Human cortical gustatory areas: A review of functional neuroimaging data

Small, Dana M.; Zald, David H.; Jones-Gotman, Marilyn; Zatorre, Robert J.; Pardo, José V.; Frey, Stephen; Petrides, Michael

doi:10.1097/00001756-199901180-00002

Cited by 431Olfactory and Sensory Function StudiesBiochemical Analysis and Sensing TechniquesTactile and Sensory Interactions

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Human cortical gustatory areas: A review of functional neuroimaging data

Small, Dana M., Zald, David H., Jones-Gotman, Marilyn, Zatorre, Robert J., Pardo, José V., Frey, Stephen, Petrides, Michael·1999·NeuroReport

DOI 10.1097/00001756-199901180-00002

Open this paper in CoChat — free account

Abstract

In an effort to define human cortical gustatory areas we reviewed functional neuroimaging data for which coordinates standardized in Talairach proportional space were available. We observed a wide distribution of peaks within the insula and parietal and frontal opercula, suggesting multiple gustatory regions within this cortical area. Multiple peaks also emerged in the orbitofrontal cortex. However, only two peaks, both in the right hemisphere, were observed in the caudolateral orbitofrontal cortex, the region likely homologous to the secondary taste area described in monkeys. Overall significantly more peaks originated from the right hemisphere suggesting asymmetrical cortical representation of taste favoring the right hemisphere.

Integrity signals

Registry

Crossref · 10.1097/00001756-199901180-00002

Cites

15 of 15 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

In humans, taste is first projected from the tongue and oral cavity to the primary taste cortex in the anterior insula and frontal operculum, along with oral texture and temperature.
“In humans, taste is first projected from the tongue and oral cavity to the primary taste cortex in an area of the anterior insula and frontal operculum (see References [142,143] for reviews), along with oral texture and temperature [144,145].”
From The Role of Intrinsic and Extrinsic Sensory Factors in Sweetness Perception of Food and Beverages: A Review (2019) · cites this paper as [143]
Taste-induced changes in neuronal activation occur within several areas of the human insular and orbitofrontal cortex and preferentially in the right hemisphere.
“Also by fMRI measurement, it was shown that taste-induced changes in neuronal activation occurred within several areas of the human insular and orbitofrontal cortex and preferentially in the right hemisphere”
From Food reward, hyperphagia, and obesity (2011) · cites this paper as [164]

