP12 stabilizes the C-terminal fragment of the triggering receptor expressed on myeloid cells-2 (TREM2) and protects against LPS-induced pro-inflammatory responseZhong, Li, Chen, Xiao-Fen, Zhang, Zhen-Lian, Wang, Zhe, Shi, Xin-Zhen, Xu, Kai, Zhang, Yun-Wu, Xu, Huaxi, Bu, Guojun · 2015 · Journal of Biological Chemistry
- Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's diseaseZhao, Liqin, Mao, Zisu, Woody, Sarah K., Brinton, Roberta D. · 2016 · Neurobiology of Aging
- The pursuit of susceptibility genes for Alzheimer's disease: progress and prospectsSleegers, Kristel, Lambert, Jean-Charles, Bertram, Lars, Cruts, Marc, Amouyel, Philippe, Van Broeckhoven, Christine · 2010 · Trends in Genetics
- Targeting innate immunity for neurodegenerative disorders of the central nervous systemAndreasson, Katrin I., Bachstetter, Adam D., Colonna, Marco, Ginhoux, Florent, Holmes, Clive, Lamb, Bruce, Landreth, Gary, Lee, Daniel C., Low, Donovan, Lynch, Marina A. et al. · 2016 · Journal of Neurochemistry
- Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK PathwayLee, Sungho, Xu, Guixiang, Jay, Taylor R., Bhatta, Sabina, Kim, Ki-Wook, Jung, Steffen, Landreth, Gary E., Ransohoff, Richard M., Lamb, Bruce T. · 2014 · The Journal of Neuroscience
- Genetic architecture of Alzheimer's diseaseNeuner, Sarah M., TCW, Julia, Goate, Alison M. · 2020 · Neurobiology of Disease
- Tracking neuroinflammation in Alzheimer’s disease: the role of positron emission tomography imagingZimmer, Eduardo Rigon, Leuzy, Antoine, Benedet, Andréa Lessa, Breitner, John, Gauthier, Serge, Rosa-Neto, Pedro · 2014 · Journal of Neuroinflammation
- APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease miceStephen, T. L., Cacciottolo, M., Balu, D., Morgan, T. E., LaDu, M. J., Finch, C. E., Pike, C. J. · 2019 · Acta Neuropathologica Communications
- Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau PathologiesGuedes, Joana R., Lao, Taotao, Cardoso, Ana L., El Khoury, Joseph · 2018 · Frontiers in Neurology
- Distribution and Expression of Picalm in Alzheimer DiseaseBaig, Shabnam, Joseph, Sally A., Tayler, Hannah, Abraham, Richard, Owen, Michael J., Williams, Julie, Kehoe, Patrick G., Love, Seth · 2010 · Journal of Neuropathology & Experimental Neurology
- Alzheimer’s disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 lociKarch, Celeste M., Ezerskiy, Lubov A., Bertelsen, Sarah, Alzheimer’s Disease Genetics Consortium (ADGC), Goate, Alison M. · 2016 · PLoS ONE
- Transcriptome-wide piRNA profiling in human brains of Alzheimer's diseaseQiu, Wenying, Guo, Xiaoyun, Lin, Xiandong, Yang, Qian, Zhang, Wanying, Zhang, Yong, Zuo, Lingjun, Zhu, Yong, Li, Chiang-Shan R., Ma, Chao et al. · 2017 · Neurobiology of Aging
- PICALM and Alzheimer’s Disease: An Update and PerspectivesAndo, Kunie, Nagaraj, Siranjeevi, Küçükali, Fahri, de Fisenne, Marie-Ange, Kosa, Andreea-Claudia, Doeraene, Emilie, Lopez Gutierrez, Lidia, Brion, Jean-Pierre, Leroy, Karelle · 2022 · Cells
- Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's diseaseKeene, C Dirk, Cudaback, Eiron, Li, Xianwu, Montine, Kathleen S, Montine, Thomas J · 2011 · Current Opinion in Neurobiology
- Neuroinflammation in Alzheimer’s disease wanes with ageHoozemans, Jeroen JM, Rozemuller, Annemieke JM, van Haastert, Elise S, Eikelenboom, Piet, van Gool, Willem A · 2011 · Journal of Neuroinflammation
- Genome-wide association analysis of age-at-onset in Alzheimer's diseaseKamboh, M I, Barmada, M M, Demirci, F Y, Minster, R L, Carrasquillo, M M, Pankratz, V S, Younkin, S G, Saykin, A J, The Alzheimer's Disease Neuroimaging Initiative, Sweet, R A et al. · 2012 · Molecular Psychiatry
- Amyloid PET in clinical practice: Its place in the multidimensional space of Alzheimer's diseaseVandenberghe, Rik, Adamczuk, Katarzyna, Dupont, Patrick, Laere, Koen Van, Chételat, Gaël · 2013 · NeuroImage: Clinical
- Blockage of CR1 prevents activation of rodent microgliaCrehan, Helen, Hardy, John, Pocock, Jennifer · 2013 · Neurobiology of Disease
- Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resiliencefor the Alzheimer’s Disease Neuroimaging Initiative, Ridge, Perry G., Karch, Celeste M., Hsu, Simon, Arano, Ivan, Teerlink, Craig C., Ebbert, Mark T. W., Gonzalez Murcia, Josue D., Farnham, James M., Damato, Anna R. et al. · 2017 · Genome Medicine
- Effect of Complement CR1 on Brain Amyloid Burden During Aging and Its Modification by APOE GenotypeThambisetty, Madhav, An, Yang, Nalls, Michael, Sojkova, Jitka, Swaminathan, Shanker, Zhou, Yun, Singleton, Andrew B., Wong, Dean F., Ferrucci, Luigi, Saykin, Andrew J. et al. · 2013 · Biological Psychiatry
- Follow-up of loci from the International Genomics of Alzheimer’s Disease Project identifies TRIP4 as a novel susceptibility geneRuiz, A, Heilmann, S, Becker, T, Hernández, I, Wagner, H, Thelen, M, Mauleón, A, Rosende-Roca, M, Bellenguez, C, Bis, J C et al. · 2014 · Translational Psychiatry
- Reelin protects against amyloid β toxicity in vivoLane-Donovan, Courtney, Philips, Gary T., Wasser, Catherine R., Durakoglugil, Murat S., Masiulis, Irene, Upadhaya, Ajeet, Pohlkamp, Theresa, Coskun, Cagil, Kotti, Tiina, Steller, Laura et al. · 2015 · Science Signaling
- Lesions without symptoms: understanding resilience to Alzheimer disease neuropathological changesGómez-Isla, Teresa, Frosch, Matthew P. · 2022 · Nature Reviews Neurology
- Analysis of the Putative Role of CR1 in Alzheimer’s Disease: Genetic Association, Expression and FunctionFonseca, Maria I., Chu, Shuhui, Pierce, Aimee L., Brubaker, William D., Hauhart, Richard E., Mastroeni, Diego, Clarke, Elizabeth V., Rogers, Joseph, Atkinson, John P., Tenner, Andrea J. · 2016 · PLOS ONE
- An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s diseaseOn Behalf of the BELNEU Consortium, De Roeck, Arne, Duchateau, Lena, Van Dongen, Jasper, Cacace, Rita, Bjerke, Maria, Van den Bossche, Tobi, Cras, Patrick, Vandenberghe, Rik, De Deyn, Peter P. et al. · 2018 · Acta Neuropathologica
- Genome-wide association reveals genetic effects on human Aβ 42 and τ protein levels in cerebrospinal fluids: a case control studyHan, Mi-Ryung, Schellenberg, Gerard D, Wang, Li-San, the Alzheimer's Disease Neuroimaging Initiative · 2010 · BMC Neurology