Oxytocin modulates amygdala, insula, and inferior frontal gyrus responses to infant crying: a randomized controlled trial
Open accessAbstract
Background Oxytocin facilitates parental caregiving and mother-infant bonding and might be involved in responses to infant crying. Infant crying provides information about the physical status and mood of the infant and elicits parental proximity and caregiving. Oxytocin might modulate the activation of brain structures involved in the perception of cry sounds-specifically the insula, the amygdala, and the thalamocingulate circuit-and thereby affect responsiveness to infant crying.Method In a randomized controlled trial we investigated the influence of intranasally administered oxytocin on neural responses to infant crying with functional magnetic resonance imaging. Blood oxygenation level-dependent responses to infant crying were measured in 21 women who were administered oxytocin and 21 women who were administered a placebo.Results Induced oxytocin levels reduced, experimentally, activation in the amygdala and increased activation in the insula and inferior frontal gyrus pars triangularis.Conclusions Our findings suggest that oxytocin promotes responsiveness to infant crying by reducing activation in the neural circuitry for anxiety and aversion and increasing activation in regions involved in empathy.
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OXT altered neural responses to infant crying in samples in which the majority of women used HC.
“OXT altered neural responses to infant crying (Riem et al., 2011)”
From Hormonal contraceptives suppress oxytocin-induced brain reward responses to the partner’s face (2016) · cites this paper as Riem et al., 2011
There are studies in which OXT has produced social effects in women using HC.
“there are also studies in which OXT has produced social effects in women using HC.”
From Hormonal contraceptives suppress oxytocin-induced brain reward responses to the partner’s face (2016) · cites this paper as Riem et al., 2011
Intranasal oxytocin seems to increase empathy circuit activity in parents responding to baby cry.
“increase empathy circuit activity in parents responding to baby cry (42).”
From Neuroendocrinology of Parental Response to Baby‐Cry (2011) · cites this paper as [42]
Intranasal oxytocin seems to decrease anxiety in parents responding to baby cry.
“intranasal oxytocin seems to both decrease anxiety”
From Neuroendocrinology of Parental Response to Baby‐Cry (2011) · cites this paper as [42]
In mothers, increased amygdala activation to infant stimuli can be associated with more positive responses to one's own infant, whereas in typical adults it is interpreted as a more negative response.
“Thus, while increased activation of the amygdala to infant stimuli is interpreted as a more negative response to infants among typical adults (Riem et al., 2011), in mothers, it can be associated with more positive responses to one’s own infant (Barrett et al., 2012).”
From The maternal brain and its plasticity in humans (2016) · cites this paper as Riem et al., 2011
In these studies, administration of OT was associated with increased activations in areas related to regulation of emotion and empathy, including the ACC, the OFC, and insula.
“In fact, in these studies, administration of OT was associated with increased activations in areas related to regulation of emotion and empathy, including the ACC, the OFC, and insula (Riem et al., 2011; Riem et al., 2013).”
From The maternal brain and its plasticity in humans (2016) · cites this paper as Riem et al., 2011
Among non-parent women, administration of OT was associated with reduced responses in the amygdala to negative emotional images that were stressful, as well as stimuli that depict infants either crying or laughing.
“Among non-parent women, administration of OT was associated with reduced responses in the amygdala to negative emotional images that were stressful (Rupp et al., 2012), as well as stimuli that depict infants either crying (Riem et al., 2011) or laughing (Riem et al., 2013).”
From The maternal brain and its plasticity in humans (2016) · cites this paper as Riem et al., 2011
The amygdala activation in mothers hearing infant crying is significantly attenuated following treatment by intranasal oxytocin and is suggested to reflect the stress-reducing effects of oxytocin that may help promote responsiveness to crying infants.
“This amygdala activation is significantly attenuated following treatment by intranasal oxytocin and is suggested to reflect the stress-reducing effects of oxytocin that may help promote responsiveness to crying infants (Riem et al., 2011).”
From Oxytocin, motivation and the role of dopamine (2014) · cites this paper as Riem et al., 2011
Mothers hearing crying sounds from an infant exhibit enhanced BOLD activation within the temporal lobe and amygdala.
“Other lines of research indicate mothers hearing crying sounds from an infant exhibit enhanced BOLD activation within the temporal lobe and amygdala (Riem et al., 2011).”
From Oxytocin, motivation and the role of dopamine (2014) · cites this paper as Riem et al., 2011
Oxytocin increases activation in brain regions important for emotional processing, including the insula and inferior frontal gyrus during the perception of social stimuli.
“Some studies showed that oxytocin increases activation in brain regions important for emotional processing, including the insula and inferior frontal gryus during the perception of social stimuli (Riem et al., 2011).”
From Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal (2013) · cites this paper as Riem et al., 2011
Oxytocin decreases amygdala activation during the perception of fear-inducing or aversive social stimuli.
“Oxytocin decreases amygdala activation during the perception of fear-inducing or aversive social stimuli; it has been suggested that this explains the stress-reducing effects of oxytocin (Gamer et al., 2010;Riem et al., 2011).”
From Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal (2013) · cites this paper as Riem et al., 2011
Decreased amygdala activation might be the underlying neural mechanism of the anxiolytic effects of oxytocin.
“Because projections between the amygdala and brainstem are involved in fear behavior and arousal (LeDoux, 2000) it has been suggested that decreased amygdala activation might be the underlying neural mechanism of the anxiolytic effects of oxytocin (Gamer et al., 2010;Riem et al., 2011).”
From Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal (2013) · cites this paper as Riem et al., 2011
Cites
(1969) · Cited by 18,340 · see citing works
Advances in functional and structural MR image analysis and implementation as FSL
Smith, S. M., Jenkinson, M., Woolrich, M. W., Beckmann, C. F., Behrens, T. E. J., Johansen-Berg, H., Bannister, P. R., De Luca, M., Drobnjak, I., Flitney, D. E., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.07.051 · Cited by 13,630 · see citing works
(1978) · Medical Entomology and Zoology · Cited by 12,570 · see citing works
Jenkinson, M., Bannister, P., Brady, M., & Smith, S. (2002) · NeuroImage · doi:10.1006/nimg.2002.1132 · Cited by 11,888 · see citing works
Fast robust automated brain extraction
Smith, S. M. (2002) · Human Brain Mapping · doi:10.1002/hbm.10062 · Cited by 10,496 · see citing works
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444 · see citing works
A global optimisation method for robust affine registration of brain images
Jenkinson, M., & Smith, S. M. (2001) · Medical Image Analysis · doi:10.1016/s1361-8415(01)00036-6 · Cited by 6,806 · see citing works
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690 · see citing works
The functional architecture of human empathy
Decety, J., & Jackson, P. L. (2004) · Behavioral and Cognitive Neuroscience Reviews · doi:10.1177/1534582304267187 · Cited by 3,407 · see citing works
A unifying view of the basis of social cognition
GALLESE, V, KEYSERS, C., & RIZZOLATTI, G. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.07.002 · Cited by 2,236 · see citing works
Ainsworth, M. D. S. (1985) · PsycEXTRA Dataset · doi:10.1037/e550432011-004 · Cited by 2,140 · see citing works
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091 · see citing works
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., Gruppe, H., Mattay, V. S., Gallhofer, B., & Meyer-Lindenberg, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3984-05.2005 · Cited by 1,639 · see citing works
Imitation, empathy, and mirror neurons
Iacoboni, M. (2009) · Annual Review of Psychology · doi:10.1146/annurev.psych.60.110707.163604 · Cited by 1,606 · see citing works
The neural correlates of maternal and romantic love
Bartels, A., & Zeki, S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.11.003 · Cited by 1,448 · see citing works
Neuroendocrine perspectives on social attachment and love
Sue Carter, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00055-9 · Cited by 1,425 · see citing works
Social intelligence in the normal and autistic brain: An fMRI study
Baron‐Cohen, S., Ring, H. A., Wheelwright, S., Bullmore, E. T., Brammer, M. J., Simmons, A., & Williams, S. C. R. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00621.x · Cited by 1,320 · see citing works
Oxytocin improves “mind-reading” in humans
Domes, G., Heinrichs, M., Michel, A., Berger, C., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.015 · Cited by 1,298 · see citing works
Oxytocin shapes the neural circuitry of trust and trust adaptation in humans
Baumgartner, T., Heinrichs, M., Vonlanthen, A., Fischbacher, U., & Fehr, E. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.009 · Cited by 1,258 · see citing works
The affective organization of parenting: adaptive and maladaptive processes.
Dix, T. (1991) · Psychological bulletin · doi:10.1037/0033-2909.110.1.3 · Cited by 1,151 · see citing works
The Neuropeptide Oxytocin Regulates Parochial Altruism in Intergroup Conflict Among Humans
De Dreu, C. K. W., Greer, L. L., Handgraaf, M. J. J., Shalvi, S., Van Kleef, G. A., Baas, M., Ten Velden, F. S., Van Dijk, E., & Feith, S. W. W. (2010) · Science · doi:10.1126/science.1189047 · Cited by 1,148 · see citing works
Shamay-Tsoory, S. G. (2011) · The Neuroscientist · doi:10.1177/1073858410379268 · Cited by 1,059 · see citing works
Insel, T. R. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.005 · Cited by 1,044 · see citing works
Social Intelligence in the Normal and Autistic Brain: An fMRI Study
Baron‐Cohen, S., RING, H. A., Wheelwright, S. J., Bullmore, E. T., Brammer, M. J., Simmons, A., & Williams, S. (2002) · The MIT Press eBooks · doi:10.7551/mitpress/3077.003.0028 · Cited by 1,044 · see citing works
The triune brain in evolution: Role in paleocerebral functions
Legg, C. R. (1990) · Biological Psychology · doi:10.1016/0301-0511(90)90083-9 · Cited by 981 · see citing works
(1990) · Medical Entomology and Zoology · Cited by 919 · see citing works
Functional MRI : an introduction to methods
Jezzard, P., Matthews, P. M., & Smith, S. M. (2002) · Cited by 885 · see citing works
Statistical analysis of activation images
Worsley, K. J. (2001) · doi:10.1093/acprof:oso/9780192630711.003.0014 · Cited by 825 · see citing works
Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans
Rodrigues, S. M., Saslow, L. R., Garcia, N., John, O. P., & Keltner, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909579106 · Cited by 812 · see citing works
Feldman, R., Weller, A., Zagoory-Sharon, O., & Levine, A. (2007) · Psychological Science · doi:10.1111/j.1467-9280.2007.02010.x · Cited by 787 · see citing works
Adult attachment predicts maternal brain and oxytocin response to infant cues.