SOMATIC MOTOR AND SENSORY REPRESENTATION IN THE CEREBRAL CORTEX OF MAN AS STUDIED BY ELECTRICAL STIMULATION
PENFIELD, W., & BOLDREY, E. (1937) · Brain · doi:10.1093/brain/60.4.389 · Cited by 4,188
The orbitofrontal cortex
Rolls, E. T. (1996) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1996.0128 · Cited by 755
THE INSULA: FURTHER OBSERVATIONS ON ITS FUNCTION
PENFIELD, W., & FAULK, M. E. (1955) · Brain · doi:10.1093/brain/78.4.445 · Cited by 606
Gustatory responses of single neurons in the caudolateral orbitofrontal cortex of the macaque monkey
Rolls, E. T., Yaxley, S., & Sienkiewicz, Z. J. (1990) · Journal of Neurophysiology · doi:10.1152/jn.1990.64.4.1055 · Cited by 282
Tactile-Vibration-Activated Foci in Insular and Parietal-Opercular Cortex Studied with Positron Emission Tomography: Mapping the Second Somatosensory Area in Humans
Burton, H., Videen, T. O., & Raichle, M. E. (1993) · Somatosensory & Motor Research · doi:10.3109/08990229309028839 · Cited by 271
Gustatory responses of single neurons in the insula of the macaque monkey
Yaxley, S., Rolls, E. T., & Sienkiewicz, Z. J. (1990) · Journal of Neurophysiology · doi:10.1152/jn.1990.63.4.689 · Cited by 262
Afferent connections of the caudolateral orbitofrontal cortex taste area of the primate
Baylis, L. L., Rolls, E. T., & Baylis, G. C. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00449-f · Cited by 217
The architecture of the cortical taste nerve areas in squirrel monkey (Saimiri sciureus) and their relationships to insular, sensorimotor and prefrontal regions
Sanides, F. (1968) · Brain Research · doi:10.1016/0006-8993(68)90174-1 · Cited by 178
GUSTATORY HALLUCINATIONS IN EPILEPTIC SEIZURES
Hausser‐Hauw, C., & Bancaud, J. (1987) · Brain · doi:10.1093/brain/110.2.339 · Cited by 147
Gustatory cortex of primates: anatomy and physiology
Ogawa, H. (1994) · Neuroscience Research · doi:10.1016/0168-0102(94)90017-5 · Cited by 144
Cortical Representation of Taste in Man and Monkey: II. The Localization of the Cortical Taste Area in Man and a Method of Measuring Impairment of Taste in Man.
Börnstein, W. S. (1940) · PubMed · Cited by 105
Ictal clinical manifestations of complex partial seizures.
Dd, D. (1975) · PubMed · Cited by 67
Cortical Representation of Taste in Man and Monkey: I. Functional and Anatomical Relations of Taste, Olfaction, and Somatic Sensibility.
Börnstein, W. S. (1940) · PubMed · Cited by 56
Gustatory and second sensory seizures associated with lesions in the insular cortex seen on magnetic resonance imaging
Cascino, G. D., & Karnes, W. E. (1990) · Journal of Epilepsy · doi:10.1016/0896-6974(90)90044-y · Cited by 33
Connectional networks within the orbital and medial prefrontal cortex of macaque monkeys
Carmichael, S. T., & Price, J. L. (1996) · Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960722)371:2

Flagged first, then by citations

Research works printed but not linked: 3

1940, Yale J Biol Med, 12, 719
1940, Yale J Biol Med, 13, 133
1975, Adv Neurol, 11, 57

