Attention to pain localization and unpleasantness discriminates the functions of the medial and lateral pain systems.
Abstract
Functional imaging studies have identified a matrix of structures in the brain that respond to noxious stimuli. Within this matrix, a division of function between sensory-discriminative and affective responses has so far been demonstrated by manipulating either pain intensity or unpleasantness under hypnosis in two different normal volunteer groups studied on separate occasions. Our study used positron emission tomography (PET) to demonstrate this division of function under more natural conditions in a healthy group of volunteers, using a CO(2) laser to provide nociceptive stimuli that selectively activate A-delta and C-fibres without contamination by touch sensations. We measured the differential cerebral responses to noxious and innocuous laser stimuli during conditions of selective attention to either the unpleasantness or location of the stimuli. Attention to location increased responses in the contralateral (right) primary somatosensory and inferior parietal cortices. This result implies that these components of the lateral pain system are concerned mainly with the localization of pain. In contrast, attention to unpleasantness increased responses in bilateral perigenual cingulate and orbitofrontal cortices, contralateral (right) amygdala, ipsilateral (left) hypothalamus, posterior insula, M1 and frontal pole. These areas comprise key components of the medial pain and neuroendocrine systems and the results suggest that they have a role in the affective response to pain. Our results indicate the importance of attentional effects on the pattern of nociceptive processing in the brain. They also provide the first clear demonstration, within a single experiment, of a major division of function within the neural pain matrix.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Directing attention can increase neural activity in the somatosensory-discriminative component of pain processing.
“Thus, it seems that directing attention (a top-down influence rather than an automatic reaction) can increase the neural activity in somatosensory-discriminative component of pain processing.”
From What are you feeling? Using functional magnetic resonance imaging to assess the modulation of sensory and affective responses during empathy for pain (2007) · cites this paper as [19]
Cites
Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688 · see citing works
Self-citationThe attention system of the human brain
Posner, M. I., & Petersen, S. E. (1990) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.13.030190.000325 · Cited by 8,070 · cited 1× · see citing works
“The MCC is also an important component of the anterior attentional system (Posner & Petersen, 1990; Bush et al., 2000), although nociceptive responses appear to locate to discrete areas that are distinct from those concerned with these more general attentional functions (Derbyshire et al., 1998).”
BackgroundCognitive and emotional influences in anterior cingulate cortex
Bush, G., Luu, P., & Posner, M. I. (2000) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01483-2 · Cited by 6,259 · see citing works
Empathy for Pain Involves the Affective but not Sensory Components of Pain
Singer, T., Seymour, B., O'Doherty, J., Kaube, H., Dolan, R. J., & Frith, C. D. (2004) · Science · doi:10.1126/science.1093535 · Cited by 3,929 · see citing works
Contributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377 · see citing works
Large-scale neurocognitive networks and distributed processing for attention, language, and memory
Mesulam, M. (1990) · Annals of Neurology · doi:10.1002/ana.410280502 · Cited by 2,684 · see citing works
Pain Affect Encoded in Human Anterior Cingulate But Not Somatosensory Cortex
Rainville, P., Duncan, G. H., Price, D. D., Carrier, B., & Bushnell, M. C. (1997) · Science · doi:10.1126/science.277.5328.968 · Cited by 2,629 · see citing works
Functional imaging of brain responses to pain. A review and meta-analysis (2000)
Peyron, R., Laurent, B., & García-Larrea, L. (2000) · Neurophysiologie Clinique/Clinical Neurophysiology · doi:10.1016/s0987-7053(00)00227-6 · Cited by 2,171 · see citing works
Placebo and Opioid Analgesia-- Imaging a Shared Neuronal Network
Petrovic, P., Kalso, E., Petersson, K. M., & Ingvar, M. (2002) · Science · doi:10.1126/science.1067176 · Cited by 1,488 · see citing works
Human Experimentation: Code of Ethics of W.M.A
RICKHAM, P. P. (1964) · BMJ · doi:10.1136/bmj.2.5402.177 · Cited by 1,457 · see citing works
Neuroimaging studies of mood disorders
Drevets, W. C. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01020-9 · Cited by 1,313 · see citing works
Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys
Carmichael, S. T., & Price, J. L. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903630408 · Cited by 1,197 · see citing works
The cortical representation of pain
Treede, R.-D., Kenshalo, D. R., Gracely, R. H., & Jones, A. K. P. (1999) · Pain · doi:10.1016/s0304-3959(98)00184-5 · Cited by 1,077 · see citing works
Self-citationPain intensity processing within the human brain: a bilateral, distributed mechanism
Coghill, R. C., Sang, C. N., Maisog, J. M., & Iadarola, M. J. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.82.4.1934 · Cited by 1,077 · see citing works
Imaging how attention modulates pain in humans using functional MRI
Bantick, S. J., Wise, R. G., Ploghaus, A., Clare, S., Smith, S. M., & Tracey, I. (2002) · Brain · doi:10.1093/brain/awf022 · Cited by 888 · see citing works
Cingulate cortex of the rhesus monkey: II. Cortical afferents
Vogt, B. A., & Pandya, D. N. (1987) · Journal of Comparative Neurology · doi:10.1002/cne.902620208 · Cited by 854 · see citing works
Valet, M., Sprenger, T., Boecker, H., Willoch, F., Rummeny, E., Conrad, B., Erhard, P., & Tolle, T. R. (2004) · Pain · doi:10.1016/j.pain.2004.02.033 · Cited by 708 · see citing works
Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression
Drevets, W. C. (2000) · Progress in Brain Research · doi:10.1016/s0079-6123(00)26027-5 · Cited by 659 · see citing works
Central representation of chronic ongoing neuropathic pain studied by positron emission tomography
Hsieh, J., Belfrage, M., Stone‐Elander, S., Hansson, P. T., & Ingvar, M. (1995) · Pain · doi:10.1016/0304-3959(95)00048-w · Cited by 636 · see citing works
Derbyshire, S. W. G., Jones, A. K. P., Gyulai, F., Clark, S., Townsend, D., & Firestone, L. L. (1997) · Pain · doi:10.1016/s0304-3959(97)00138-3 · Cited by 629 · see citing works
Self-citationCortical Representation of the Sensory Dimension of Pain
Hofbauer, R. K., Rainville, P., Duncan, G. H., & Bushnell, M. C. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.1.402 · Cited by 611 · cited 3× · see citing works
“Functional imaging studies have attempted to demonstrate this division of function within the pain matrix by attentional manipulations and hypnosis (Rainville et al., 1997; Peyron et al., 1999; Tölle et al., 1999; Hofbauer et al., 2001).”