Strathearn, L., Fonagy, P., Amico, J., & Montague, P. R. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.103 · Cited by 773 · see citing works
Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans
Hurlemann, R., Patin, A., Onur, O. A., Cohen, M. X., Baumgartner, T., Metzler, S., Dziobek, I., Gallinat, J., Wagner, M., Maier, W., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5538-09.2010 · Cited by 771 · see citing works
Feldman, R., Gordon, I., Schneiderman, I., Weisman, O., & Zagoory-Sharon, O. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.01.013 · Cited by 638 · see citing works
Empathy for positive and negative emotions in the gustatory cortex
Jabbi, M., Swart, M., & Keysers, C. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.10.032 · Cited by 590 · see citing works
Balas, B., Nelson, C. A., Westerlund, A., Vogel‐Farley, V. K., Riggins, T., & Kuefner, D. (2010) · Frontiers in Human Neuroscience · doi:10.3389/neuro.09.001.2010 · Cited by 544 · see citing works
Effects of intranasal oxytocin on emotional face processing in women
Domes, G., Lischke, A., Berger, C., Grossmann, A., Hauenstein, K., Heinrichs, M., & Herpertz, S. C. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.06.016 · Cited by 521 · see citing works
Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans
Gamer, M., Zurowski, B., & Büchel, C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000985107 · Cited by 487 · see citing works
Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans
HEINRICHS, M., & DOMES, G. (2008) · Progress in brain research · doi:10.1016/s0079-6123(08)00428-7 · Cited by 479 · see citing works
Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2008) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsn004 · Cited by 474 · see citing works
Oxytocin selectively improves empathic accuracy
Bartz, J. A., Zaki, J., Bolger, N., Hollander, E., Ludwig, N. N., Kolevzon, A., & Ochsner, K. N. (2010) · Psychological Science · doi:10.1177/0956797610383439 · Cited by 442 · see citing works
Oxytocin Attenuates Affective Evaluations of Conditioned Faces and Amygdala Activity
Petrovic, P., Kalisch, R., Singer, T., & Dolan, R. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4572-07.2008 · Cited by 424 · see citing works
Oxytocin Makes a Face in Memory Familiar
Rimmele, U., Hediger, K., Heinrichs, M., & Klaver, P. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4260-08.2009 · Cited by 402 · see citing works
The signal functions of early infant crying
Soltis, J. (2004) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0400010x · Cited by 387 · see citing works
Heinrichs, M., Meinlschmidt, G., Neumann, I., Wagner, S., Kirschbaum, C., Ehlert, U., & Hellhammer, D. H. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.10.7919 · Cited by 386 · see citing works
Seifritz, E., Esposito, F., Neuhoff, J. G., Lüthi, A., Mustovic, H., Dammann, G., von Bardeleben, U., Radue, E. W., Cirillo, S., Tedeschi, G., et al. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00697-8 · Cited by 373 · see citing works
A potential role for thalamocingulate circuitry in human maternal behavior
Lorberbaum, J. P., Newman, J. D., Horwitz, A. R., Dubno, J. R., Lydiard, R. B., Hamner, M. B., Bohning, D. E., & George, M. S. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01284-7 · Cited by 359 · see citing works
Reijneveld, S. A., van der Wal, M. F., Brugman, E., Sing, R. A. H., & Verloove-Vanhorick, S. P. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17191-2 · Cited by 347 · see citing works
An Anxiolytic Action of Oxytocin is Enhanced by Estrogen in the Mouse
MCCARTHY, M. M., MCDONALD, C. H., BROOKS, P. J., & GOLDMAN, D. (1996) · Physiology & Behavior · doi:10.1016/s0031-9384(96)00212-0 · Cited by 328 · see citing works
Oxytocin improves specific recognition of positive facial expressions
Marsh, A. A., Yu, H. H., Pine, D. S., & Blair, R. J. R. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1780-4 · Cited by 321 · see citing works
Newborn Pain Cries and Vagal Tone: Parallel Changes in Response to Circumcision
Porter, F. L., Porges, S. W., & Marshall, R. E. (1988) · Child Development · doi:10.2307/1130327 · Cited by 284 · see citing works
Predicting zygosity in Norwegian twin pairs born 1915-1960
Magnus, P. M., Berg, K., & Nance, W. E. (2008) · Clinical Genetics · doi:10.1111/j.1399-0004.1983.tb02220.x · Cited by 252 · see citing works
Salonia, A., Nappi, R. E., Pontillo, M., Daverio, R., Smeraldi, A., Briganti, A., Fabbri, F., Zanni, G. E., Rigatti, P., & Montorsi, F. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.10.002 · Cited by 229 · see citing works
Gondoli, D. M., & Silverberg, S. B. (1997) · Developmental Psychology · doi:10.1037//0012-1649.33.5.861 · Cited by 227 · see citing works
Cornil, C. A., Ball, G. F., & Balthazart, J. (2006) · Brain Research · doi:10.1016/j.brainres.2006.07.098 · Cited by 223 · see citing works
Naber, F., van IJzendoorn, M. H., Deschamps, P., van Engeland, H., & Bakermans-Kranenburg, M. J. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.04.007 · Cited by 222 · see citing works
Infant crying as an elicitor of parental behavior: An examination of two models.
