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Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?

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Protein Carbonyl Measurement by a Sensitive ELISA Method

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The antioxidant paradox

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Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation

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Mechanisms of aging: an appraisal of the oxidative stress hypothesis1,2 1This article is part of a series of reviews on “Oxidative Stress and Aging.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Rajindar S. Sohal

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Short- and Long-Term Black Tea Consumption Reverses Endothelial Dysfunction in Patients With Coronary Artery Disease

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Oxidative stress in cell culture: an under‐appreciated problem?

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A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

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Detection of Superoxide in Vascular Tissue

Münzel, T. F., Afanasʹev, I. B., Kleschyov, A. L., & Harrison, D. G. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000034022.11764.ec · Cited by 281

Eosinophils Are a Major Source of Nitric Oxide-Derived Oxidants in Severe Asthma: Characterization of Pathways Available to Eosinophils for Generating Reactive Nitrogen Species

MacPherson, J. C., COMHAIR, S. A. A., ERZURUM, S. C., Klein, D. F., Lipscomb, M. F., Kavuru, M. S., Samoszuk, M. K., & Hazen, S. L. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.9.5763 · Cited by 280

Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation

Reznick, A. Z., Cross, C. E., Hu, M., Suzuki, Y., Khwaja, S., Safadi, A., Motchnik, P. A., Packer, L., & Halliwell, B. B. (1992) · Biochemical Journal · doi:10.1042/bj2860607 · Cited by 277

Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good

Halliwell, B. B., Zhao, K., & Whiteman, M. (1999) · Free Radical Research · doi:10.1080/10715769900301221 · Cited by 274

Effects of Vitamin E on Lipid Peroxidation in Healthy Persons

Meagher, E. A. (2001) · JAMA · doi:10.1001/jama.285.9.1178 · Cited by 269

The Isoprostanes: Unique Products of Arachidonic Acid Oxidation-A Review

Fam, S. S., & Morrow, J. D. (2003) · Current Medicinal Chemistry · doi:10.2174/0929867033457115 · Cited by 263

How does ascorbic acid prevent endothelial dysfunction?

May, J. M. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00269-0 · Cited by 260

SOME PROPERTIES OF THE ASCORBATE FREE RADICAL*

Bielski, B. H. J., Richter, H. W., & Chan, P. C. (1975) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1975.tb29283.x · Cited by 260

Effect of diet on cancer development: is oxidative DNA damage a biomarker?1,2 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Miral Dizdaroglu

Halliwell, B. B. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00808-0 · Cited by 258

Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

Fu, S., Davies, M. J., Stocker, R., & Dean, R. T. (1998) · Biochemical Journal · doi:10.1042/bj3330519 · Cited by 256

Action of biologically-relevant oxidizing species upon uric acid. Identification of uric acid oxidation products

Kaur, H., & Halliwell, B. B. (1990) · Chemico-Biological Interactions · doi:10.1016/0009-2797(90)90006-9 · Cited by 254

Cerebrospinal fluid F2‐isoprostane levels are increased in Alzheimer's disease

Montine, T., Markesbery, W., Morrow, J., & Roberts, L. (1998) · Annals of Neurology · doi:10.1002/ana.410440322 · Cited by 254

Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects

Nielsen, S. E., Young, J. F., Daneshvar, B., Lauridsen, S. T., Knuthsen, P., Sandström, B., & Dragsted, L. O. (1999) · British Journal Of Nutrition · doi:10.1017/s000711459900080x · Cited by 254

Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins

Ohshima, H., Friesen, M. D., Brouet, I., & Bartsch, H. (1990) · Food and Chemical Toxicology · doi:10.1016/0278-6915(90)90173-k · Cited by 250

Biochemical mechanisms accounting for the toxic action of oxygen on living organisms: The key role of superoxide dismutase

Halliwell, B. B. (1978) · Cell Biology International Reports · doi:10.1016/0309-1651(78)90032-2 · Cited by 247

Visualizing Superoxide Production in Normal and Diabetic Rat Islets of Langerhans

Bindokas, V. P., Kuznetsov, A., Sreenan, S., Polonsky, K. S., Roe, M. W., & Philipson, L. H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m206913200 · Cited by 242

Interaction of vitamin C and vitamin E during free radical stress in plasma: An ESR study

Sharma, M. K., & Buettner, G. R. (1993) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(93)90146-l · Cited by 241

Formation of the Main UV-induced Thymine Dimeric Lesions within Isolated and Cellular DNA as Measured by High Performance Liquid Chromatography-Tandem Mass Spectrometry

Douki, T., Court, M., Sauvaigo, S., Odin, F., & Cadet, J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.16.11678 · Cited by 239

Measurement of allantoin and uric acid in human body fluids. A potential index of free-radical reactions in vivo?

