High-intensity resistance training improves glycemic control in older patients with type 2 diabetes

Dunstan, David W.; Daly, Robin M.; Owen, Neville; Jolley, Damien; de Courten, Maximilian; Shaw, Jonathan; Zimmet, Paul

doi:10.2337/diacare.25.10.1729

Cited by 771Physical Activity and HealthDiabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

High-intensity resistance training improves glycemic control in older patients with type 2 diabetes

Open access

Dunstan, David W., Daly, Robin M., Owen, Neville, Jolley, Damien, de Courten, Maximilian, Shaw, Jonathan, Zimmet, Paul·2002·Diabetes Care

DOI 10.2337/diacare.25.10.1729

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE—To examine the effect of high-intensity progressive resistance training combined with moderate weight loss on glycemic control and body composition in older patients with type 2 diabetes. RESEARCH DESIGN AND METHODS—Sedentary, overweight men and women with type 2 diabetes, aged 60–80 years (n = 36), were randomized to high-intensity progressive resistance training plus moderate weight loss (RT & WL group) or moderate weight loss plus a control program (WL group). Clinical and laboratory measurements were assessed at 0, 3, and 6 months. RESULTS—HbA1c fell significantly more in RT & WL than WL at 3 months (0.6 ± 0.7 vs. 0.07 ± 0.8%, P < 0.05) and 6 months (1.2 ± 1.0 vs. 0.4 ± 0.8%, P < 0.05). Similar reductions in body weight (RT & WL 2.5 ± 2.9 vs. WL 3.1 ± 2.1 kg) and fat mass (RT & WL 2.4 ± 2.7 vs. WL 2.7 ± 2.5 kg) were observed after 6 months. In contrast, lean body mass (LBM) increased in the RT & WL group (0.5 ± 1.1 kg) and decreased in the WL group (0.4 ± 1.0) after 6 months (P < 0.05). There were no between-group differences for fasting glucose, insulin, serum lipids and lipoproteins, or resting blood pressure. CONCLUSIONS—High-intensity progressive resistance training, in combination with moderate weight loss, was effective in improving glycemic control in older patients with type 2 diabetes. Additional benefits of improved muscular strength and LBM identify high-intensity resistance training as a feasible and effective component in the management program for older patients with type 2 diabetes.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.2337/diacare.25.10.1729

