Coherent 40-Hz oscillation characterizes dream state in humans.

Llinás, R; Ribary, U

doi:10.1073/pnas.90.5.2078

Cited by 962Neural dynamics and brain functionSleep and Wakefulness ResearchCreativity in Education and Neuroscience

Coherent 40-Hz oscillation characterizes dream state in humans.

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Llinás, R, Ribary, U·1993·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.90.5.2078PMC PMC46024

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Abstract

Magnetic recording from five normal human adults demonstrates large 40-Hz coherent magnetic activity in the awake and in rapid-eye-movement (REM) sleep states that is very reduced during delta sleep (deep sleep characterized by delta waves in the electroencephalogram). This 40-Hz magnetic oscillation has been shown to be reset by sensory stimuli in the awake state. Such resetting is not observed during REM or delta sleep. The 40 Hz in REM sleep is characterized, as is that in the awake state, by a fronto-occipital phase shift over the head. This phase shift has a maximum duration of approximately 12-13 msec. Because 40-Hz oscillation is seen in wakefulness and in dreaming, we propose it to be a correlate of cognition, probably resultant from coherent 40-Hz resonance between thalamocortical-specific and nonspecific loops. Moreover, we proposed that the specific loops give the content of cognition, and a nonspecific loop gives the temporal binding required for the unity of cognitive experience.

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REM-locked activation overlaps with brain regions expressing or modulating gamma oscillations: the thalamocortical sensory system, mesopontine tegmentum, and basal forebrain.
“REM-locked activation overlaps with brain regions expressing or modulating gamma oscillations (Gross and Gotman, 1999; Jouny et al., 2000); i.e., the thalamocortical sensory system (Llinas and Ribary, 1993), mesopontine tegmentum (Steriade et al., 1991) and basal forebrain (Szymusiak, 1995; Mesulam, 2004; Perry and Perry, 2004).”
From Virtual reality and consciousness inference in dreaming (2014) · cites this paper as Llinas and Ribary, 1993

Electroencephalography—Basic principles, clinical applications and related fields
(1982) · Journal of the Autonomic Nervous System · doi:10.1016/0165-1838(82)90067-4 · Cited by 3,449 · see citing works
Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex
Gray, C. M., & Singer, W. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.5.1698 · Cited by 2,463 · see citing works
Coherent oscillations: A mechanism of feature linking in the visual cortex?
Eckhorn, R., Bauer, R., Jordan, W., Brosch, M., Kruse, W., Munk, M., & Reitboeck, H. J. (1988) · Biological Cybernetics · doi:10.1007/bf00202899 · Cited by 2,329 · see citing works
A 40-Hz auditory potential recorded from the human scalp.
Galambos, R., Makeig, S., & Talmachoff, P. J. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.4.2643 · Cited by 1,257 · see citing works
Of dreaming and wakefulness
Llinás, R. R., & Paré, D. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90075-y · Cited by 641 · see citing works
Self-citation
In vitro neurons in mammalian cortical layer 4 exhibit intrinsic oscillatory activity in the 10- to 50-Hz frequency range.
Llinás, R. R., Grace, A. A., & Yarom, Y. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.3.897 · Cited by 541 · see citing works
Self-citation
Magnetic field tomography of coherent thalamocortical 40-Hz oscillations in humans.
Ribary, U., Ioannides, A. A., Singh, K. D., Hasson, R., Bolton, J. P., Lado, F. A., Mogilner, A. Y., & Llinas, R. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.24.11037 · Cited by 541 · see citing works
Self-citation
Fast oscillations (20-40 Hz) in thalamocortical systems and their potentiation by mesopontine cholinergic nuclei in the cat.
Steriade, M., Dossi, R. C., Paré, D., & Oakson, G. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.10.4396 · Cited by 455 · see citing works
Frequency analysis of olfactory system EEG in cat, rabbit, and rat
Bressler, S. L., & Freeman, W. J. (1980) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(80)90319-3 · Cited by 382 · see citing works
Some Reflections on Visual AwarenessPreprint
Crick, F. H. C., & Koch, C. (1990) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1990.055.01.089 · Cited by 337 · see citing works
Magnetic localization of neuronal activity in the human brain.
Yamamoto, T., Williamson, S. J., Kaufman, L., Nicholson, C., & Llinas, R. H. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.22.8732 · Cited by 205 · see citing works
Oscillatory discharge in the visual system: does it have a functional role?
Ghose, G. M., & Freeman, R. D. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.68.5.1558 · Cited by 196 · see citing works
Anatomical localization of cortical beta rhythms in cat
Bouyer, J. J., Montaron, M., Vahnée, J. M., Albert, M. P., & Rougeul, A. (1987) · Neuroscience · doi:10.1016/0306-4522(87)92965-4 · Cited by 150 · see citing works
Voltage-dependent 40-Hz oscillations in rat reticular thalamic neurons in vivo
Pinault, D., & Deschênes, M. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90312-p · Cited by 149 · see citing works
Anatomical localization revealed by MEG recordings of the human somatosensory system
Suk, J., Ribary, U., Cappell, J., Yamamoto, T., & Llinas, R. H. (1991) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(91)90032-y · Cited by 114 · see citing works
Self-citation
Cerebral magnetic fields.
Hari, R., & Ilmoniemi, R. J. (1986) · PubMed · Cited by 109 · see citing works
Laminar and synaptic organization of the projection from the thalamic nucleus centralis to primary visual cortex in the cat
Cunningham, E. T., & LeVay, S. (1986) · The Journal of Comparative Neurology · doi:10.1002/cne.902540106 · Cited by 59 · see citing works
Quantal and Deterministic Timing in Human Duration Discrimination
Kristofferson, A. B. (1984) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1984.tb23413.x · Cited by 59 · see citing works
[Prolonged hypersomnia caused by bilateral lesions of the medial activator system; thrombotic syndrome of the bifurcation of the basilar trunk].
Façon, E., Steriade, M., & WERTHEIM, N. (1958) · PubMed · Cited by 42 · see citing works

