Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

QIIME allows analysis of high-throughput community sequencing data

Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887

Search and clustering orders of magnitude faster than BLAST

Edgar, R. C. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq461 · Cited by 21,098

Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy

Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 20,145

UCHIME improves sensitivity and speed of chimera detection

Edgar, R. C., Haas, B. J., Clemente, J. C., Quince, C., & Knight, R. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr381 · Cited by 15,114

Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB

DeSantis, T. Z., Hugenholtz, P., Larsen, N., Rojas, M., Brodie, E. L., Keller, K., Huber, T., Dalevi, D., Hu, P., & Andersen, G. L. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.03006-05 · Cited by 10,891

Ribosomal Database Project: data and tools for high throughput rRNA analysis

Cole, J. R., Wang, Q., Fish, J. A., Chai, B., McGarrell, D. M., Sun, Y., Brown, C. T., Porras‐Alfaro, A., Kuske, C. R., & Tiedje, J. M. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1244 · Cited by 4,480

Atopic Dermatitis: Global Epidemiology and Risk Factors

Nutten, S. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000370220 · Cited by 3,124

Topographical and Temporal Diversity of the Human Skin Microbiome

Grice, E. A., Kong, H. H., Conlan, S., Deming, C. B., Davis, J., Young, A. C., Program, N. C. S., Bouffard, G. G., Blakesley, R. W., Murray, P. R., et al. (2009) · Science · doi:10.1126/science.1171700 · Cited by 2,953

Differential abundance analysis for microbial marker-gene surveys

Paulson, J. N., Stine, O. C., Bravo, H. C., & Pop, M. (2013) · Nature Methods · doi:10.1038/nmeth.2658 · Cited by 2,471

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

Medema, M. H., Blin, K., Cimermančič, P., de Jager, V., Zakrzewski, P., Fischbach, M. A., Weber, T., Takano, E., & Breitling, R. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr466 · Cited by 2,067

Interaction between microbiota and immunity in health and disease

Zheng, D., Liwinski, T., & Elinav, E. (2020) · Cell Research · doi:10.1038/s41422-020-0332-7 · Cited by 3,947

The human skin microbiome

Byrd, A. L., Belkaid, Y., & Segre, J. A. (2018) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.157 · Cited by 2,806

Antimicrobial host defence peptides: functions and clinical potential

Mookherjee, N., Anderson, M. A., Haagsman, H. P., & Davidson, D. J. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0058-8 · Cited by 1,502

Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?

Akdiş, C. A. (2021) · Nature reviews. Immunology · doi:10.1038/s41577-021-00538-7 · Cited by 1,066

The gut microbiome: Relationships with disease and opportunities for therapy

Durack, J., & Lynch, S. V. (2018) · The Journal of Experimental Medicine · doi:10.1084/jem.20180448 · Cited by 979

Skin microbiota–host interactions

Chen, Y. E., Fischbach, M. A., & Belkaid, Y. (2018) · Nature · doi:10.1038/nature25177 · Cited by 815

The Dynamics of the Skin’s Immune System

Nguyen, A. V., & Soulika, A. M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20081811 · Cited by 759

Microbiota and maintenance of skin barrier function

Harris-Tryon, T. A., & Grice, E. A. (2022) · Science · doi:10.1126/science.abo0693 · Cited by 672

Shaping the Future of Probiotics and Prebiotics

Cunningham, M., Azcarate-Peril, M. A., Barnard, A., Benoit, V., Grimaldi, R., Guyonnet, D., Holscher, H. D., Hunter, K., Manurung, S., Obis, D., et al. (2021) · Trends in Microbiology · doi:10.1016/j.tim.2021.01.003 · Cited by 637

Pathophysiology of atopic dermatitis: Clinical implications

Kim, J., Kim, B. E., & Leung, D. Y. M. (2019) · Allergy and Asthma Proceedings · doi:10.2500/aap.2019.40.4202 · Cited by 655