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Resistance exercise training also benefits blood glucose control and insulin action in type 2 diabetes.
“Resistance exercise training also benefits BG control and insulin action in type 2 diabetes ( 46 , 65 , 115 , 116 , 118 , 246 ).”
From Exercise and Type 2 Diabetes (2010) · cites this paper as [65]
The discussion (p. 5) reports that high-intensity resistance training improved HbA1c in older patients with type 2 diabetes, supporting the blood-glucose-control claim. It also reports improved insulin sensitivity in earlier studies, but this trial found no significant between-group difference in HOMA-estimated insulin sensitivity (p. 6). Thus, this source does not establish an insulin-action benefit in its own participants. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Exercise intervention studies showing the greatest effect on blood glucose control have all involved supervision of exercise sessions by qualified exercise trainers.
“Exercise intervention studies showing the greatest effect on BG control have all involved supervision of exercise sessions by qualified exercise trainers ( 34 , 65 , 196 , 238 ).”
From Exercise and Type 2 Diabetes (2010) · cites this paper as [65]
The Exercise intervention section (p. 2) says all sessions in this study were supervised, and the Results (p. 1) report improved HbA1c. The paper does not establish that the studies with the greatest effects all used supervision, or identify the supervisors as qualified exercise trainers. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Twelve RCTs compared the effects of a dietary weight loss intervention alone to a combination of the same dietary intervention with an exercise intervention in older persons.
“Twelve RCTs were identified that compared the effects of a dietary weight loss intervention alone to a combination of the same dietary intervention with an exercise intervention in older persons (288)(289)(290)(291)(292)(293)(294)(295)(296)(297)(298)(299).”
From ESPEN practical guideline: Clinical nutrition and hydration in geriatrics (2022) · cites this paper as [297]
For several physical and strength-performance measures, greater improvements were observed in the combined groups than in the diet-only groups.
“Moreover, for several physical and strengthperformance measures, greater improvements were observed in the combined groups than in the diet-only groups (288-291, 293-297, 299).”
From ESPEN practical guideline: Clinical nutrition and hydration in geriatrics (2022) · cites this paper as [297]
In ten trials, a weight-reducing diet alone resulted in the desired weight loss, which consisted of fat mass as well as lean mass.
“In ten trials, a weight-reducing diet alone resulted in the desired weight loss, which consisted of fat mass as well as lean mass (290)(291)(292)(294)(295)(296)(297)(298)(299).”
From ESPEN practical guideline: Clinical nutrition and hydration in geriatrics (2022) · cites this paper as [297]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423 · see citing works
Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502 · see citing works
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
(1998) · The Lancet · doi:10.1016/s0140-6736(98)07019-6 · Cited by 20,023 · see citing works
Untitled work
(2014) · Medical Entomology and Zoology · Cited by 9,400 · see citing works
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.
Turner, R. C., Fox, C., Matthews, McElroy, H. H., Cull, C. A., Holman, R. R., Neil, P., Hadden, D. R., Wright, D., Manley, E., et al. (1998) · The Lancet · Cited by 8,419 · see citing works
Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women.
Pouliot, M.-C., Despres, J., Lemieux, S., Moorjani, S., Bouchard, C., Tremblay, A., Nadeau, A., & Lupien, P. (1994) · American Journal of Cardiology · doi:10.1016/0002-9149(94)90676-9 · Cited by 2,238 · see citing works
PHYSICAL ACTIVITY ASSESSMENT METHODOLOGY IN THE FIVE-CITY PROJECT1
SALLIS, J. F., HASKELL, W. L., WOOD, P. D., FORTMANN, S. P., ROGERS, T., BLAIR, S. N., & PAFFENBARGER, R. S. (1985) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113987 · Cited by 1,716 · see citing works
Strength conditioning in older men: skeletal muscle hypertrophy and improved function
Frontera, W. R., Meredith, C. N., O'Reilly, K. P., Knuttgen, H. G., & Evans, W. J. (1988) · Journal of Applied Physiology · doi:10.1152/jappl.1988.64.3.1038 · Cited by 1,386 · see citing works
Resistance Exercise in Individuals With and Without Cardiovascular Disease