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Neuronal Oscillations in Cortical Networks
Buzsáki, G., & Draguhn, A. (2004) · Science · doi:10.1126/science.1099745 · Cited by 6,576 · see citing works
Thalamocortical oscillations in the sleeping and aroused brain
Steriade, M., McCormick, D. A., & Sejnowski, T. J. (1993) · Science · doi:10.1126/science.8235588 · Cited by 3,564 · see citing works
A sensorimotor account of vision and visual consciousness
O'Regan, J. K., & Noë, A. (2001) · Behavioral and Brain Sciences · doi:10.1017/s0140525x01000115 · Cited by 3,126 · see citing works
Neuronal Synchrony: A Versatile Code for the Definition of Relations?
Singer, W. (1999) · Neuron · doi:10.1016/s0896-6273(00)80821-1 · Cited by 2,581 · see citing works
Oscillatory gamma activity in humans and its role in object representation
Tallon‐Baudry, C. (1999) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(99)01299-1 · Cited by 2,111 · see citing works
Neurophysiological and Computational Principles of Cortical Rhythms in Cognition
Wang, X.-J. (2010) · Physiological Reviews · doi:10.1152/physrev.00035.2008 · Cited by 1,939 · see citing works
The hyperarousal model of insomnia: A review of the concept and its evidence
Riemann, D., Spiegelhalder, K., Feige, B., Voderholzer, U., Berger, M., Perlis, M., & Nissen, C. (2010) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2009.04.002 · Cited by 1,789 · see citing works
Meditation states and traits: EEG, ERP, and neuroimaging studies.
Cahn, B. R., & Polich, J. (2006) · Psychological Bulletin · doi:10.1037/0033-2909.132.2.180 · Cited by 1,734 · see citing works
Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation
Whittington, M. A., Traub, R. D., & Jefferys, J. G. R. (1995) · Nature · doi:10.1038/373612a0 · Cited by 1,613 · see citing works
The theta-gamma neural code
Lisman, J. E., & Jensen, O. (2013) · Neuron · doi:10.1016/j.neuron.2013.03.007 · Cited by 1,609 · see citing works
Perception's shadow: long-distance synchronization of human brain activity
Rodriguez, E., George, N., Lachaux, J.-P., Martinerie, J., Renault, B., & Varela, F. J. (1999) · Nature · doi:10.1038/17120 · Cited by 1,915 · see citing works
Stimulus Specificity of Phase-Locked and Non-Phase-Locked 40 Hz Visual Responses in Human
Tallon‐Baudry, C., Bertrand, O., Delpuech, C., & Pernier, J. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-13-04240.1996 · Cited by 1,526 · see citing works
Gamma (40-100 Hz) oscillation in the hippocampus of the behaving rat
Bragin, A., Jando, G., Nadasdy, Z., Hetke, J., Wise, K., & Buzsaki, G. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00047.1995 · Cited by 1,527 · see citing works
Control of sleep and wakefulness
Brown, R. E., Basheer, R., McKenna, J. T., Strecker, R. E., & McCarley, R. W. (2012) · Physiological Reviews · doi:10.1152/physrev.00032.2011 · Cited by 1,477 · see citing works
Storage of 7 +/- 2 short-term memories in oscillatory subcycles
Lisman, J. E., & Idiart, M. A. P. (1995) · Science · doi:10.1126/science.7878473 · Cited by 1,471 · see citing works
The Significance of Free Will
Kane, R. (1999) · doi:10.1093/0195126564.001.0001 · Cited by 1,410 · see citing works
Thalamocortical dysrhythmia: A neurological and neuropsychiatric syndrome characterized by magnetoencephalography
Llinás, R. R., Ribary, U., Jeanmonod, D., Kronberg, E., & Mitra, P. P. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.15222 · Cited by 1,395 · see citing works
Self-citation
Temporal binding and the neural correlates of sensory awareness.
Engel, A. K., & Singer, W. (2001) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01568-0 · Cited by 1,372 · see citing works
Natural waking and sleep states: a view from inside neocortical neurons
Steriade, M., Timofeev, I., & Grenier, F. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.5.1969 · Cited by 1,296 · see citing works
Grouping of brain rhythms in corticothalamic systems
Steriade, M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.10.029 · Cited by 1,296 · see citing works
Blind separation of auditory event-related brain responses into independent components
