RNA-Guided Human Genome Engineering via Cas9

Cited by (1,104)

Items 101–200 of 1,104

1. Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease
   Vladimir Nekrasov, Brian J. Staskawicz, Detlef Weigel, Jonathan D. G. Jones, Sophien Kamoun · 2013 · Nature Biotechnology
2. Overcoming cellular barriers for RNA therapeutics
   Dowdy, Steven F · 2017 · Nature Biotechnology
3. Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
   Maruyama, Takeshi, Dougan, Stephanie K, Truttmann, Matthias C, Bilate, Angelina M, Ingram, Jessica R, Ploegh, Hidde L · 2015 · Nature Biotechnology
4. CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
   Liang, Puping, Xu, Yanwen, Zhang, Xiya, Ding, Chenhui, Huang, Rui, Zhang, Zhen, Lv, Jie, Xie, Xiaowei, Chen, Yuxi, Li, Yujing et al. · 2015 · Protein & Cell
5. Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids
   Matano, Mami, Date, Shoichi, Shimokawa, Mariko, Takano, Ai, Fujii, Masayuki, Ohta, Yuki, Watanabe, Toshiaki, Kanai, Takanori, Sato, Toshiro · 2015 · Nature Medicine
6. The promise and challenge of therapeutic genome editing
   Doudna, Jennifer A. · 2020 · Nature
7. Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
   Hendel, Ayal, Bak, Rasmus O, Clark, Joseph T, Kennedy, Andrew B, Ryan, Daniel E, Roy, Subhadeep, Steinfeld, Israel, Lunstad, Benjamin D, Kaiser, Robert J, Wilkens, Alec B et al. · 2015 · Nature Biotechnology
8. Roles, Functions, and Mechanisms of Long Non-Coding RNAs in Cancer
   Yiwen Fang, Melissa J. Fullwood · 2016 · Genomics Proteomics & Bioinformatics
9. CCTop: An intuitive, flexible and reliable CRISPR/Cas9 target prediction tool
   Stemmer, Manuel, Thumberger, Thomas, del Sol Keyer, Maria, Wittbrodt, Joachim, Mateo, Juan L. · 2015 · PLoS ONE
10. CRISPR technology: A decade of genome editing is only the beginning
    Joy Y. Wang, Jennifer A. Doudna · 2023 · Science
11. Sequential cancer mutations in cultured human intestinal stem cells
    Drost, Jarno, van Jaarsveld, Richard H., Ponsioen, Bas, Zimberlin, Cheryl, van Boxtel, Ruben, Buijs, Arjan, Sachs, Norman, Overmeer, René M., Offerhaus, G. Johan, Begthel, Harry et al. · 2015 · Nature
12. Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
    Koike-Yusa, Hiroko, Li, Yilong, Tan, E-Pien, Velasco-Herrera, Martin Del Castillo, Yusa, Kosuke · 2014 · Nature Biotechnology
13. Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
    Zhi-Ping Wang, Hui-Li Xing, Dong Li, Hai-Yan Zhang, Chun-Yan Han, Xue-Chen Wang, Qi-Jun Chen · 2015 · Genome biology
14. In vivo gene editing in dystrophic mouse muscle and muscle stem cells
    Tabebordbar, Mohammadsharif, Zhu, Kexian, Cheng, Jason K. W., Chew, Wei Leong, Widrick, Jeffrey J., Yan, Winston X., Maesner, Claire, Wu, Elizabeth Y., Xiao, Ru, Ran, F. Ann et al. · 2016 · Science
15. Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila
    Port, Fillip, Chen, Hui-Min, Lee, Tzumin, Bullock, Simon L. · 2014 · Proceedings of the National Academy of Sciences
16. CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
    Alexis C. Komor, Ahmed H. Badran, David R. Liu · 2016 · Cell
17. Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos
    Niu, Yuyu, Shen, Bin, Cui, Yiqiang, Chen, Yongchang, Wang, Jianying, Wang, Lei, Kang, Yu, Zhao, Xiaoyang, Si, Wei, Li, Wei et al. · 2014 · Cell
18. ARGOS 8 variants generated by CRISPR ‐Cas9 improve maize grain yield under field drought stress conditions
    Shi, Jinrui, Gao, Huirong, Wang, Hongyu, Lafitte, H. Renee, Archibald, Rayeann L., Yang, Meizhu, Hakimi, Salim M., Mo, Hua, Habben, Jeffrey E. · 2017 · Plant Biotechnology Journal
19. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
    Thakore, Pratiksha I, D'Ippolito, Anthony M, Song, Lingyun, Safi, Alexias, Shivakumar, Nishkala K, Kabadi, Ami M, Reddy, Timothy E, Crawford, Gregory E, Gersbach, Charles A · 2015 · Nature Methods
20. Applications of CRISPR technologies in research and beyond
    Barrangou, Rodolphe, Doudna, Jennifer A · 2016 · Nature Biotechnology
21. Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease
    Scott J. Gratz, Alexander M Cummings, Jennifer N Nguyen, Danielle C. Hamm, Laura K Donohue, Melissa M. Harrison, Jill Wildonger, Kate M. O’Connor-Giles · 2013 · Genetics
22. Digenome-seq: Genome-wide profiling of CRISPR-cas9 off-target effects in human cells
    Kim, Daesik, Bae, Sangsu, Park, Jeongbin, Kim, Eunji, Kim, Seokjoong, Yu, Hye Ryeong, Hwang, Jinha, Kim, Jong-Il, Kim, Jin-Soo · 2015 · Nature Methods
23. The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.
    Kang, Chanhee, Xu, Qikai, Martin, Timothy D., Li, Mamie Z., Demaria, Marco, Aron, Liviu, Lu, Tao, Yankner, Bruce A., Campisi, Judith, Elledge, Stephen J. · 2015 · Science
24. p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
    Ihry, Robert J., Worringer, Kathleen A., Salick, Max R., Frias, Elizabeth, Ho, Daniel, Theriault, Kraig, Kommineni, Sravya, Chen, Julie, Sondey, Marie, Ye, Chaoyang et al. · 2018 · Nature Medicine
25. Correction of a pathogenic gene mutation in human embryos
    Ma, Hong, Marti-Gutierrez, Nuria, Park, Sang-Wook, Wu, Jun, Lee, Yeonmi, Suzuki, Keiichiro, Koski, Amy, Ji, Dongmei, Hayama, Tomonari, Ahmed, Riffat et al. · 2017 · Nature
26. CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function
    Guo, Ya, Xu, Quan, Canzio, Daniele, Shou, Jia, Li, Jinhuan, Gorkin, David U., Jung, Inkyung, Wu, Haiyang, Zhai, Yanan, Tang, Yuanxiao et al. · 2015 · Cell
27. Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination
    Daniel J. Dickinson, Jordan D. Ward, David J. Reiner, Bob Goldstein · 2013 · Nature Methods
28. Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
    Tsai, Shengdar Q, Wyvekens, Nicolas, Khayter, Cyd, Foden, Jennifer A, Thapar, Vishal, Reyon, Deepak, Goodwin, Mathew J, Aryee, Martin J, Joung, J Keith · 2014 · Nature Biotechnology
29. Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
    Paquet, Dominik, Kwart, Dylan, Chen, Antonia, Sproul, Andrew, Jacob, Samson, Teo, Shaun, Olsen, Kimberly Moore, Gregg, Andrew, Noggle, Scott, Tessier-Lavigne, Marc · 2016 · Nature
30. Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
    Yin, Hao, Xue, Wen, Chen, Sidi, Bogorad, Roman L, Benedetti, Eric, Grompe, Markus, Koteliansky, Victor, Sharp, Phillip A, Jacks, Tyler, Anderson, Daniel G · 2014 · Nature Biotechnology
31. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
    Wu, Xuebing, Scott, David A, Kriz, Andrea J, Chiu, Anthony C, Hsu, Patrick D, Dadon, Daniel B, Cheng, Albert W, Trevino, Alexandro E, Konermann, Silvana, Chen, Sidi et al. · 2014 · Nature Biotechnology
32. Multiplex genome editing to generate universal CAR T cells resistant to PD1 inhibition
    Ren, Jiangtao, Liu, Xiaojun, Fang, Chongyun, Jiang, Shuguang, June, Carl H., Zhao, Yangbing · 2017 · Clinical Cancer Research
33. Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in Drosophila
    Scott J. Gratz, Fiona P. Ukken, Clifford Dustin Rubinstein, Gene H Thiede, Laura K Donohue, Alexander M Cummings, Kate M. O’Connor-Giles · 2014 · Genetics
34. Repair of Strand Breaks by Homologous Recombination
    Maria Jasin, Rodney J. Rothstein · 2013 · Cold Spring Harbor Perspectives in Biology
35. CRISPR/Cas Systems towards Next-Generation Biosensing
    Yi Li, Shiyuan Li, Jin Wang, Guozhen Liu · 2019 · Trends in biotechnology
36. Gene therapy clinical trials worldwide to 2017: An update
    Ginn, Samantha L., Amaya, Anais K., Alexander, Ian E., Edelstein, Michael, Abedi, Mohammad R. · 2018 · The Journal of Gene Medicine
37. Heritable genome editing in C. elegans via a CRISPR-Cas9 system
    Friedland, Ari E, Tzur, Yonatan B, Esvelt, Kevin M, Colaiácovo, Monica P, Church, George M, Calarco, John A · 2013 · Nature Methods
38. Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs
    James A. Gagnon, Eivind Valen, Summer B. Thyme, Peng Huang, Laila Ahkmetova, Andrea Pauli, Tessa G. Montague, Steve Zimmerman, Constance Richter, Alexander F. Schier · 2014 · PLoS ONE
39. Engineered biomaterials for in situ tissue regeneration
    Akhilesh K. Gaharwar, Irtisha Singh, Ali Khademhosseini · 2020 · Nature Reviews Materials
40. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
    Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Sanjana, Neville E., Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P. et al. · 2015 · Nature
41. E-CRISP: fast CRISPR target site identification
    Florian Heigwer, Gráinne Kerr, Michael Boutros · 2014 · Nature Methods
42. Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System
    Andrew Roger Bassett, Charlotte Tibbit, Chris P. Ponting, Ji‐Long Liu · 2013 · Cell Reports
43. Concerning RNA-guided gene drives for the alteration of wild populations
    Kevin M. Esvelt, Andrea L. Smidler, Flaminia Catteruccia, George McDonald Church · 2014 · eLife
44. Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
    Yin, Hao, Song, Chun-Qing, Dorkin, Joseph R, Zhu, Lihua J, Li, Yingxiang, Wu, Qiongqiong, Park, Angela, Yang, Junghoon, Suresh, Sneha, Bizhanova, Aizhan et al. · 2016 · Nature Biotechnology
45. Applications of CRISPR–Cas in agriculture and plant biotechnology
    Zhu, Haocheng, Li, Chao, Gao, Caixia · 2020 · Nature Reviews Molecular Cell Biology
46. Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins
    Prakash, Rohit, Zhang, Yu, Feng, Weiran, Jasin, Maria · 2015 · Cold Spring Harbor Perspectives in Biology
47. Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
    Chen, Sidi, Sanjana, Neville E., Zheng, Kaijie, Shalem, Ophir, Lee, Kyungheon, Shi, Xi, Scott, David A., Song, Jun, Pan, Jen Q., Weissleder, Ralph et al. · 2015 · Cell
48. Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
    Wang, Gang, McCain, Megan L, Yang, Luhan, He, Aibin, Pasqualini, Francesco Silvio, Agarwal, Ashutosh, Yuan, Hongyan, Jiang, Dawei, Zhang, Donghui, Zangi, Lior et al. · 2014 · Nature Medicine
49. Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
    Guilinger, John P, Thompson, David B, Liu, David R · 2014 · Nature Biotechnology
50. Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos
    Nannan Chang, Changhong Sun, Lu Gao, Dan Zhu, Xiufei Xu, Xiaojun Zhu, Jing‐Wei Xiong, Jianzhong Xi · 2013 · Cell Research
51. Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation
    Dominguez, Antonia A., Lim, Wendell A., Qi, Lei S. · 2016 · Nature Reviews Molecular Cell Biology
52. CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity
    Barrangou, Rodolphe, Marraffini, Luciano A. · 2014 · Molecular Cell
53. RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System
    Kabin Xie, Yinong Yang · 2013 · Molecular Plant
54. CRISPR-P: A Web Tool for Synthetic Single-Guide RNA Design of CRISPR-System in Plants
    Lei Yang, Li Lü, Haiyang Liu, Sen Li, Xing Feng, Ling‐Ling Chen · 2014 · Molecular Plant
55. CIRCLE-Seq: A highly sensitive in vitro screen for genome-wide CRISPR-cas9 nuclease off-targets
    Tsai, Shengdar Q, Nguyen, Nhu T, Malagon-Lopez, Jose, Topkar, Ved V, Aryee, Martin J, Joung, J Keith · 2017 · Nature Methods
56. CRISPR/Cas9 therapeutics: progress and prospects
    Tianxiang Li, Yanyan Yang, Hongzhao Qi, Weigang Cui, Lin Zhang, Xiuxiu Fu, Xiangqin He, Meixin Liu, Peifeng Li, Tao Yu · 2023 · Signal Transduction and Targeted Therapy
57. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
    Benjamin Freedman, Craig R. Brooks, Albert Q. Lam, Hongxia Fu, Ryuji Morizane, Vishesh Agrawal, Abdelaziz F. Saad, Michelle K. Li, Michael R. Hughes, Ryan Vander Werff et al. · 2015 · Nature Communications
58. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
    Esvelt, Kevin M, Mali, Prashant, Braff, Jonathan L, Moosburner, Mark, Yaung, Stephanie J, Church, George M · 2013 · Nature Methods
59. Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
    Kuscu, Cem, Arslan, Sevki, Singh, Ritambhara, Thorpe, Jeremy, Adli, Mazhar · 2014 · Nature Biotechnology
60. Human iPSC-based modeling of late-onset disease via progerin-induced aging
    Miller, Justine D., Ganat, Yosif M., Kishinevsky, Sarah, Bowman, Robert L., Liu, Becky, Tu, Edmund Y., Mandal, Pankaj K., Vera, Elsa, Shim, Jae-won, Kriks, Sonja et al. · 2013 · Cell stem cell
61. CRISPR-mediated direct mutation of cancer genes in the mouse liver
    Xue, Wen, Chen, Sidi, Yin, Hao, Tammela, Tuomas, Papagiannakopoulos, Thales, Joshi, Nikhil S., Cai, Wenxin, Yang, Gillian, Bronson, Roderick, Crowley, Denise G. et al. · 2014 · Nature
62. Genome editing in rice and wheat using the CRISPR/Cas system
    Qiwei Shan, Yanpeng Wang, Jun Li, Caixia Gao · 2014 · Nature Protocols
63. Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
    Shen, Bin, Zhang, Wensheng, Zhang, Jun, Zhou, Jiankui, Wang, Jianying, Chen, Li, Wang, Lu, Hodgkins, Alex, Iyer, Vivek, Huang, Xingxu et al. · 2014 · Nature Methods
64. Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
    Takashi Yamano, Hiroshi Nishimasu, Bernd Zetsche, Hisato Hirano, Ian M. Slaymaker, Yinqing Li, Iana Fedorova, Takanori Nakane, Kira S. Makarova, Eugene V. Koonin et al. · 2016 · Cell
65. Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
    Albert W. Cheng, Haoyi Wang, Hui Yang, Linyu Shi, Yarden Katz A, Thorold W. Theunissen, Sudharshan Rangarajan, Chikdu Shivalila, Daniel Benjamin Dadon, Rudolf Jaenisch · 2013 · Cell Research
66. A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
    Tzelepis, Konstantinos, Koike-Yusa, Hiroko, De Braekeleer, Etienne, Li, Yilong, Metzakopian, Emmanouil, Dovey, Oliver M., Mupo, Annalisa, Grinkevich, Vera, Li, Meng, Mazan, Milena et al. · 2016 · Cell Reports
67. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
    Dowdle, William E., Nyfeler, Beat, Nagel, Jane, Elling, Robert A., Liu, Shanming, Triantafellow, Ellen, Menon, Suchithra, Wang, Zuncai, Honda, Ayako, Pardee, Gwynn et al. · 2014 · Nature Cell Biology
68. RETRACTED ARTICLE: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins
    Martinez, Jennifer, Malireddi, R. K. Subbarao, Lu, Qun, Cunha, Larissa Dias, Pelletier, Stephane, Gingras, Sebastien, Orchard, Robert, Guan, Jun-Lin, Tan, Haiyan, Peng, Junmin et al. · 2015 · Nature Cell Biology · Retracted
69. Differential regulation of mTORC1 by leucine and glutamine
    Jewell, Jenna L., Kim, Young Chul, Russell, Ryan C., Yu, Fa-Xing, Park, Hyun Woo, Plouffe, Steven W., Tagliabracci, Vincent S., Guan, Kun-Liang · 2015 · Science
70. Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains
    Junwei Shi, Eric Wang, Joseph P. Milazzo, Zihua Wang, Justin B. Kinney, Christopher R. Vakoc · 2015 · Nature Biotechnology
71. Targeted Mutagenesis, Precise Gene Editing, and Site-Specific Gene Insertion in Maize Using Cas9 and Guide RNA
    Sergei K. Svitashev, Joshua K. Young, Christine Schwartz, Huirong Gao, S. Carl Falco, A. Mark Cigan · 2015 · PLANT PHYSIOLOGY
72. Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair
    Lee, Kunwoo, Conboy, Michael, Park, Hyo Min, Jiang, Fuguo, Kim, Hyun Jin, Dewitt, Mark A., Mackley, Vanessa A., Chang, Kevin, Rao, Anirudh, Skinner, Colin et al. · 2017 · Nature Biomedical Engineering
73. Genome-editing Technologies for Gene and Cell Therapy
    Morgan L. Maeder, Charles A. Gersbach · 2016 · Molecular Therapy
74. Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions
    Peilin Lu, Dongxue Ruan, Meiqi Huang, Mi Tian, Kangshun Zhu, Ziqi Gan, Zecong Xiao · 2024 · Signal Transduction and Targeted Therapy
75. A prudent path forward for genomic engineering and germline gene modification
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76. Rapid and highly efficient mammalian cell engineering via Cas9 protein transfection
    Liang, Xiquan, Potter, Jason, Kumar, Shantanu, Zou, Yanfei, Quintanilla, Rene, Sridharan, Mahalakshmi, Carte, Jason, Chen, Wen, Roark, Natasha, Ranganathan, Sridhar et al. · 2015 · Journal of Biotechnology
77. High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells
    Zhou, Yuexin, Zhu, Shiyou, Cai, Changzu, Yuan, Pengfei, Li, Chunmei, Huang, Yanyi, Wei, Wensheng · 2014 · Nature
78. Both CRISPR / C as‐based nucleases and nickases can be used efficiently for genome engineering in A rabidopsis thaliana
    Friedrich Fauser, Simon Schiml, Holger Puchta · 2014 · The Plant Journal
79. Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells
    Kim, Daesik, Kim, Jungeun, Hur, Junho K, Been, Kyung Wook, Yoon, Sun-heui, Kim, Jin-Soo · 2016 · Nature Biotechnology
80. Gene regulation by the act of long non-coding RNA transcription
    Aleksandra E. Kornienko, Philipp M. Guenzl, Denise P. Barlow, Florian M. Pauler · 2013 · BMC Biology
81. Regulation of glucose homeostasis by glucocorticoids
    Kuo, Taiyi, McQueen, Allison, Chen, Tzu-Chieh, Wang, Jen-Chywan · 2015 · Advances in Experimental Medicine and Biology
82. A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi
    Christina Spuur Nødvig, Jakob Blæsbjerg Nielsen, Martin E. Kogle, Uffe Hasbro Mortensen · 2015 · PLoS ONE
83. A split-Cas9 architecture for inducible genome editing and transcription modulation
    Bernd Zetsche, Sara E. Volz, Feng Zhang · 2015 · Nature Biotechnology
84. Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA
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85. CRISPR/Cas9 for genome editing: progress, implications and challenges
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86. Three-dimensional organotypic culture: experimental models of mammalian biology and disease
    Shamir, Eliah R., Ewald, Andrew J. · 2014 · Nature Reviews Molecular Cell Biology
87. In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
    Kim, Eunji, Koo, Taeyoung, Park, Sung Wook, Kim, Daesik, Kim, Kyoungmi, Cho, Hee-Yeon, Song, Dong Woo, Lee, Kyu Jun, Jung, Min Hee, Kim, Seokjoong et al. · 2017 · Nature Communications
88. A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation
    Lowder, Levi G., Zhang, Dengwei, Baltes, Nicholas J., Paul, Joseph W., Tang, Xu, Zheng, Xuelian, Voytas, Daniel F., Hsieh, Tzung-Fu, Zhang, Yong, Qi, Yiping · 2015 · Plant Physiology
89. Advancing Crop Transformation in the Era of Genome Editing
    Fredy Altpeter, Nathan M. Springer, Laura Bartley, Ann E. Blechl, Thomas P. Brutnell, Vitaly Citovsky, Liza J. Conrad, Stanton B. Gelvin, David P. Jackson, Albert Paul Kausch et al. · 2016 · The Plant Cell
90. RNA-guided DNA insertion with CRISPR-associated transposases
    Jonathan Strecker, Alim Ladha, Zachary Gardner, Jonathan Leo Schmid-Burgk, Kira S. Makarova, Eugene V. Koonin, Feng Zhang · 2019 · Science
91. Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
    Prarthana Mohanraju, Kira S. Makarova, Bernd Zetsche, Feng Zhang, Eugene V. Koonin, John van der OOST · 2016 · Science
92. A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia
    Gröschel, Stefan, Sanders, Mathijs A., Hoogenboezem, Remco, de Wit, Elzo, Bouwman, Britta A.M., Erpelinck, Claudia, van der Velden, Vincent H.J., Havermans, Marije, Avellino, Roberto, van Lom, Kirsten et al. · 2014 · Cell
93. Synthetic lethality and cancer
    Nigel J. O’Neil, Melanie L. Bailey, Philip Hieter · 2017 · Nature Reviews Genetics
94. Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
    Andrea Ablasser, Jonathan Leo Schmid-Burgk, Inga Hemmerling, Gabor L Horvath, Tobias Schmidt, Eicke Latz, Veit Hornung · 2013 · Nature
95. Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
    Hou, Zhonggang, Zhang, Yan, Propson, Nicholas E., Howden, Sara E., Chu, Li-Fang, Sontheimer, Erik J., Thomson, James A. · 2013 · Proceedings of the National Academy of Sciences
96. Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system
    Mehdi Ghorbal, Molly Gorman, Cameron Ross MacPherson, Rafael Miyazawa Martins, Artur Scherf, José-Juan Lopez-Rubio · 2014 · Nature Biotechnology
97. Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
    Frock, Richard L, Hu, Jiazhi, Meyers, Robin M, Ho, Yu-Jui, Kii, Erina, Alt, Frederick W · 2015 · Nature Biotechnology
98. Rapid protein depletion in human cells by auxin-inducible degron tagging with short homology donors
    Natsume, Toyoaki, Kiyomitsu, Tomomi, Saga, Yumiko, Kanemaki, Masato T. · 2016 · Cell Reports
99. Targeted Mutagenesis in Zea mays Using TALENs and the CRISPR/Cas System
    Zhen Liang, Kang Zhang, Kunling Chen, Caixia Gao · 2013 · Journal of genetics and genomics/Journal of Genetics and Genomics
100. Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide
     Zhen Shi, Kotaro Fujii, Kyle M. Kovary, Naomi R. Genuth, Hannes Luc Röst, Mary N. Teruel, Maria Barna · 2017 · Molecular Cell