Pollock, M. L., Franklin, B. A., Balady, G. J., CHAITMAN, B. R., Fleg, J. L., Fletcher, B. J., Limacher, M. C., Piña, I. L., Stein, R. A., Williams, M. A., et al. (2000) · Circulation · doi:10.1161/01.cir.101.7.828 · Cited by 1,054 · see citing works
The rising prevalence of diabetes and impaired glucose tolerance: the Australian Diabetes, Obesity and Lifestyle Study.
Dunstan, D., Zimmet, P., Welborn, T., de Courten, M., Cameron, A., Sicree, R., Dwyer, T., Colagiuri, S., Jolley, D., Knuiman, M., et al. (2002) · Diabetes Care · doi:10.2337/diacare.25.5.829 · Cited by 1,018 · see citing works
Self-citation
Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of European Prospective Investigation of Cancer and Nutrition (EPIC-Norfolk)
Khaw, K. (2001) · BMJ · doi:10.1136/bmj.322.7277.15 · Cited by 1,014 · see citing works
Response of blood lipids to exercise training alone or combined with dietary intervention
LEON, A. S., & SANCHEZ, O. A. (2001) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200106001-00021 · Cited by 662 · see citing works
Exercise and Type 2 Diabetes
(2000) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200007000-00024 · Cited by 604 · see citing works
Exercise characteristics and the blood pressure response to dynamic physical training
FAGARD, R. H. (2001) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200106001-00018 · Cited by 561 · see citing works
Effect of physical exercise on sensitivity and responsiveness to insulin in humans
Mikines, K. J., Sonne, B., Farrell, P. A., Tronier, B., & Galbo, H. (1988) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1988.254.3.e248 · Cited by 538 · see citing works
Positive adaptations to weight-lifting training in the elderly
Brown, A. B., McCartney, N., & Sale, D. G. (1990) · Journal of Applied Physiology · doi:10.1152/jappl.1990.69.5.1725 · Cited by 360 · see citing works
Combined aerobic and resistance exercise improves glycemic control and fitness in type 2 diabetes
Maiorana, A., O’Driscoll, G., Goodman, C., Taylor, R. R., & GREEN, D. J. (2002) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(01)00368-0 · Cited by 353 · see citing works
A Randomized Controlled Trial of Weight Reduction and Exercise for Diabetes Management in Older African-American Subjects
Agurs‐Collins, T., Kumanyika, S., Have, T. R. T., & Adams-Campbell, L. L. (1997) · Diabetes Care · doi:10.2337/diacare.20.10.1503 · Cited by 347 · see citing works
Increased energy requirements and changes in body composition with resistance training in older adults
Campbell, W. W., Crim, M. C., Young, V. R., & Evans, W. (1994) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/60.2.167 · Cited by 330 · see citing works
Strength training increases insulin action in healthy 50- to 65-yr-old men
Miller, J. P., Pratley, R. E., Goldberg, A. P., Gordon, P., Rubin, M., Treuth, M. S., Ryan, A. S., & Hurley, B. F. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.77.3.1122 · Cited by 282 · see citing works
Resistance Training Improves Insulin Sensitivity in NIDDM Subjects Without Altering Maximal Oxygen Uptake
Ishii, T., Yamakita, T., Satō, T., Tanaka, S., & Fujii, S. (1998) · Diabetes Care · doi:10.2337/diacare.21.8.1353 · Cited by 276 · see citing works
Studies on the mechanism of improved glucose control during regular exercise in Type 2 (non-insulin-dependent) diabetes
Schneider, S. H., Amorosa, L. F., Khachadurian, A. K., & Ruderman, N. B. (1984) · Diabetologia · doi:10.1007/bf00266036 · Cited by 257 · see citing works
Muscle Strength and Fiber Adaptations to a Year-long Resistance Training Program in Elderly Men and Women
Pyka, G., Lindenberger, E. C., Charette, S. L., & Marcus, R. (1994) · Journal of Gerontology · doi:10.1093/geronj/49.1.m22 · Cited by 253 · see citing works
Effects of strength training on total and regional body composition in older men
Treuth, M. S., Ryan, A. S., Pratley, R. E., Rubin, M. A., Miller, J. P., Nicklas, B. J., Sorkin, J. D., Harman, S. M., Goldberg, A. P., & Hurley, B. F. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.77.2.614 · Cited by 235 · see citing works
Effects of aerobic or resistance exercise and/or diet on glucose tolerance and plasma insulin levels in obese men.
Rice, B. L., Janssen, I., Hudson, R., & Ross, R. (1999) · Diabetes Care · doi:10.2337/diacare.22.5.684 · Cited by 227 · see citing works
Resistance weight training during caloric restriction enhances lean body weight maintenance
Ballor, D. L., Katch, V., Becque, M. D., & Marks, C. (1988) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/47.1.19 · Cited by 222 · see citing works