Makeig, S., Jung, T., Bell, A. J., Ghahremani, D. G., & B, T. J. S. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.20.10979 · Cited by 1,211 · see citing works
Sleep-Dependent Learning and Memory Consolidation
Walker, M. P., & Stickgold, R. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.031 · Cited by 1,113 · see citing works
Overnight therapy? The role of sleep in emotional brain processing
Walker, M. P., & van der Helm, E. (2009) · Psychological Bulletin · doi:10.1037/a0016570 · Cited by 1,087 · see citing works
The functional significance of mu rhythms: Translating “seeing” and “hearing” into “doing”
Pineda, J. A. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.04.005 · Cited by 1,015 · see citing works
The Role of Sleep in Cognition and Emotion
Walker, M. P. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04416.x · Cited by 1,024 · see citing works
Oscillatory γ-Band (30–70 Hz) Activity Induced by a Visual Search Task in Humans
Tallon‐Baudry, C., Bertrand, O., Delpuech, C., & Pernier, J. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-02-00722.1997 · Cited by 926 · see citing works
Scaling Brain Size, Keeping Timing: Evolutionary Preservation of Brain Rhythms
Buzsáki, G., Logothetis, N., & Singer, W. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.002 · Cited by 886 · see citing works
Consciousness without a cerebral cortex: A challenge for neuroscience and medicine
Merker, B. (2007) · Behavioral and Brain Sciences · doi:10.1017/s0140525x07000891 · Cited by 868 · see citing works
The cognitive neuroscience of sleep: neuronal systems, consciousness and learning
Hobson, J. A., & Pace-Schott, E. F. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn915 · Cited by 835 · see citing works
Corticothalamic resonance, states of vigilance and mentation
Steriade, M. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00353-5 · Cited by 817 · see citing works
Coherence of gamma-band EEG activity as a basis for associative learning
Miltner, W. H. R., Braun, C., Arnold, M., Witte, H., & Taub, E. (1999) · Nature · doi:10.1038/17126 · Cited by 798 · see citing works
Sleep, learning, and dreams: off-line memory reprocessing
Stickgold, R., Hobson, J. A., Fosse, R., & Fosse, M. (2001) · Science · doi:10.1126/science.1063530 · Cited by 762 · see citing works
From the neuron doctrine to neural networks
Yuste, R. (2015) · Nature reviews. Neuroscience · doi:10.1038/nrn3962 · Cited by 748 · see citing works
The thalamic matrix and thalamocortical synchrony
Jones, E. G. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01922-6 · Cited by 688 · see citing works
Mental imagery: In search of a theory
Pylyshyn, Z. W. (2002) · Behavioral and Brain Sciences · doi:10.1017/s0140525x02000043 · Cited by 728 · see citing works
The regulation of sleep and arousal: development and psychopathology
Dahl, R. E. (1996) · Development and Psychopathology · doi:10.1017/s0954579400006945 · Cited by 707 · see citing works
Origin of Slow Cortical Oscillations in Deafferented Cortical Slabs
Timofeev, I. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.12.1185 · Cited by 710 · see citing works
The neuronal basis for consciousness
The American Association for Research into Nervous and Mental Diseases, Llinás, R., Ribary, U., Contreras, D., & Pedroarena, C. M. (1998) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1998.0336 · Cited by 710 · see citing works
Self-citation
Electrophysiological correlates of the brain's intrinsic large-scale functional architecture
He, B. J., Snyder, A. Z., Zempel, J. M., Smyth, M. D., & Raichle, M. E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807010105 · Cited by 670 · see citing works
Very Slow Activity Fluctuations in Monkey Visual Cortex: Implications for Functional Brain Imaging
Leopold, D. A. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.4.422 · Cited by 675 · see citing works
The thalamic reticular nucleus: structure, function and concept
Pinault, D. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.04.008 · Cited by 683 · see citing works
The reinterpretation of dreams: An evolutionary hypothesis of the function of dreaming
Revonsuo, A. (2000) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00004015 · Cited by 676 · see citing works
Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation
Steriade, M., Amzica, F., & Contreras, D. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-01-00392.1996 · Cited by 646 · see citing works
Synchrony Unbound
Shadlen, M. N., & Movshon, J. A. (1999) · Neuron · doi:10.1016/s0896-6273(00)80822-3 · Cited by 606 · see citing works
Human EEG gamma oscillations in neuropsychiatric disorders
Herrmann, C. S., & Demıralp, T. (2005) · Clinical Neurophysiology · doi:10.1016/j.clinph.2005.07.007 · Cited by 600 · see citing works
How the brain encodes the order of letters in a printed word: The SERIOL model and selective literature review
Whitney, C. (2001) · Psychonomic Bulletin & Review · doi:10.3758/bf03196158 · Cited by 447 · see citing works
Low-frequency (<1Hz) oscillations in the human sleep electroencephalogram
Achermann, P., & Borbély, A. A. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00186-3 · Cited by 577 · see citing works
Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states
Destexhe, A., Contreras, D., & Steriade, M. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-11-04595.1999 · Cited by 573 · see citing works
Human oscillatory brain activity near 40 Hz coexists with cognitive temporal binding.
Joliot, M., Ribary, U., & Llinas, R. H. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.24.11748 · Cited by 543 · see citing works
Self-citation
Neural Discharge and Local Field Potential Oscillations in Primate Motor Cortex During Voluntary Movements
Donoghue, J. P., Sanes, J. N., Hatsopoulos, N. G., & Gaál, G. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.1.159 · Cited by 538 · see citing works
High-frequency oscillations and seizure generation in neocortical epilepsy
Worrell, G. A., Parish, L. M., Cranstoun, S. D., Jonas, R., Baltuch, G. H., & Litt, B. (2004) · Brain · doi:10.1093/brain/awh149 · Cited by 537 · see citing works
Impact of Network Activities on Neuronal Properties in Corticothalamic Systems
Steriade, M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.1.1 · Cited by 530 · see citing works
Viewpoint: the core and matrix of thalamic organization
Jones, E. G. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00581-2 · Cited by 504 · see citing works
The What and Why of Binding
von der Malsburg, C. (1999) · Neuron · doi:10.1016/s0896-6273(00)80825-9 · Cited by 501 · see citing works
<i>Central Thalamic Contributions to Arousal Regulation and Neurological Disorders of Consciousness</i>
Schiff, N. D. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1417.029 · Cited by 463 · see citing works
Synchronous Gamma activity: a review and contribution to an integrative neuroscience model of schizophrenia
Lee, K.-H., Williams, L. M., Breakspear, M. J., & Gordon, E. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00220-5 · Cited by 479 · see citing works
A refined model of sleep and the time course of memory formation
Walker, M. P. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000026 · Cited by 466 · see citing works
Neuronal networks for induced ‘40 Hz’ rhythms
Jefferys, J. G. R., Traub, R. D., & Whittington, M. A. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10023-0 · Cited by 461 · see citing works
Why people see things that are not there: A novel Perception and Attention Deficit model for recurrent complex visual hallucinations
Collerton, D., Perry, E. K., & McKeith, I. G. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000130 · Cited by 437 · see citing works
The theta/gamma discrete phase code occuring during the hippocampal phase precession may be a more general brain coding scheme
Lisman, J. (2005) · Hippocampus · doi:10.1002/hipo.20121 · Cited by 435 · see citing works
A Neural Coding Scheme Formed by the Combined Function of Gamma and Theta Oscillations
Lisman, J. E., & Buzsáki, G. (2008) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn060 · Cited by 433 · see citing works
Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance [published erratum appears in Cereb Cortex 1997 Dec;7(8):779]
Steriade, M. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.6.583 · Cited by 429 · see citing works
