The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Common questions and misconceptions about protein supplementation: what does the scientific evidence really show?
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In the citing paper
“However, within the sports nutrition literature, athletes are generally advised to consume between 1.4–2.0 g/kg/day to support muscle maintenance, recovery, and adaptation to training [18,19].”
From Optimizing Performance Nutrition for Adolescent Athletes: A Review of Dietary Needs, Risks, and Practical Strategies (2025) · cites this paper as [18]
In the citing paper
“Studies recommend consuming 20–40 g of high-quality protein per meal, spaced every 3–4 h throughout the day [18,19]. This approach supports sustained anabolic signaling and muscle recovery, especially during the 16–48 h window following resistance exercise.”
From Optimizing Performance Nutrition for Adolescent Athletes: A Review of Dietary Needs, Risks, and Practical Strategies (2025) · cites this paper as [18]
In the citing paper
“Beyond total intake, the timing and distribution of protein are critical for maximizing MPS.”
From Optimizing Performance Nutrition for Adolescent Athletes: A Review of Dietary Needs, Risks, and Practical Strategies (2025) · cites this paper as [18]
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Citations
Cites
Slow and fast dietary proteins differently modulate postprandial protein accretion
Boirie, Y., Dangin, M., Gachon, P., Vasson, M.-P., Maubois, J.-L., & Beaufrère, B. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14930 · Cited by 1,453
Thomas, D. T., Erdman, K. A., & Burke, L. M. (2016) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2015.12.006 · Cited by 1,359 · cited 3×
“Operational definitions include protein intakes ranging from 1.0–1.8 g/kg/day, which is greater than the RDA of 0.8 g/kg/day but on the low end of recommendations for active individuals [21,22].”
BackgroundInfluentialMorton, R. W., Murphy, K. T., McKellar, S. R., Schoenfeld, B. J., Henselmans, M., Helms, E., Aragon, A. A., Devries, M. C., Banfield, L., Krieger, J. W., et al. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-097608 · Cited by 1,269 · cited 1×
“As such, athletes are often recommended to ingest a higher protein intake much greater than the general population (e.g. 1.6 g/kg/day vs. 0.8 g/kg/day [2,71].”
BackgroundInfluentialSiri-Tarino, P. W., Sun, Q., Hu, F. B., & Krauss, R. M. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27725 · Cited by 1,253
Micha, R., Wallace, S. K., & Mozaffarian, D. (2010) · Circulation · doi:10.1161/circulationaha.109.924977 · Cited by 1,244
Tang, J. E., Moore, D. R., Kujbida, G. W., Tarnopolsky, M. A., & Phillips, S. M. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00076.2009 · Cited by 998
Moore, D. R., Robinson, M. J., Fry, J. L., Tang, J. E., Glover, E. I., Wilkinson, S. B., Prior, T., Tarnopolsky, M. A., & Phillips, S. M. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26401 · Cited by 973
Red and Processed Meat and Colorectal Cancer Incidence: Meta-Analysis of Prospective Studies
Chan, D. S. M., Lau, R., Aune, D., Vieira, R., Greenwood, D. C., Kampman, E., & Norat, T. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020456 · Cited by 903
International Society of Sports Nutrition Position Stand: protein and exercise
Jäger, R., Kerksick, C. M., Campbell, B. I., Cribb, P. J., Wells, S. D., Skwiat, T. M., Purpura, M., Ziegenfuss, T. N., Ferrando, A. A., Arent, S. M., et al. (2017) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-017-0177-8 · Cited by 873
Self-citationCermak, N. M., Res, P. T., de Groot, L. C., Saris, W. H., & van Loon, L. J. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.037556 · Cited by 827
Research works printed but not linked: 146
- 10.1186/1550-2783-4-8 · DOI · Paper page
- 10.3390/nu12061890 · DOI
- 10.3389/fnut.2018.00083 · DOI · Paper page
- 10.1080/15438627.2018.1523167 · DOI · Paper page
- 10.1186/s12970-018-0215-1 · DOI · Paper page
- 10.1113/jphysiol.2012.244897 · DOI · Paper page
- 10.1053/j.ajkd.2006.08.023 · DOI · Paper page
- 10.1002/jcsm.12264 · DOI
- 10.2183/pjab.93.001 · DOI
- 10.1186/s12944-018-0791-8 · DOI
- 10.1186/1743-7075-2-25 · DOI · Paper page
- Brandle E, Sieberth HG, Hautmann RE. Effect of chronic dietary protein intake on the renal function in healthy subjects. Eur J Clin Nutr. 1996;50:734–740.