Sorted by citations

Functional neuroanatomy of emotion: A meta-analysis of emotion activation studies in PET and fMRI
Phan, K. L., Wager, T., Taylor, S. F., & Liberzon, I. (2002) · NeuroImage · doi:10.1006/nimg.2002.1087 · Cited by 3,502
The human orbitofrontal cortex: linking reward to hedonic experience
Kringelbach, M. L. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1747 · Cited by 2,180
Functional imaging of brain responses to pain. A review and meta-analysis (2000)
Peyron, R., Laurent, B., & García-Larrea, L. (2000) · Neurophysiologie Clinique/Clinical Neurophysiology · doi:10.1016/s0987-7053(00)00227-6 · Cited by 2,171
Neurobiology of emotion perception I: the neural basis of normal emotion perception
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00168-9 · Cited by 2,173
The functional neuroanatomy of the human orbitofrontal cortex: Evidence from neuroimaging and neuropsychology
KRINGELBACH, M. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.03.006 · Cited by 1,977
Simulating Minds
Goldman, A. I. (2006) · doi:10.1093/0195138929.001.0001 · Cited by 1,522
A link between the systems: functional differentiation and integration within the human insula revealed by meta-analysis
Kurth, F., Zilles, K., Fox, P. T., Laird, A. R., & Eickhoff, S. B. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0255-z · Cited by 1,293
The functions of the orbitofrontal cortex
Rolls, E. T. (2004) · Brain and Cognition · doi:10.1016/s0278-2626(03)00277-x · Cited by 1,327
Changes in brain activity related to eating chocolate: From pleasure to aversion
Small, D. M. (2001) · Brain · doi:10.1093/brain/124.9.1720 · Cited by 1,179
Self-citation
Encoding Predictive Reward Value in Human Amygdala and Orbitofrontal Cortex
Gottfried, J. A., O'Doherty, J., & Dolan, R. J. (2003) · Science · doi:10.1126/science.1087919 · Cited by 1,165
Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimaging
Wager, T. D., Phan, K. L., Liberzon, I., & Taylor, S. F. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00078-8 · Cited by 1,150
Functional neuroanatomy of emotions: A meta-analysis
MURPHY, F. C., NIMMO-SMITH, I., & LAWRENCE, A. D. (2003) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.3.3.207 · Cited by 1,135
Disgust as a disease-avoidance mechanism.
Oaten, M., Stevenson, R. J., & Case, T. I. (2009) · Psychological Bulletin · doi:10.1037/a0014823 · Cited by 1,120
Neural responses during anticipation of a primary taste reward
O'Doherty, J. P., Deichmann, R., Critchley, H. D., & Dolan, R. J. (2002) · Neuron · doi:10.1016/s0896-6273(02)00603-7 · Cited by 1,076
Neuropsychology of fear and loathing
Calder, A. J., Lawrence, A. D., & Young, A. W. (2001) · Nature reviews. Neuroscience · doi:10.1038/35072584 · Cited by 927
Widespread reward-system activation in obese women in response to pictures of high-calorie foods
Stoeckel, L. E., Weller, R. E., Cook, E. W., Twieg, D. B., Knowlton, R. C., & Cox, J. E. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.02.031 · Cited by 857
Activation of the Human Orbitofrontal Cortex to a Liquid Food Stimulus is Correlated with its Subjective Pleasantness
Kringelbach, M. L. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.10.1064 · Cited by 824
The orbitofrontal cortex and beyond: From affect to decision-making
Rolls, E. T., & Fabian Grabenhorst, B. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.09.001 · Cited by 848
Dissociation of Neural Representation of Intensity and Affective Valuation in Human Gustation
Small, D. M., Gregory, M. D., Mak, Y. E., Gitelman, D. R., Mesulam, M. M., & Parrish, T. B. (2003) · Neuron · doi:10.1016/s0896-6273(03)00467-7 · Cited by 812
Self-citation
Three systems of insular functional connectivity identified with cluster analysis
Deen, B., Pitskel, N. B., & Pelphrey, K. A. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq186 · Cited by 716
Multiple neural systems controlling food intake and body weight
Berthoud, H.-R. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00014-3 · Cited by 725
Odor/taste integration and the perception of flavor
Small, D. M., & Prescott, J. (2005) · Experimental Brain Research · doi:10.1007/s00221-005-2376-9 · Cited by 712
Self-citation
Differential activation of the dorsal striatum by high-calorie visual food stimuli in obese individuals