Gut–Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions

Pessemier, B. D., Grine, L., Debaere, M., Maes, A., Paetzold, B., & Callewaert, C. (2021) · Microorganisms · doi:10.3390/microorganisms9020353 · Cited by 689

Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis

Byrd, A. L., Deming, C., Cassidy, S. K. B., Harrison, O. J., Ng, W.-I., Conlan, S., Program, N. C. S., Belkaid, Y., Segre, J. A., & Kong, H. H. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aal4651 · Cited by 607

New Insights into Human Nostril Microbiome from the Expanded Human Oral Microbiome Database (eHOMD): a Resource for the Microbiome of the Human Aerodigestive Tract

Escapa, I. F., Chen, T., Huang, Y., Gajare, P., Dewhirst, F. E., & Lemon, K. P. (2018) · mSystems · doi:10.1128/msystems.00187-18 · Cited by 615

The Evolution and Ecology of Bacterial Warfare

Granato, E. T., Meiller-Legrand, T. A., & Foster, K. R. (2019) · Current Biology · doi:10.1016/j.cub.2019.04.024 · Cited by 498

Mass spectrometry-based metabolomics in microbiome investigations

Bauermeister, A., Mannochio-Russo, H., Costa-Lotufo, L. V., Jarmusch, A. K., & Dorrestein, P. C. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00621-9 · Cited by 554

The microbiome in patients with atopic dermatitis

Paller, A. S., Kong, H. H., Seed, P., Naik, S., Scharschmidt, T. C., Gallo, R. L., Luger, T., & Irvine, A. D. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.11.015 · Cited by 525

Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship

Geoghegan, J. A., Irvine, A. D., & Foster, T. J. (2017) · Trends in Microbiology · doi:10.1016/j.tim.2017.11.008 · Cited by 533

The Immune Functions of Keratinocytes in Skin Wound Healing

Piipponen, M., Li, D., & Xu, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228790 · Cited by 550

Skin barrier immunity and ageing

Chambers, E. S., & Vukmanovic‐Stejic, M. (2019) · Immunology · doi:10.1111/imm.13152 · Cited by 534

Host–microbiota interactions in immune-mediated diseases

Ruff, W. E., Greiling, T. M., & Kriegel, M. A. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0367-2 · Cited by 503

γδ T cells in homeostasis and host defence of epithelial barrier tissues

Nielsen, M. M., Witherden, D. A., & Havran, W. L. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.101 · Cited by 479

Dupilumab with concomitant topical corticosteroid treatment in adults with atopic dermatitis with an inadequate response or intolerance to ciclosporin A or when this treatment is medically inadvisable: a placebo-controlled, randomized phase III clinical t

de Bruin-Weller, M. S., Thaçi, D., Smith, C. H., Reich, K., Cork, M. J., Radin, A. R., Zhang, Q., Akinlade, B. K., Gadkari, A., Eckert, L., et al. (2017) · British Journal of Dermatology · doi:10.1111/bjd.16156 · Cited by 485

Microbiota-mediated colonization resistance: mechanisms and regulation

Caballero-Flores, G., Pickard, J. M., & Núñez, G. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00833-7 · Cited by 474

Towards Optimal pH of the Skin and Topical Formulations: From the Current State of the Art to Tailored Products

Lukić, M. Ž., Pantelić, I., & Savic, S. D. (2021) · Cosmetics · doi:10.3390/cosmetics8030069 · Cited by 474

The atopic march and atopic multimorbidity: many trajectories, many pathways

Paller, A. S., Spergel, J. M., Mina-Osorio, P., & Irvine, A. D. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.11.006 · Cited by 464

The social network of microorganisms — how auxotrophies shape complex communities

Zengler, K., & Zaramela, L. S. (2018) · Nature Reviews Microbiology · doi:10.1038/s41579-018-0004-5 · Cited by 459