Resistance training improves the metabolic profile in individuals with type 2 diabetes
Honkola, A., Forsén, T. J., & Eriksson, J. G. (1997) · Acta Diabetologica · doi:10.1007/s005920050082 · Cited by 203 · see citing works
Aerobic versus strength training for risk factor intervention in middle-aged men at high risk for coronary heart disease
SMUTOK, M. A., Reece, C., Kokkinos, P. F., Farmer, C., Dawson, P., Shulman, R. S., DeVane-Bell, J., Patterson, J., Charabogos, C., Goldberg, A. P., et al. (1993) · Metabolism · doi:10.1016/0026-0495(93)90032-j · Cited by 197 · see citing works
Effects of a short-term circuit weight training program on glycaemic control in NIDDM
Dunstan, D. W., Puddey, I. B., Beilin, L. J., Burke, V., Morton, A. R., & Stanton, K. G. (1998) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(98)00027-8 · Cited by 193 · see citing works
Self-citation
Exercise in a behavioural weight control programme for obese patients with Type 2 (non-insulin-dependent) diabetes
Wing, R. R., Epstein, L. H., Paternostro-Bayles, M., Kriska, A. M., Nowalk, M. P., & Gooding, W. E. (1988) · Diabetologia · doi:10.1007/bf00265375 · Cited by 188 · see citing works
Physiological response to circuit weight training in borderline hypertensive subjects
HARRIS, K. A., & Holly, R. G. (1987) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-198706000-00011 · Cited by 181 · see citing works
Effects of Exercise on Body Composition and Functional Capacity of the Elderly
Schwartz, R. S., & Evans, W. J. (1995) · The Journals of Gerontology Series A · doi:10.1093/gerona/50a.special_issue.147 · Cited by 169 · see citing works
Effects of Resistance Training and Endurance Training on Insulin Sensitivity in Nonobese, Young Women: A Controlled Randomized Trial
Poehlman, E. T. (2000) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.7.2463 · Cited by 151 · see citing works
Effects of aerobic physical exercise in the elderly with type 2 diabetes mellitus
Tessier, D., Ménard, J., Fülöp, T., Ardilouze, J., Roy, M.-A., Dubuc, N., Dubois, M., & Gauthier, P. (2000) · Archives of Gerontology and Geriatrics · doi:10.1016/s0167-4943(00)00076-5 · Cited by 150 · see citing works
Resistance Training in the Treatment of Non-Insulin-Dependent Diabetes Mellitus
Eriksson, J. G., TAIMELA, S. P., Eriksson, K., Parviainen, S., Peltonen, J. T. K., & Kujala, U. M. (1997) · International Journal of Sports Medicine · doi:10.1055/s-2007-972627 · Cited by 148 · see citing works
Effects of diet and exercise interventions on control and quality of life in non-insulin-dependent diabetes mellitus
Kaplan, R. M., Hartwell, S. L., Wilson, D. K., & Wallace, J. P. (1987) · Journal of General Internal Medicine · doi:10.1007/bf02596443 · Cited by 145 · see citing works
The Independent and Combined Effects of Aerobic Exercise and Dietary Fish Intake on Serum Lipids and Glycemic Control in NIDDM: A randomized controlled study
Dunstan, D. W., Mori, T. A., Puddey, I. B., Beilin, L. J., Burke, V., Morton, A. R., & Stanton, K. G. (1997) · Diabetes Care · doi:10.2337/diacare.20.6.913 · Cited by 128 · see citing works
Self-citation
Resistive Training Increases Insulin Action in Postmenopausal Women
Ryan, A. S., Pratley, R., Goldberg, A. P., & Elahi, D. (1996) · The Journals of Gerontology Series A · doi:10.1093/gerona/51a.5.m199 · Cited by 104 · see citing works
Effects of Physical Training on Metabolic Control in Elderly Type 2 Diabetes Mellitus Patients
Ligtenberg, P. C., Hoekstra, J. B. L., Bol, E., Zonderland, M. L., & Erkelens, D. W. (1997) · Clinical Science · doi:10.1042/cs0930127 · Cited by 103 · see citing works
The role of progressive resistance training and nutrition in the preservation of lean body mass in the elderly.
Fielding, R. A. (1995) · Journal of the American College of Nutrition · doi:10.1080/07315724.1995.10718547 · Cited by 95 · see citing works
Strength training does not improve lipoprotein-lipid profiles in men at risk for CHD
Kokkinos, P. F., Hurley, B. F., SMUTOK, M. A., FARMER, C., REECE, C., Shulman, R. S., Charabogos, C., PATTERSON, J., WILL, S., DeVane-Bell, J., et al. (1991) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199110000-00004 · Cited by 66 · see citing works
Untitled work
(1995) · PubMed · Cited by 44 · see citing works
The effect of resistance training on blood pressure in normotensive women
Gilders, R. M., Malicky, E. S., Falkel, J. E., Staron, R. S., & Dudley, G. A. (1991) · Clinical Physiology · doi:10.1111/j.1475-097x.1991.tb00659.x · Cited by 13 · see citing works

