Thalamocortical Oscillations: Local Control of EEG Slow Waves
Abstract
This article starts with a brief review of the thalamocortical system architecture, which is composed of the projecting thalamic nuclei, the thalamic reticular nucleus, and the neocortex. Then we provide a description of the three states of vigilances followed by a detailed review of major brain rhythms present in the thalamocortical system, ranging from very slow to very fast oscillations. We provide descriptions of known mechanisms and hypotheses for unknown mechanisms for the generation of the different rhythms. The last part offers a detailed review on sleep slow oscillation describing its properties in the thalamocortical system, proposing a mechanism of generation of active states and a description of their propagation. Keywords: Slow-wave sleep, Slow oscillation, sleep, thalamocortical, states of vigilance, thalamocortical system architecture, projecting thalamic nuclei, hypotheses, vast majority of fibers, giant synapses, glutamatergic axons, thalamic nucleus, corticothalamic axons, electrotonically RE neurons, cortical layers, intrinsically-bursting neurons
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The slow oscillation of the intact brain likely reflects an interaction between cortical and thalamic networks.
“Nevertheless, the slow oscillation of the intact brain likely reflects an interaction between cortical and thalamic networks (239, 1196).”
From About Sleep's Role in Memory (2013) · cites this paper as [1196]
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Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783 · see citing works
Ito, J., Roy, S., Liu, Y., Cao, Y., Fletcher, M., Lu, L., Boughter, J. D., Grün, S., & Heck, D. H. (2014) · Nature Communications · doi:10.1038/ncomms4572 · Cited by 252 · see citing works
- Authors
- Timofeev, I., & Chauvette, S.
- Affiliations
- Université Laval (CA)
- Venue
- Current Topics in Medicinal Chemistry
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2011-09-01
- Volume
- 11
- Issue
- 19
- Pages
- 2457-2471
- ISSN
- 1568-0266 (ISSN-L)
- OpenAlex
- W2333303354
- Cited by
- 55
- References
- 173
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 2 · 2021: 3 · 2020: 3 · 2019: 7 · 2018: 3 · 2017: 4 · 2016: 3 · 2015: 8 · 2014: 5 · 2013: 8 · 2012: 1
- FWCI
- 2.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Topics in Medicinal Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Corpus Université Laval (Université Laval) (submittedVersion)
- Funders
- National Institutes of Health (5r01ns060870-04)
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada
- National Institute of Neurological Disorders and Stroke (R01-NS-060870)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- thalamocortical system, EEG slow waves, slow oscillations, sleep, thalamic reticular nucleus, corticothalamic projections, slow-wave sleep, active state, oscillation propagation, giant synapse
- MeSH terms
- Animals, Electroencephalography, Humans, Thalamus
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