Murray, A. D. (1979) · Psychological Bulletin · doi:10.1037/0033-2909.86.1.191 · Cited by 217 · see citing works
An ethological analysis of human infant crying: Answering Tinbergen's four questions
Zeifman, D. M. (2001) · Developmental Psychobiology · doi:10.1002/dev.1005 · Cited by 211 · see citing works
Maternal brain response to own baby‐cry is affected by cesarean section delivery
Swain, J. E., Tasgin, E., Mayes, L. C., Feldman, R., Todd Constable, R., & Leckman, J. F. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01963.x · Cited by 206 · see citing works
Dix, T. H., Gershoff, E. T., Meunier, L. N., & Miller, P. C. (2004) · Developmental Psychology · doi:10.1037/0012-1649.40.6.1212 · Cited by 204 · see citing works
Hormonal changes during menopause
Al‐Azzawi, F., & Palacios, S. (2009) · Maturitas · doi:10.1016/j.maturitas.2009.03.009 · Cited by 182 · see citing works
Predictors of Maternal Sensitivity to Infant Distress
Leerkes, E. M. (2010) · Parenting · doi:10.1080/15295190903290840 · Cited by 177 · see citing works
Empathizing with basic emotions: Common and discrete neural substrates
Chakrabarti, B., Bullmore, E. T., & Baron‐Cohen, S. (2006) · Social Neuroscience · doi:10.1080/17470910601041317 · Cited by 158 · see citing works
Lactation and Stress: Protective Effects of Breast-feeding in Humans
Heinrichs, M., Neumann, I. D., & Ehlert, U. (2002) · Stress · doi:10.1080/1025389021000010530 · Cited by 156 · see citing works
Gondoli, D. M., & Silverberg, S. B. (1997) · Developmental Psychology · doi:10.1037/0012-1649.33.5.861 · Cited by 149 · see citing works
Beery, A. K., Lacey, E. A., & Francis, D. D. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21638 · Cited by 144 · see citing works
Leitman (2010) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2010.00019 · Cited by 137 · see citing works
Central vasopressin and oxytocin receptor distributions in two species of singing mice
Polly Campbell, A., Ophir, A. G., & Phelps, S. M. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22116 · Cited by 128 · see citing works
On the origins of background emotions: From affect synchrony to symbolic expression.
Feldman, R. (2007) · Emotion · doi:10.1037/1528-3542.7.3.601 · Cited by 125 · see citing works
The Relation between Variations in Pitch and Maternal Perceptions of Infant Crying
Zeskind, P. S., & Marshall, T. R. (1988) · Child Development · doi:10.2307/1130401 · Cited by 119 · see citing works
Riem, M. M. E., Pieper, S., Out, D., Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2011) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq035 · Cited by 113 · see citing works
Bases neuronales de la empatía
Moya‐Albiol, L., Sebastián, N. H., & Santacreu, M. C. B. (2010) · Revista de Neurología · doi:10.33588/rn.5002.2009111 · Cited by 105 · see citing works
Altemus, M. M., Roca, C., Galliven, E., Romanos, C., & Deuster, P. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.6.7596 · Cited by 104 · see citing works
The Relation between Variations in Pitch and Maternal Perceptions of Infant Crying
Zeskind, P. S., & Marshall, T. R. (1988) · Child Development · doi:10.1111/j.1467-8624.1988.tb03207.x · Cited by 103 · see citing works
Hemodynamic responses to fear and disgust-inducing pictures: an fMRI study
Stark, R. M. (2003) · International Journal of Psychophysiology · doi:10.1016/s0167-8760(03)00169-7 · Cited by 99 · see citing works
Testosterone administration modulates neural responses to crying infants in young females
Bos, P. A., Hermans, E. J., Montoya, E. R., Ramsey, N. F., & van Honk, J. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.09.013 · Cited by 99 · see citing works
Why do mothers cradle babies on their left?
Sieratzki, J. S., & Woll, B. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90813-2 · Cited by 98 · see citing works
Physiological reactivity to infant crying: a behavioral genetic study
Out, D., Pieper, S., Bakermans‐Kranenburg, M. J., & van IJzendoorn, M. H. (2010) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2010.00624.x · Cited by 85 · see citing works
Schuetze, P. A., & Zeskind, P. S. (2001) · Infancy · doi:10.1207/s15327078in0204_06 · Cited by 81 · see citing works
Steroidal/neuropeptide interactions in hypothalamus and amygdala related to social anxiety
CHOLERIS, E., DEVIDZE, N., KAVALIERS, M., & PFAFF, D. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00424-x · Cited by 75 · see citing works
Out, D., Pieper, S., Bakermans‐Kranenburg, M. J., Zeskind, P. S., & van IJzendoorn, M. H. (2010) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2010.05.003 · Cited by 65 · see citing works
Maternal stress and depression and the lateralisation of infant cradling
Reissland, N., Hopkins, B., Helms, P. J. B., & Williams, B. (2007) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2007.01791.x · Cited by 65 · see citing works
Liedman, R., Hansson, S. R., Howe, D., Igidbashian, S., McLeod, A., Russell, R. J., & Åkerlund, M. (2008) · Gynecological Endocrinology · doi:10.1080/09513590802306218 · Cited by 60 · see citing works
Crying as a Sign, a Symptom and a Signal
Mundy, P. (2002) · Journal of Applied Research in Intellectual Disabilities · doi:10.1046/j.1468-3148.2002.00088.x · Cited by 54 · see citing works
Plasma levels of oxytocin during the menstrual cycle, pregnancy and following treatment with HMG
Stock, S., Bremme, K., & UVNÄS‐MOBERG, K. (1991) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a137484 · Cited by 45 · see citing works
A reassessment of the role of pitch and duration in adults' responses to infant crying
Dessureau, B., Kurowski, C. O., & Thompson, N. S. (1998) · Infant Behavior and Development · doi:10.1016/s0163-6383(98)90013-3 · Cited by 42 · see citing works
Pitch of infant crying and caregiver responses in a natural setting
Zeskind, P. S., & Collins, V. C. (1987) · Infant Behavior and Development · doi:10.1016/0163-6383(87)90046-4 · Cited by 38 · see citing works
It's not what you say but how you say it
(2007) · BMJ · doi:10.1136/bmj.334.7608.1344 · Cited by 37 · see citing works
Influences of disgust sensitivity on hemodynamic responses towards a disgust-inducing film clip
Stark, R. M., Schienle, A., Sarlo, M., Palomba, D., Walter, B., & Vaitl, D. (2005) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2005.01.010 · Cited by 36 · see citing works
The Perceptions of Infant Distress Signals Varying in Pitch by Cocaine‐Using Mothers
Schuetze, P. A., Zeskind, P. S., & Eiden, R. D. (2003) · Infancy · doi:10.1207/s15327078in0401_4 · Cited by 32 · see citing works
Why are infants held on the left? A test of the attention hypothesis with a doll, a book, and a bag
Harris, L. J., Cárdenas, R. A., Spradlin, M. P., & Almerigi, J. B. (2009) · Laterality Asymmetries of Body Brain and Cognition · doi:10.1080/13576500903064018 · Cited by 22 · see citing works
Crying as a Sign, a Symptom, and a Signal
Goldson, E. (2001) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200102000-00010 · Cited by 19 · see citing works
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The brain basis of emotion: a meta-analytic review
Lindquist, K. A., Wager, T. D., Kober, H., Bliss-Moreau, E., & Barrett, L. F. (2012) · Behavioral and Brain Sciences · doi:10.1017/s0140525x11000446 · Cited by 2,320 · see citing works
“First, in a randomized control trial (Riem et al. 2011), experimentally elevated oxytocin versus placebo resulted in increased responses to the cries of unrelated babies, in the inferior frontal gyrus and insula, and decreased responses in the right amygdala.”