BackgroundCortical and subcortical afferents to the amygdala of the rhesus monkey (Macaca mulatta)
Aggleton, J. P., Burton, M. J., & Passingham, R. E. (1980) · Brain Research · doi:10.1016/0006-8993(80)90279-6 · Cited by 610 · see citing works
Pain “relief” by frontal cingulumotomy
Foltz, E. L., & White, L. E. (1962) · Journal of Neurosurgery · doi:10.3171/jns.1962.19.2.0089 · Cited by 588 · see citing works
Bornhövd, K., Quante, M., Glauche, V., Bromm, B., Weiller, C., & Büchel, C. (2002) · Brain · doi:10.1093/brain/awf137 · Cited by 584 · see citing works
Haemodynamic brain responses to acute pain in humans
Peyron, R., Garcı́a-Larrea, L., Grégoire, M., Costes, N., Convers, P., Lavenne, F., Mauguı̀ere, F., Michel, D., & Laurent, B. (1999) · Brain · doi:10.1093/brain/122.9.1765 · Cited by 576 · see citing works
Ostrowsky‐Coste, K. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.4.376 · Cited by 573 · see citing works
Brain generators of laser-evoked potentials: from dipoles to functional significance
Garcia-Larrea, L., Frot, M., & Valeriani, M. (2003) · Neurophysiologie Clinique/Clinical Neurophysiology · doi:10.1016/j.neucli.2003.10.008 · Cited by 541 · see citing works
Cortical and subcortical localization of response to pain in man using positron emission tomography
Jones, A. K. P., Brown, W. D., Friston, K. J., Qi, L. Y., & Frackowiak, R. S. J. (1991) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1991.0048 · Cited by 538 · see citing works
Self-citationRepresentations of Pleasant and Painful Touch in the Human Orbitofrontal and Cingulate Cortices
Rolls, E. T. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.3.308 · Cited by 535 · see citing works
Dissociation of sensory and affective dimensions of pain using hypnotic modulation.
Rainville, P., Carrier, B., Hofbauer, R. K., Bushnell, C. M., & Duncan, G. H. (1999) · Pain · doi:10.1016/s0304-3959(99)00048-2 · Cited by 530 · see citing works
Casey, K. L., Minoshima, S., Morrow, T., & Koeppe, R. A. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.76.1.571 · Cited by 477 · see citing works
Does anticipation of pain affect cortical nociceptive systems?
Porro, C. A., Baraldi, P., Pagnoni, G., Serafini, M., Facchin, P., Maieron, M., & Nichelli, P. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-08-03206.2002 · Cited by 469 · see citing works
Paus, T., Koski, L. M., Caramanos, Z., & Westbury, C. F. (1998) · Neuroreport · doi:10.1097/00001756-199806220-00001 · Cited by 460 · see citing works
Somatosensory and auditory convergence in the lateral nucleus of the amygdala.
Romanski, L. M., Clugnet, M.-C., Bordi, F., & LeDoux, J. E. (1993) · Behavioral Neuroscience · doi:10.1037/0735-7044.107.3.444 · Cited by 446 · see citing works
Structural and functional dichotomy of human midcingulate cortex
Vogt, B. A., Berger, G. R., & Derbyshire, S. W. G. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.03034.x · Cited by 440 · see citing works
Self-citationThree‐dimensional reconstruction of the antennal lobe in Drosophila melanogaster
Laissue, P. P., Reiter, C., Hiesinger, P. R., Halter, S., Fischbach, K. F., & Stocker, R. F. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990322)405:4 · Cited by 421 · see citing works
Diencephalic mechanisms of pain sensation
Albe-Fessard, D., Berkley, K. J., Kruger, L., Ralston, H. J., & Willis, W. D. (1985) · Brain Research Reviews · doi:10.1016/0165-0173(85)90013-x · Cited by 407 · see citing works
Büchel, C., Dolan, R. J., Armony, J. L., & Friston, K. J. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-24-10869.1999 · Cited by 404 · see citing works
Self-citationVogt, B. A., Derbyshire, S. W. G., & Jones, A. K. P. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01608.x · Cited by 384 · see citing works
Self-citationBüchel, C., Bornhövd, K., Quante, M., Glauche, V., Bromm, B., & Weiller, C. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-03-00970.2002 · Cited by 380 · see citing works
Neural Mechanisms of Antinociceptive Effects of Hypnosis
Faymonville, M. E., Laureys, S., Degueldre, C., DelFiore, G., Luxen, A., Franck, G., Lamy, M., & Maquet, P. (2000) · Anesthesiology · doi:10.1097/00000542-200005000-00013 · Cited by 370 · see citing works