Rothemund, Y., Preuschhof, C., Bohner, G., Bauknecht, H.-C., Klingebiel, R., Flor, H., & Klapp, B. F. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.05.008 · Cited by 679
Representation of Pleasant and Aversive Taste in the Human Brain
O’Doherty, J. P., Rolls, E. T., Francis, S., Bowtell, R. W., & McGlone, F. P. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.3.1315 · Cited by 688
Taste‐olfactory convergence, and the representation of the pleasantness of flavour, in the human brain
De Araujo, I. E. T., Rolls, E. T., Kringelbach, M. L., McGlone, F., & Phillips, N. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02915.x · Cited by 642
Dissociating valence of outcome from behavioral control in human orbital and ventral prefrontal cortices
O'Doherty, J., Critchley, H., Deichmann, R., & Dolan, R. J. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-21-07931.2003 · Cited by 611
Impaired recognition and experience of disgust following brain injury
Calder, A. J., Keane, J., Manes, F., Antoun, N., & Young, A. W. (2000) · Nature Neuroscience · doi:10.1038/80586 · Cited by 850
Reward-related reversal learning after surgical excisions in orbito-frontal or dorsolateral prefrontal cortex in humans
Hornak, J., O'Doherty, J., Bramham, J., Rolls, E. T., Morris, R. G., Bullock, P. R., & Polkey, C. E. (2004) · Journal of Cognitive Neuroscience · doi:10.1162/089892904322926791 · Cited by 603
Pictures of appetizing foods activate gustatory cortices for taste and reward
Simmons, W. K., Martin, A., & Barsalou, L. W. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhi038 · Cited by 569
Representations of Pleasant and Painful Touch in the Human Orbitofrontal and Cingulate Cortices
Rolls, E. T. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.3.308 · Cited by 535
Neurophysiology of swallowing
Erteki̇n, C., & Aydoğdu, İ. (2003) · Clinical Neurophysiology · doi:10.1016/s1388-2457(03)00237-2 · Cited by 539
Changes in appetite, food preference, and eating habits in frontotemporal dementia and Alzheimer's disease
Ikeda, M. (2002) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.73.4.371 · Cited by 499
Differential neural responses evoked by orthonasal versus retronasal odorant perception in humans
Small, D. M., Gerber, J. C., Mak, Y. E., & Hummel, T. (2005) · Neuron · doi:10.1016/j.neuron.2005.07.022 · Cited by 463
Self-citation
Simulationist models of face-based emotion recognition
Goldman, A. I., & Sripada, C. S. (2005) · Cognition · doi:10.1016/j.cognition.2004.01.005 · Cited by 647
Evidence for mirror systems in emotions
Bastiaansen, J. A., Thioux, M., & Keysers, C. (2009) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2009.0058 · Cited by 444
Exposure to appetitive food stimuli markedly activates the human brain
Wang, G.-J., Volkow, N. D., Telang, F., Jayne, M., Ma, J., Rao, M., Zhu, W., Wong, C. T., Pappas, N. R., Geliebter, A., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.11.026 · Cited by 402
Experience-dependent neural integration of taste and smell in the human brain
Small, D. M., Voss, J., Mak, Y. E., Simmons, K. B., Parrish, T., & Gitelman, D. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00050.2004 · Cited by 398
Self-citation
The neurocognitive bases of human multimodal food perception: Sensory integration
Verhagen, J. V., & Engelen, L. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.11.003 · Cited by 411
Naturalizing aesthetics: Brain areas for aesthetic appraisal across sensory modalities
Brown, S., Gao, X., Tisdelle, L., Eickhoff, S. B., & Liotti, M. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.012 · Cited by 376
The impact of sleep deprivation on food desire in the human brain
Greer, S. M., Goldstein, A. N., & Walker, M. P. (2013) · Nature Communications · doi:10.1038/ncomms3259 · Cited by 375
An analysis of rat prefrontal cortex in mediating executive function
Kesner, R. P., & Churchwell, J. C. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.07.002 · Cited by 365
Representation in the Human Brain of Food Texture and Oral Fat
de Araujo, I. E., & Rolls, E. T. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.0130-04.2004 · Cited by 365
fMRI of emotional responses to odors:
Royet, J., Plailly, J., Delon‐Martin, C., Kareken, D. A., & Segebarth, C. M. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00388-4 · Cited by 374
