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Cited by 419

The DOI matches its Crossref record; 249 of the 249 references it cites were found in a registry or an index.

The Sertoli cell: one hundred fifty years of beauty and plasticity

Open access
França, L. R., Hess, R. A., Dufour, J. M., Hofmann, M. C., Griswold, M. D.·2016·Andrology

Abstract

Summary: It has been one and a half centuries since Enrico Sertoli published the seminal discovery of the testicular ‘nurse cell’, not only a key cell in the testis, but indeed one of the most amazing cells in the vertebrate body. In this review, we begin by examining the three phases of morphological research that have occurred in the study of Sertoli cells, because microscopic anatomy was essentially the only scientific discipline available for about the first 75 years after the discovery. Biochemistry and molecular biology then changed all of biological sciences, including our understanding of the functions of Sertoli cells. Immunology and stem cell biology were not even topics of science in 1865, but they have now become major issues in our appreciation of Sertoli cell's role in spermatogenesis. We end with the universal importance and plasticity of function by comparing Sertoli cells in fish, amphibians, and mammals. In these various classes of vertebrates, Sertoli cells have quite different modes of proliferation and epithelial maintenance, cystic vs. tubular formation, yet accomplish essentially the same function but in strikingly different ways.

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Crossref · 10.1111/andr.12165

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Metadata

Authors
França, L. R., Hess, R. A., Dufour, J. M., Hofmann, M. C., & Griswold, M. D.
Venue
Andrology
Publisher
Wiley
Published
2016-02-04
Volume
4
Issue
2
Pages
189-212
ISSN
  • 2047-2919 (ISSN-L)
  • 2047-2927
OpenAlex
W2286124328
Cited by
419
References
249
FWCI
38.58
Type
journal article
Language
en
Open access
hybrid

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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