Projections from the amygdala to basoventral and mediodorsal prefrontal regions in the rhesus monkey
Barbas, H., & de Olmos, J. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.903000409 · Cited by 324 · see citing works
Derbyshire, S. W. G., Jones, A. K. P., Devani, P., Friston, K. J., Feinmann, C., Harris, M., Pearce, S. A., Watson, J. D. G., & Frackowiak, R. S. J. (1994) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.57.10.1166 · Cited by 318 · see citing works
Self-citationTERMINATION OF THE CENTRAL PAIN PATHWAY IN MAN: THE CONSCIOUS APPRECIATION OF PAIN
Bowsher, D. R. (1957) · Brain · doi:10.1093/brain/80.4.606 · Cited by 318 · see citing works
Pain Pathways Involved in Fear Conditioning Measured with Fear-Potentiated Startle: Lesion Studies
Shi, C., & Davis, M. E. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-01-00420.1999 · Cited by 282 · see citing works
Legrain, V., Guérit, J.-M., Bruyer, R., & Plaghki, L. (2002) · Pain · doi:10.1016/s0304-3959(02)00051-9 · Cited by 274 · see citing works
Kwan, C. L., Crawley, A. P., Mikulis, D. J., & Davis, K. D. (2000) · Pain · doi:10.1016/s0304-3959(99)00287-0 · Cited by 259 · see citing works
Central nervous pathways mediating angina pectoris
Rosen, S. D., Paulesu, E., Frith, C., Frackowiak, R. S. J., Davies, G. J., Jones, T., & Camici, P. G. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92755-3 · Cited by 255 · see citing works
Self-citation(1992) · PubMed · Cited by 252 · see citing works
Pain affect without pain sensation in a patient with a postcentral lesion
Ploner, M., Freund, H., & Schnitzler, A. (1999) · Pain · doi:10.1016/s0304-3959(99)00012-3 · Cited by 251 · see citing works
Hsieh, J.-C., Ståhle-Bäckdahl, M., Hägermark, Ö., Stone-Elander, S., Rosenquist, G., & Ingvar, M. (1996) · Pain · doi:10.1016/0304-3959(95)00129-8 · Cited by 240 · see citing works
Morecraft, R. J., Geula, C., & Mesulam, M. M. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540030045013 · Cited by 240 · see citing works
A unique representation of heat allodynia in the human brain
Lorenz, J., Cross, D. J., Minoshima, S., Morrow, T. J., Paulson, P. E., & Casey, K. L. (2002) · Neuron · doi:10.1016/s0896-6273(02)00767-5 · Cited by 233 · see citing works
Bernard, J., Bester, H., & Besson, J. (1996) · Progress in brain research · doi:10.1016/s0079-6123(08)61868-3 · Cited by 230 · see citing works
Bernard, J., Huang, G.-F., & Besson, J. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.68.2.551 · Cited by 230 · see citing works
George, M. S., Ketter, T. A., Parekh, P. I., Herscovitch, P., & Post, R. M. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00572-2 · Cited by 222 · see citing works
Hsieh, J., Tu, C., Chen, F.-P., Chen, M.-C., Yeh, T., Cheng, H.-C., Wu, Y., Liu, R.-S., & Ho, L. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)01952-8 · Cited by 222 · see citing works
Pain and Stroop interference tasks activate separate processing modules in anterior cingulate cortex
Derbyshire, S. W. G., Vogt, B. A., & Jones, A. K. P. (1998) · Experimental Brain Research · doi:10.1007/s002210050254 · Cited by 218 · see citing works
Self-citationAn fMRI study of cortical representation of mechanical allodynia in patients with neuropathic pain
Peyron, R., Schneider, F., Faillenot, I., Convers, P., Barral, F.-G., Garcı́a-Larrea, L., & Laurent, B. (2004) · Neurology · doi:10.1212/01.wnl.0000144177.61125.85 · Cited by 210 · see citing works
Responses of human cutaneous afferents to CO2 laser stimuli causing pain
Bromm, B., Jahnke, M. T., & Treede, R. (1984) · Experimental Brain Research · doi:10.1007/bf00240510 · Cited by 207 · see citing works
Cognitive modulation of pain-related brain responses depends on behavioral strategy
Seminowicz, D. A., Mikulis, D. J., & Davis, K. D. (2004) · Pain · doi:10.1016/j.pain.2004.07.027 · Cited by 203 · see citing works
Anterior cingulate cortex and the medial pain system,
Vogt, B. A., Sikes, R. W., & Vogt, L. J. (1993) · Neurobiology of Cingulate Cortex and Limbic Thalamus · doi:10.1007/978-1-4899-6704-6_11 · Cited by 196 · see citing works
Spatial orientation and the representation of space with parietal lobe lesions
Karnath, H. (1997) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1997.0127 · Cited by 196 · see citing works
Exploring the pain “neuromatrix”.