Grootveld, M. C., & Halliwell, B. B. (1987) · Biochemical Journal · doi:10.1042/bj2430803 · Cited by 236

Extensive tyrosine nitration in human myocardial inflammation

Kooy, N. W., Lewis, S. J., Royall, J. A., Ye, Y. Z., Kelly, D. R., & Beckman, J. S. (1997) · Critical Care Medicine · doi:10.1097/00003246-199705000-00017 · Cited by 235

Why and how should we measure oxidative DNA damage in nutritional studies? How far have we come?

Halliwell, B. B. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.5.1082 · Cited by 235

The In Vitro Cytotoxicity of Ascorbate Depends on the Culture Medium Used to Perform the Assay and Involves Hydrogen Peroxide

Clement, M., Ramalingam, J. K., Long, L. H., & Halliwell, B. B. (2001) · Antioxidants and Redox Signaling · doi:10.1089/152308601750100687 · Cited by 231

Assay of Aldehydes from Lipid Peroxidation: Gas Chromatography–Mass Spectrometry Compared to Thiobarbituric Acid

Liu, J., Yeo, H. C. H., Doniger, S. J., & Ames, B. N. (1997) · Analytical Biochemistry · doi:10.1006/abio.1996.9990 · Cited by 229

Myeloperoxidase produces nitrating oxidants in vivo

Gaut, J. P., Byun, J., Tran, H. D., Lauber, W. M., Carroll, J. A., Hotchkiss, R. S., Belaaouaj, A., & Heinecke, J. W. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15021 · Cited by 225

Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols

Hazen, S. L., Hsu, F. F., Duffin, K., & Heinecke, J. W. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.38.23080 · Cited by 221

Phenoxyl Free Radical Formation during the Oxidation of the Fluorescent Dye 2′,7′-Dichlorofluorescein by Horseradish Peroxidase

Rota, C., Fann, Y. C., & Mason, R. P. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.40.28161 · Cited by 220

Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension

Fessel, J. P., Porter, N. A., Moore, K. P., Sheller, J. R., & Roberts, L. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.252649099 · Cited by 219

Free Hydroxyl Radicals are Formed on Reaction Between the Neutrophil-Derived Species Superoxide Anion and Hypochlorous Acid

Candeias, L. P., Patel, K. B., Stratford, M. R. L., & Wardman, P. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)80394-a · Cited by 212

Scleroderma Autoantigens Are Uniquely Fragmented by Metal-catalyzed Oxidation Reactions: Implications for Pathogenesis

Casciola-Rosen, L. A., Wigley, F. M., & Rosen, A. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.1.71 · Cited by 212

ReviewIsoprostanes: Novel Bioactive Products of Lipid Peroxidation

Basu, S. (2003) · Free Radical Research · doi:10.1080/10715760310001646895 · Cited by 211

Hydrogen Peroxide in Human Urine: Implications for Antioxidant Defense and Redox Regulation

Long, L. H., Evans, P. J., & Halliwell, B. B. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1263 · Cited by 211

Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial

Huang, H.-Y., Appel, L. J., Croft, K. D., Miller, E. R., Mori, T. A., & Puddey, I. B. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.3.549 · Cited by 209

The Pickering Lecture British Hypertension Society, 10th September 2002

Harrison, D. G., Cai, H. “., Landmesser, U., & Griendling, K. K. (2003) · Journal of the Renin-Angiotensin-Aldosterone System · doi:10.3317/jraas.2003.014 · Cited by 206

Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review)

Leonarduzzi, G., Sottero, B., & Poli, G. (2002) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00222-x · Cited by 200

Fruit Polyphenolics and Brain Aging

Galli, R. L., Shukitt‐Hale, B., Youdim, K. A., & Joseph, J. A. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02089.x · Cited by 199

Endogenous oxidative damage of mtDNA

Beckman, K. B., & Ames, B. N. (1999) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(99)00007-x · Cited by 194

Identification of α-Chloro Fatty Aldehydes and Unsaturated Lysophosphatidylcholine Molecular Species in Human Atherosclerotic Lesions

Thukkani, A. K., McHowat, J., Hsu, F.-F., Brennan, M.-L., Hazen, S. L., & Ford, D. A. (2003) · Circulation · doi:10.1161/01.cir.0000104564.01539.6a · Cited by 194

