Neurobiology of culturally common maternal responses to infant cry
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Significance: We undertook an interdisciplinary exploration that unites evolutionary biology, neuroscience, and developmental cultural psychology. Based on extensive and detailed behavioral analyses of 684 new mothers in 11 countries and complementary functional magnetic resonance imaging (fMRI) analyses of brain responses in 43 first-time new US mothers to their own infants’ cries, 44 experienced Chinese mothers to infant cries and control emotional sounds, and 12 Italian mothers and nonmothers to generic infant cries, we identified specific behavior repertoires and specific corresponding activated brain regions in human caregivers that constitute primary responses to infant distress. This study set will appeal to scientific and general audiences because it elucidates the foundations of core parenting practices in response to infant vocal distress.
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New mothers undergo dramatic endocrinological and physiological changes supporting the establishment and maintenance of maternal caregiving, including changes throughout the central nervous system.
“New mothers themselves undergo dramatic endocrinological and physiological changes supporting the establishment and maintenance of maternal caregiving, including changes throughout the central nervous system”
From Neuromodulation of maternal circuits by oxytocin (2019) · cites this paper as Bornstein et al., 2017
Studies from human mothers show that reactivity to infant auditory cues builds over time.
“Studies from human mothers show that reactivity to infant auditory cues builds over time.”
From Neuromodulation of maternal circuits by oxytocin (2019) · cites this paper as Bornstein et al., 2017
In humans, most nursing mothers respond to baby cries with increased hypothalamic activity, rises in plasma oxytocin, comforting behaviours and occasional milk ejection.
“In humans, baby cries are a powerful signal of infant distress, and most nursing mothers respond to cries with increased hypothalamic activity, rises in the levels of plasma oxytocin, comforting behaviours towards the infant and occasional milk ejection7,8.”
From Neural circuitry for maternal oxytocin release induced by infant cries (2023) · cites this paper as [8]
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- Cunningham F, et al. (2010) Williams Obstetrics (McGraw-Hill, New York), 23rd Ed.
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Neural circuitry for maternal oxytocin release induced by infant cries
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- Authors
- Bornstein, M. H., Putnick, D. L., Rigo, P., Esposito, G., Swain, J. E., Suwalsky, J. T. D., Su, X., Du, X., Zhang, K., Cote, L. R., De Pisapia, N., & Venuti, P.
- Affiliations
- Princeton University (US)
- Nanyang Technological University (SG)
- Stony Brook University Hospital (US)
- East China Normal University (CN)
- Marymount University (US)
- Department of Psychology and Cognitive Science, University of Trento, I-38068 Trento, Italy;
- University of Trento (IT)
- Corresponding author
- Bornstein, Marc H.
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2017-10-23
- Volume
- 114
- Issue
- 45
- Pages
- E9465-E9473
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC5692572
- OpenAlex
- W2765873049
- Cited by
- 168
- References
- 183
- Citations by year
- 2026: 16 · 2025: 10 · 2024: 17 · 2023: 16 · 2022: 14 · 2021: 15 · 2020: 50 · 2019: 18 · 2018: 11 · 2016: 1
- FWCI
- 46.66
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System (Università degli Studi di Trento) (submittedVersion, other-oa)
- Padua Research Archive (University of Padova) (submittedVersion, cc-by-nc-nd)
- DR-NTU (Nanyang Technological University) (submittedVersion)
- Institutional Research Information System (Università degli Studi di Trento) (submittedVersion)
- Funders
- HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (intramural program)
- Topics
- Health Sciences › Health Professions › Pharmacy › Infant Health and Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Keywords
- infant crying, maternal responses, caregiving, primiparous women, auditory processing, supplementary motor area, inferior frontal cortex, superior temporal cortex, striatum, cross-cultural comparison, evolutionary biology
- MeSH terms
- Adult, Brain, Crying, Emotions, Female, Humans, Infant, Magnetic Resonance Imaging, Male, Maternal Behavior, Mother-Child Relations, Mothers, Neurobiology, Young Adult
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