Millan, M. J., Agid, Y., Brüne, M., Bullmore, E. T., Carter, C. S., Clayton, N. S., Connor, R., Davis, S., Deakin, B., DeRubeis, R. J., et al. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3628 · Cited by 1,292 · see citing works
Bernhardt, B. C., & Singer, T. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150536 · Cited by 952 · see citing works
Oxytocin and social affiliation in humans
Feldman, R. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.01.008 · Cited by 767 · see citing works
Emotion regulation in parenthood
Rutherford, H. J. V., Wallace, N. S., Laurent, H. K., & Mayes, L. C. (2015) · Developmental Review · doi:10.1016/j.dr.2014.12.008 · Cited by 485 · see citing works
“This hormonal change may help sensitize new parents to infant emotion cues; indeed, oxytocin appears to enhance neural responding to infant stimuli among both parents and non-parents (Atzil, Hendler, & Feldman, 2011; Atzil, Hendler, Zagoory-Sharon, Winetraub, & Feldman, 2012; Riem et al., 2011), with oxytocin-related…”
BackgroundDe Dreu, C. K. W. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.009 · Cited by 455 · see citing works
The biology of mammalian parenting and its effect on offspring social development
Rilling, J. K., & Young, L. J. (2014) · Science · doi:10.1126/science.1252723 · Cited by 452 · see citing works
The adaptive human parental brain: implications for children's social development
Feldman, R. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.04.004 · Cited by 419 · see citing works
Autism, oxytocin and interoception
Quattrocki, E., & Friston, K. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.09.012 · Cited by 393 · see citing works
Sensitive Parenting Is Associated with Plasma Oxytocin and Polymorphisms in the OXTR and CD38 Genes
Feldman, R., Zagoory-Sharon, O., Weisman, O., Schneiderman, I., Gordon, I., Maoz, R., Shalev, I., & Ebstein, R. P. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.12.025 · Cited by 393 · see citing works
Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.34 · Cited by 383 · see citing works
Oxytocin, motivation and the role of dopamine
Love, T. M. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.06.011 · Cited by 369 · see citing works
Van IJzendoorn, M. H., & Bakermans-Kranenburg, M. J. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.07.008 · Cited by 365 · see citing works
Neuroendocrine regulation of maternal behavior
Bridges, R. S. (2015) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.11.007 · Cited by 346 · see citing works
van Anders, S. M., Goldey, K. L., & Kuo, P. X. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.06.001 · Cited by 321 · see citing works
Swain, J. E., Kim, P., Spicer, J., Ho, S. S., Dayton, C. J., Elmadih, A., & Abel, K. M. (2014) · Brain Research · doi:10.1016/j.brainres.2014.03.007 · Cited by 290 · see citing works
Bethlehem, R. A. I., van Honk, J., Auyeung, B., & Baron-Cohen, S. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.10.011 · Cited by 285 · see citing works
The contributions of oxytocin and vasopressin pathway genes to human behavior
Ebstein, R. P., Knafo, A., Mankuta, D., Chew, S. H., & Lai, P. S. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.014 · Cited by 283 · see citing works
Immunohistochemical localization of oxytocin receptors in human brain
Boccia, M. L., Petrusz, P., Suzuki, K., Marson, L., & Pedersen, C. A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.08.048 · Cited by 276 · see citing works
The maternal brain and its plasticity in humans
Kim, P., Strathearn, L., & Swain, J. E. (2016) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.08.001 · Cited by 278 · see citing works
The animal and human neuroendocrinology of social cognition, motivation and behavior
McCall, C., & Singer, T. (2012) · Nature Neuroscience · doi:10.1038/nn.3084 · Cited by 273 · see citing works
Oxytocin, stress and social behavior: neurogenetics of the human oxytocin system
Kumsta, R., & Heinrichs, M. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.09.004 · Cited by 265 · see citing works
Oxytocin facilitates protective responses to aversive social stimuli in males
Striepens, N., Scheele, D., Kendrick, K. M., Becker, B., Schäfer, L., Schwalba, K., Reul, J., Maier, W., & Hurlemann, R. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208852109 · Cited by 242 · see citing works
Auyeung, B., Lombardo, M. V., Heinrichs, M., Chakrabarti, B., Sule, A., Deakin, J. B., Bethlehem, R. A. I., Dickens, L., Mooney, N., Sipple, J. A. N., et al. (2015) · Translational Psychiatry · doi:10.1038/tp.2014.146 · Cited by 234 · see citing works
The neural and hormonal bases of human parentalcare
Rilling, J. K. (2013) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.12.017 · Cited by 230 · see citing works
Chen, F. S., Kumsta, R., von Dawans, B., Monakhov, M., Ebstein, R. P., & Heinrichs, M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113079108 · Cited by 268 · see citing works
Tone, E. B., & Tully, E. C. (2014) · Development and Psychopathology · doi:10.1017/s0954579414001199 · Cited by 231 · see citing works