Derbyshire, S. W. G. (2000) · Current Review of Pain · doi:10.1007/s11916-000-0071-x · Cited by 182 · see citing works
Self-citationAdler, L. J., Gyulai, F. E., Diehl, D. J., Mintun, M. A., Winter, P. M., & Firestone, L. L. (1997) · Anesthesia & Analgesia · doi:10.1097/00000539-199701000-00023 · Cited by 174 · see citing works
Adler, L. J., Gyulai, F. E., Diehl, D. J., Mintun, M. A., Winter, P. M., & Firestone, L. L. (1997) · Anesthesia & Analgesia · doi:10.1213/00000539-199701000-00023 · Cited by 174 · see citing works
Right-lateralised central processing for pain of nitroglycer-induced cluster headache
Hsieh, J., Hannerz, J., & Ingvar, M. (1996) · Pain · doi:10.1016/0304-3959(96)03066-7 · Cited by 173 · see citing works
Lewis, M. E., Mishkin, M., Bragin, E. O., Brown, R. M., Pert, C. B., & Pert, A. (1981) · Science · doi:10.1126/science.6258227 · Cited by 166 · see citing works
Andersson, J., Lilja, A., Hartvig, P., Långström, B., Gordh, T., Handwerker, H. O., & Torebjörk, E. H. (1997) · Experimental Brain Research · doi:10.1007/s002210050215 · Cited by 159 · see citing works
Risk factors for persistent chronic widespread pain: a community-based study
McBeth, J. (2001) · British journal of rheumatology · doi:10.1093/rheumatology/40.1.95 · Cited by 154 · see citing works
Casey, K. L., Morrow, T., Lorenz, J., & Minoshima, S. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.2.951 · Cited by 145 · see citing works
(1972) · PubMed · Cited by 145 · see citing works
Persistent pain inhibits contralateral somatosensory cortical activity in humans
Apkarian, A. V., Stea, R. A., Manglos, S. H., Szeverenyi, N. M., King, R. B., & Thomas, F. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90088-o · Cited by 137 · see citing works
Left-hemisphere dominance in early nociceptive processing in the human parasylvian cortex
Schlereth, T., Baumgärtner, U., Magerl, W., Stoeter, P., & Treede, R. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00345-8 · Cited by 136 · see citing works
Jones, A. K. P., Kitchen, N. D., Watabe, H., Cunningham, V. J., Jones, T., Luthra, S. K., & Thomas, D. G. T. (1999) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-199907000-00011 · Cited by 100 · see citing works
Self-citationNeuronal correlates of gastric pain induced by fundus distension: a 3T‐fMRI study
Lu, C., Wu, Y., Yeh, T.-C., Chen, L., Chang, F. Y., Lee, S., Ho, L. ‐., & Hsieh, J. (2004) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2004.00562.x · Cited by 100 · see citing works
Maren, S., Poremba, A., & Michael, G. (1991) · Brain Research · doi:10.1016/0006-8993(91)90473-9 · Cited by 96 · see citing works
Cerebral Activation during Anal and Rectal Stimulation
Lotze, M., Wietek, B., Birbaumer, N., Ehrhardt, J., Grodd, W., & Enck, P. (2001) · NeuroImage · doi:10.1006/nimg.2001.0901 · Cited by 92 · see citing works
Bentley, D. E., Derbyshire, S. W. G., Youell, P. D., & Jones, A. K. P. (2003) · Pain · doi:10.1016/s0304-3959(02)00405-0 · Cited by 91 · see citing works
Self-citationVogt, B. A., Watanabe, H., Grootoonk, S., & Jones, A. K. P. (1995) · Human Brain Mapping · doi:10.1002/hbm.460030102 · Cited by 71 · see citing works
Self-citationBohus, B., Koolhaas, J. M., Luiten, P. G. M., Korte, S. M., Roozendaal, B., & Wiersma, A. (1996) · Progress in brain research · doi:10.1016/s0079-6123(08)61881-6 · Cited by 64 · see citing works
Subjective Ratings of Pain Correlate with Subcortical-Limbic Blood Flow: An fMRI Study
Schneider, F. W., Habel, U., Holthusen, H., Kessler, C., Posse, S., Müller‐Gärtner, H., & Arndt, J. O. (2001) · Neuropsychobiology · doi:10.1159/000054887 · Cited by 63 · see citing works
Cloning of a novel murine isoform of the glial cell line-derived neurotrophic factor receptor
Dey, B. K., Wong, Y. W., & Too, H. (1998) · Neuroreport · doi:10.1097/00001756-199801050-00008 · Cited by 61 · see citing works
Cytology of human dorsal midcingulate and supplementary motor cortices
Vogt, B. A., & Vogt, L. J. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2003.09.004 · Cited by 59 · see citing works
A framework for studying the neural basis of attention
Frith, C. (2001) · Neuropsychologia · doi:10.1016/s0028-3932(01)00124-5 · Cited by 48 · see citing works
Alteration in endogenous opioid systems due to chronic inflammatory pain conditions.
Spetea, M., Rydelius, G., Nylander, I., Ahmed, M., Bileviciute-Ljungar, I., Lundeberg, T., Svensson, S., & Kreicbergs, A. (2002) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01554-0 · Cited by 45 · see citing works
Bentley, D. E., Watson, A., Treede, R.-D., Barrett, G., Youell, P. D., Kulkarni, B., & Jones, A. K. P. (2004) · Clinical Neurophysiology · doi:10.1016/j.clinph.2004.03.010 · Cited by 44 · see citing works
Self-citationVisceral Afferent Pathways and Functional Brain Imaging
Derbyshire, S. W. G. (2003) · The Scientific World JOURNAL · doi:10.1100/tsw.2003.93 · Cited by 44 · see citing works
Self-citationUnmasking of an early laser evoked potential by a point localization task
Valeriani, M., Restuccia, D., Pera, D. L., Fiaschetti, L., Tonali, P. A., & Arendt‐Nielsen, L. (2000) · Clinical Neurophysiology · doi:10.1016/s1388-2457(00)00439-9 · Cited by 27 · see citing works
Increased activity of surviving locus ceruleus neurons in Alzheimer's disease
Moser (1999) · Pure Amsterdam UMC · doi:10.1002/1531-8249(199901)45:1
Worsley (1996) · doi:10.1002/(sici)1097-0193(1996)4:1
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Pain and emotion interactions in subregions of the cingulate gyrus
Vogt, B. A. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1704 · Cited by 1,810 · see citing works
Human empathy through the lens of social neuroscience.
Decety, J., & Lamm, C. (2006) · The Scientific World JOURNAL · doi:10.1100/tsw.2006.221 · Cited by 1,051 · see citing works
“This has been demonstrated in a positron emission tomography study in which participants were instructed to focus their attention either on the unpleasantness or the location of the noxious stimuli delivered on the participants’ hands[26], with the latter condition resulting in increased regional cerebral blood flow i…”
BackgroundEisenberger, N. I. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3231 · Cited by 1,016 · see citing works
Legrain, V., Iannetti, G. D., Plaghki, L., & Mouraux, A. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.10.005 · Cited by 854 · see citing works
Pain and emotion: a biopsychosocial review of recent research
Lumley, M. A., Cohen, J. L., Borszcz, G. S., Cano, A., Radcliffe, A. M., Porter, L. S., Schubiner, H., & Keefe, F. J. (2011) · Journal of Clinical Psychology · doi:10.1002/jclp.20816 · Cited by 836 · see citing works
Emotion and the prefrontal cortex: an integrative review
Dixon, M. L., Thiruchselvam, R., Todd, R., & Christoff, K. (2017) · Psychological Bulletin · doi:10.1037/bul0000096 · Cited by 745 · see citing works
Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response
Medford, N., & Critchley, H. D. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0265-x · Cited by 627 · see citing works
Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function
Seminowicz, D. A., Wideman, T. H., Naso, L., Hatami-Khoroushahi, Z., Fallatah, S., Ware, M. A., Jarzem, P., Bushnell, M. C., Shir, Y., Ouellet, J. A., et al. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5280-10.2011 · Cited by 622 · see citing works
Morrison, I., Löken, L. S., & Olausson, H. (2009) · Experimental Brain Research · doi:10.1007/s00221-009-2007-y · Cited by 549 · see citing works
Decety, J., & Moriguchi, Y. (2007) · BioPsychoSocial Medicine · doi:10.1186/1751-0759-1-22 · Cited by 497 · see citing works
The neural bases of social pain: Evidence for shared representations with physical pain
Eisenberger, N. I. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3182464dd1 · Cited by 492 · see citing works
Midcingulate cortex: Structure, connections, homologies, functions and diseases
Vogt, B. A. (2016) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2016.01.010 · Cited by 471 · see citing works
A biopsychosocial formulation of pain communication.
Hadjistavropoulos, T., Craig, K. D., Duck, S., Cano, A., Goubert, L., Jackson, P. L., Mogil, J. S., Rainville, P., Sullivan, M. J. L., Williams, A. C. D. C., et al. (2011) · Psychological Bulletin · doi:10.1037/a0023876 · Cited by 466 · see citing works
Lamm, C., Nusbaum, H. C., Meltzoff, A. N., & Decety, J. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001292 · Cited by 411 · see citing works
Burst Spinal Cord Stimulation for Limb and Back Pain
Ridder, D. D., Plazier, M., Kamerling, N., Menovsky, T., & Vanneste, S. (2013) · World Neurosurgery · doi:10.1016/j.wneu.2013.01.040 · Cited by 393 · see citing works
The Spinothalamic System Targets Motor and Sensory Areas in the Cerebral Cortex of Monkeys
Dum, R. P., Levinthal, D. J., & Strick, P. L. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3398-09.2009 · Cited by 377 · see citing works
Neural Origins of Human Sickness in Interoceptive Responses to Inflammation
Harrison, N. A., Brydon, L., Walker, C., Gray, M. A., Steptoe, A., Dolan, R. J., & Critchley, H. D. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.03.007 · Cited by 345 · see citing works
Kerr, C. E., Sacchet, M. D., Lazar, S. W., Moore, C. I., & Jones, S. R. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00012 · Cited by 320 · see citing works
Langguth, B., Landgrebe, M., Kleinjung, T., Sand, G. P., & Hajak, G. (2011) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.575178 · Cited by 321 · see citing works
The anatomy of pain and suffering in the brain and its clinical implications
Ridder, D. D., Adhia, D. B., & Vanneste, S. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.08.013 · Cited by 276 · see citing works
Cheng, Y., Yang, C., Lin, C., Lee, P., & Jean Decety, A. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.01.064 · Cited by 270 · see citing works
Relevance to self: A brief review and framework of neural systems underlying appraisal
Schmitz, T. W., & Johnson, S. C. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.12.003 · Cited by 271 · see citing works
Seminowicz, D. A., Laferriere, A. L., Millecamps, M., Yu, J. S. C., Coderre, T. J., & Bushnell, M. C. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.068 · Cited by 271 · see citing works
McCabe, C., Rolls, E. T., Bilderbeck, A., & McGlone, F. (2008) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsn005 · Cited by 262 · see citing works
Where is Cingulate Cortex? A Cross-Species View
van Heukelum, S., Mars, R. B., Guthrie, M., Buitelaar, J. K., Beckmann, C. F., Tiesinga, P. H. E., Vogt, B. A., Glennon, J. C., & Havenith, M. N. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.03.007 · Cited by 248 · see citing works
The sensory-discriminative and affective-motivational aspects of pain
Auvray, M., Myin, E., & Spence, C. J. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.07.008 · Cited by 237 · see citing works
The Bayesian brain: Phantom percepts resolve sensory uncertainty
Ridder, D. D., Vanneste, S., & Freeman, W. J. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.04.001 · Cited by 227 · see citing works
Brown, C. A., Seymour, B., Boyle, Y., El-Deredy, W., & Jones, A. K. P. (2008) · Pain · doi:10.1016/j.pain.2007.05.022 · Cited by 218 · see citing works
Self-citationArthritic pain is processed in brain areas concerned with emotions and fear
Kulkarni, B., Bentley, D. E., Elliott, R., Julyan, P. J., Boger, E. J., Watson, A., Boyle, Y., El‐Deredy, W., & Jones, A. K. P. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22460 · Cited by 214 · see citing works
Self-citationBurst and Tonic Spinal Cord Stimulation: Different and Common Brain Mechanisms
Ridder, D. D., & Vanneste, S. (2015) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12368 · Cited by 210 · see citing works
Brain imaging of pain: state of the art
Morton, D. L., Jones, A. K. P., & Sandhu, J. (2016) · Journal of Pain Research · doi:10.2147/jpr.s60433 · Cited by 211 · see citing works
Self-citationBrain imaging approaches to the study of functional GI disorders: A Rome Working Team Report
Mayer, E. A., Aziz, Q., Coen, S., Kern, M., Labus, J. S., Lane, R., Kuo, B., Naliboff, B., & Tracey, I. (2009) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2009.01304.x · Cited by 204 · see citing works