How cognition modulates affective responses to taste and flavor: top-down influences on the orbitofrontal and pregenual cingulate cortices
Grabenhorst, F., Rolls, E. T., & Bilderbeck, A. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm185 · Cited by 337
The orbitofrontal cortex and emotion in health and disease, including depression
Rolls, E. T. (2017) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.09.021 · Cited by 341
Things rank and gross in nature: A review and synthesis of moral disgust.
Chapman, H. A., & Anderson, A. K. (2013) · Psychological Bulletin · doi:10.1037/a0030964 · Cited by 342
Population coding of affect across stimuli, modalities and individuals
Chikazoe, J., Lee, D. H., Kriegeskorte, N., & Anderson, A. K. (2014) · Nature Neuroscience · doi:10.1038/nn.3749 · Cited by 321
Strokes restricted to the insular cortex
Cereda, C., Ghika, J., Maeder, P., & Bogousslavsky, J. (2002) · Neurology · doi:10.1212/01.wnl.0000038905.75660.bd · Cited by 302
The neurobiology of food intake in an obesogenic environment
Berthoud, H. (2012) · Proceedings of The Nutrition Society · doi:10.1017/s0029665112000602 · Cited by 320
Taste representation in the human insula
Small, D. M. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0266-9 · Cited by 300
Self-citation
Volumetric neuroimaging investigations in mood disorders: bipolar disorder versus major depressive disorder
Konarski, J. Z., McIntyre, R. S., Kennedy, S. H., Rafi‐Tari, S., Soczynska, J. K., & Ketter, T. A. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00435.x · Cited by 311
Taste, olfactory, and food reward value processing in the brain
Rolls, E. T. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.03.002 · Cited by 306
Probabilistic tractography recovers a rostrocaudal trajectory of connectivity variability in the human insular cortex
Cerliani, L., Thomas, R. M., Jbabdi, S., Siero, J. C. W., Nanetti, L., Crippa, A., Gazzola, V., D'Arceuil, H. E., & Keysers, C. (2011) · Human Brain Mapping · doi:10.1002/hbm.21338 · Cited by 297
Food reward, hyperphagia, and obesity
Berthoud, H.-R., Lenard, N. R., & Shin, A. C. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00028.2011 · Cited by 275
On the scent of human olfactory orbitofrontal cortex: Meta-analysis and comparison to non-human primates
Gottfried, J. A., & Zald, D. H. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.08.004 · Cited by 281
Self-citation
Representation of Umami Taste in the Human Brain
de Araujo, I. E. T., Kringelbach, M. L., Rolls, E. T., & Hobden, P. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00669.2002 · Cited by 254
Binge eating is associated with right orbitofrontal-insular-striatal atrophy in frontotemporal dementia
Woolley, J. D., Gorno‐Tempini, M., Seeley, W. W., Rankin, K. P., Lee, S. S., Matthews, B. R., & Miller, B. L. (2007) · Neurology · doi:10.1212/01.wnl.0000277461.06713.23 · Cited by 254
Activation of anterior paralimbic structures during guilt-related script-driven imagery
Shin, L. M., Dougherty, D. D., Orr, S. P., Pitman, R. K., Lasko, M., Macklin, M. L., Alpert, N. M., Fischman, A. J., & Rauch, S. L. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00251-1 · Cited by 252
Involvement of Human Amygdala and Orbitofrontal Cortex in Hunger-Enhanced Memory for Food Stimuli
Morris, J., & Dolan, R. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05304.2001 · Cited by 242
Food for thought: hedonic experience beyond homeostasis in the human brain
Kringelbach, M. L. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.04.035 · Cited by 236
Attention biases, anxiety, and development: toward or away from threats or rewards?
Shechner, T., Britton, J. C., Pérez‐Edgar, K. E., Bar‐Haim, Y., Ernst, M., Fox, N. A., Leibenluft, E., & Pine, D. S. (2011) · Depression and Anxiety · doi:10.1002/da.20914 · Cited by 252
Clinical effects of insular damage in humans
Ibañez, A., Gleichgerrcht, E., & Manes, F. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0256-y · Cited by 217
Ictal clinical and scalp-EEG findings differentiating temporal lobe epilepsies from temporal 'plus' epilepsies
Barba, C., Barbati, G., Minotti, L., Hoffmann, D., & Kahane, P. (2007) · Brain · doi:10.1093/brain/awm108 · Cited by 221