Baribeau, D. A., & Anagnostou, E. A. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00335 · Cited by 229 · see citing works
Puglia, M. H., Lillard, T. S., Morris, J. P., & Connelly, J. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1422096112 · Cited by 216 · see citing works
Prenatal and postnatal hormone effects on the human brain and cognition
Bonnie Auyeung, B., Lombardo, M. V., & Baron‐Cohen, S. (2013) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1268-2 · Cited by 219 · see citing works
Treatment of Posttraumatic Stress Disorder: A State-of-the-art Review
Burback, L., Brémault‐Phillips, S., Nijdam, M. J., McFARLANE, A. C., & Vermetten, E. H. G. J. M. (2023) · Current Neuropharmacology · doi:10.2174/1570159x21666230428091433 · Cited by 232 · see citing works
Oxytocin and social motivation
Gordon, I., Martin, C., Feldman, R., & Leckman, J. F. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.07.007 · Cited by 211 · see citing works
Paloyelis, Y., Doyle, O. M., Zelaya, F. O., Maltezos, S., Williams, S. C., Fotopoulou, A., & Howard, M. A. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.10.005 · Cited by 187 · see citing works
Oxytocin and early parent-infant interactions: A systematic review
Scatliffe, N., Casavant, S. G., Vittner, D. J., & Cong, X. S. (2019) · International Journal of Nursing Sciences · doi:10.1016/j.ijnss.2019.09.009 · Cited by 202 · see citing works
Oxytocin and mutual communication in mother-infant bonding
Nagasawa, M., Okabe, S., Mogi, K., & Kikusui, T. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00031 · Cited by 202 · see citing works
Social “wanting” dysfunction in autism: neurobiological underpinnings and treatment implications
Kohls, G., Chevallier, C., Troiani, V., & Schultz, R. T. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-10 · Cited by 197 · see citing works
Oxytocin increases amygdala reactivity to threatening scenes in females
Lischke, A., Gamer, M., Berger, C., Grossmann, A., Hauenstein, K., Heinrichs, M., Herpertz, S. C., & Domes, G. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.01.011 · Cited by 194 · see citing works
Riem, M. M. E., van IJzendoorn, M. H., Tops, M., Boksem, M. A. S., Rombouts, S. A. R. B., & Bakermans-Kranenburg, M. J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.313 · Cited by 191 · see citing works
Walker, S. C., Trotter, P. D., Swaney, W. T., Marshall, A. G., & McGlone, F. P. (2017) · Neuropeptides · doi:10.1016/j.npep.2017.01.001 · Cited by 193 · see citing works
Oxytocin improves behavioural and neural deficits in inferring others’ social emotions in autism
Aoki, Y., Yahata, N., Watanabe, T., Takano, Y., Kawakubo, Y., Kuwabara, H., Iwashiro, N., Natsubori, T., Inoue, H., Suga, M., et al. (2014) · Brain · doi:10.1093/brain/awu231 · Cited by 187 · see citing works
Stratified medicine for mental disorders
Schumann, G., Binder, E. B., Holte, A., de Kloet, E. R., Oedegaard, K. J., Robbins, T. W., Walker-Tilley, T. R., Bitter, I., Brown, V. J., Buitelaar, J., et al. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.09.010 · Cited by 186 · see citing works
Brown, S. L., & Brown, R. M. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.004 · Cited by 190 · see citing works
Switching brain serotonin with oxytocin
Mottolese, R., Redouté, J., Costes, N., Le Bars, D., & Sirigu, A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1319810111 · Cited by 179 · see citing works
MacDonald, K., & Feifel, D. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00035 · Cited by 181 · see citing works
Wigton, R., Radua, J., Allen, P., Averbeck, B., Meyer-Lindenberg, A., McGuire, P., Shergill, S. S., & Fusar-Poli, P. (2015) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.130289 · Cited by 179 · see citing works
Human neuroimaging of oxytocin and vasopressin in social cognition
Zink, C. F., & Meyer-Lindenberg, A. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.01.016 · Cited by 176 · see citing works
Intranasal administration of oxytocin: behavioral and clinical effects, a review
Veening, J. G., & Olivier, B. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.04.012 · Cited by 169 · see citing works
Neurobiology of culturally common maternal responses to infant cry
Bornstein, M. H., Putnick, D. L., Rigo, P., Esposito, G., Swain, J. E., Suwalsky, J. T. D., Su, X., Du, X., Zhang, K., Cote, L. R., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1712022114 · Cited by 168 · see citing works
Marsh, A. A. (2018) · Annual Review of Psychology · doi:10.1146/annurev-psych-010418-103010 · Cited by 164 · see citing works
The Resilience handbook: approaches to stress and trauma
(2014) · Choice Reviews Online · doi:10.5860/choice.51-5313 · Cited by 161 · see citing works
Neural mechanisms of social decision-making in the primate amygdala
Chang, S. W. C., Fagan, N. A., Toda, K., Utevsky, A. V., Pearson, J. M., & Platt, M. L. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1514761112 · Cited by 157 · see citing works
Lonstein, J. S., Lévy, F., & Fleming, A. S. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.06.011 · Cited by 151 · see citing works