- 10.1056/NEJM198209093071104 · DOI · Paper page
- 10.1093/jn/130.4.886 · DOI
- 10.1146/annurev-nutr-071714-034426 · DOI
- 10.1186/s12970-017-0177-8 · DOI · Paper page
- 10.1123/ijsnem.10.1.28 · DOI · Paper page
- 10.1519/00124278-200608000-00028 · DOI · Paper page
- 10.1186/1743-7075-5-11 · DOI · Paper page
- 10.1155/2016/9104792 · DOI · Paper page
- 10.3810/psm.2011.05.1893 · DOI
- Antonio J, Ellerbroek A. Case reports on well-trained bodybuilders: two years on a high protein diet. J Exerc Physiol Online. 2018;21.
- 10.1210/jc.2011-2165 · DOI
- 10.1080/07315724.2004.10719435 · DOI · Paper page
- 10.1093/jn/133.2.411 · DOI · Paper page
- 10.1093/ajcn/81.6.1298 · DOI · Paper page
- 10.1038/sj.ijo.0801048 · DOI
- 10.2337/diacare.25.3.425 · DOI · Paper page
- 10.7326/0003-4819-142-6-200503150-00006 · DOI · Paper page
- 10.3390/nu10010054 · DOI
- FAO/WHO/UNU. Protein and amino acid requirements in human nutrition. Geneva, Switzerland: World Health Organization; 2002.
- 10.1016/j.clnu.2015.03.016 · DOI
- 10.1038/ijo.2010.254 · DOI
- 10.1002/oby.20812 · DOI
- 10.1002/oby.23428 · DOI
- Rozenek R, Ward P, Long S, et al. Effects of high-calorie supplements on body composition and muscular strength following resistance training. J Sports Med Phys Fitness. 2002;42:340–347.
- 10.3389/fspor.2021.683327 · DOI
- Antonio J, Ellerbroek A. Case reports on well-trained bodybuilders: Two years on a high protein diet. J Exerc Physiol Online. 2018;21:14–24.
- 10.3390/jfmk3040062 · DOI
- 10.1186/s12970-018-0210-6 · DOI · Paper page
- 10.1186/s12970-015-0100-0 · DOI · Paper page
- 10.1186/s12970-016-0114-2 · DOI · Paper page
- Spillane M, Willoughby DS. Daily overfeeding from protein and/or carbohydrate supplementation for eight weeks in conjunction with resistance training does not improve body composition and muscle strength or increase markers indicative of muscle protein synthesis and myogenesis in resistance-trained males. J Sports Sci Med. 2016;15:17–25.