Umami: a delicious flavor formed by convergence of taste and olfactory pathways in the human brain
McCabe, C., & Rolls, E. T. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05445.x · Cited by 221
How the Brain Represents the Reward Value of Fat in the Mouth
Fabian Grabenhorst, B., Rolls, E. T., Parris, B. A., & D’Souza, A. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp169 · Cited by 210
Interaction of gustatory and lingual somatosensory perceptions at the cortical level in the human: A functional magnetic resonance imaging study
Cerf-Ducastel, B. (2001) · Chemical Senses · doi:10.1093/chemse/26.4.371 · Cited by 207
Selective attention to affective value alters how the brain processes taste stimuli
Fabian Grabenhorst, B., & Rolls, E. T. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06033.x · Cited by 216
Altering expectancy dampens neural response to aversive taste in primary taste cortex
Nitschke, J. B., Dixon, G. E., Sarinopoulos, I., Short, S. J., Cohen, J. D., Smith, E. E., Kosslyn, S. M., Rose, R. M., & Davidson, R. J. (2006) · Nature Neuroscience · doi:10.1038/nn1645 · Cited by 199
Identification of human gustatory cortex by activation likelihood estimation
Veldhuizen, M. G., Albrecht, J., Zelano, C., Boesveldt, S., Breslin, P. A. S., & Lundström, J. N. (2011) · Human Brain Mapping · doi:10.1002/hbm.21188 · Cited by 195
Color of Scents: Chromatic Stimuli Modulate Odor Responses in the Human Brain
Österbauer, R. A., Matthews, P. M., Jenkinson, M., Beckmann, C. F., Hansen, P. C., & Calvert, G. A. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00555.2004 · Cited by 193
Persistence of abnormal neural responses to a meal in postobese individuals
DelParigi, A., Chen, K., Salbe, A. D., Hill, J. O., Wing, R. R., Reiman, E. M., & Tataranni, P. A. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802558 · Cited by 189
Trying to detect taste in a tasteless solution: modulation of early gustatory cortex by attention to taste.
Veldhuizen, M., Bender, G., Constable, R. T., & Small, D. (2007) · Chemical Sensors · doi:10.1093/chemse/bjm025 · Cited by 179
Self-citation
Statistical localization of human olfactory cortex
Seubert, J., Freiherr, J., Djordjevic, J., & Lundström, J. N. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.10.030 · Cited by 190
Separable Substrates for Anticipatory and Consummatory Food Chemosensation
Small, D. M., Veldhuizen, M. G., Felsted, J. A., Mak, Y. E., & McGlone, F. P. (2008) · Neuron · doi:10.1016/j.neuron.2008.01.021 · Cited by 190
Self-citation
Primate Insular/Opercular Taste Cortex: Neuronal Representations of the Viscosity, Fat Texture, Grittiness, Temperature, and Taste of Foods
Verhagen, J. V., Kadohisa, M., & Rolls, E. T. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00321.2004 · Cited by 189
Patients with Schizophrenia have a Reduced Neural Response to Both Unpredictable and Predictable Primary Reinforcers
Waltz, J. A., Schweitzer, J. B., Gold, J. M., Kurup, P. K., Ross, T. J., Jo Salmeron, B., Rose, E. J., McClure, S. M., & Stein, E. A. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.214 · Cited by 186
Overlapping Responses for the Expectation of Juice and Money Rewards in Human Ventromedial Prefrontal Cortex
Kim, H., Shimojo, S., & O'Doherty, J. P. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq145 · Cited by 176
Food related processes in the insular cortex
Frank, S., Kullmann, S., & Veit, R. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00499 · Cited by 186
Cerebral cortex : principles of operation
Rolls, E. T. (2016) · doi:10.82444/warw.33712699 · Cited by 187
Neuroanatomy of cells expressing clock genes inDrosophila: Transgenic manipulation of theperiod andtimeless genes to mark the perikarya of circadian pacemaker neurons and their projections
Kaneko, M. A. N., & Hall, J. C. (2000) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(20000619)422:1 · Cited by 391
Self-citation
fMRI Activation in Response to Odorants Orally Delivered in Aqueous Solutions
Cerf-Ducastel, B. (2001) · Chemical Senses · doi:10.1093/chemse/26.6.625 · Cited by 179
Neuroanatomic Correlates of Psychopathologic Components of Major Depressive Disorder
Milak, M. S., Parsey, R. V., Keilp, J. G., Oquendo, M. A., Malone, K. M., & Mann, J. J. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.4.397 · Cited by 178