Psychological pain: A review of evidence
Mee, S., Bunney, B. G., Reist, C., Potkin, S. G., & Bunney, W. E. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.03.003 · Cited by 188 · see citing works
Watson, A., El‐Deredy, W., Iannetti, G. D., Lloyd, D. M., Tracey, I., Vogt, B. A., Nadeau, V. J., & Jones, A. K. P. (2009) · Pain · doi:10.1016/j.pain.2009.04.003 · Cited by 182 · see citing works
Self-citationDoes It Look Painful or Disgusting? Ask Your Parietal and Cingulate Cortex
Benuzzi, F., Lui, F., Duzzi, D., Nichelli, P., & Porro, C. A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4012-07.2008 · Cited by 178 · see citing works
Pain sensation evoked by observing injury in others
Osborn, J., & Derbyshire, S. W. G. (2009) · Pain · doi:10.1016/j.pain.2009.11.007 · Cited by 169 · see citing works
Self-citationPain and the Triple Network Model
Ridder, D. D., Vanneste, S., Smith, M. L., & Adhia, D. B. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.757241 · Cited by 174 · see citing works
ALE meta‐analysis reveals dissociable networks for affective and discriminative aspects of touch
Morrison, I. (2016) · Human Brain Mapping · doi:10.1002/hbm.23103 · Cited by 164 · see citing works
Pain and post traumatic stress disorder - review of clinical and experimental evidence
Moeller-Bertram, T., Keltner, J., & Strigo, I. A. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.04.028 · Cited by 163 · see citing works
Atlas, L. Y., & Wager, T. D. (2014) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-662-44519-8_3 · Cited by 162 · see citing works
Schwedt, T. J., Chong, C. D., Chiang, C., Baxter, L. C., Schlaggar, B. L., & Dodick, D. W. (2014) · Cephalalgia · doi:10.1177/0333102414526069 · Cited by 160 · see citing works
Cascio, C. J., Moana‐Filho, E. J., Guest, S., Nebel, M. B., Weisner, J., Baranek, G. T., & Essick, G. K. (2012) · Autism Research · doi:10.1002/aur.1224 · Cited by 154 · see citing works
Tiede, W., Magerl, W., Baumgärtner, U., Durrer, B., Ehlert, U., & Treede, R.-D. (2010) · Pain · doi:10.1016/j.pain.2009.08.029 · Cited by 153 · see citing works
The Sight of Others' Pain Modulates Motor Processing in Human Cingulate Cortex
Morrison, I., Peelen, M. V., & Downing, P. E. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhl129 · Cited by 147 · see citing works
Parallel Processing of Nociceptive A-δ Inputs in SII and Midcingulate Cortex in Humans
Frot, M., Mauguı̀ere, F., Magnin, M., & Garcı́a-Larrea, L. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2934-07.2008 · Cited by 148 · see citing works
First-in-human prediction of chronic pain state using intracranial neural biomarkers
Shirvalkar, P. R., Prosky, J., Chin, G., Ahmadipour, P., Sani, O. G., Desai, M., Schmitgen, A., Dawes, H. E., Shanechi, M. M., Starr, P. A., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01338-z · Cited by 146 · see citing works
White matter brain and trigeminal nerve abnormalities in temporomandibular disorder
Moayedi, M., Weissman-Fogel, I., Salomons, T. V., Crawley, A. P., Goldberg, M. B., Freeman, B. V., Tenenbaum, H. C., & Davis, K. D. (2012) · Pain · doi:10.1016/j.pain.2012.04.003 · Cited by 144 · see citing works
Ng, S. K., Urquhart, D. M., Fitzgerald, P. B., Cicuttini, F., Hussain, S. M., & Fitzgibbon, B. M. (2017) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000534 · Cited by 145 · see citing works
Joosten, E. A. J., & Franken, G. (2020) · Pain · doi:10.1097/j.pain.0000000000001854 · Cited by 135 · see citing works
Brain Mechanisms Supporting Discrimination of Sensory Features of Pain: A New Model
Oshiro, Y., Quevedo, A. S., McHaffie, J. G., Kraft, R. A., & Coghill, R. C. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5538-08.2009 · Cited by 133 · see citing works
Amygdala activity contributes to the dissociative effect of cannabis on pain perception
Lee, M., Ploner, M., Wiech, K., Bingel, U., Wanigasekera, V., Brooks, J. C. W., Menon, D. K., & Tracey, I. (2012) · Pain · doi:10.1016/j.pain.2012.09.017 · Cited by 133 · see citing works
Torta, D. M. E., Legrain, V., Mouraux, A., & Valentini, E. (2017) · Cortex · doi:10.1016/j.cortex.2017.01.010 · Cited by 127 · see citing works
Brain activity associated with the electrodermal reactivity to acute heat pain
Dubé, A.-A., Duquette, M., Roy, M., Leporé, F., Duncan, G. H., & Rainville, P. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.10.024 · Cited by 121 · see citing works
The Recurrent Pain and Sexual Sequelae of Provoked Vestibulodynia: A Perpetuating Cycle
Basson, R. J. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02803.x · Cited by 115 · see citing works
Modulation of pain perception by transcranial magnetic stimulation of left prefrontal cortex
Brighina, F., De Tommaso, M., Giglia, F., Scalia, S., Cosentino, G., Puma, A., Panetta, M., Giglia, G., & Fierro, B. (2011) · The Journal of Headache and Pain · doi:10.1007/s10194-011-0322-8 · Cited by 115 · see citing works
Gender Differences in Placebo Analgesia: Event-Related Potentials and Emotional Modulation
Aslaksen, P. M., Bystad, M. K., Vambheim, S. M., & Flaten, M. A. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3182080d73 · Cited by 111 · see citing works
Breaking down the Barriers: fMRI Applications in Pain, Analgesia and Analgesics
Borsook, D., & Becerra, L. R. (2006) · Molecular Pain · doi:10.1186/1744-8069-2-30 · Cited by 108 · see citing works
A supramodal representation of the body surface
Mancini, F., Longo, M. R., Iannetti, G. D., & Haggard, P. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.12.040 · Cited by 105 · see citing works
Mechanism of Action in Burst Spinal Cord Stimulation: Review and Recent Advances
Chakravarthy, K. V., Fishman, M. A., Zuidema, X., Hunter, C., & Levy, R. M. (2019) · Pain Medicine · doi:10.1093/pm/pnz073 · Cited by 99 · see citing works
Becerra, L. R., Navratilova, E., Porreca, F., & Borsook, D. (2013) · Journal of Neurophysiology · doi:10.1152/jn.00284.2013 · Cited by 99 · see citing works
Brown, C. A., & Jones, A. K. P. (2012) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e31824c5d9f · Cited by 98 · see citing works
Self-citationBumgarner, J. R., Walker, W. H., & Nelson, R. J. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.08.004 · Cited by 96 · see citing works
Brain dynamics for perception of tactile allodynia (touch-induced pain) in postherpetic neuralgia
Geha, P., Baliki, M. N., Wang, X., Harden, R. N., Paice, J. A., & Apkarian, A. V. (2008) · Pain · doi:10.1016/j.pain.2008.02.021 · Cited by 93 · see citing works
What are C-tactile afferents and how do they relate to “affective touch”?
Schirmer, A., Croy, I., & Ackerley, R. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105236 · Cited by 97 · see citing works
Neurofeedback and Neuromodulation Techniques and Applications
Coben, R., & Evans, J. R. (2011) · Elsevier eBooks · doi:10.1016/c2009-0-64101-5 · Cited by 91 · see citing works
Auditory cortex stimulation for tinnitus
Ridder, D. A., Mulder, G. D., Verstraeten, E., Seidman, M. D., Elisevich, K. V., Sunaert, S. G., Kovacs, S., der Kelen, K. V., de Heyning, P. V., & Møller, A. R. (2007) · Springer eBooks · doi:10.1007/978-3-211-33081-4_52 · Cited by 91 · see citing works
Negative Mood Affects Brain Processing of Visceral Sensation
Coen, S. J., Yágüez, L., Aziz, Q., Mitterschiffthaler, M. T., Brammer, M. J., Williams, S., & Gregory, L. J. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.02.052 · Cited by 90 · see citing works
Sensitivity to pain expectations: A Bayesian model of individual differences
Hoskin, R., Berzuini, C., Acosta-Kane, D., El-Deredy, W., Guo, H., & Talmi, D. (2019) · Cognition · doi:10.1016/j.cognition.2018.08.022 · Cited by 87 · see citing works
The Role of the Brain's Endocannabinoid System in Pain and Its Modulation by Stress
Corcoran, L., Roche, M., & Finn, D. P. (2015) · International review of neurobiology · doi:10.1016/bs.irn.2015.10.003 · Cited by 86 · see citing works
The Role of the Skin in Interoception: A Neglected Organ?
Crucianelli, L., & Ehrsson, H. H. (2022) · Perspectives on Psychological Science · doi:10.1177/17456916221094509 · Cited by 86 · see citing works
Functional brain imaging of gastrointestinal sensation in health and disease
Oudenhove, L. V. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i25.3438 · Cited by 85 · see citing works
Affective neuroscience of self‐generated thought
Fox, K. C. R., Andrews‐Hanna, J. R., Mills, C., Dixon, M. L., Markovic, J., Thompson, E. T., & Kalina Christoff, A. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13740 · Cited by 92 · see citing works
Touch or pain? Spatio-temporal patterns of cortical fMRI activity following brief mechanical stimuli
Lui, F., Duzzi, D., Corradini, M., Serafini, M., Baraldi, P., & Porro, C. A. (2008) · Pain · doi:10.1016/j.pain.2008.01.010 · Cited by 86 · see citing works
Wright, H., Li, X., Fallon, N. B., Crookall, R., Giesbrecht, T., Thomas, A. K., Halford, J. C. G., Harrold, J. A., & Stančák, A. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13182 · Cited by 82 · see citing works
Nociception and autonomic nervous system
Cortelli, P., Giannini, G., Favoni, V., Cevoli, S., & Pierangeli, G. (2013) · Neurological Sciences · doi:10.1007/s10072-013-1391-z · Cited by 81 · see citing works
Andrade, S. M., Aranha, R. E. L. D. B., de Oliveira, E. A., de Mendonça, C. T. P. L., Martins, W. K. N., Alves, N. T., & Fernández‐Calvo, B. (2017) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2017.05.007 · Cited by 81 · see citing works
Vaseghi, B., Zoghi, M., & Jaberzadeh, S. J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0118340 · Cited by 80 · see citing works
Regional brain responses associated with drinking water during thirst and after its satiation
Saker, P., Farrell, M. J., Adib, F. R. M., Egan, G. F., McKinley, M. J., & Denton, D. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1403382111 · Cited by 79 · see citing works
rTMS for the treatment of tinnitus: The role of neuronavigation for coil positioning
Langguth, B., Kleinjung, T., Landgrebe, M., Ridder, D. D., & Hajak, G. (2009) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2009.03.001 · Cited by 79 · see citing works
Individual variability in brain representations of pain
Kohoutová, L., Atlas, L. Y., Büchel, C., Buhle, J. T., Geuter, S., Jepma, M., Koban, L., Krishnan, A., Lee, D. H., Lee, S., et al. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01081-x · Cited by 77 · see citing works
Hypnosis and Surgery: Past, Present, and Future
Wobst, A. H. K. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000260616.49050.6d · Cited by 81 · see citing works
Yang, J., Shih, H.-C., & Shyu, B. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00623.2006 · Cited by 77 · see citing works
Stankewitz, A., Schulz, E., & May, A. (2012) · Cephalalgia · doi:10.1177/0333102412470215 · Cited by 75 · see citing works
Facets and mechanisms of adaptive pain behavior: predictive regulation and action
Morrison, I., Perini, I., & Dunham, J. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00755 · Cited by 74 · see citing works
Eck, J., Richter, M., Straube, T., Miltner, W. H. R., & Weiß, T. (2011) · Pain · doi:10.1016/j.pain.2011.01.026 · Cited by 72 · see citing works
Crossmodal shaping of pain: a multisensory approach to nociception
Senkowski, D., Höfle, M., & Engel, A. K. (2014) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2014.03.005 · Cited by 73 · see citing works
Painful tonic heat stimulation induces GABA accumulation in the prefrontal cortex in man
Kupers, R. C., Danielsen, E. R., Kehlet, H., Christensen, R. H., & Thomsen, C. E. (2009) · Pain · doi:10.1016/j.pain.2008.12.008 · Cited by 71 · see citing works
Wang, A. L., Mouraux, A., Liang, M., & Iannetti, G. D. (2010) · Journal of Neurophysiology · doi:10.1152/jn.01088.2009 · Cited by 71 · see citing works
Submodalities of emotion in the context of cingulate subregions
Vogt, B. A. (2014) · Cortex · doi:10.1016/j.cortex.2014.04.002 · Cited by 71 · see citing works
NIRS measures in pain and analgesia: Fundamentals, features, and function
Karunakaran, K. D., Peng, K., Berry, D., Green, S. A., Labadie, R. F., Kussman, B. D., & Borsook, D. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.10.023 · Cited by 69 · see citing works
Chakravarthy, K. V., Malayil, R., Kirketeig, T., & Deer, T. R. (2019) · Pain Medicine · doi:10.1093/pm/pnz046 · Cited by 65 · see citing works
Central nervous system dysregulation extends beyond the pain-matrix network in cluster headache
Rocca, M. A., Valsasina, P., Absinta, M., Colombo, B., Barcella, V., Falini, A., Comi, G., & Filippi, M. (2010) · Cephalalgia · doi:10.1177/0333102410365164 · Cited by 64 · see citing works
Pilitsis, J. G., Fahey, M. E., Custozzo, A. J., Chakravarthy, K. V., & Capobianco, R. A. (2020) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.13212 · Cited by 64 · see citing works
A role for midcingulate cortex in the interruptive effects of pain anticipation on attention
Brown, C. A., & Jones, A. K. P. (2008) · Clinical Neurophysiology · doi:10.1016/j.clinph.2008.06.014 · Cited by 61 · see citing works
Self-citationA Systematic Evaluation of Burst Spinal Cord Stimulation for Chronic Back and Limb Pain
Hou, S., Kemp, K., & Grabois, M. (2016) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12440 · Cited by 59 · see citing works
Pacreu, S., Candil, J. F., Moltó, L., Carazo, J., & Fernández-Galinski, S. (2012) · Acta Anaesthesiologica Scandinavica · doi:10.1111/j.1399-6576.2012.02743.x · Cited by 59 · see citing works
Monconduit, L., López-Ávila, A., Molat, J.-L., Chalus, M., & Villanueva, L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1293-06.2006 · Cited by 59 · see citing works
New Insights in Trigeminal Anatomy: A Double Orofacial Tract for Nociceptive Input
Henssen, D. J. H. A., Kurt, E., Kozicz, T., van Dongen, R. T. M., Bartels, R., & van Walsum, A. V. C. (2016) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2016.00053 · Cited by 59 · see citing works
Distribution and properties of visceral nociceptive neurons in rabbit cingulate cortex
Sikes, R. W., Vogt, L. J., & Vogt, B. A. (2007) · Pain · doi:10.1016/j.pain.2007.09.024 · Cited by 59 · see citing works
Event-based control of autonomic and emotional states by the anterior cingulate cortex
Seamans, J. K., & Floresco, S. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.12.026 · Cited by 58 · see citing works
- Authors
- Kulkarni, B., Bentley, D. E., Elliott, R., Youell, P., Watson, A., Derbyshire, S. W. G., Frackowiak, R. S. J., Friston, K. J., & Jones, A. K. P.
- Affiliations
- Salford Royal Hospital (GB)
- University of Manchester (GB)
- University of Pittsburgh (US)
- National Hospital for Neurology and Neurosurgery (GB)
- Corresponding author
- Kulkarni, B.
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2005-06
- Volume
- 21
- Issue
- 11
- Pages
- 3133-3142
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W2016341768
- Cited by
- 337
- References
- 90
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 10 · 2023: 18 · 2022: 27 · 2021: 13 · 2020: 22 · 2019: 20 · 2018: 14 · 2017: 24 · 2016: 17 · 2015: 16 · 2014: 16 · 2013: 10 · 2012: 15
- FWCI
- 8.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Funders
- Wellcome Trust
- Topics
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- pain localization, pain unpleasantness, attentional modulation of pain, nociceptive processing, primary somatosensory cortex, inferior parietal cortex, orbitofrontal cortex, amygdala, hypothalamus, posterior insula
- MeSH terms
- Adult, Afferent Pathways, Attention, Brain, Brain Mapping, Emotions, Humans, Functional Laterality, Limbic System, Male, Nerve Fibers, Myelinated, Neurosecretory Systems, Nociceptors, Pain, Physical Stimulation, Somatosensory Cortex, Nerve Fibers, Unmyelinated, Positron-Emission Tomography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