Microbe-host interplay in atopic dermatitis and psoriasis

Fyhrquist, N., Muirhead, G., Prast‐Nielsen, S., Jeanmougin, M., Oláh, P., Skoog, T., Jules-Clément, G., Feld, M., Barrientos‐Somarribas, M., Sinkko, H., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12253-y · Cited by 419

Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

Fugger, L. H., Jensen, L. T., & Rossjohn, J. (2020) · Cell · doi:10.1016/j.cell.2020.03.007 · Cited by 415

The microbiome-shaping roles of bacteriocins

Heilbronner, S., Krismer, B., Brötz‐Oesterhelt, H., & Peschel, A. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00569-w · Cited by 416

Significance of Skin Barrier Dysfunction in Atopic Dermatitis

Kim, B. E., & Leung, D. Y. M. (2018) · Allergy, Asthma & Immunology Research · doi:10.4168/aair.2018.10.3.207 · Cited by 393

Type 2 immunity in allergic diseases

Öğülür, İ., Mitamura, Y., Yazıcı, D., Pat, Y., Ardıçlı, S., Li, M., D’Avino, P., Beha, C., Babayev, H., Zhao, B., et al. (2025) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01261-2 · Cited by 453

Interleukin‐13: Targeting an underestimated cytokine in atopic dermatitis

Bieber, T. (2020) · Allergy · doi:10.1111/all.13954 · Cited by 382

The commensal lifestyle of Staphylococcus aureus and its interactions with the nasal microbiota

Krismer, B., Weidenmaier, C., Zipperer, A., & Peschel, A. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.104 · Cited by 395

Staphylococcus epidermidis and its dual lifestyle in skin health and infection

Severn, M. M., & Horswill, A. R. (2022) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00780-3 · Cited by 408

Human Skin Microbiome: Impact of Intrinsic and Extrinsic Factors on Skin Microbiota

Skowron, K., Bauza-Kaszewska, J., Kraszewska, Z., Wiktorczyk-Kapischke, N., Grudlewska‐Buda, K., Kwiecińska-Piróg, J., Wałecka-Zacharska, E., Radtke, L., & Gospodarek-Komkowska, E. (2021) · Microorganisms · doi:10.3390/microorganisms9030543 · Cited by 373

Host-microbiome interactions and recent progress into understanding the biology of acne vulgaris

O’Neill, A. M., & Gallo, R. L. (2018) · Microbiome · doi:10.1186/s40168-018-0558-5 · Cited by 334

Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial

Nakatsuji, T., Hata, T. R., Tong, Y., Cheng, J. Y., Shafiq, F., Butcher, A. M., Salem, S. S., Brinton, S. L., Rudman Spergel, A. K., Johnson, K., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01256-2 · Cited by 333

The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

Huang, Y. J., Marsland, B. J., Bunyavanich, S., O'Mahony, L., Leung, D. Y. M., Muraro, A., & Fleisher, T. A. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.02.007 · Cited by 330

First-in-human topical microbiome transplantation with Roseomonas mucosa for atopic dermatitis

Myles, I. A., Earland, N. J., Anderson, E. D., Moore, I. N., Kieh, M. D., Williams, K. W., Saleem, A., Fontecilla, N. M., Welch, P. A., Darnell, D. A., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.120608 · Cited by 332

Microbiome in the gut-skin axis in atopic dermatitis

Lee, S.-Y., Lee, E., Park, Y. M., & Hong, S.-J. (2018) · Allergy, Asthma & Immunology Research · doi:10.4168/aair.2018.10.4.354 · Cited by 326

A commensal strain of Staphylococcus epidermidis protects against skin neoplasia

Nakatsuji, T., Chen, T. H., Butcher, A. M., Trzoss, L., Nam, S., Shirakawa, K. T., Zhou, W. L., Oh, J., Otto, M. J., Fenical, W., et al. (2018) · Science Advances · doi:10.1126/sciadv.aao4502 · Cited by 333

Skin Barrier Function and the Microbiome

Lee, H.-J., & Kim, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113071 · Cited by 317

Cutaneous Barriers and Skin Immunity: Differentiating A Connected Network

Eyerich, S., Eyerich, K., Traidl‐Hoffmann, C., & Biedermann, T. (2018) · Trends in Immunology · doi:10.1016/j.it.2018.02.004 · Cited by 327

Gut microbiota as a source of novel antimicrobials

García-Gutiérrez, E., Mayer, M. J., Cotter, P. D., & Narbad, A. (2018) · Gut Microbes · doi:10.1080/19490976.2018.1455790 · Cited by 306

Acne, the Skin Microbiome, and Antibiotic Treatment

Xu, H., & Li, H. (2019) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-00417-3 · Cited by 317

Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis

Williams, M. R., Costa, S. K., Zaramela, L. S., Khalil, S., Todd, D. A., Winter, H. L., Sanford, J. A., O’Neill, A. M., Liggins, M. C., Nakatsuji, T., et al. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aat8329 · Cited by 292

Atopic dermatitis: the skin barrier and beyond

Tsakok, T., Woolf, R., Smith, C. H., Weidinger, S., & Flohr, C. (2018) · British Journal of Dermatology · doi:10.1111/bjd.16934 · Cited by 298

Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides

Zheng, Y., Hunt, R. L., Villaruz, A. E., Fisher, E. L., Liu, R., Liu, Q., Cheung, G. Y. C., Li, M., & Otto, M. J. (2022) · Cell Host & Microbe · doi:10.1016/j.chom.2022.01.004 · Cited by 301

Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus

Kim, S. G., Becattini, S., Moody, T. U., Shliaha, P. V., Littmann, E. R., Seok, R., Gjonbalaj, M., Eaton, V. P., Fontana, E., Amoretti, L. A., et al. (2019) · Nature · doi:10.1038/s41586-019-1501-z · Cited by 290

The Skin Microbiota: Balancing Risk and Reward

Flowers, L. J., & Grice, E. A. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.06.017 · Cited by 302

Commensal Staphylococci Influence Staphylococcus aureus Skin Colonization and Disease

Parlet, C. P., Severn, M. M., & Horswill, A. R. (2019) · Trends in Microbiology · doi:10.1016/j.tim.2019.01.008 · Cited by 289

Major Comorbidities of Atopic Dermatitis: Beyond Allergic Disorders

Paller, A. S., Jaworski, J. C., Simpson, E. L., Boguniewicz, M., Russell, J. J., Block, J. K., Tofte, S. J., Dunn, J. D., Feldman, S. R., Clark, A. R., et al. (2018) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-0383-4 · Cited by 285

The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent

Ridyard, K. E., & Overhage, J. (2021) · Antibiotics · doi:10.3390/antibiotics10060650 · Cited by 283

A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation

Ma, Z., Zuo, T., Frey, N., & Rangrez, A. Y. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01946-6 · Cited by 322

Epithelial barrier repair and prevention of allergy

Goleva, E., Berdyshev, E., & Leung, D. Y. M. (2019) · Journal of Clinical Investigation · doi:10.1172/jci124608 · Cited by 251

Type 2 Inflammation Contributes to Skin Barrier Dysfunction in Atopic Dermatitis

Beck, L. A., Cork, M. J., Amagai, M., Benedetto, A. D., Kabashima, K., Hamilton, J. D., & Rossi, A. B. (2022) · JID Innovations · doi:10.1016/j.xjidi.2022.100131 · Cited by 268

Challenges in exploring and manipulating the human skin microbiome

Boxberger, M., Cenizo, V., Cassir, N., & La Scola, B. (2021) · Microbiome · doi:10.1186/s40168-021-01062-5 · Cited by 247

Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing

Paharik, A. E., Parlet, C. P., Chung, N., Todd, D. A., Rodriguez, E. I., Dyke, M. J. V., Cech, N. B., & Horswill, A. R. (2017) · Cell Host & Microbe · doi:10.1016/j.chom.2017.11.001 · Cited by 242

Microbiome of the Skin and Gut in Atopic Dermatitis (AD): Understanding the Pathophysiology and Finding Novel Management Strategies

Kim, J. E., & Kim, H. S. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8040444 · Cited by 249

The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment

Facheris, P., Jeffery, J., DUCA, E. D., & Guttman‐Yassky, E. (2023) · Cellular and Molecular Immunology · doi:10.1038/s41423-023-00992-4 · Cited by 255

The impact of skin care products on skin chemistry and microbiome dynamics

Bouslimani, A., da Silva, R., Kosciolek, T., Janssen, S., Callewaert, C., Amir, A., Dorrestein, K., Melnik, A. V., Zaramela, L. S., Kim, J.-N., et al. (2019) · BMC Biology · doi:10.1186/s12915-019-0660-6 · Cited by 234

The Skin and Gut Microbiome and Its Role in Common Dermatologic Conditions

Ellis, S. R., Nguyen, M., Vaughn, A. R., Notay, M., Burney, W. A., Sandhu, S., & Sivamani, R. K. (2019) · Microorganisms · doi:10.3390/microorganisms7110550 · Cited by 242

Staphylococcus epidermidis and Cutibacterium acnes: Two Major Sentinels of Skin Microbiota and the Influence of Cosmetics

Fournière, M., Latire, T., Souak, D., Feuilloley, M. G. J., & Bedoux, G. (2020) · Microorganisms · doi:10.3390/microorganisms8111752 · Cited by 227

Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

McLaughlin, J. B., Watterson, S., Layton, A., Bjourson, A. J., Barnard, E., & McDowell, A. (2019) · Microorganisms · doi:10.3390/microorganisms7050128 · Cited by 233

IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis

Callewaert, C., Nakatsuji, T., Knight, R. D., Kościółek, T., Vrbanac, A. F., Kotol, P. F., Ardeleanu, M., Hultsch, T., Guttman‐Yassky, E., Bissonnette, R., et al. (2019) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.05.024 · Cited by 229

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype

Leung, D. Y. M., Calatroni, A., Zaramela, L. S., LeBeau, P. K., Dyjack, N., Brar, K., David, G., Johnson, K., Leung, S., Ramirez-Gama, M., et al. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aav2685 · Cited by 214

Bacterial Biofilm in Chronic Wounds and Possible Therapeutic Approaches

Cavallo, I., Sivori, F., Mastrofrancesco, A., Abril, E., Pontone, M., Domenico, E. G. D., & Pimpinelli, F. (2024) · Biology · doi:10.3390/biology13020109 · Cited by 234

Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents

Luger, T. A., Amagai, M., Dréno, B., Dagnelie, M., Liao, W. J., Kabashima, K., Schikowski, T., Proksch, E., Elias, P. M., Simon, M., et al. (2021) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2021.04.007 · Cited by 227

Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications

Kim, J., Kim, B. E., Ahn, K., & Leung, D. Y. M. (2019) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2019.11.5.593 · Cited by 212

The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group

Alexander, H., Paller, A. S., Traidl‐Hoffmann, C., Beck, L. A., Benedetto, A. D., Dhar, S., Girolomoni, G., Irvine, A. D., Spuls, P. I., Su, J. C., et al. (2019) · British Journal of Dermatology · doi:10.1111/bjd.18643 · Cited by 218

New treatments in atopic dermatitis

Puar, N. K., Chovatiya, R., & Paller, A. S. (2020) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2020.08.016 · Cited by 207

Commensal microbiota modulate gene expression in the skin

Meisel, J. S., Sfyroera, G., Bartow-McKenney, C., Gimblet, C., Bugayev, J., Horwinski, J., Kim, B., Brestoff, J. R., Tyldsley, A. S., Zheng, Q., et al. (2018) · Microbiome · doi:10.1186/s40168-018-0404-9 · Cited by 201

Report from the National Institute of Allergy and Infectious Diseases workshop on “Atopic dermatitis and the atopic march: Mechanisms and interventions”

Davidson, W. F., Leung, D. Y. M., Beck, L. A., Berin, M. C., Boguniewicz, M., Busse, W. W., Chatila, T. A., Geha, R. S., Gern, J. E., Guttman‐Yassky, E., et al. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2019.01.003 · Cited by 204

Therapeutic pipeline for atopic dermatitis: End of the drought?

Paller, A. S., Kabashima, K., & Bieber, T. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.07.006 · Cited by 192

Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration

Baurecht, H., Rühlemann, M. C., Rodríguez, E., Thielking, F., Harder, I., Erkens, A., Stölzl, D., Ellinghaus, E., Hotze, M., Lieb, W., et al. (2018) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.01.019 · Cited by 197

Staphylococcus epidermidis—Skin friend or foe?

Severn, M. M., & Horswill, A. R. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1009026 · Cited by 205

The Skin Microbiome: Current Landscape and Future Opportunities

Smythe, P., & Wilkinson, H. N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043950 · Cited by 218

Cutaneous barrier dysfunction in allergic diseases

Leung, D. Y. M., Berdyshev, E., & Goleva, E. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2020.02.021 · Cited by 190

Patients with Atopic Dermatitis Colonized with Staphylococcus aureus Have a Distinct Phenotype and Endotype

Simpson, E. L., Villarreal, M., Jepson, B. M., Rafaels, N., David, G. L., Hanifin, J. M., Taylor, P. A., Boguniewicz, M., Yoshida, T., Benedetto, A. D., et al. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.03.1517 · Cited by 197

Staphylococcus epidermidis protease EcpA can be a deleterious component of the skin microbiome in atopic dermatitis

Cau, L., Williams, M. R., Butcher, A. M., Nakatsuji, T., Kavanaugh, J. S., Cheng, J. Y., Shafiq, F., Higbee, K., Hata, T. R., Horswill, A. R., et al. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2020.06.024 · Cited by 193

A Vehicle‐Free Antimicrobial Polymer Hybrid Gold Nanoparticle as Synergistically Therapeutic Platforms for Staphylococcus aureus Infected Wound Healing

He, X., Dai, L., Ye, L., Sun, X., Obeng, E., Hu, R., Zan, X., Lin, F., & Shen, J. (2022) · Advanced Science · doi:10.1002/advs.202105223 · Cited by 190

Staphylococcus aureus colonisation and strategies for decolonisation

Piewngam, P., & Otto, M. J. (2024) · The Lancet Microbe · doi:10.1016/s2666-5247(24)00040-5 · Cited by 192

From Dysbiosis to Healthy Skin: Major Contributions of Cutibacterium acnes to Skin Homeostasis

Rozas, M., de Ruijter, A. B. P. H., Fábrega, M.-J., Zorgani, A., Güell, M., Paetzold, B., & Brillet, F. (2021) · Microorganisms · doi:10.3390/microorganisms9030628 · Cited by 190

Living in Your Skin: Microbes, Molecules, and Mechanisms

Swaney, M. H., & Kalan, L. (2021) · Infection and Immunity · doi:10.1128/iai.00695-20 · Cited by 201

Skin microbiome of atopic dermatitis

Koh, L. F., Ong, R. Y., & Common, J. (2021) · Allergology International · doi:10.1016/j.alit.2021.11.001 · Cited by 194

Interplay between gut microbiota and antimicrobial peptides

Zong, X., Fu, J., Xu, B., Wang, Y., & Jin, M. (2020) · Animal nutrition · doi:10.1016/j.aninu.2020.09.002 · Cited by 193

Probiotics or pro‐healers: the role of beneficial bacteria in tissue repair

Lukić, J., Chen, V., Strahinić, I., Begović, J., Lev‐Tov, H. A., Davis, S. C., Tomic‐Canic, M., & Pastar, I. (2017) · Wound Repair and Regeneration · doi:10.1111/wrr.12607 · Cited by 180

Skin Microbiome in Atopic Dermatitis

Edslev, S. M., Agner, T., & Andersen, P. S. (2020) · Acta Dermato Venereologica · doi:10.2340/00015555-3514 · Cited by 194

Skin and Gut Microbiome in Psoriasis: Gaining Insight Into the Pathophysiology of It and Finding Novel Therapeutic Strategies

Chen, L., Li, J., Zhu, W., Kuang, Y., Liu, T., Zhang, W., Chen, X., & Peng, C. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.589726 · Cited by 175

A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles

Claesen, J., Spagnolo, J., Ramos, S. F., Kurita, K. L., Byrd, A. L., Aksenov, A. A., Melnik, A. V., Wong, W. R., Wang, S., Hernandez, R. D., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay5445 · Cited by 166

The skin microbiome and the gut-skin axis

Sinha, S., Lin, G. H. Y., & Ferenczi, K. (2021) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2021.08.021 · Cited by 199

The Human Skin Microbiome in Selected Cutaneous Diseases

Carmona-Cruz, S., Orozco-Covarrubias, L., & Sáez-de-Ocariz, M. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.834135 · Cited by 170

Association of Disease Severity With Skin Microbiome and Filaggrin Gene Mutations in Adult Atopic Dermatitis

Clausen, M., Agner, T., Lilje, B., Edslev, S. M., Johannesen, T. B., & Andersen, P. S. (2018) · JAMA Dermatology · doi:10.1001/jamadermatol.2017.5440 · Cited by 168

Immunologic, microbial, and epithelial interactions in atopic dermatitis

Brunner, P. M., Leung, D. Y. M., & Guttman‐Yassky, E. (2017) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2017.09.055 · Cited by 166

The role of the skin microbiome in atopic dermatitis

Nakatsuji, T., & Gallo, R. L. (2018) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2018.12.003 · Cited by 167

Human skin microbiota is a rich source of bacteriocin-producing staphylococci that kill human pathogens

O'Sullivan, J. N., Rea, M. C., O’Connor, P. M., Hill, C., & Ross, R. P. (2018) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiy241 · Cited by 171

Unmet medical needs in chronic, non-communicable inflammatory skin diseases

Ujiie, H., Rosmarin, D., Schön, M. P., Ständer, S., Boch, K., Metz, M., Maurer, M., Thaci, D., Schmidt, E., Cole, C., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.875492 · Cited by 158

Cutaneous Malassezia: Commensal, Pathogen, or Protector?

Chandra, S. H. V., Srinivas, R., Dawson, T. L., & Common, J. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.614446 · Cited by 164

Elucidation of complexity and prediction of interactions in microbial communities

Zúñiga, C., Zaramela, L. S., & Zengler, K. (2017) · Microbial Biotechnology · doi:10.1111/1751-7915.12855 · Cited by 159

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Biazzo, M., & Deidda, G. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11144119 · Cited by 172

Skin’s Natural Bacteria May Protect Against Pathogens

Hampton, T. (2017) · JAMA · doi:10.1001/jama.2017.3111

Le microbiote cutané: le poids lourd sort de l'ombre [The skin microbiota: a colossus steps into the spotlight]

Di Domizio, J., Pagnoni, A., Huber, M., Hohl, D., & Gilliet, M. (2016) · SERVAL (Université de Lausanne)

Bacterial battles on your skin

Pujanandez, L. (2017) · Science · doi:10.1126/science.355.6327.808-b

Skin cream kills pathogen

(2017) · Nature · doi:10.1038/543008d

The role of skin dysbiosis in atopic dermatitis

Braun, C., Patra, V., Lina, G., Nicolas, J., Vocanson, M., & Nosbaum, A. (2022) · European Journal of Dermatology · doi:10.1684/ejd.2022.4289 · Cited by 12