Flagged first, then by citations

Research works printed but not linked: 1

[21]21. Blair SN: How to assess exercise habits and physical fitness. In Behavioral Health . Miller NE, Matarazzo JD, Weiss SM, Herd JA, Eds. New York, John Wiley & Sons, 1984, p. 424-447

Sorted by citations

Health benefits of physical activity: the evidence
Warburton, D. E. R. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.051351 · Cited by 8,007 · see citing works
Standards of medical care in diabetes—2014
American Diabetes Association (2014) · Diabetes Care · doi:10.2337/dc14-s014 · Cited by 4,572 · see citing works
Standards of medical care in diabetes—2013
American Diabetes Association (2013) · Diabetes Care · doi:10.2337/dc13-s011 · Cited by 4,369 · see citing works
Standards of medical care in diabetes 2010
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc10-s011 · Cited by 3,470 · see citing works
Standards of medical care in diabetes—2011
American Diabetes Association (2011) · Diabetes Care · doi:10.2337/dc11-s011 · Cited by 2,880 · see citing works
Standards of Medical Care in Diabetes—2009
American Diabetes Association (2009) · Diabetes Care · doi:10.2337/dc09-s013 · Cited by 2,167 · see citing works
Exercise and Type 2 Diabetes
Colberg, S. R., Sigal, R. J., Fernhall, B., Regensteiner, J. G., Blissmer, B. J., Rubin, R. R., Chasan-Taber, L., Albright, A. L., & Braun, B. (2010) · Diabetes Care · doi:10.2337/dc10-9990 · Cited by 1,955 · see citing works
“Exercise intervention studies showing the greatest effect on BG control have all involved supervision of exercise sessions by qualified exercise trainers (34,65,196,238).”
Standards of Medical Care in Diabetes—2008
American Diabetes Association (2008) · Diabetes Care · doi:10.2337/dc08-s012 · Cited by 1,377 · see citing works
Physical Activity Advice Only or Structured Exercise Training and Association With HbA <sub>1c</sub> Levels in Type 2 Diabetes: A Systematic Review and Meta-analysis
Umpierre, D. (2011) · JAMA · doi:10.1001/jama.2011.576 · Cited by 1,358 · see citing works
Resistance Training for Older Adults: Position Statement From the National Strength and Conditioning Association
Fragala, M. S., Cadore, E. L., Dorgo, S., Izquierdo, M., Kraemer, W. J., Peterson, M. D., & Ryan, E. D. (2019) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003230 · Cited by 1,290 · see citing works
Progressive resistance strength training for improving physical function in older adults
Liu, C.-J., & Latham, N. K. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002759.pub2 · Cited by 1,258 · see citing works
Resistance Exercise in Individuals With and Without Cardiovascular Disease: 2007 Update: A Scientific Statement From the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism
Williams, M. A., Haskell, W. L., Ades, P. A., Amsterdam, E. A., Bittner, V., Franklin, B. A., Gulanick, M., Laing, S. T., & Stewart, K. J. (2007) · Circulation · doi:10.1161/circulationaha.107.185214 · Cited by 1,211 · see citing works
Exercise/Physical Activity in Individuals with Type 2 Diabetes: A Consensus Statement from the American College of Sports Medicine
KANALEY, J. A., COLBERG, S. R., CORCORAN, M. H., MALIN, S. K., RODRIGUEZ, N. R., CRESPO, C. J., KIRWAN, J. P., & ZIERATH, J. R. (2022) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002800 · Cited by 931 · see citing works
Physical Activity/Exercise and Type 2 Diabetes
Sigal, R. J., Kenny, G. P., Wasserman, D. H., Castaneda-Sceppa, C., & White, R. D. (2006) · Diabetes Care · doi:10.2337/dc06-9910 · Cited by 949 · see citing works
Effects of Different Modes of Exercise Training on Glucose Control and Risk Factors for Complications in Type 2 Diabetic Patients
Snowling, N. J., & Hopkins, W. G. (2006) · Diabetes Care · doi:10.2337/dc06-1317 · Cited by 813 · see citing works
Resistance Training is Medicine: Effects of Strength Training on Health
Westcott, W. L. (2012) · Current Sports Medicine Reports · doi:10.1249/jsr.0b013e31825dabb8 · Cited by 778 · see citing works
Physical Activity/Exercise and Type 2 Diabetes
Sigal, R. J., Kenny, G. P., Wasserman, D. H., & Castaneda-Sceppa, C. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2518 · Cited by 763 · see citing works
Exercise for type 2 diabetes mellitus
Thomas, D., Elliott, E. J., & Naughton, G. A. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002968.pub2 · Cited by 728 · see citing works
Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes
Holten, M. K., Zacho, M., Gaster, M., Juel, C., Wojtaszewski, J. F. P., & Dela, F. (2004) · Diabetes · doi:10.2337/diabetes.53.2.294 · Cited by 615 · see citing works
Influence of Resistance Exercise on Lean Body Mass in Aging Adults: A Meta-Analysis
PETERSON, M. D., SEN, A., & GORDON, P. M. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181eb6265 · Cited by 558 · see citing works
Exercise and Type 2 Diabetes: American College of Sports Medicine and the American Diabetes Association Joint Position Statement
(2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181eeb61c · Cited by 567 · see citing works
ESPEN practical guideline: Clinical nutrition and hydration in geriatrics
Volkert, D., Beck, A. M., Cederholm, T., Cruz-Jentoft, A., Hooper, L., Kiesswetter, E., Maggio, M., Raynaud-Simon, A., Sieber, C., Sobotka, L., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.01.024 · Cited by 516 · see citing works