The Temporal Correlation Hypothesis of Visual Feature Integration
Gray, C. M. (1999) · Neuron · doi:10.1016/s0896-6273(00)80820-x · Cited by 541 · see citing works
Synchronization and Oscillatory Dynamics in Heterogeneous, Mutually Inhibited Neurons
White, J. A., Chow, C. C., Rit, J., Soto-Treviño, C., & Kopell, N. (1998) · Journal of Computational Neuroscience · doi:10.1023/a:1008841325921 · Cited by 415 · see citing works
Toward a unified theory of narcosis: Brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness
Alkire, M. T., Haier, R. J., & Fallon, J. H. (2000) · Consciousness and Cognition · doi:10.1006/ccog.1999.0423 · Cited by 391 · see citing works
The Hebbian paradigm reintegrated: local reverberations as internal representations
Amit, D. J. (1995) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00040164 · Cited by 388 · see citing works
Auditory Processing across the Sleep-Wake Cycle
Portas, C. M., Krakow, K., Allen, P., Josephs, O., Armony, J. L., & Frith, C. D. (2000) · Neuron · doi:10.1016/s0896-6273(00)00169-0 · Cited by 392 · see citing works
The Role of Neural Mechanisms of Attention in Solving the Binding Problem
Reynolds, J. H., & Desimone, R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80819-3 · Cited by 364 · see citing works
What do the basal ganglia do?
Brown, P., & MARSDEN, C. D. (1998) · The Lancet · doi:10.1016/s0140-6736(97)11225-9 · Cited by 364 · see citing works
Arousal--Revisiting the Reticular Activating System
Steriade, M. (1996) · Science · doi:10.1126/science.272.5259.225 · Cited by 350 · see citing works
Beta EEG activity and insomnia
Perlis, M. L., Merica, H., Smith, M. T., & Giles, D. E. (2001) · Sleep Medicine Reviews · doi:10.1053/smrv.2001.0151 · Cited by 345 · see citing works
Human gamma-band activity: A review on cognitive and behavioral correlates and network models
Herrmann, C. S., Fründ, I., & Lenz, D. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.09.001 · Cited by 337 · see citing works
Global Forebrain Dynamics Predict Rat Behavioral States and Their Transitions
Gervasoni, D., Lin, S., Ribeiro, S. T. G., Soares, E. S., Pantoja, J., & Nicolelis, M. A. L. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3524-04.2004 · Cited by 323 · see citing works
The Binding Problem
Roskies, A. L. (1999) · Neuron · doi:10.1016/s0896-6273(00)80817-x · Cited by 334 · see citing works
MORE THAN A MARKER: INTERACTION BETWEEN THE CIRCADIAN REGULATION OF TEMPERATURE AND SLEEP, AGE-RELATED CHANGES, AND TREATMENT POSSIBILITIES
VanSomeren, E. J. W. (2000) · Chronobiology International · doi:10.1081/cbi-100101050 · Cited by 329 · see citing works
Coherent oscillations and short-term plasticity in corticothalamic networks
Steriade, M. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01407-1 · Cited by 321 · see citing works
Dynamics of Spontaneous Activity in Neocortical Slices
Mao, B.-Q., Hamzei‐Sichani, F., Aronov, D., Froemke, R. C., & Yuste, R. (2001) · Neuron · doi:10.1016/s0896-6273(01)00518-9 · Cited by 319 · see citing works
Solutions to the Binding Problem
Treisman, A. (1999) · Neuron · doi:10.1016/s0896-6273(00)80826-0 · Cited by 314 · see citing works
Linkage disequilibrium between the beta frequency of the human EEG and a GABA A receptor gene locus
Bernice Porjesz, A., Almasy, L. A., Edenberg, H. J., Wang, K., Chorlian, D. B., Foroud, T., Goate, A., Rice, J. P., O’Connor, S., Rohrbaugh, J., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.052716399 · Cited by 311 · see citing works
Residual cerebral activity and behavioural fragments can remain in the persistently vegetative brain
Schiff, N. D., Ribary, U., Moreno, D. R., Beattie, B., Kronberg, E., Blasberg, R., Giacino, J., McCagg, C., Fins, J. J., Llinás, R., et al. (2002) · Brain · doi:10.1093/brain/awf131 · Cited by 306 · see citing works
Self-citation
Synchronization of fast (30-40 Hz) spontaneous oscillations in intrathalamic and thalamocortical networks
Steriade, M., Contreras, D., Amzica, F., & Timofeev, I. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-08-02788.1996 · Cited by 404 · see citing works
Gamma frequency oscillation in the hippocampus of the rat: intracellular analysis in vivo
Penttonen, M., Kamondi, A., Acsády, L., & Buzsáki, G. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00096.x · Cited by 296 · see citing works
Oscillatory gamma activity in humans: a possible role for object representation
Bertrand, O., & Tallon‐Baudry, C. (2000) · International Journal of Psychophysiology · doi:10.1016/s0167-8760(00)00166-5 · Cited by 299 · see citing works
Expression of Cx36 in mammalian neurons
Condorelli, D. F., Belluardo, N., Salinaro, A. T., & Mudò, G. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00068-5 · Cited by 293 · see citing works
Cortically projecting basal forebrain parvalbumin neurons regulate cortical gamma band oscillations
Kim, T., Thankachan, S., McKenna, J. T., McNally, J. M., Yang, C. Z., Choi, J. H., Chen, L., Kocsis, B., Deisseroth, K. A., Strecker, R. E., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1413625112 · Cited by 282 · see citing works
Excess of High Frequency Electroencephalogram Oscillations in Boys with Autism
Orekhova, E. V., Stroganova, T. A., Nygren, G., Tsetlin, M. M., Posikera, I. N., Gillberg, C., & Elam, M. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.029 · Cited by 286 · see citing works
Interaction between neocortical and hippocampal networks via slow oscillations
Sirota, A., & Buzsáki, G. (2005) · Thalamus and Related Systems · doi:10.1017/s1472928807000258 · Cited by 270 · see citing works
Separation of speech from interfering sounds based on oscillatory correlation
Wang, D. L., & Brown, G. J. (1999) · IEEE Transactions on Neural Networks · doi:10.1109/72.761727 · Cited by 285 · see citing works
Sleep-Induced Changes in Associative Memory
Stickgold, R., Scott, L., Rittenhouse, C., & Hobson, J. A. (1999) · Journal of Cognitive Neuroscience · doi:10.1162/089892999563319 · Cited by 284 · see citing works
Ongoing spontaneous activity controls access to consciousness: a neuronal model for inattentional blindness
Dehaene, S., & Changeux, J.-P. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030141 · Cited by 329 · see citing works
The Slow Oscillation in Cortical and Thalamic Networks: Mechanisms and Functions
Neske, G. T. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2015.00088 · Cited by 283 · see citing works
Dynamics of the brain at global and microscopic scales: Neural networks and the EEG
Wright, J. J., & Liley, D. T. J. (1996) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00042679 · Cited by 273 · see citing works
Temporal binding via cortical coincidence detection of specific and nonspecific thalamocortical inputs: A voltage-dependent dye-imaging study in mouse brain slices
Llinás, R. R., Leznik, E., & Urbano, F. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012604899 · Cited by 262 · see citing works
Self-citation
The neurophysics of consciousness
John, E. R. (2002) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00142-x · Cited by 262 · see citing works
High-frequency γ electroencephalogram activity in association with sleep-wake states and spontaneous behaviors in the rat
Maloney, K. J., Cape, E., Gotman, J., & Jones, B. E. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00298-9 · Cited by 258 · see citing works
What it is like to see: A sensorimotor theory of perceptual experience
O'Regan, J. K., & Noë, A. (2001) · Synthese · doi:10.1023/a:1012699224677 · Cited by 257 · see citing works
Neuronal Computations with Stochastic Network States
Alain Destexhe, A., & Contreras, D. (2006) · Science · doi:10.1126/science.1127241 · Cited by 257 · see citing works
The role of REM sleep theta activity in emotional memory
Hutchison, I. C., & Rathore, S. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01439 · Cited by 245 · see citing works
Sleeping brain, learning brain. The role of sleep for memory systems
Peigneux, P., Laureys, S., Delbeuck, X., & Maquet, P. (2001) · Neuroreport · doi:10.1097/00001756-200112210-00001 · Cited by 347 · see citing works
Dynamic Properties of Corticothalamic Neurons and Local Cortical Interneurons Generating Fast Rhythmic (30–40 Hz) Spike Bursts
Steriade, M., Timofeev, I., Dürmüller, N., & Grenier, F. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.1.483 · Cited by 254 · see citing works

Coherent 40-Hzoscillation characterizes dreamstate inhumans (cognition/sleep-wakefulness/consiousness/magnetoencephalography)
Ursribary (1993)
Cognitive Temporal Binding and its Relation to 40Hz Activity in Humans: Alteration During Dyslexia
Ribary, U., Joliot, M., Miller, S. L., Kronberg, E., Cappell, J., Tallal, P. A., & Llinas, R. H. (2000) · Springer eBooks · doi:10.1007/978-1-4612-1260-7_237 · Cited by 4 · see citing works
Self-citation
Coherent neocortical 40‐Hz oscillations are not present during <scp>REM</scp> sleep
Castro, S., Falconi, A., Chase, M. H., & Torterolo, P. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12143 · Cited by 54 · see citing works
Cortical activation patterns herald successful dream recall after NREM and REM sleep
Chellappa, S. L., Frey, S., Knoblauch, V., & Cajochen, C. (2011) · Biological Psychology · doi:10.1016/j.biopsycho.2011.03.004 · Cited by 75 · see citing works
Theta and alpha oscillations during sleep predict subsequent dream recall.
Moroni, F., Marzano, C., DE GENNARO, L., Mauro, F., Curcio, G., & Ferrara, M. (2010) · IRIS Research product catalog (Sapienza University of Rome)

Authors: Llinás, R., & Ribary, U.
Affiliations: Department of Physiology and Biophysics, New York University Medical Center, NY 10016.
NYU Langone Health (US)
ORCID: Ribary, U
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 1993-03
Volume: 90
Issue: 5
Pages: 2078-2081
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.90.5.2078
PMC: PMC46024
OpenAlex: W1972268296
Cited by: 962
References: 19
Citations by year: 2026: 6 · 2025: 4 · 2024: 18 · 2023: 11 · 2022: 10 · 2021: 12 · 2020: 9 · 2019: 16 · 2018: 15 · 2017: 28 · 2016: 28 · 2015: 27 · 2014: 25 · 2013: 26 · 2012: 32
FWCI: 28.04
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Creativity in Education and Neuroscience
Keywords: 40 Hz oscillations, REM sleep, delta sleep, dream states, temporal binding, brain coherence
MeSH terms: Adult, Brain, Dreams, Humans, Magnetics, Sleep, Sleep, REM, Wakefulness

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Coherent 40-Hz oscillation characterizes dream state in humans.

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