- 10.2337/dc14-0761 · DOI
- 10.1186/1743-7075-7-68 · DOI
- Leaf A, Antonio J. The effects of overfeeding on body composition: the role of macronutrient composition - a narrative review. Int J Exerc Sci. 2017;10(8):1275–1296. · DOI
- 10.1136/bjsports-2017-097608 · DOI · Paper page
- 10.1056/NEJM199406233302510 · DOI
- 10.1093/jn/128.6.1051 · DOI · Paper page
- 10.1359/jbmr.090515 · DOI
- 10.1093/ajcn/88.4.1159 · DOI
- 10.1007/s40279-019-01161-2 · DOI · Paper page
- 10.1210/jc.2004-0179 · DOI · Paper page
- 10.1093/ajcn/83.6.1254 · DOI
- 10.1093/ajcn/85.1.300S · DOI
- 10.1249/MSS.0b013e3181a8c717 · DOI
- 10.1007/s00198-023-06840-5 · DOI
- 10.1186/s12970-018-0210-6 · DOI · Paper page
- 10.3390/jfmk3040062 · DOI
- 10.1007/s00726-018-2640-5 · DOI · Paper page
- 10.3945/jn.114.204305 · DOI · Paper page
- 10.3390/nu15010035 · DOI
- 10.3390/nu14183688 · DOI
- 10.1093/jn/nxac222 · DOI · Paper page
- 10.1007/s00726-018-2640-5 · DOI · Paper page
- 10.1093/jn/133.5.1308 · DOI · Paper page
- 10.1093/ajcn/86.2.373 · DOI · Paper page
- 10.1093/jn/131.10.3228S · DOI · Paper page
- 10.3945/ajcn.110.008102 · DOI · Paper page
- 10.1152/ajpendo.00106.2012 · DOI
- 10.1017/S0007114511002182 · DOI
- 10.3390/nu13061962 · DOI
- 10.3390/nu13124234 · DOI
- 10.1017/S0007114521000635 · DOI · Paper page
- 10.1016/j.exger.2005.10.006 · DOI · Paper page
- 10.1139/apnm-2015-0550 · DOI · Paper page
- 10.3390/nu14010029 · DOI · Paper page
- 10.3390/nu15071746 · DOI
- 10.1186/s12970-017-0192-9 · DOI
- 10.1186/1475-2891-3-22 · DOI
- 10.1186/1550-2783-6-8 · DOI · Paper page
- 10.1186/s12970-020-00397-y · DOI
- 10.1186/s12970-020-00394-1 · DOI
- 10.1007/s40279-021-01434-9 · DOI · Paper page
- 10.3390/nu10121841 · DOI · Paper page
- 10.1093/nutrit/nuaa117 · DOI
- Chicken, broiler or fryers, breast, skinless, boneless, meat only, cooked, braised. Nutrition Facts Search Tool. Food Data Central: USDA; 2019.
- Antonio J, Axelrod C, Ellerbroek A, et al. Effects of 5-day heat acclimation on workers wearing personal protective clothing. J Exerc Nutr. 2018;1(1):1.
- 10.1093/nutrit/nux025 · DOI
- 10.1016/j.nutos.2021.02.006 · DOI
- 10.1016/j.meatsci.2015.05.012 · DOI · Paper page
- 10.1079/BJN20051427 · DOI
- 10.1080/10406638.2018.1559208 · DOI
- 10.1080/10590501.2011.629974 · DOI · Paper page
- 10.1093/toxsci/kfv040 · DOI · Paper page
- 10.3748/wjg.v19.i7.1020 · DOI
- 10.1016/j.critrevonc.2015.11.008 · DOI
- 10.1093/jnci/djj301 · DOI
- 10.1002/ijc.10126 · DOI · Paper page
- 10.1007/s10654-021-00741-9 · DOI · Paper page
- 10.7326/M19-0699 · DOI
- 10.1111/1541-4337.12501 · DOI
- 10.3389/fnut.2023.1078963 · DOI
- 10.3389/fnut.2022.942155 · DOI
- Sandhu MS, White IR, K M. Systematic review of the prospective cohort studies on meat consumption and colorectal cancer risk: a meta-analytical approach. Cancer Epidemiol Biomarkers Prev. 2001;10:439–446.
- 10.3390/nu14245213 · DOI
- 10.3390/nu11040826 · DOI
- 10.1111/nure.12028 · DOI
- 10.1016/j.amjmed.2012.01.022 · DOI
- 10.1007/s10654-021-00762-4 · DOI
- 10.1093/ajcn/nqaa448 · DOI
- 10.1201/b11928 · DOI
- 10.1016/S0002-8223(02)90346-9 · DOI · Paper page
- 10.1093/ajcn/77.1.109 · DOI · Paper page
- 10.1097/MCO.0b013e328332f9b7 · DOI
- 10.1093/ajcn/86.4.995 · DOI · Paper page
- 10.3390/nu15040838 · DOI
- 10.1093/jn/nxac150 · DOI
- 10.7554/eLife.76854 · DOI
- 10.1093/nutrit/nuaa104 · DOI · Paper page
- 10.3945/ajcn.114.084061 · DOI · Paper page
- 10.1093/ajcn/87.1.150 · DOI · Paper page
- 10.1007/s12603-012-0064-6 · DOI
- 10.1093/advances/nmy003 · DOI
- 10.1111/j.1469-7793.2001.00301.x · DOI · Paper page
- 10.1152/jappl.2000.88.2.386 · DOI · Paper page
- 10.1152/ajpendo.00325.2016 · DOI · Paper page
- 10.1152/ajpendo.00166.2006 · DOI · Paper page
- 10.3389/fnut.2018.00083 · DOI · Paper page
- 10.1007/s007260170063 · DOI
- 10.1519/JSC.0b013e3181ddfacf · DOI
- 10.1055/s-2007-971977 · DOI
- 10.7150/ijms.19584 · DOI · Paper page
- 10.3390/nu10040494 · DOI
- 10.1152/japplphysiol.00008.2007 · DOI · Paper page
- 10.1249/MSS.0b013e318257d2db · DOI
- 10.1016/j.bbi.2013.10.002 · DOI · Paper page
- 10.1152/physiolgenomics.00073.2011 · DOI
- 10.1186/1550-2783-11-20 · DOI · Paper page
- 10.1096/fj.13-230227 · DOI · Paper page
- 10.1080/15502783.2023.2263409 · DOI
- 10.1016/S0955-2863(98)00087-4 · DOI · Paper page
- 10.1152/ajpendo.00334.2003 · DOI · Paper page
- 10.1152/ajpendo.1997.273.1.E122 · DOI · Paper page
- 10.1186/s12970-020-00401-5 · DOI
- 10.1016/j.clnu.2020.07.019 · DOI
Cited by
Everett, S. (2025) · Nutrients · doi:10.3390/nu17172792 · Cited by 37
The harms of high protein intake: conjectured, postulated, claimed, and presumed, but shown?
French, S. J., Kanter, M., Maki, K. C., Rust, B. M., & Allison, D. B. (2025) · The American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2025.05.002 · Cited by 15
Metadata
- Authors
- Antonio, J., Evans, C., Ferrando, A. A., Stout, J. R., Antonio, B., Cintineo, H. P., Harty, P., Arent, S. M., Candow, D. G., Forbes, S. C., Kerksick, C. M., Pereira, F., Gonzalez, D., & Kreider, R. B.
- Affiliations
- Nova Southeastern University, Department of Health and Human Performance, Davie, FL, USA
- University of Arkansas for Medical Sciences, Department of Geriatrics, Little Rock, AR, USA
- University of Central Florida, School of Kinesiology and Rehabilitation Science, Orlando, FL, USA
- Lindenwood University, Exercise and Performance Nutrition Laboratory, St. Charles, MO, USA
- University of South Carolina, Department of Exercise Science, Arnold School of Public Health, Columbia, SC, USA
- University of Regina, Faculty of Kinesiology and Health Studies, Regina, Canada
- Brandon University, Department of Physical Education, Faculty of Education, Brandon, MB, Canada
- Keiser University, Exercise and Sport Science, West Palm Beach Flagship Campus, West Palm Beach, FL, USA
- Texas A&M University, Exercise & Sport Nutrition Lab, Human Clinical Research Facility, Department of Health & Kinesiology, College Station, TX, USA
- ORCID
- Venue
- Journal of the International Society of Sports Nutrition
- Publisher
- Informa UK Limited
- Published
- 2024-04-16
- Volume
- 21
- Issue
- 1
- ISSN
- 1550-2783
- Cited by
- 27
- References
- 64
- Language
- en
- Funders
- no funding
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