Physical activity in prevention and treatment of the metabolic syndrome
Lakka, T. A., & Laaksonen, D. E. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h06-113 · Cited by 482 · see citing works
The essential role of exercise in the management of type 2 diabetes
Kirwan, J. P., Sacks, J., & Nieuwoudt, S. (2017) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.84.s1.03 · Cited by 467 · see citing works
Exercise training can modify the natural history of diabetic peripheral neuropathy
Balducci, S., Iacobellis, G., Parisi, L., Di Biase, N., Calandriello, E., Leonetti, F., & Fallucca, F. (2006) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2005.07.005 · Cited by 427 · see citing works
The relative benefits of endurance and strength training on the metabolic factors and muscle function of people with type 2 diabetes mellitus
Cauza, E., Hanusch-Enserer, U., Strasser, B., Ludvik, B., Metz-Schimmerl, S., Pacini, G., Wagner, O., Georg, P., Prager, R., Kostner, K., et al. (2005) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2005.01.007 · Cited by 392 · see citing works
The benefits of strength training for older adults
SEGUIN, R. (2003) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(03)00177-6 · Cited by 354 · see citing works
Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial
Andrews, R., Cooper, A., Montgomery, A., Norcross, A., Peters, T., Sharp, D., Jackson, N., Fitzsimons, K., Bright, J., Coulman, K., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60442-x · Cited by 302 · see citing works
Resistance training improves metabolic health in type 2 diabetes: a systematic review
Gordon, B. A., Benson, A. C., Bird, S. R., & Fraser, S. F. (2009) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2008.11.024 · Cited by 293 · see citing works
Exercise prescription for patients with type 2 diabetes and pre-diabetes: a position statement from Exercise and Sport Science Australia
Hordern, M. D., Dunstan, D. W., Prins, J. B., Baker, M. K., Singh, M. A. F., & Coombes, J. S. (2012) · Journal of Science and Medicine in Sport · doi:10.1016/j.jsams.2011.04.005 · Cited by 273 · see citing works
Self-citation
Alterations in muscle attenuation following detraining and retraining in resistance-trained older adults
Taaffe, D. R., Henwood, T. R., Nalls, M. A., Walker, D. G., Lang, T. F., & Harris, T. B. (2009) · Gerontology · doi:10.1159/000182084 · Cited by 269 · see citing works
Resistance Training in the Treatment of the Metabolic Syndrome: A Systematic Review and Meta-Analysis of the Effect of Resistance Training on Metabolic Clustering in Patients with Abnormal Glucose Metabolism
Strasser, B., Siebert, U., & Schobersberger, W. (2010) · Sports Medicine · doi:10.2165/11531380-000000000-00000 · Cited by 258 · see citing works
]. The Influence of Age on the Effects of Lifestyle Modification and Metformin in Prevention of Diabetes
The Diabetes Prevention Program Research Group [Prepared by Jill Crandall, D. S. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.10.1075 · Cited by 254 · see citing works
A high-protein diet with resistance exercise training improves weight loss and body composition in overweight and obese patients with type 2 diabetes
Wycherley, T. P., Noakes, M., Clifton, P. M., Cleanthous, X., Keogh, J. B., & Brinkworth, G. D. (2010) · Diabetes Care · doi:10.2337/dc09-1974 · Cited by 240 · see citing works
“Cardiometabolic outcomes and glycemic control Overall, blood pressure, lipids, glucose, A1C, and CRP were reduced (P 0.02) (Table 2) with no difference between treatment groups (P 0.37), diet composition (P 0.27), or exercise participation (P 0.21).”
BackgroundInfluential
Evidence for Resistance Training as a Treatment Therapy in Obesity
Strasser, B., & Schobersberger, W. (2011) · Journal of Obesity · doi:10.1155/2011/482564 · Cited by 220 · see citing works
Home-based resistance training is not sufficient to maintain improved glycemic control following supervised training in older individuals with type 2 diabetes
Dunstan, D. W., Daly, R. M., Owen, N., Jolley, D., Vulikh, E., Shaw, J., & Zimmet, P. (2005) · Diabetes Care · doi:10.2337/diacare.28.1.3 · Cited by 194 · see citing works
Self-citation
Regulation of Skeletal Muscle Glucose Transport and Glucose Metabolism by Exercise Training
Evans, P. L., McMillin, S. L., Weyrauch, L. A., & Witczak, C. A. (2019) · Nutrients · doi:10.3390/nu11102432 · Cited by 190 · see citing works
Resistance training induces qualitative changes in muscle morphology, muscle architecture, and muscle function in elderly postoperative patients
Suetta, C., Andersen, J. L., Dalgas, U., Berget, J., Koskinen, S., Aagaard, P., Magnusson, S. P., & Kjaer, M. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01354.2007 · Cited by 184 · see citing works
Resistance Exercise Intensity is Correlated with Attenuation of HbA1c and Insulin in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Liu, Y., Ye, W., Chen, Q., Zhang, Y., Kuo, C.-H., & Korivi, M. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16010140 · Cited by 176 · see citing works
Battling Insulin Resistance in Elderly Obese People With Type 2 Diabetes
Willey, K. A., & Singh, M. A. F. (2003) · Diabetes Care · doi:10.2337/diacare.26.5.1580 · Cited by 165 · see citing works
Diet, exercise or diet with exercise: comparing the effectiveness of treatment options for weight-loss and changes in fitness for adults (18–65 years old) who are overfat, or obese; systematic review and meta-analysis
Clark, J. E. (2015) · Journal of Diabetes & Metabolic Disorders · doi:10.1186/s40200-015-0154-1 · Cited by 158 · see citing works
Evidence-based practice guideline for the treatment for diabetes in Japan 2013
Tajima, N., Noda, M., Origasa, H., Noto, H., Yabe, D., Fujita, Y., Goto, A., Fujimoto, K., Sakamoto, M., & Haneda, M. (2015) · Diabetology International · doi:10.1007/s13340-015-0206-2 · Cited by 154 · see citing works
Moderate exercise attenuates the loss of skeletal muscle mass that occurs with intentional caloric restriction-induced weight loss in older, overweight to obese adults
Chomentowski, P., Dube, J. J., Amati, F., Stefanovic-Racic, M., Zhu, S., Toledo, F. G. S., & Goodpaster, B. H. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glp007 · Cited by 137 · see citing works
Resistance Training Prevents Muscle Loss Induced by Caloric Restriction in Obese Elderly Individuals: A Systematic Review and Meta-Analysis
Sardeli, A. V., Komatsu, T. R., Mori, M. A., Gáspari, A. F., & Chacon-Mikahil, M. P. T. (2018) · Nutrients · doi:10.3390/nu10040423 · Cited by 138 · see citing works
“One of these studies [24] reported part of its data from a previous publication [25], so both studies were included as one.”
Background
Comparison of combined aerobic and high-force eccentric resistance exercise with aerobic exercise only for people with type 2 diabetes mellitus
Marcus, R. L., Smith, S., Morrell, G., Addison, O., Dibble, L. E., Wahoff-Stice, D., & LaStayo, P. C. (2008) · Physical Therapy · doi:10.2522/ptj.20080124 · Cited by 137 · see citing works
Efficacy of interventions that include diet, aerobic and resistance training components for type 2 diabetes prevention: A systematic review with meta-analysis
Aguiar, E. J., Morgan, P. J., Collins, C. E., Plotnikoff, R. C., & Callister, R. (2014) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-11-2 · Cited by 135 · see citing works
Is a long-term aerobic plus resistance training program feasible for and effective on metabolic profiles in type 2 diabetic patients?
Balducci, S., Leonetti, F., Di Mario, U., & Fallucca, F. (2004) · Diabetes Care · doi:10.2337/diacare.27.3.841 · Cited by 131 · see citing works
Effect of moderate intensity resistance training during weight loss on body composition and physical performance in overweight older adults
Avila, J. J., Gutierres, J. A., Sheehy, M. E., Lofgren, I. E., & Delmonico, M. J. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1387-9 · Cited by 128 · see citing works
Improved endothelial function following a 14-month resistance exercise training program in adults with type 2 diabetes
Cohen, N. D., Dunstan, D. W., Robinson, C., Vulikh, E., Zimmet, P. Z., & Shaw, J. E. (2008) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2007.09.020 · Cited by 122 · see citing works
Self-citation
Does high-intensity resistance training maintain bone mass during moderate weight loss in older overweight adults with type 2 diabetes?
Daly, R. M., Dunstan, D. W., Owen, N., Jolley, D., Shaw, J. E., & Zimmet, P. Z. (2005) · Osteoporosis International · doi:10.1007/s00198-005-1906-4 · Cited by 118 · see citing works
Self-citation
Obesity, intentional weight loss and physical disability in older adults
Rejeski, W. J., Marsh, A. P., Chmelo, E., & Rejeski, J. J. (2010) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00679.x · Cited by 120 · see citing works
Exercise and Glycemic Control in Diabetes: Benefits, Challenges, and Adjustments to Pharmacotherapy
Gulve, E. A. (2008) · Physical Therapy · doi:10.2522/ptj.20080114 · Cited by 120 · see citing works
Resistance exercise training lowers HbA1c more than aerobic training in adults with type 2 diabetes
Bweir, S., Al-Jarrah, M., Almalty, A.-M., Maayah, M., Smirnova, I. V., Novikova, L., & Stehno-Bittel, L. (2009) · Diabetology & Metabolic Syndrome · doi:10.1186/1758-5996-1-27 · Cited by 117 · see citing works
Changes in Insulin Resistance and HbA1c Are Related to Exercise-Mediated Changes in Body Composition in Older Adults With Type 2 Diabetes
Mavros, Y., Kay, S., Anderberg, K. A., Baker, M. K., Wang, Y., Zhao, R., Meiklejohn, J., Climstein, M., O’Sullivan, A., de Vos, N., et al. (2013) · Diabetes Care · doi:10.2337/dc12-2196 · Cited by 118 · see citing works
The effects of resistance training on muscle and body fat mass and muscle strength in type 2 diabetic women
Kwon, H. R., Han, K. A., Ku, Y. H., Ahn, H. J., Koo, B.-K., Kim, H. C., & Min, K. W. (2010) · Korean Diabetes Journal · doi:10.4093/kdj.2010.34.2.101 · Cited by 108 · see citing works
"Not just another walking program": everyday activity supports You (EASY) model-a randomized pilot study for a parallel randomized controlled trial
Ashe, M. C., Winters, M., Hoppmann, C. A., Dawes, M. G., Gardiner, P. A., Giangregorio, L. M., Madden, K. M., McAllister, M. M., Wong, G., Puyat, J. H., et al. (2015) · Pilot and Feasibility Studies · doi:10.1186/2055-5784-1-4 · Cited by 103 · see citing works
Multicomponent, home-based resistance training for obese adults with type 2 diabetes: a randomized controlled trial
Plotnikoff, R. C., Eves, N., Jung, M., Sigal, R. J., Padwal, R., & Karunamuni, N. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.109 · Cited by 95 · see citing works
Exercise interventions in polypathological aging patients that coexist with diabetes mellitus: improving functional status and quality of life