F4 ‐ Isoprostanes as Specific Marker of Docosahexaenoic Acid Peroxidation in Alzheimer's Disease

Nourooz‐Zadeh, J., Liu, E. H. C., Yhlen, B., Änggåard, E. E., & Halliwell, B. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0720734.x · Cited by 187

Diastereoselective reduction of protein‐bound methionine sulfoxide by methionine sulfoxide reductase

Sharov, V. S., Ferrington, D. A., Squier, T. C., & Schöneich, C. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00888-1 · Cited by 186

A Reassessment of the Peroxynitrite Scavenging Activity of Uric Acid

Whiteman, M., Ketsawatsakul, U., & Halliwell, B. B. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04072.x · Cited by 184

Brain Regional Quantification of F-Ring and D-/E-Ring Isoprostanes and Neuroprostanes in Alzheimer’s Disease

Reich, E. E., Markesbery, W. R., Roberts, L. J., Swift, L. L., Morrow, J. D., & Montine, T. J. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63968-5 · Cited by 183

Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration

Butterfield, D. A., Debra Boyd-kimball, A., & Castegna, A. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01948.x · Cited by 183

Products of the isoprostane pathway: unique bioactive compounds and markers of lipid peroxidation

Roberts, L. J., & Morrow, J. D. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-002-8469-8 · Cited by 182

3-Bromotyrosine and 3,5-Dibromotyrosine Are Major Products of Protein Oxidation by Eosinophil Peroxidase: Potential Markers for Eosinophil-Dependent Tissue Injury in Vivo

Wu, W., Chen, Y., d'Avignon, A., & Hazen, S. L. (1999) · Biochemistry · doi:10.1021/bi982401l · Cited by 181

A carbon column-based liquid chromatography electrochemical approach to routine 8-hydroxy-2′-deoxyguanosine measurements in urine and other biologic matrices: a one-year evaluation of methods

Bogdanov, M. B., Beal, M. F., McCabe, D. R., Griffin, R. M., & Matson, W. R. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00113-6 · Cited by 179

The Reactive Adventitia

Rey, F. E., & Pagano, P. J. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000043452.30772.18 · Cited by 177

Measurement of Urinary F2-Isoprostanes as Markers of in Vivo Lipid Peroxidation—A Comparison of Enzyme Immunoassay with Gas Chromatography/Mass Spectrometry

Proudfoot, J. M., Barden, A. E., Mori, T. A., Burke, V., Croft, K. D., Beilin, L. J., & Puddey, I. B. (1999) · Analytical Biochemistry · doi:10.1006/abio.1999.4187 · Cited by 175

Vitamin C: poison, prophylactic or panacea?

Halliwell, B. B. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01418-8 · Cited by 174

Plasma F2 Isoprostanes

Sampson, M., Gopaul, N. K., Davies, I. R., Hughes, D. A., & CARRIER, M. J. (2002) · Diabetes Care · doi:10.2337/diacare.25.3.537 · Cited by 170

8-Nitroguanosine formation in viral pneumonia and its implication for pathogenesis

Akaike, T., Okamoto, S., Sawa, T., Yoshitake, J., Tamura, F., Ichimori, K., Miyazaki, K., Sasamoto, K., & Maeda, H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0235623100 · Cited by 170

Estimation of lipid peroxidation of live cells using a fluorescent probe, Diphenyl-1-pyrenylphosphine

Takahashi, M., Shibata, M., & Niki, E. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00575-5 · Cited by 170

Chemistry-based studies on oxidative DNA damage: formation, repair, and mutagenesis

Kasai, H. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00818-3 · Cited by 167

Hypochlorous Acid-Induced Base Modifications in Isolated Calf Thymus DNA

Whiteman, M., Jenner, A. M., & Halliwell, B. B. (1997) · Chemical Research in Toxicology · doi:10.1021/tx970086i · Cited by 167

Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids?

Russell, A. P., Gastaldi, G., Bobbioni-Harsch, E., Arboit, P., Gobelet, C., Dériaz, O., Golay, A., Witztum, J. L., & Giacobino, J.-P. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00875-5 · Cited by 166

Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: Evidence for neutrophil-mediated hydroxylation, nitration, and chlorination

Lamb, N. J., Gutteridge, J. M. C., Baker, C., Evans, T. W., & Quinlan, G. J. (1999) · Critical Care Medicine · doi:10.1097/00003246-199909000-00007 · Cited by 166

Oxidative Stress–Induced Iron Signaling Is Responsible for Peroxide-Dependent Oxidation of Dichlorodihydrofluorescein in Endothelial Cells

Tampo, Y., Kotamraju, S., Chitambar, C. R., Kalivendi, S. V., Keszler, Á., Joseph, J., & Kalyanaraman, B. (2003) · Circulation Research · doi:10.1161/01.res.0000048195.15637.ac · Cited by 164

Photoreduction of the fluorescent dye 2′-7′-dichlorofluorescein: a spin trapping and direct electron spin resonance study with implications for oxidative stress measurements

Marchesi, E., Rota, C., Fann, Y. C., Chignell, C. F., & Mason, R. P. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00174-9 · Cited by 162

Chemiluminescent Detection of Oxidants in Vascular Tissue

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Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F 2 -isoprostanes in human urine

Li, H., Lawson, J. A., Reilly, M. P., Adiyaman, M., Hwang, S., Rokach, J., & FitzGerald, G. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13381 · Cited by 161

Evidence for the Role of a Peroxidase Compound I-type Intermediate in the Oxidation of Glutathione, NADH, Ascorbate, and Dichlorofluorescin by Cytochrome c/H2O2

Lawrence, A. D., Jones, C. M., Wardman, P., & Burkitt, M. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300054200 · Cited by 160

Base Modification and Strand Breakage in Isolated Calf Thymus DNA and in DNA from Human Skin Epidermal Keratinocytes Exposed to Peroxynitrite or 3-Morpholinosydnonimine

Spencer, J. P. E., Wong, J., Jenner, A. M., Aruoma, O. I., Cross, C. E., & Halliwell, B. B. (1996) · Chemical Research in Toxicology · doi:10.1021/tx960084i · Cited by 159

Comet assay and early apoptosis

Choucroun, P., Gillet, D., Dorange, G., Sawicki, B., & Dewitte, J.-D. (2001) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(01)00123-3 · Cited by 158

[38] Detection of reactive nitrogen species using 2,7-dichlorodihydrfluorescein and dihydrorhodamine 123

Ischiropoulos, H., Gow, A. J., Thom, S. R., Kooy, N. W., Royall, J. A., & Crow, J. P. (1999) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(99)01100-3 · Cited by 156

Peripheral F2‐isoprostanes and F4‐neuroprostanes are not increased in Alzheimer's disease

Montine, T. J., Quinn, J. F., Milatović, D., Silbert, L. C., Dang, T. N. T., Sanchez, S. C., Terry, E. S., Roberts, L. J., Kaye, J. A., & Morrow, J. D. (2002) · Annals of Neurology · doi:10.1002/ana.10272 · Cited by 156

A hydroxyl radical–like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease

Pennathur, S., Wagner, J. D., Leeuwenburgh, C., Litwak, K. N., & Heinecke, J. W. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11194 · Cited by 153

Quantitative analysis of gene-specific DNA damage in human spermatozoa

Sawyer, D. E., Mercer, B. G., Wiklendt, A. M., & Aitken, R. J. (2003) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(03)00101-5 · Cited by 151

Analysis of free and protein-bound nitrotyrosine in human plasma by a gas chromatography/mass spectrometry method that avoids nitration artifacts

FROST, M. T., Halliwell, B. B., & Moore, K. P. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3450453 · Cited by 151

Noninvasive detection of hydroxyl radical generation in lung by diesel exhaust particles

Han, J.-Y., Takeshita, K., & Utsumi, H. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00501-3 · Cited by 148

2‐Oxo‐histidine as a novel biological marker for oxidatively modified proteins

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Detection of Superoxide and Peroxynitrite in Model Systems and Mitochondria by the Luminol Analogue L-012

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Rapid oxidation of dichlorodihydrofluorescin with heme and hemoproteins: formation of the fluorescein is independent of the generation of reactive oxygen species

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Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine

Leeuwenburgh, C., Hansen, P. A., Holloszy, J. O., & Heinecke, J. W. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00071-4 · Cited by 142

Increased carbonyl content of proteins in synovial fluid from patients with rheumatoid arthritis.

