Cited by 1,768SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesT-cell and B-cell Immunology

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

Open access
Zheng, Meijuan, Gao, Yong, Wang, Gang, Song, Guobin, Liu, Siyu, Sun, Dandan, Xu, Yuanhong, Tian, Zhigang·2020·Cellular & Molecular Immunology

Abstract

In December 2019, a novel coronavirus was first reported in Wuhan, China. 1 It was named by the World Health Organization as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is responsible for coronavirus disease 2019 (COVID-19). Up to 28 February 2020, 79,394 cases have been confirmed according to China’s National Health Commission. Outside China, the virus has spread rapidly to over 36 countries and territories.

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Authors
Zheng, M., Gao, Y., Wang, G., Song, G., Liu, S., Sun, D., Xu, Y., & Tian, Z.
Affiliations
  • First Affiliated Hospital of Anhui Medical University (CN)
  • Anhui Medical University (CN)
  • University of Science and Technology of China (CN)
Corresponding author
  • Zheng, Meijuan
  • Xu, Yuanhong
  • Tian, Zhigang
Venue
Cellular & Molecular Immunology
Published
2020-03-19
Volume
17
Issue
5
Pages
533-535
ISSN
  • 1672-7681 (ISSN-L)
  • 2042-0226
OpenAlex
W3011508332
Cited by
1,768
References
11
Citations by year
2026: 26 · 2025: 63 · 2024: 119 · 2023: 186 · 2022: 329 · 2021: 514 · 2020: 531
Type
journal article
Language
en
Open access
Locations
  • Cellular and Molecular Immunology (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (81788101, 81771685)
  • Chinese Academy of Sciences (XDB29030000, 81788101)
  • Anhui Medical University (YJGG202002)
Topics
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
  • Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
  • Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
Keywords
COVID-19 pandemic, SARS-CoV-2, T cell exhaustion, T cell dysfunction
MeSH terms
Betacoronavirus, COVID-19, SARS-CoV-2, Antiviral Agents, Hepatitis C, Humans, Killer Cells, Natural, Pneumonia, Viral, Coronavirus Infections, Pandemics

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