Yamasue, H., Yee, J. R., Hurlemann, R., Rilling, J. K., Chen, F. S., Meyer-Lindenberg, A., & Tost, H. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3327-12.2012 · Cited by 149 · see citing works
Feldman, R., & Bakermans-Kranenburg, M. J. (2017) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2017.02.011 · Cited by 160 · see citing works
Oxytocin׳s role in anxiety: A critical appraisal
MacDonald, K., & Feifel, D. (2014) · Brain Research · doi:10.1016/j.brainres.2014.01.025 · Cited by 139 · see citing works
Gur, R., Tendler, A., & Wagner, S. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.03.022 · Cited by 144 · see citing works
Elevated salivary levels of oxytocin persist more than 7 h after intranasal administration
van IJzendoorn, M. H., Bhandari, R., van der Veen, R., Grewen, K. M., & Bakermans-Kranenburg, M. J. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00174 · Cited by 137 · see citing works
Self-citationRiem, M. M. E., Alink, L. R. A., Out, D., van IJzendoorn, M. H., & Bakermans‐Kranenburg, M. J. (2015) · Development and Psychopathology · doi:10.1017/s0954579415000127 · Cited by 140 · see citing works
Oxytocin and the Neurobiology of Prosocial Behavior
Marsh, N., Marsh, A. A., Lee, M. R., & Hurlemann, R. (2020) · The Neuroscientist · doi:10.1177/1073858420960111 · Cited by 149 · see citing works
MacDonald, K., MacDonald, T. M., Brüne, M., Lamb, K., Wilson, M. P., Golshan, S., & Feifel, D. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.05.014 · Cited by 140 · see citing works
Dissecting the Role of Oxytocin in the Formation and Loss of Social Relationships
Hurlemann, R., & Scheele, D. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.05.013 · Cited by 136 · see citing works
The neurobiology of fatherhood
Rilling, J. K., & Mascaro, J. S. (2017) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2017.02.013 · Cited by 135 · see citing works
Riem, M. M. E., Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., Out, D., & Rombouts, S. A. R. B. (2012) · Attachment & Human Development · doi:10.1080/14616734.2012.727252 · Cited by 134 · see citing works
The Insula: A Brain Stimulation Target for the Treatment of Addiction
Ibrahim, C., Rubin-Kahana, D. S., Pushparaj, A., Musiol, M., Blumberger, D. M., Daskalakis, Z. J., Zangen, A., & Le Foll, B. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00720 · Cited by 133 · see citing works
Ma, Y., Shamay-Tsoory, S., Han, S., & Zink, C. F. (2016) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2015.10.009 · Cited by 131 · see citing works
Bakermans‐Kranenburg, M. J., van IJzendoorn, M. H., Riem, M. M. E., Mattie Tops, A., & Alink, L. R. A. (2011) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsr067 · Cited by 126 · see citing works
Koch, S. B. J., van Zuiden, M., Nawijn, L., Frijling, J. L., Veltman, D. J., & Olff, M. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.11.018 · Cited by 123 · see citing works
Grace, S. A., Rossell, S. L., Heinrichs, M., Kordsachia, C., & Labuschagne, I. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.05.031 · Cited by 120 · see citing works
Oxytocin and the social brain: Neural mechanisms and perspectives in human research
Kanat, M., Heinrichs, M., & Domes, G. (2014) · Brain Research · doi:10.1016/j.brainres.2013.11.003 · Cited by 122 · see citing works
Montag, C., Brockmann, E.-M., Lehmann, A. I., Müller, D. J., Rujescu, D., & Gallinat, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051882 · Cited by 123 · see citing works
Lawson, E. A., Holsen, L. M., Santin, M., Meenaghan, E. M., Eddy, K. T., Becker, A. E., Herzog, D. B., Goldstein, J. M., & Klibanski, A. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1702 · Cited by 121 · see citing works
Oxytocin in the socioemotional brain: implications for psychiatric disorders
Kirsch, P. (2015) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2015.17.4/pkirsch · Cited by 122 · see citing works
The neurobiological causes and effects of alloparenting
Kenkel, W. M., Perkeybile, A. M., & Carter, C. S. (2016) · Developmental Neurobiology · doi:10.1002/dneu.22465 · Cited by 120 · see citing works
Overview of human oxytocin research
Kendrick, K. M., Guastella, A. J., & Becker, B. (2017) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2017_19 · Cited by 121 · see citing works
Oxytocin and postpartum depression: Delivering on what's known and what's not
Kim, S., Soeken, T. A., CROMER, S. J., Martinez, S. R., Hardy, L. R., & Strathearn, L. (2013) · Brain Research · doi:10.1016/j.brainres.2013.11.009 · Cited by 116 · see citing works
Parenting and Beyond: Common Neurocircuits Underlying Parental and Altruistic Caregiving
Swain, J. E., Konrath, S., Brown, S. L., Finegood, E. D., Akce, L., Dayton, C. J., & Ho, S.-H. S. (2012) · Parenting · doi:10.1080/15295192.2012.680409 · Cited by 117 · see citing works
Hormonal contraceptives suppress oxytocin-induced brain reward responses to the partner’s face
Scheele, D., Plota, J., Stoffel-Wagner, B., Maier, W., & Hurlemann, R. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsv157 · Cited by 116 · see citing works
“For example, OXT altered neural responses to infant crying (Riem et al., 2011) and facilitated spontaneous anthropomorphism (Scheele et al.”
BackgroundNeural, cognitive, and evolutionary foundations of human altruism
Marsh, A. A. (2015) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1377 · Cited by 119 · see citing works
De Dreu, C. K. W. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.10.003 · Cited by 114 · see citing works
Riem, M. M. E., Bakermans‐Kranenburg, M. J., Huffmeijer, R., & van IJzendoorn, M. H. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.12.023 · Cited by 114 · see citing works
Oxytocin and Autism: A Systematic Review of Randomized Controlled Trials
Preti, A., Melis, M., Siddi, S., Vellante, M., Doneddu, G., & Fadda, R. (2014) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2013.0040 · Cited by 114 · see citing works
Neural signatures of betrayal aversion: an fMRI study of trust
Aimone, J. A., Houser, D. E., & Weber, B. (2014) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2013.2127 · Cited by 113 · see citing works
Oxytocin pathways in the intergenerational transmission of maternal early life stress
Töpfer, P., Heim, C. C., Entringer, S., Binder, E. B., Wadhwa, P. D., & Buß, C. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.12.026 · Cited by 114 · see citing works
Oxytocin in schizophrenia: a review of evidence for its therapeutic effects
MacDonald, K. S., & Feifel, D. (2011) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2011.00634.x · Cited by 111 · see citing works
Neuroendocrinology of Parental Response to Baby‐Cry
Swain, J. E., Kim, P., & Ho, S. S. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02212.x · Cited by 106 · see citing works
Intranasal oxytocin, but not vasopressin, augments neural responses to toddlers in human fathers
Li, T., Chen, X., Mascaro, J., Haroon, E., & Rilling, J. K. (2017) · Hormones and Behavior · doi:10.1016/j.yhbeh.2017.01.006 · Cited by 105 · see citing works
Applying socioendocrinology to evolutionary models: Fatherhood and physiology
Gettler, L. T. (2014) · Evolutionary Anthropology Issues News and Reviews · doi:10.1002/evan.21412 · Cited by 99 · see citing works
Towards a neural model of infant cry perception
Witteman, J., Van IJzendoorn, M. H., Rilling, J. K., Bos, P. A., Schiller, N. O., & Bakermans-Kranenburg, M. J. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.01.026 · Cited by 94 · see citing works
Relationships Between Academic Motivation, Self-Efficacy, and Academic Procrastination
Cerino, E. S. (2014) · Psi Chi Journal of Psychological Research · doi:10.24839/2164-8204.jn19.4.156 · Cited by 110 · see citing works
Insular function in autism: Update and future directions in neuroimaging and interventions
Nomi, J. S., Molnar-Szakacs, I., & Uddin, L. Q. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.10.015 · Cited by 95 · see citing works
Wang, D., Yan, X., Li, M., & Ma, Y. (2017) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsx085 · Cited by 86 · see citing works
Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal
Riem, M. M. E., van IJzendoorn, M. H., Tops, M., Boksem, M. A. S., Rombouts, S. A. R. B., & Bakermans-Kranenburg, M. J. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.01.011 · Cited by 91 · see citing works
Antiaggressive activity of central oxytocin in male rats
Calcagnoli, F., de Boer, S. F., Althaus, M., den Boer, J. A., & Koolhaas, J. M. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3124-7 · Cited by 90 · see citing works
Oxytocin and the modulation of pain experience: Implications for chronic pain management
Tracy, L. M., Georgiou‐Karistianis, N., Gibson, S. J., & Giummarra, M. J. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.013 · Cited by 89 · see citing works
Behavioral and genetic correlates of the neural response to infant crying among human fathers
Mascaro, J. S., Hackett, P. D., Gouzoules, H., Lori, A., & Rilling, J. K. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nst166 · Cited by 89 · see citing works
Deer Mothers Are Sensitive to Infant Distress Vocalizations of Diverse Mammalian Species
Lingle, S., & Riede, T. (2014) · The American Naturalist · doi:10.1086/677677 · Cited by 87 · see citing works
Marsh, A. A., Yu, H. H., Pine, D. S., Gorodetsky, E. K., Goldman, D., & Blair, R. J. R. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2775-0 · Cited by 87 · see citing works
Oxytocin Modulates Attention Switching Between Interoceptive Signals and External Social Cues
Yao, S., Becker, B., Zhao, W., Zhao, Z., Kou, J., Ma, X., Geng, Y., Ren, P., & Kendrick, K. M. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.189 · Cited by 86 · see citing works
Rocchetti, M., Radua, J., Paloyelis, Y., Xenaki, L., Frascarelli, M., Caverzasi, E., Politi, P., & Fusar‐Poli, P. (2014) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12185 · Cited by 83 · see citing works
Synchronous caregiving from birth to adulthood tunes humans’ social brain
Ulmer-Yaniv, A., Salomon, R., Waidergoren, S., Shimon-Raz, O., Djalovski, A., & Feldman, R. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2012900118 · Cited by 81 · see citing works
- Authors
- Riem, M. M. E., Bakermans-Kranenburg, M. J., Pieper, S., Tops, M., Boksem, M. A. S., Vermeiren, R. R. J. M., van IJzendoorn, M. H., & Rombouts, S. A. R. B.
- Affiliations
- Leiden University (NL)
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 70
- Issue
- 3
- Pages
- 291-297
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2163954344
- Cited by
- 366
- References
- 90
- Citations by year
- 2026: 10 · 2025: 4 · 2024: 8 · 2023: 11 · 2022: 16 · 2021: 15 · 2020: 33 · 2019: 27 · 2018: 24 · 2017: 33 · 2016: 34 · 2015: 30 · 2014: 39 · 2013: 39 · 2012: 28
- FWCI
- 52.06
- Type
- journal article
- Language
- en
- Open access
- green
- pure.eur.nl
- Licence
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion, other-oa)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- VU Research Portal (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Health Sciences › Health Professions › Pharmacy › Infant Health and Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Keywords
- oxytocin, infant crying, amygdala, insula, inferior frontal gyrus, maternal responsiveness, mother-infant bonding, parental care, empathy, anxiety, aversion
- MeSH terms
- Adult, Amygdala, Auditory Perception, Cerebral Cortex, Crying, Empathy, Female, Frontal Lobe, Humans, Middle Aged, Neurons, Oxytocin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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