Neuronal Representations of Stimuli in the Mouth: The Primate Insular Taste Cortex, Orbitofrontal Cortex and Amygdala
Kadohisa, M., Rolls, E. T., & Verhagen, J. V. (2005) · Chemical Senses · doi:10.1093/chemse/bji036 · Cited by 173
Neural Correlates of Tasting Concentrated Quinine and Sugar Solutions
Zald, D. H., Hagen, M. C., & Pardo, J. V. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00358.2001 · Cited by 172
Self-citation
Cognitive and behavioral profile in a case of right anterior temporal lobe neurodegeneration
Gorno-Tempini, M. L., Rankin, K. P., Woolley, J. D., Rosen, H. J., Phengrasamy, L., & Miller, B. L. (2004) · Cortex · doi:10.1016/s0010-9452(08)70159-x · Cited by 164
The Role of Intrinsic and Extrinsic Sensory Factors in Sweetness Perception of Food and Beverages: A Review
Wang, Q. J., Mielby, L. A., Junge, J. Y., Bertelsen, A. S., Kidmose, U., Spence, C., & Byrne, D. V. (2019) · Foods · doi:10.3390/foods8060211 · Cited by 168
Convergence of sensory systems in the orbitofrontal cortex in primates and brain design for emotion.
Rolls, E. (2004) · Anatomical Record Part A-discoveries in Molecular Cellular and Evolutionary Biology · doi:10.1002/ar.a.20126 · Cited by 170
Sensory experience of food and obesity: a positron emission tomography study of the brain regions affected by tasting a liquid meal after a prolonged fast
DelParigi, A., Chen, K., Salbe, A. D., Reiman, E. M., & Tataranni, P. A. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.08.035 · Cited by 158
Disgust sensitivity predicts the insula and pallidal response to pictures of disgusting foods.
Calder, A. J., Beaver, J. D., Davis, M. H., Van Ditzhuijzen, J., Keane, J., & Lawrence, A. D. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05604.x · Cited by 154
Functions of the anterior insula in taste, autonomic, and related functions
Rolls, E. T. (2015) · Brain and Cognition · doi:10.1016/j.bandc.2015.07.002 · Cited by 165
Representations of the texture of food in the primate orbitofrontal cortex: neurons responding to viscosity, grittiness, and capsaicin.
Rolls, E., Verhagen, J. V., & Kadohisa, M. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00515.2003 · Cited by 164
Taste-related activity in the human dorsolateral prefrontal cortex
Kringelbach, M. L., de Araújo, I. E., & Rolls, E. T. (2003) · NeuroImage · doi:10.1016/j.neuroimage.2003.09.063 · Cited by 156
Functional magnetic resonance tomography correlates of taste perception in the human primary taste cortex
Schoenfeld, M. A., Neuer, G., Tempelmann, C., Schüßler, K., Noesselt, T., Hopf, J., & Heinze, H. –. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.05.024 · Cited by 154
CEREBRE: A Novel Method for Very High Accuracy Event-Related Potential Biometric Identification
Ruiz-Blondet, M. V., Jin, Z., & Laszlo, S. (2016) · IEEE Transactions on Information Forensics and Security · doi:10.1109/tifs.2016.2543524 · Cited by 152
The neuropsychological impact of insular cortex lesions
Jones, C. L., Ward, J., & Critchley, H. D. (2010) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2009.193672 · Cited by 158
The gustatory cortex and multisensory integration
de Araujo, I. E., & Simon, S. A. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.70 · Cited by 150
Crossmodal plasticity in sensory loss
Frasnelli, J., Collignon, O., Voss, P., & Leporé, F. (2011) · Progress in brain research · doi:10.1016/b978-0-444-53752-2.00002-3 · Cited by 166
An expanded view of energy homeostasis: Neural integration of metabolic, cognitive, and emotional drives to eat
Shin, A. C., Zheng, H., & Berthoud, H. (2009) · Physiology & Behavior · doi:10.1016/j.physbeh.2009.02.010 · Cited by 153
Hungry brains: A meta-analytical review of brain activation imaging studies on food perception and appetite in obese individuals
Devoto, F., Zapparoli, L., Bonandrini, R., Berlingeri, M., Ferrulli, A., Luzi, L., Banfi, G., & Paulesu, E. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.07.017 · Cited by 140
Influence of taste disorders on dietary behaviors in cancer patients under chemotherapy
Sánchez-Lara, K., Sosa-Sánchez, R., Green-Renner, D., Rodríguez, C., Laviano, A., Motola‐Kuba, D., & Arrieta, O. G. (2010) · Nutrition Journal · doi:10.1186/1475-2891-9-15 · Cited by 147

Brain imaging: Human cortical gustatory areas: A review of functional neuroimaging data
Small, D. M., Zald, D. H., Jones‐Gotman, M., Zatorre, R. J., Pardo, J. V., Frey, S., & Petrides, M. (1999) · Cited by 5
Self-citation
Functional Organization of the Human Gustatory Cortex
Kobayashi, M. (2006) · Journal of Oral Biosciences · doi:10.1016/s1349-0079(06)80007-1 · Cited by 14
Identification of human gustatory cortex by activation likelihood estimation
Veldhuizen, M. G., Albrecht, J., Zelano, C., Boesveldt, S., Breslin, P. A. S., & Lundström, J. N. (2011) · Human Brain Mapping · doi:10.1002/hbm.21188 · Cited by 195
Gustatory cortex of primates: anatomy and physiology
Ogawa, H. (1994) · Neuroscience Research · doi:10.1016/0168-0102(94)90017-5 · Cited by 144
SUMMARY AND CONCLUSIONS
Rolls, E. T., Yaxley, S., Zenon, & Sienkiewicz, J. (2008)

Authors: Small, D. M., Zald, D. H., Jones-Gotman, M., Zatorre, R. J., Pardo, J. V., Frey, S., & Petrides, M.
Affiliations: Montreal Neurological Institute and Hospital (CA)
Minneapolis VA Medical Center (US)
ORCID: Small, Dana M.
Zald, David H.
Zatorre, Robert J.
Pardo, José V.
Petrides, Michael
Venue: NeuroReport
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1999-01
Volume: 10
Issue: 1
Pages: 7-13
ISSN: 0959-4965 (ISSN-L)
DOI: 10.1097/00001756-199901180-00002
OpenAlex: W1998229361
Cited by: 431
References: 15
Citations by year: 2026: 4 · 2025: 3 · 2024: 4 · 2023: 5 · 2022: 6 · 2021: 12 · 2020: 11 · 2019: 13 · 2018: 19 · 2017: 15 · 2016: 17 · 2015: 18 · 2014: 13 · 2013: 18 · 2012: 25
FWCI: 6.86
Type: journal article
Language: en
Open access: closed
Locations: Neuroreport (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (MH1 1641-01A1)
Topics: Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
Keywords: gustatory cortex, insula, operculum, orbitofrontal cortex, hemispheric lateralization, functional neuroimaging, Talairach coordinates
MeSH terms: Brain Mapping, Cerebral Cortex, Frontal Lobe, Humans, Magnetic Resonance Imaging, Parietal Lobe, Taste, Tomography, Emission-Computed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Human cortical gustatory areas: A review of functional neuroimaging data

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks