Schizophrenia as a Disorder of Neurodevelopment

Implications of Normal Brain Development for the Pathogenesis of Schizophrenia

Weinberger, D. R. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800190080012 · Cited by 3,724 · see citing works

The Molecular Biology of Axon Guidance

Tessier‐Lavigne, M., & Goodman, C. S. (1996) · Science · doi:10.1126/science.274.5290.1123 · Cited by 3,295 · see citing works

Synaptic density in human frontal cortex —Developmental changes and effects of aging

Peter R., H. (1979) · Brain Research · doi:10.1016/0006-8993(79)90349-4 · Cited by 2,645 · see citing works

A review of MRI findings in schizophrenia

Shenton, M. E., Dickey, C. C., Frumin, M., & McCarley, R. W. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00163-3 · Cited by 2,346 · see citing works

Neuronal specification in the spinal cord: inductive signals and transcriptional codes

Jessell, T. M. (2000) · Nature Reviews Genetics · doi:10.1038/35049541 · Cited by 2,089 · see citing works

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

Kuida, K., Zheng, T. S., Na, S., Kuan, C.-Y., Yang, D., Karasuyama, H., RAKIC, P. T., & Flavell, R. A. (1996) · Nature · doi:10.1038/384368a0 · Cited by 1,881 · see citing works

Searching for genetic determinants in the new millennium

Risch, N. J. (2000) · Nature · doi:10.1038/35015718 · Cited by 1,839 · see citing works

Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?

Feinberg, I. (1982) · Journal of Psychiatric Research · doi:10.1016/0022-3956(82)90038-3 · Cited by 1,395 · see citing works

Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

Crawley, J. N., Belknap, J. K., Collins, A. C., Crabbe, J. C., Frankel, W. N., Henderson, N. D., HITZEMANN, R. J., Maxson, S. C., Miner, L. L., Silva, A. J., et al. (1997) · Psychopharmacology · doi:10.1007/s002130050327 · Cited by 1,372 · see citing works

Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort

JONES, P. (1994) · The Lancet · doi:10.1016/s0140-6736(94)90569-x · Cited by 1,353 · see citing works

Decrease in Reelin and Glutamic Acid Decarboxylase67 (GAD67) Expression in Schizophrenia and Bipolar Disorder

Guidotti, A., Auta, J., Davis, J. M., Gerevini, V. D. G., Dwivedi, Y., Grayson, D. R., Impagnatiello, F., Pandey, G. N., Pesold, C., Sharma, R. P., et al. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.11.1061 · Cited by 1,203 · see citing works

Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic

Mednick, S. A. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800260109013 · Cited by 1,198 · see citing works

Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex

Rakic, P., Bourgeois, J.-P., Eckenhoff, M. F., Zecevic, N., & Goldman-Rakic, P. S. (1986) · Science · doi:10.1126/science.3952506 · Cited by 1,133 · see citing works

Molecular Characterization of Schizophrenia Viewed by Microarray Analysis of Gene Expression in Prefrontal Cortex

Mirnics, K., Middleton, F. A., Marquez, A., Lewis, D. A., & Levitt, P. (2000) · Neuron · doi:10.1016/s0896-6273(00)00085-4 · Cited by 882 · see citing works

Prenatal developmental disturbances in the limbic allocortex in schizophrenics

Jakob, H., & Beckmann, H. (1986) · Journal of Neural Transmission · doi:10.1007/bf01249090 · Cited by 875 · see citing works

Schizophrenia genesis: the origins of madness

(1991) · Choice Reviews Online · doi:10.5860/choice.28-6500 · Cited by 832 · see citing works

Effects of Family History and Place and Season of Birth on the Risk of Schizophrenia

Mortensen, P. B., Pedersen, C. B., Westergaard, T., Wohlfahrt, J., Ewald, H., Mors, O. N., Andersen, P. K., & Melbye, M. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902253400803 · Cited by 822 · see citing works

Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia

Thompson, P. M., Vidal, C., Giedd, J. N., Gochman, P., Blumenthal, J., Nicolson, R., Toga, A. W., & Rapoport, J. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.201243998 · Cited by 812 · see citing works

Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests1Published on the World Wide Web on 2 December 1998.1

Crawley, J. N. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01258-x · Cited by 762 · see citing works

Schizophrenia After Prenatal Famine

Susser, E. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830010027005 · Cited by 741 · see citing works

Neocortex Patterning by the Secreted Signaling Molecule FGF8

Fukuchi-Shimogori, T., & Grove, E. (2001) · Science · doi:10.1126/science.1064252 · Cited by 707 · see citing works

Altered Distribution of Nicotinamide-Adenine Dinucleotide Phosphate—Diaphorase Cells in Frontal Lobe of Schizophrenics Implies Disturbances of Cortical Development

Akbarian, S. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820150007001 · Cited by 679 · see citing works

To Model a Psychiatric Disorder in Animals Schizophrenia As a Reality Test

Lipska, B. K. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00137-8 · Cited by 650 · see citing works

Schizophrenia as a Disorder of Developmentally Reduced Synaptic Connectivity

McGlashan, T. H. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.7.637 · Cited by 645 · see citing works

Seasonality of births in schizophrenia and bipolar disorder: a review of the literature

Torrey, Ε. F., Miller, J., Rawlings, R. R., & Yolken, R. H. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(97)00092-3 · Cited by 639 · see citing works

Evidence of a Dose-Response Relationship Between Urbanicity During Upbringing and Schizophrenia Risk

Pedersen, C. B. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.11.1039 · Cited by 631 · see citing works

Behavioral and Intellectual Markers for Schizophrenia in Apparently Healthy Male Adolescents

Davidson, M., Reichenberg, A., Rabinowitz, J., Weiser, M., Kaplan, Z., & Mark, M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.9.1328 · Cited by 582 · see citing works

Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality

Hirotsune, S., Fleck, M. W., Gambello, M. J., Bix, G. J., Chen, A. Y.-C., Clark, G., Ledbetter, D. H., McBain, C. J., & Wynshaw-Boris, A. J. (1998) · Nature Genetics · doi:10.1038/1221 · Cited by 575 · see citing works

Some Cytoarchitectural Abnormalities of the Entorhinal Cortex in Schizophrenia

Arnold, S. E. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810310043008 · Cited by 525 · see citing works

A Neurodevelopmental Approach to the Classification of Schizophrenia

Murray, R. M., O’Callaghan, E., Castle, D. J., & Lewis, S. W. (1992) · Schizophrenia Bulletin · doi:10.1093/schbul/18.2.319 · Cited by 516 · see citing works

Location of a Major Susceptibility Locus for Familial Schizophrenia on Chromosome 1q21-q22

Brzustowicz, L. M., Hodgkinson, K. A., Chow, E. W. C., Honer, W. G., & Bassett, A. S. (2000) · Science · doi:10.1126/science.288.5466.678 · Cited by 516 · see citing works

Maternal Infections and Subsequent Psychosis Among Offspring

Buka, S. L. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.11.1032 · Cited by 512 · see citing works

Schizophrenia as a Long-Term Outcome of Pregnancy, Delivery, and Perinatal Complications: A 28-Year Follow-Up of the 1966 North Finland General Population Birth Cohort

Jones, P. B., Rantakallio, P. T., Hartikainen, A., Isohanni, M. K., & Sipilä, P. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.3.355 · Cited by 508 · see citing works

Childhood antecedents of schizophrenia and affective illness: social adjustment at ages 7 and 11

Done, D. J., Crow, T. J., Johnstone, E. C., & Sacker, A. (1994) · BMJ · doi:10.1136/bmj.309.6956.699 · Cited by 487 · see citing works

The neurodevelopmental hypothesis of schizophrenia: Following a trail of evidence from cradle to grave

Marenco, S., & Weinberger, D. R. (2000) · Development and Psychopathology · doi:10.1017/s0954579400003138 · Cited by 482 · see citing works

IQ and risk for schizophrenia: a population-based cohort study

David, A. S., Malmberg, A., Brandt, L. J., Alle­beck, P., & Lewis, G. (1997) · Psychological Medicine · doi:10.1017/s0033291797005680 · Cited by 467 · see citing works

Epidemiology of schizophrenia: the global burden of disease and disability

Jablensky, A. V. (2000) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s004060070002 · Cited by 465 · see citing works

Confirming Unexpressed Genotypes for Schizophrenia

Gottesman, I. I. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810100009002 · Cited by 454 · see citing works

Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression

Fatemi, S. H., Earle, J. A., & McMenomy, T. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000783 · Cited by 447 · see citing works

Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia

Mirnics, K., Middleton, F. A., Stanwood, G. D., Lewis, D. A., & Levitt, P. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000866 · Cited by 446 · see citing works

Neuromotor Precursors of Schizophrenia

Walker, E. F., Savoie, T. M., & Davis, D. (1994) · Schizophrenia Bulletin · doi:10.1093/schbul/20.3.441 · Cited by 445 · see citing works

Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

Middleton, F. A., Mirnics, K., Pierri, J. N., Lewis, D. A., & Levitt, P. R. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-07-02718.2002 · Cited by 428 · see citing works

Is Schizophrenia a Progressive Neurodevelopmental Disorder? Toward a Unitary Pathogenetic Mechanism

Woods, B. T. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.12.1661 · Cited by 413 · see citing works

Glutamate receptor expression in schizophrenic brain

Meador‐Woodruff, J. H. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00044-2 · Cited by 412 · see citing works

Obstetric Complications and Schizophrenia: A Meta-Analysis

Geddes, J., & Lawrie, S. M. (1995) · The British Journal of Psychiatry · doi:10.1192/bjp.167.6.786 · Cited by 405 · see citing works

Maldistribution of Interstitial Neurons in Prefrontal White Matter of the Brains of Schizophrenic Patients

Akbarian, S. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830050061010 · Cited by 398 · see citing works

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

Mirnics, K., Middleton, F. A., Lewis, D. A., & Levitt, P. R. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01862-2 · Cited by 393 · see citing works

Association and linkage analyses of RGS4 polymorphisms in schizophrenia

Chowdari, K. V. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.12.1373 · Cited by 368 · see citing works

Infants at Risk for Schizophrenia: Sequelae of a Genetic Neurointegrative Defect

Fish, B. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820030053007 · Cited by 357 · see citing works

RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K + channels

Doupnik, C. A., Davidson, N., Lester, H. A., & Kofuji, P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10461 · Cited by 337 · see citing works

Cell biology of the hippocampal formation in schizophrenia

Weinberger, D. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00331-x · Cited by 321 · see citing works

Response Diversity and the Timing of Progenitor Cell Maturation Are Regulated by Developmental Changes in EGFR Expression in the Cortex

Burrows, R. C., Wancio, D., Levitt, P. R., & Lillien, L. E. (1997) · Neuron · doi:10.1016/s0896-6273(00)80937-x · Cited by 320 · see citing works

Genes, environment and schizophrenia

Tsuang, M. T., Stone, W. S., & Faraone, S. V. (2001) · The British Journal of Psychiatry · doi:10.1192/bjp.178.40.s18 · Cited by 304 · see citing works

Obstetric complications and age at onset in schizophrenia: an international collaborative meta-analysis of individual patient data

Verdoux, H., Geddes, J. R., Takei, N., Lawrie, S. M., Bovet, P., Eagles, J., Heun, R., McCreadie, R. G., McNeil, T. F., O’Callaghan, E., et al. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.9.1220 · Cited by 296 · see citing works

Urbanization and psychosis: a study of 1942–1978 birth cohorts in The Netherlands

Marcelis, M. C., Navarro‐Mateu, F., Murray, R. M., Selten, J., & van Os, J. (1998) · Psychological Medicine · doi:10.1017/s0033291798006898 · Cited by 294 · see citing works

Premorbid adjustment and personality in people with schizophrenia†

Malmberg, A., Lewis, G., David, A., & Allebeck, P. (1998) · British Journal of Psychiatry · doi:10.1192/bjp.172.4.308 · Cited by 261 · see citing works

Altered GABA neurotransmission and prefrontal cortical dysfunction in schizophrenia

Lewis, D. A., Pierri, J. N., Volk, D. W., Melchitzky, D. S., & Woo, T.-U. W. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00061-x · Cited by 256 · see citing works

Changes in retinal cell fate induced by overexpression of EGF receptor

Lillien, L. E. (1995) · Nature · doi:10.1038/377158a0 · Cited by 248 · see citing works

Mental Illness in the Biological and Adoptive Families of Adopted Schizophrenics

Kety, S. S., ROSENTHAL, D., Wender, P. H., & D, F. S. M. (1971) · American Journal of Psychiatry · doi:10.1176/ajp.128.3.302 · Cited by 235 · see citing works

Complications of pregnancy and delivery in relation to psychosis in adult life: data from the British perinatal mortality survey sample.

Done, D. J., Johnstone, E. C., Frith, C., Golding, J., Shepherd, P., & Crow, T. J. (1991) · BMJ · doi:10.1136/bmj.302.6792.1576 · Cited by 221 · see citing works

Nonaffective Psychosis After Prenatal Exposure to Rubella

Brown, A. S., Cohen, P., Greenwald, S., & Susser, E. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.3.438 · Cited by 219 · see citing works

Developmentally Moderated Expressions of the Neuropathology Underlying Schizophrenia

Walker, E. F. (1994) · Schizophrenia Bulletin · doi:10.1093/schbul/20.3.453 · Cited by 216 · see citing works

Premorbid Social Underachievement in Schizophrenia

Jones, P. B., Bebbington, P., Foerster, A., Lewis, S. W., Murray, R. M., Russell, A., Sham, P. C., Toone, B., & Wilkins, S. (1993) · The British Journal of Psychiatry · doi:10.1192/bjp.162.1.65 · Cited by 206 · see citing works

Relationship of Obstetric Complications and Differences in Size of Brain Structures in Monozygotic Twin Pairs Discordant for Schizophrenia

McNeil, T. F., Cantor‐Graae, E., & Weinberger, D. R. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.2.203 · Cited by 206 · see citing works

Protein–Protein interactions, cytoskeletal regulation and neuronal migration

Feng, Y., & Walsh, C. A. (2001) · Nature reviews. Neuroscience · doi:10.1038/35077559 · Cited by 205 · see citing works

Absence of Neurodegeneration and Neural Injury in the Cerebral Cortex in a Sample of Elderly Patients With Schizophrenia

Arnold, S. E., Trojanowski, J. Q., Gur, R. E., Blackwell, P., Han, L., & Choi, C. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.3.225 · Cited by 199 · see citing works

Regionally Specific Neuronal Pathology in Untreated Patients with Schizophrenia: A Proton Magnetic Resonance Spectroscopic Imaging Study

Bertolino, A., Callicott, J. H., Elman, I., Mattay, V. S., Tedeschi, G., Frank, J. A., Breier, A. F., & Weinberger, D. R. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00555-6 · Cited by 198 · see citing works

Risk Factors of Psychosis: Identifying Vulnerable Populations Premorbidly

Olin, S.-C. S., & Mednick, S. A. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.2.223 · Cited by 188 · see citing works

Pregnancy/Delivery Complications and Psychiatric Diagnosis

Buka, S. L. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820140077009 · Cited by 183 · see citing works

Adult phenotype in the mouse can be affected by epigenetic events in the early embryo

Reik, W., Römer, I., Barton, S. C., Surani, M. A., Howlett, S., & Klose, J. (1993) · Development · doi:10.1242/dev.119.3.933 · Cited by 182 · see citing works

Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

Zindy, F., Cunningham, J. J., Sherr, C. J., Jogal, S., Smeyne, R. J., & Roussel, M. F. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13462 · Cited by 172 · see citing works

Family and twin strategies as a head start in defining prodromes and endophenotypes for hypothetical early-interventions in schizophrenia.

Gottesman, I. I., & Erlenmeyer‐Kimling, L. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00245-6 · Cited by 159 · see citing works

Reelin Is a Serine Protease of the Extracellular Matrix

Quattrocchi, C. C., Wannenes, F., Persico, A. M., Ciafré, S. A., D'Arcangelo, G., Farace, M. G., & Keller, F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106996200 · Cited by 154 · see citing works

IQ Decline During Childhood and Adult Psychotic Symptoms in a Community Sample: A 19-Year Longitudinal Study

Kremen, W. S., Buka, S. L., Seidman, L. J., Goldstein, J. M., Koren, D., & Tsuang, M. T. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.5.672 · Cited by 146 · see citing works

Minor Physical Anomalies in Schizophrenia Patients, Bipolar Patients, and Their Siblings

Green, M. F., Satz, P., & Christenson, C. (1994) · Schizophrenia Bulletin · doi:10.1093/schbul/20.3.433 · Cited by 144 · see citing works

School performance as a predictor of psychiatric hospitalization in adult life. A 28-year follow-up in the Northern Finland 1966 Birth Cohort

Isohanni, I., Järvelin, M., Nieminen, P., Jones, P., Rantakallio, P., Jokelainen, J., & Isohanni, M. (1998) · Psychological Medicine · doi:10.1017/s0033291798006928 · Cited by 135 · see citing works

Brain macrophages and microglia respond differently to lesions of the developing and adult visual system

Milligan, C. E., Levitt, P. R., & Cunningham, T. J. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903140113 · Cited by 135 · see citing works

Obstetric complications and congenital malformation in schizophrenia

McNeil, T. F. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00034-x · Cited by 133 · see citing works

Cognitive impairment and negative symptoms in geriatric chronic schizophrenic patients: a follow-up study

Harvey, P. D., Lombardi, J., Leibman, M., WHITE, L. E., Parrella, M. J., Powchik, P., & Davidson, M. (1996) · Schizophrenia Research · doi:10.1016/s0920-9964(96)00075-8 · Cited by 130 · see citing works

Schizophrenia: A Neurodevelopmental Perspective

Pilowsky, L. S., Kerwin, R. W., & Murray, R. M. (1993) · Neuropsychopharmacology · doi:10.1038/npp.1993.46 · Cited by 128 · see citing works

Children at Risk for Schizophrenia: The Jerusalem Infant Development Study

Marcus, J. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820220053006 · Cited by 128 · see citing works

Increased density of microtubule associated protein 2-immunoreactive neurons in the prefrontal white matter of schizophrenic subjects

Anderson, S. A., Volk, D. W., & Lewis, D. A. (1996) · Schizophrenia Research · doi:10.1016/0920-9964(96)88521-5 · Cited by 123 · see citing works

Search for schizophrenia susceptibility genes

Pulver, A. E. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00281-4 · Cited by 121 · see citing works

EGFRs mediate chemotactic migration in the developing telencephalon

Carić, D., Raphael, H. E., Viti, J., Feathers, A., Wancio, D., & Lillien, L. E. (2001) · Development · doi:10.1242/dev.128.21.4203 · Cited by 121 · see citing works

Obstetric complications and schizophrenia: prenatal underdevelopment and subsequent neurodevelopmental impairment

Kunugi, H., Nanko, S., & Murray, R. M. (2001) · The British Journal of Psychiatry · doi:10.1192/bjp.178.40.s25 · Cited by 120 · see citing works

Prenatal Exposure to the 1957 Influenza Epidemic and Adult Schizophrenia: A Follow-Up Study

Cannon, M. D., Cotter, D., Coffey, V. P., Sham, P. C., Takei, N., Larkin, C., Murray, R. M., & O’Callaghan, E. (1996) · The British Journal of Psychiatry · doi:10.1192/bjp.168.3.368 · Cited by 116 · see citing works

A qualitative and quantitative analysis of the entorhinal cortex in schizophrenia

Krimer, L. S. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.8.732 · Cited by 111 · see citing works

Mutation of theEmx-1Homeobox Gene Disrupts the Corpus Callosum

Qiu, M. S., Anderson, S. A., Chen, S., Meneses, J. J., Hevner, R. F., Kuwana, E., Pedersen, R. A., & Rubenstein, J. L. R. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0207 · Cited by 104 · see citing works

Segregation analysis of schizophrenia and related disorders.

RISCH, N. J., & Baron, M. (1984) · PubMed · Cited by 100 · see citing works

Influenza epidemics and incidence of schizophrenia, affective disorders and mental retardation in Western Australia: no evidence of a major effect

Morgan, V. A., Castle, D. J., Page, A. C., Fazio, S., Gurrin, L. C., Burton, P. R., Montgomery, P., & Jablensky, A. V. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(97)00033-9 · Cited by 98 · see citing works

Prenatal Exposure to Influenza as a Cause of Schizophrenia

Crow, T. J. (1994) · The British Journal of Psychiatry · doi:10.1192/bjp.164.5.588 · Cited by 94 · see citing works

Cytoarchitecture of the entorhinal cortex in schizophrenia

Akil, M., & Lewis, D. A. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.7.1010 · Cited by 93 · see citing works

Childhood behavioral characteristics and adult brain morphology in schizophrenia

Walker, E. F., Lewine, R. R. J., & Neumann, C. S. (1996) · Schizophrenia Research · doi:10.1016/s0920-9964(96)00070-9 · Cited by 91 · see citing works

Minor Physical Anomalies and Schizophrenia Spectrum Disorders: A Prospective Investigation

Schiffman, J. E., Ekstrøm, M., LaBrie, J. W., D, F. S. M., Sørensen, H. J., & Mednick, S. A. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.2.238 · Cited by 85 · see citing works

Mapping of Quantitative Trait Loci with Knockout/Congenic StrainsPreprint

Bolivar, V. J., Cook, M. N., & Flaherty, L. A. (2001) · Genome Research · doi:10.1101/gr.194001 · Cited by 80 · see citing works

Regulation of regional differences in the differentiation of cerebral cortical neurons by EGF family-matrix interactions

Ferri, R. T., & Levitt, P. R. (1995) · Development · doi:10.1242/dev.121.4.1151 · Cited by 78 · see citing works

On the nature and mechanisms of obstetric influences in schizophrenia: a review and synthesis of epidemiologic studies

Cannon, T. D. (1997) · International Review of Psychiatry · doi:10.1080/09540269775259 · Cited by 72 · see citing works

Catching up on schizophrenia: natural history and neurobiology.

Lewis, D. A., & Lieberman, J. A. (2000) · Neuron · doi:10.1016/s0896-6273(00)00111-2 · Cited by 71 · see citing works

Behavioral changes in rats with early ventral hippocampal damage vary with age at damage

Wood, G. K., Lipska, B. K., & Weinberger, D. R. (1997) · Developmental Brain Research · doi:10.1016/s0165-3806(97)00050-3 · Cited by 69 · see citing works

The New York high-risk project: social and general intelligence in children at risk for schizophrenia

Ott, S. L., Spinelli, S., Rock, D., Roberts, S. A., Amminger, G. P., & Erlenmeyer‐Kimling, L. (1998) · Schizophrenia Research · doi:10.1016/s0920-9964(98)00010-3 · Cited by 67 · see citing works

Striatal TGF-α: postnatal developmental expression and evidence for a role in the proliferation of subependymal cells

Weickert, C. S., & Blum, M. (1995) · Developmental Brain Research · doi:10.1016/0165-3806(95)00026-a · Cited by 67 · see citing works

Is There a Neuropathology of Schizophrenia? Recent Findings Converge on Altered Thalamic-Prefrontal Cortical Connectivity

Lewis, D. A. (2000) · The Neuroscientist · doi:10.1177/107385840000600311 · Cited by 58 · see citing works

Quantitative Genetics and Mouse Behavior

Wehner, J. M., Radcliffe, R. A., & Bowers, B. J. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.845 · Cited by 58 · see citing works

Does Influenza Cause Schizophrenia? A Five Year Review

McGrath, J. J., & Castle, D. J. (1995) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048679509075888 · Cited by 55 · see citing works

The Neurodevelopmental Theory of Schizophrenia: Evidence Concerning Structure and Neuropsychology

Chua, S. E., & Murray, R. M. (1996) · Annals of Medicine · doi:10.3109/07853899608999119 · Cited by 55 · see citing works

Variability in the Human Entorhinal Region May Confound Neuropsychiatric Diagnoses

Heinsen, H., Gössmann, E., Rüb, U., Eisenmenger, W., Bauer, M. A., Ulmar, G., Bethke, B., Schüler, M., Schmitt, H.-P., Götz, M., et al. (1996) · Cells Tissues Organs · doi:10.1159/000147885 · Cited by 47 · see citing works

LIS1: from cortical malformation to essential protein of cellular dynamics

Leventer, R. J., Cardoso, C., Ledbetter, D. H., & Dobyns, W. B. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01887-7 · Cited by 44 · see citing works

Prenatal exposure to influenza and schizophrenia in surinamese and Dutch Antillean immigrants to The Netherlands

Selten, J., Slaets, J. P. J., & Kahn, R. S. (1998) · Schizophrenia Research · doi:10.1016/s0920-9964(97)00105-9 · Cited by 40 · see citing works

Epigenetic and Genotype-specific Effects on the Stability ofde Novo Imposed Methylation Patterns in Transgenic Mice

Schumacher, A., Koetsier, P. A., Hertz, J., & Doerfler, W. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004839200 · Cited by 39 · see citing works

Genes and subtypes of schizophrenia

Mirnics, K., & Lewis, D. A. (2001) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(01)02067-6 · Cited by 38 · see citing works

Is there a neuropathology of schizophrenia?

Stevens, J. R., & Casanova, M. F. (1988) · Biological Psychiatry · doi:10.1016/0006-3223(88)90268-5 · Cited by 35 · see citing works

Utility of the predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men aged 65 to 84 years is dependent on context defined by Apo E genotype and area of residence

Stengård, J., Kardia, S. L. R., Tervahauta, M., Ehnholm, C., Nissinen, A. M., & Sing, C. F. (1999) · Clinical Genetics · doi:10.1034/j.1399-0004.1999.560505.x · Cited by 30 · see citing works

Maternal exposure to influenza and paranoid schizophrenia

Grech, A., Takei, N., & Murray, R. M. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(97)00056-x · Cited by 24 · see citing works

Postnatal decrease in transforming growth factor alpha is associated with enlarged ventricles, deficient amygdaloid vasculature and performance deficits.

Burrows, R. C., Levitt, P., & Shors, T. J. (2000) · Neuroscience · doi:10.1016/s0306-4522(99)00558-8 · Cited by 22 · see citing works

Gliosis and its Implications for the Disease Process

Roberts, G. W., & Harrison, P. J. (2000) · doi:10.1093/oso/9780192629074.003.0006 · Cited by 17 · see citing works

Age-Related Changes in Frontal and Temporal Lobe Volumes in Men: A Magnetic Resonance Imaging Study

Bartzokis, G., Beckson, M., Lu, P. H., Nuechterlein, K. H., Edwards, N., & Mintz, J. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.5.461 · Cited by 14 · see citing works

From Spontaneous to Induced Neurological Mutations: A Personal Witness of the Ascent of the Mouse Model

RAKIC, P. T. (2000) · Results and problems in cell differentiation · doi:10.1007/978-3-540-48002-0_1 · Cited by 5 · see citing works

Twin studies of schizophrenia: From bow-and-arrow concordances to Star Wars Mx and functional genomics

Cardno, A. G., & Gottesman, I. I. (2000) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(200021)97:1

The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions

Gottesman, I. I., & Gould, T. D. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.4.636 · Cited by 5,615 · see citing works

Schizophrenia as a Complex Trait: Evidence From a Meta-analysis of Twin Studies

Sullivan, P. F., Kendler, K. S., & Neale, M. C. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.12.1187 · Cited by 2,356 · see citing works

Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms

Citri, A., & Malenka, R. C. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301559 · Cited by 2,323 · see citing works

Cortical inhibitory neurons and schizophrenia

Lewis, D. A., Hashimoto, T., & Volk, D. W. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1648 · Cited by 2,297 · see citing works

Spatio-temporal transcriptome of the human brain

Kang, H. J., Kawasawa, Y. I., Cheng, F., Zhu, Y., Xu, X., Li, M., Sousa, A. M. M., Pletikos, M., Meyer, K. A., Sedmak, G., et al. (2011) · Nature · doi:10.1038/nature10523 · Cited by 2,084 · see citing works

Abnormal neural oscillations and synchrony in schizophrenia

Uhlhaas, P. J., & Singer, W. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2774 · Cited by 2,120 · see citing works

Untitled work

(2009)

Rethinking schizophrenia

Insel, T. R. (2010) · Nature · doi:10.1038/nature09552 · Cited by 1,783 · see citing works

Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

Smith, S. E. P., Li, J., Garbett, K., Mirnics, K., & Patterson, P. H. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2178-07.2007 · Cited by 1,605 · see citing works

Evolution of the neocortex: a perspective from developmental biology

Rakic, P. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2719 · Cited by 1,565 · see citing works

A Handbook for the Study of Mental Health Second Edition

Scheid, T. L., & Brown, T. N. (2009) · Cited by 1,320 · see citing works

Interneuron dysfunction in psychiatric disorders

Marín, O. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3155 · Cited by 1,190 · see citing works

A Structural MRI Study of Human Brain Development from Birth to 2 Years

Knickmeyer, R. C., Gouttard, S., Kang, C., Evans, D., Wilber, K., Smith, J. K., Hamer, R. M., Lin, W., Gerig, G., & Gilmore, J. H. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.3479-08.2008 · Cited by 1,151 · see citing works

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

Mei, L., & Xiong, W.-C. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2392 · Cited by 1,030 · see citing works

Continuities and discontinuities in psychopathology between childhood and adult life

Rutter, M., Kim‐Cohen, J., & Maughan, B. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01614.x · Cited by 824 · see citing works

Animal models of schizophrenia

Jones, C., Watson, D., & Fone, K. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01386.x · Cited by 771 · see citing works

Sialic Acids in the Brain: Gangliosides and Polysialic Acid in Nervous System Development, Stability, Disease, and Regeneration

Schnaar, R. L., Gerardy-Schahn, R., & Hildebrandt, H. (2014) · Physiological Reviews · doi:10.1152/physrev.00033.2013 · Cited by 745 · see citing works

Reelin and brain development

Tissir, F., & Goffinet, A. M. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1113 · Cited by 748 · see citing works

The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications

Harrison, P. (2004) · Psychopharmacology · doi:10.1007/s00213-003-1761-y · Cited by 693 · see citing works

An integrated theory of sexual offending

Ward, T., & Beech, A. (2006) · Aggression and Violent Behavior · doi:10.1016/j.avb.2005.05.002 · Cited by 682 · see citing works

The environment and susceptibility to schizophrenia

Brown, A. S. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.09.003 · Cited by 664 · see citing works

BDNF signaling in context: From synaptic regulation to psychiatric disorders

Wang, C. S., Kavalali, E. T., & Monteggia, L. M. (2021) · Cell · doi:10.1016/j.cell.2021.12.003 · Cited by 629 · see citing works

Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action

Coster, S. D., & Larebeke, N. V. (2012) · Journal of Environmental and Public Health · doi:10.1155/2012/713696 · Cited by 622 · see citing works

Disrupted-In-Schizophrenia 1 Regulates Integration of Newly Generated Neurons in the Adult Brain

Duan, X., Chang, J. H., Ge, S., Faulkner, R. L., Kim, J. Y., Kitabatake, Y., Liu, X.-B., Yang, C.-H., Jordan, J. D., Ma, D. K., et al. (2007) · Cell · doi:10.1016/j.cell.2007.07.010 · Cited by 538 · see citing works

Genes for schizophrenia? Recent findings and their pathophysiological implications

Harrison, P. J., & Owen, M. J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12379-3 · Cited by 597 · see citing works

Dendritic spine pathology in schizophrenia

Glausier, J. R., & Lewis, D. A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2012.04.044 · Cited by 581 · see citing works

Cortical Evolution: Judge the Brain by Its Cover

Geschwind, D. H., & Rakic, P. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.045 · Cited by 519 · see citing works

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

Kamiya, A., Kubo, K., Tomoda, T., Takaki, M., Youn, R., Ozeki, Y., Sawamura, N., Park, U., Kudo, C., Okawa, M., et al. (2005) · Nature Cell Biology · doi:10.1038/ncb1328 · Cited by 531 · see citing works

Gender and Mental Health

Rosenfield, S., & Mouzon, D. M. (2012) · Handbooks of sociology and social research · doi:10.1007/978-94-007-4276-5_14 · Cited by 553 · see citing works

From dopamine to salience to psychosis—Linking biology, pharmacology and phenomenology of psychosis

Kapur, S., Mizrahi, R., & Li, M. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.01.003 · Cited by 512 · see citing works

Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia

Hashimoto, T., Arion, D., Unger, T., Maldonado-Avilés, J. G., Morris, H. M., Volk, D. W., Mirnics, K., & Lewis, D. A. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002011 · Cited by 490 · see citing works

Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling

Fazzari, P., Paternain, A. V., Valiente, M., Pla, R., Luján, R., Lloyd, K., Lerma, J., Marín, O., & Rico, B. (2010) · Nature · doi:10.1038/nature08928 · Cited by 501 · see citing works

Genetic insights into the neurodevelopmental origins of schizophrenia

Birnbaum, R., & Weinberger, D. R. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.125 · Cited by 493 · see citing works

Oxidative stress in schizophrenia: An integrated approach

Bitanihirwe, B. K. Y., & Woo, T.-U. W. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.008 · Cited by 474 · see citing works

Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1

Flames, N., Long, J. E., Garratt, A. N., Fischer, T. M., Gassmann, M., Birchmeier, C., Lai, C., Rubenstein, J. L. R., & Marı́n, O. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.028 · Cited by 431 · see citing works

Systematic meta-review and quality assessment of the structural brain alterations in schizophrenia

Shepherd, A. M., Laurens, K. R., Matheson, S. L., Carr, V. J., & Green, M. J. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.12.015 · Cited by 412 · see citing works

Cognitive Dysfunction in Schizophrenia: Convergence of γ-Aminobutyric Acid and Glutamate Alterations

Lewis, D. A., & Moghaddam, B. (2006) · Archives of Neurology · doi:10.1001/archneur.63.10.1372 · Cited by 404 · see citing works

Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

Clay, H. B., Daws, S., & Konradi, C. (2011) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2010.08.007 · Cited by 399 · see citing works

Redox dysregulation, neurodevelopment, and schizophrenia

Do, K. Q., Cabungcal, J. H., Frank, A., Steullet, P., & Cuenod, M. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.05.001 · Cited by 384 · see citing works

Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping

Deoni, S. C. L., Dean, D. C., O'Muircheartaigh, J., Dirks, H., & Jerskey, B. A. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.07.037 · Cited by 390 · see citing works

Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia

Corfas, G., Roy, K., & Buxbaum, J. D. (2004) · Nature Neuroscience · doi:10.1038/nn1258 · Cited by 388 · see citing works

Functions of Nogo proteins and their receptors in the nervous system

Schwab, M. E. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2936 · Cited by 378 · see citing works

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

Camargo, L. M., Collura, V, Rain, J.-C., Mizuguchi, K., Hermjakob, H., Kerrien, S., Bonnert, T. P., Whiting, P. J., & Brandon, N. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001880 · Cited by 405 · see citing works

Sculpting Neural Circuits by Axon and Dendrite Pruning

Riccomagno, M. M., & Kolodkin, A. L. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013038 · Cited by 366 · see citing works

Epidemiology-driven neurodevelopmental animal models of schizophrenia

Meyer, U., & Feldon, J. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.10.018 · Cited by 366 · see citing works

Neuroplasticity of Neocortical Circuits in Schizophrenia

Lewis, D. A., & González‐Burgos, G. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301563 · Cited by 362 · see citing works

A Neurobehavioral Systems Analysis of Adult Rats Exposed to Methylazoxymethanol Acetate on E17: Implications for the Neuropathology of Schizophrenia

Moore, H. M., Jentsch, J. D., Ghajarnia, M., Geyer, M. A., & Grace, A. A. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.01.003 · Cited by 359 · see citing works

Neuronal avalanches organize as nested theta- and beta/gamma-oscillations during development of cortical layer 2/3

Gireesh, E. D., & Plenz, D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800537105 · Cited by 328 · see citing works