Cadore, E. L., & Izquierdo, M. (2015) · AGE · doi:10.1007/s11357-015-9800-2 · Cited by 93 · see citing works
Structured Exercise in Obese Diabetic Patients with Chronic Kidney Disease: A Randomized Controlled Trial
Leehey, D. J., Collins, E., Kramer, H. J., Cooper, C., Butler, J., McBurney, C., Jelinek, C., Reda, D., Edwards, L., Garabedian, A., et al. (2016) · American Journal of Nephrology · doi:10.1159/000447703 · Cited by 93 · see citing works
Effects of intensity and volume on insulin sensitivity during acute bouts of resistance training
Black, L. E., Swan, P. D., & Alvar, B. A. (2010) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0b013e3181cbab6d · Cited by 87 · see citing works
Functional high-intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2 diabetes.
Fealy, C. E., Nieuwoudt, S., Foucher, J. A., Scelsi, A. R., Malin, S. K., Pagadala, M., Cruz, L. A., Li, M., Rocco, M., Burguera, B., et al. (2018) · Experimental Physiology · doi:10.1113/ep086844 · Cited by 84 · see citing works
Long-standing, insulin-treated type 2 diabetes patients with complications respond well to short-term resistance and interval exercise training
Praet, S. F. E., Jonkers, R. A. M., Schep, G., Stehouwer, C. D. A., Kuipers, H., Keizer, H. A., & van Loon, L. J. (2008) · European Journal of Endocrinology · doi:10.1530/eje-07-0169 · Cited by 80 · see citing works
Resistance Training and Older Adults with Type 2 Diabetes Mellitus: Strength of the Evidence
Hovanec, N., Sawant, A., Overend, T. J., Petrella, R. J., & Vandervoort, A. A. (2012) · Journal of Aging Research · doi:10.1155/2012/284635 · Cited by 79 · see citing works
The feasibility of progressive resistance training in women with polycystic ovary syndrome: a pilot randomized controlled trial
Vizza, L., Smith, C. A., Swaraj, S., Agho, K., & Cheema, B. S. (2016) · BMC Sports Science, Medicine and Rehabilitation · doi:10.1186/s13102-016-0039-8 · Cited by 74 · see citing works
Physical activity and risk of all-cause and cardiovascular disease mortality in diabetic adults from Great Britain: pooled analysis of 10 population-based cohorts
Sadarangani, K. P., Hamer, M., Mindell, J. S., Coombs, N. A., & Stamatakis, E. (2014) · Diabetes Care · doi:10.2337/dc13-1816 · Cited by 66 · see citing works
Does home-based exercise improve body mass index in patients with type 2 diabetes?
Krousel-Wood, M. A., Berger, L., Jiang, X., Blonde, L., Myers, L., & Webber, L. (2008) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2007.08.028 · Cited by 62 · see citing works
Resistance training attenuates circulating FGF-21 and myostatin and improves insulin resistance in elderly men with and without type 2 diabetes mellitus: A randomised controlled clinical trial
Shabkhiz, F., Khalafi, M., Rosenkranz, S., Karimi, P., & Moghadami, K. (2021) · European Journal of Sport Science · doi:10.1080/17461391.2020.1762755 · Cited by 64 · see citing works
Association between Physical Activity Advice Only or Structured Exercise Training with Blood Pressure Levels in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Figueira, F. R., Umpierre, D., Cureau, F. V., Zucatti, A. T. N., Dalzochio, M. B., Leitão, C. B., & Schaan, B. D. (2014) · Sports Medicine · doi:10.1007/s40279-014-0226-2 · Cited by 57 · see citing works
Difference between old and young adults in contribution of β‐cell function and sarcopenia in developing diabetes mellitus
Koo, B. K., Roh, E., Yang, Y. S., & Moon, M. K. (2016) · Journal of Diabetes Investigation · doi:10.1111/jdi.12392 · Cited by 48 · see citing works
Physical activity in the management of obesity in adults: A position statement from Exercise and Sport Science Australia
Johnson, N. A., Sultana, R. N., Brown, W. J., Bauman, A. E., & Gill, T. (2021) · Journal of Science and Medicine in Sport · doi:10.1016/j.jsams.2021.07.009 · Cited by 47 · see citing works
The impact of duration on effectiveness of exercise, the implication for periodization of training and goal setting for individuals who are overfat, a meta-analysis
Clark, J. (2016) · Biology of Sport · doi:10.5604/20831862.1212974 · Cited by 50 · see citing works
Effects of Aerobic Training, Resistance Training, or Both on Glycemic Control in Type 2 Diabetes: A Randomized Trial
Sigal, R. J., Kenny, G. P., Boulé, N. G., Wells, G. A., Prud'homme, D., Fortier, M., Reid, R. D., Tulloch, H., Coyle, D., Phillips, P., et al. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-6-200709180-00005 · Cited by 48 · see citing works
Metabolic training: New paradigms of exercise training for metabolic diseases with exercise calorimetry targeting individuals
Brun, J.-F., Jean, E., Ghanassia, E., Flavier, S., & Mercier, J. (2007) · Annales de Réadaptation et de Médecine Physique · doi:10.1016/j.annrmp.2007.04.008 · Cited by 48 · see citing works
Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle
Howlett, K. F., Sakamoto, K., Garnham, A., Cameron-Smith, D., & Hargreaves, M. (2007) · Diabetes · doi:10.2337/db06-1398 · Cited by 37 · see citing works
The Effects of Eight Weeks of Circuit Resistance Training on Serum METRNL Levels and Insulin Resistance in Individuals with Type 2 Diabetes
Tayebi, S. M., Golmohammadi, M., Eslami, R., Shakiba, N., & Costa, P. B. (2023) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-023-01225-1 · Cited by 23 · see citing works

Authors: Dunstan, D. W., Daly, R. M., