Cited by 235Neural and Behavioral Psychology StudiesPsychopathy, Forensic Psychiatry, Sexual OffendingBullying, Victimization, and Aggression

The Neurobiology of Impulsive Aggression

Open access
Blair, Robert J. R.·2016·Journal of Child and Adolescent Psychopharmacology

Abstract

This selective review provides a model of the neurobiology of impulsive aggression from a cognitive neuroscience perspective. It is argued that prototypical cases of impulsive aggression, those associated with anger, involve the recruitment of the acute threat response system structures; that is, the amygdala, hypothalamus, and periaqueductal gray. It is argued that whether the recruitment of these structures results in impulsive aggression or not reflects the functional roles of ventromedial frontal cortex and dorsomedial frontal and anterior insula cortex in response selection. It is also argued that impulsive aggression may occur because of impaired decision making. The aggression may not be accompanied by anger, but it will reflect disrupted evaluation of the rewards/benefits of the action.

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Crossref · 10.1089/cap.2015.0088

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71 of 71 references verified0 citation errors · 0 not checkable

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Authors
Blair, R. J. R.
Affiliations
National Institutes of Health
Venue
Journal of Child and Adolescent Psychopharmacology
Published
2016-02
Volume
26
Issue
1
Pages
4-9
ISSN
  • 1044-5463 (ISSN-L)
  • 1557-8992
OpenAlex
W2245990605
Cited by
235
References
71
Citations by year
2026: 23 · 2025: 25 · 2024: 29 · 2023: 31 · 2022: 20 · 2021: 36 · 2020: 28 · 2019: 15 · 2018: 13 · 2017: 9 · 2016: 5 · 2013: 1
FWCI
5.41
Type
journal article
Language
en
Open access
Locations
  • Journal of Child and Adolescent Psychopharmacology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health
  • National Institute of Mental Health (1-ZIA-MH002860, 1‑ZIA‑MH002860‑08, ZIAMH002860)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
  • Social Sciences › Psychology › Social Psychology › Bullying, Victimization, and Aggression
Keywords
impulsive aggression, neurobiology of aggression, amygdala, hypothalamus, periaqueductal gray, ventromedial prefrontal cortex, dorsomedial prefrontal cortex, anterior insula, response selection, decision-making, reward evaluation, anger
MeSH terms
Aggression, Brain, Humans, Impulsive Behavior, Neurobiology

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