Serotonin and brain development

Sodhi, M., & Sanders‐Bush, E. (2004) · International review of neurobiology · doi:10.1016/s0074-7742(04)59006-2 · Cited by 337 · see citing works

Regulation of neocortical interneuron development and the implications for neurodevelopmental disorders

Levitt, P. R., Eagleson, K. L., & Powell, E. M. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.05.008 · Cited by 331 · see citing works

Hippocampal-Prefrontal Interactions in Cognition, Behavior and Psychiatric Disease

Sigurdsson, T., & Duvarci, S. (2016) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2015.00190 · Cited by 309 · see citing works

Molecular Evidence for Increased Expression of Genes Related to Immune and Chaperone Function in the Prefrontal Cortex in Schizophrenia

Arion, D., Unger, T. L., Lewis, D. A., Levitt, P. R., & Mirnics, K. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.021 · Cited by 328 · see citing works

Pathophysiologically based treatment interventions in schizophrenia

Lewis, D. A., & González‐Burgos, G. (2006) · Nature Medicine · doi:10.1038/nm1478 · Cited by 320 · see citing works

Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1–ErbB4 and DISC1

Jaaro-Peled, H., Hayashi‐Takagi, A., Seshadri, S., Kamiya, A., Brandon, N. J., & Sawa, A. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.05.007 · Cited by 315 · see citing works

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

Miyoshi, K., Honda, A., Baba, K., Taniguchi, M., Oono, K., Fujita, T., Kuroda, S., Katayama, T., & Tohyama, M. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001352 · Cited by 314 · see citing works

Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

Gysin, R., Kraftsik, R., Sandell, J., Bovet, P., Chappuis, C., Conus, P., Deppen, P., Preisig, M., Ruiz, V., Steullet, P., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706778104 · Cited by 309 · see citing works

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

Miller, B. H., Zeier, Z., Xi, L., Lanz, T. A., Deng, S., Strathmann, J., Willoughby, D., Kenny, P. J., Elsworth, J. D., Lawrence, M. S., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113793109 · Cited by 309 · see citing works

Language in Schizophrenia Part 1: An Introduction

Kuperberg, G. R. (2010) · Language and Linguistics Compass · doi:10.1111/j.1749-818x.2010.00216.x · Cited by 306 · see citing works

Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders

García-Gutiérrez, M. S., Navarrete, F., Gasparyan, A., Austrich-Olivares, A., Sala, F., & Manzanares, J. (2020) · Biomolecules · doi:10.3390/biom10111575 · Cited by 306 · see citing works

Labeling and Stigma

Link, B. G., & Phelan, J. C. (2012) · Handbooks of sociology and social research · doi:10.1007/978-94-007-4276-5_25 · Cited by 304 · see citing works

Developmental neuroinflammation and schizophrenia

Meyer, U. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.11.003 · Cited by 300 · see citing works

Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits

Niwa, M., Kamiya, A., Murai, R., Kubo, K., Gruber, A. J., Tomita, K., Lu, L., Tomisato, S., Jaaro-Peled, H., Seshadri, S., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.019 · Cited by 291 · see citing works

The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders

van der Stelt, M., & Marzo, V. D. (2003) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2003.08.101 · Cited by 286 · see citing works

Theories of schizophrenia: a genetic-inflammatory-vascular synthesis

Hanson, D. R., & Gottesman, I. I. (2005) · BMC Medical Genetics · doi:10.1186/1471-2350-6-7 · Cited by 274 · see citing works

Prenatal stress: Role in psychotic and depressive diseases

Markham, J. A., & Koenig, J. I. (2010) · Psychopharmacology · doi:10.1007/s00213-010-2035-0 · Cited by 274 · see citing works

Development, evolution and pathology of neocortical subplate neurons

Hoerder‐Suabedissen, A., & Molnár, Z. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn3915 · Cited by 269 · see citing works

Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures

Osimo, E. F., Beck, K., Marques, T. R., & Howes, O. D. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0041-5 · Cited by 264 · see citing works

Phencyclidine animal models of schizophrenia: Approaches from abnormality of glutamatergic neurotransmission and neurodevelopment

Mouri, A., Noda, Y., Enomoto, T., & Nabeshima, T. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.06.019 · Cited by 267 · see citing works

Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietin

Ehrenreich, H., Hinze‐Selch, D., Stawicki, S., Aust, C., Knolle-Veentjer, S., Wilms, S., Heinz, G., Erdag, S., Jahn, H., Degner, D., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001907 · Cited by 260 · see citing works

Schizophrenia-Related Neural and Behavioral Phenotypes in Transgenic Mice Expressing TruncatedDisc1

Shen, S., Lang, B., Nakamoto, C., Zhang, F., Pu, J., Kuan, S. L., Chatzi, C. A., He, S., Mackie, I., Brandon, N. J., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3299-08.2008 · Cited by 250 · see citing works

To poly(I:C) or not to poly(I:C): Advancing preclinical schizophrenia research through the use of prenatal immune activation models

Meyer, U., & Feldon, J. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.01.009 · Cited by 247 · see citing works

Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice

Matrisciano, F., Tueting, P., Dalal, I., Kadriu, B., Grayson, D. R., Davis, J. M., Nicoletti, F., & Guidotti, A. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.04.013 · Cited by 271 · see citing works

GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia

González‐Burgos, G., Fish, K. N., & Lewis, D. A. (2011) · Neural Plasticity · doi:10.1155/2011/723184 · Cited by 244 · see citing works

Neural development of the neuregulin receptor ErbB4 in the cerebral cortex and the hippocampus: preferential expression by interneurons tangentially migrating from the ganglionic eminences

Yau, H.-J. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.3.252 · Cited by 225 · see citing works

Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models

Malone, D. T., Hill, M. N., & Rubino, T. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.00721.x · Cited by 237 · see citing works

The Cells of Cajal-Retzius: Still a Mystery One Century After

Soriano, E., & del Rı́o, J. A. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.019 · Cited by 237 · see citing works

Neurodevelopment, GABA System Dysfunction, and Schizophrenia

Schmidt, M. J., & Mirnics, K. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.95 · Cited by 239 · see citing works

Neurodevelopmental and neurodegenerative models of schizophrenia: white matter at the center stage

Kochunov, P., & Hong, L. E. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu070 · Cited by 236 · see citing works

Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies

Lewis, D. A., & Sweet, R. A. (2009) · Journal of Clinical Investigation · doi:10.1172/jci37335 · Cited by 235 · see citing works

Prenatal stress generates deficits in rat social behavior: Reversal by oxytocin

Lee, P. R., Brady, D. L., Shapiro, R. A., Dorsa, D. M., & Koenig, J. I. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.042 · Cited by 270 · see citing works

Early-Life Insults Impair Parvalbumin Interneurons via Oxidative Stress: Reversal by N-Acetylcysteine

Cabungcal, J.-H., Steullet, P., Kraftsik, R., Cuenod, M., & Do, K. Q. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.09.020 · Cited by 232 · see citing works

Effects of prenatal infection on prepulse inhibition in the rat depend on the nature of the infectious agent and the stage of pregnancy

Fortier, M., Luheshi, G. N., & Boksa, P. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.04.016 · Cited by 229 · see citing works

White matter integrity and prediction of social and role functioning in subjects at ultra-high risk for psychosis

Karlsgodt, K. H., Niendam, T. A., Bearden, C. E., & Cannon, T. D. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.03.013 · Cited by 229 · see citing works

Antibodies to infectious agents in individuals with recent onset schizophrenia

Leweke, F. M., Gerth, C. W., Koethe, D., Klosterk�tter, J., Ruslanova, I., Krivogorsky, B., Torrey, E. F., & Yolken, R. H. (2004) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-004-0481-6 · Cited by 228 · see citing works

The functional neuroanatomy of symptom dimensions in schizophrenia: A qualitative and quantitative review of a persistent question

Goghari, V. M., Sponheim, S. R., & MacDonald, A. W. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.09.004 · Cited by 224 · see citing works

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

Brandon, N. J., Handford, E. J., Schurov, I., Rain, J., Pelling, M., Duran-Jimenez, B., Camargo, L. M., Oliver, K. R., Beher, D., Shearman, M. S., et al. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2003.09.009 · Cited by 224 · see citing works

The Poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery

Reisinger, S. N., Khan, D., Kong, E., Berger, A., Pollak, A. J., & Pollak, D. D. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2015.01.001 · Cited by 219 · see citing works

Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: A gene ontology study

Katsel, P., Davis, K. L., & HAROUTUNIAN, V. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.06.007 · Cited by 223 · see citing works

N-Methyl-d-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives

Millan, M. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2199-1 · Cited by 226 · see citing works

DISC1 Regulates the Transport of the NUDEL/LIS1/14-3-3ε Complex through Kinesin-1

Taya, S., Shinoda, T., Tsuboi, D., Uraguchi‐Asaki, J., Nagai, K., Hikita, T., Kuroda, S., Kuroda, K., Shimizu, M., Hirotsune, S., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3826-06.2006 · Cited by 222 · see citing works

Developmental origins of brain disorders: roles for dopamine

Money, K. M., & Stanwood, G. D. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00260 · Cited by 221 · see citing works

Toward a developmental neurobiology of autism

Polleux, F., & Lauder, J. M. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20044 · Cited by 216 · see citing works

Alterations in dendritic morphology of prefrontal cortical and nucleus accumbens neurons in post-pubertal rats after neonatal excitotoxic lesions of the ventral hippocampus

Flores, G., Alquicer, G., Gómez, A. B. S., Zaldivar, G. A., Stewart, J., Quirion, R., & Srivastava, L. K. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.02.021 · Cited by 220 · see citing works

Neuregulin 1 Promotes Excitatory Synapse Development and Function in GABAergic Interneurons

Ting, A. K. L., Chen, Y., Wen, L., Yin, D., Shen, C., Tao, Y., Liu, X., Xiong, W., & Mei, L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2538-10.2011 · Cited by 216 · see citing works

Synaptic Plasticity Shapes Brain Connectivity: Implications for Network Topology

Bassi, M. S., Iezzi, E., Gilio, L., Centonze, D., & Buttari, F. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20246193 · Cited by 209 · see citing works

Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal Cortex: Intrinsic Properties and Synaptic Function

Zhang, Z. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00855.2003 · Cited by 210 · see citing works

Excitation control: balancing PSD-95 function at the synapse

Keith, D. J. (2008) · Frontiers in Molecular Neuroscience · doi:10.3389/neuro.02.004.2008 · Cited by 206 · see citing works

Interplay between DISC1 and GABA Signaling Regulates Neurogenesis in Mice and Risk for Schizophrenia

Kim, J., Liu, C. Y., Zhang, F., Duan, X., Wen, Z., Song, J., Feighery, E. L., Lu, B., Rujescu, D., Clair, D. S., et al. (2012) · Cell · doi:10.1016/j.cell.2011.12.037 · Cited by 207 · see citing works

Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis

Eastwood, S. L., & Harrison, P. J. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001399 · Cited by 208 · see citing works

Erythropoietin: a candidate compound for neuroprotection in schizophrenia

Ehrenreich, H., Degner, D., Meller, J., Brines, M. L., Béhé, M. P., Hasselblatt, M., Woldt, H., Falkai, P., Knerlich‐Lukoschus, F., Jacob, S., et al. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001442 · Cited by 209 · see citing works

Schizophrenia: A Critical Review of the Developmental Hypothesis

Lewis, D. S. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142818

Neurodevelopmental Pathogenesis of Schizophrenia

Nasrallah, H. A. (1993) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(18)30173-4 · Cited by 64 · see citing works

Molecular Genetic Study of Schizophrenia Based on Neurodevelopmental Hypothesis

Ikeda, M., Taya, S., Kaibuchi, K., Iwata, N., & Ozaki, N. (2007) · CRC Press eBooks · doi:10.3109/9781420019544-8

Future of Days Past: Neurodevelopment and Schizophrenia

Weinberger, D. R. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx118 · Cited by 115 · see citing works

Schizophrenia: A Neurodevelopmental Perspective

Pilowsky, L. S., Kerwin, R. W., & Murray, R. M. (1993) · Neuropsychopharmacology · doi:10.1038/npp.1993.46 · Cited by 128 · see citing works