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Phagocytes Produce 5-Chlorouracil and 5-Bromouracil, Two Mutagenic Products of Myeloperoxidase, in Human Inflammatory Tissue

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Serum nitrite sensitively reflects endothelial NO formation in human forearm vasculature: evidence for biochemical assessment of the endothelial ?-arginine–NO pathway

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The cytotoxicity of dopamine may be an artefact of cell culture

Clement, M., Long, L. H., Ramalingam, J. K., & Halliwell, B. B. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00802.x · Cited by 140

Raised levels of F2-isoprostanes and prostaglandin F2α in different rheumatic diseases

Basu, S., Whiteman, M., Mattey, D. L., & Halliwell, B. B. (2001) · Annals of the Rheumatic Diseases · doi:10.1136/ard.60.6.627 · Cited by 140

Lack of effect of oral vitamin C on blood pressure, oxidative stress and endothelial function in Type II diabetes

Darko, D., Dornhorst, A., Kelly, F. J., Ritter, J. M., & Chowienczyk, P. (2002) · Clinical Science · doi:10.1042/cs1030339 · Cited by 138

Photosensitized oxidation of 2′,7′-dichlorofluorescin: singlet oxygen does not contribute to the formation of fluorescent oxidation product 2′,7′-dichlorofluorescein

Bilski, P. J., Belanger, A. G., & Chignell, C. F. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00982-6 · Cited by 138

Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients

Ghiselli, A., Laurenti, O., MATTIA, G. D., Maiani, G., & Ferro-Luzzi, A. (1992) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(92)90036-g · Cited by 138

Oxidative Stress, Inflammation, and Diabetic Vasculopathies: The Role of Alpha Tocopherol Therapy

Jialal, I., Devaraj, S., & Venugopal, S. K. (2002) · Free Radical Research · doi:10.1080/1071576021000038531 · Cited by 135

Systemic Free Radical Activation Is a Major Event Involved In Myocardial Oxidative Stress Related to Cardiopulmonary Bypass

Clermont, G., Vergely, C., Jazayeri, S., Lahet, J.-J., Goudeau, J.-J., Lecour, S., David, M., Rochette, L., & Girard, C. (2002) · Anesthesiology · doi:10.1097/00000542-200201000-00019 · Cited by 135

EPR Detection of Free Radicals in UV‐lrradiated Skin: Mouse Versus Human

Jurkiewicz, B. A., & Buettner, G. R. (1996) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1996.tb01856.x · Cited by 134

Artifact-Free Quantification of Free 3-Chlorotyrosine, 3-Bromotyrosine, and 3-Nitrotyrosine in Human Plasma by Electron Capture–Negative Chemical Ionization Gas Chromatography Mass Spectrometry and Liquid Chromatography–Electrospray Ionization Tandem Mass Spectrometry

Gaut, J. P., Byun, J., Tran, H. D., & Heinecke, J. W. (2002) · Analytical Biochemistry · doi:10.1006/abio.2001.5469 · Cited by 133

Hydroxylation of salicylate by microsomal fractions and cytochrome P-450. Lack of production of 2,3-dihydroxybenzoate unless hydroxyl radical formation is permitted

Ingelman‐Sundberg, M., Kaur, H., Terelius, Y., Persson, J. O., & Halliwell, B. B. (1991) · Biochemical Journal · doi:10.1042/bj2760753 · Cited by 132

Oxidative stress could precede endothelial dysfunction and insulin resistance in Indian Mauritians with impaired glucose metabolism

Gopaul, N. K., Manraj, M., Hébé, A., YAN, S., Johnston, A. E., CARRIER, M. J., & Änggård, E. (2001) · Diabetologia · doi:10.1007/s001250051679 · Cited by 132

Urinary isoprostane excretion is not confounded by the lipid content of the diet

Richelle, M., Turini, M. E., Guidoux, R., Tavazzi, I., Métairon, S., & Fay, L. B. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01259-4 · Cited by 127

[6] Detection of hydroxyl radicals by aromatic hydroxylation

Kaur, H., & Halliwell, B. B. (1994) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(94)33009-3 · Cited by 126

Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo. Direct evidence for a pathogenetic role of the hydroxyl radical in myocardial stunning.

Sun, J. Z., Kaur, H., Halliwell, B. B., Li, X. Y., & Bolli, R. (1993) · Circulation Research · doi:10.1161/01.res.73.3.534 · Cited by 126

Circadian variation in oxidative stress markers in healthy and type II diabetic men

Kanabrocki, E. L., Murray, D., Hermida, R. C., Scott, G. S., Bremner, W. F., Ryan, M. D., Ayala, D. E., Third, J. L. H. C., Shirazi, P. H., Nemchausky, B. A., et al. (2002) · Chronobiology International · doi:10.1081/cbi-120002914 · Cited by 126

Oxidized fat in the diet, postprandial lipaemia and cardiovascular disease

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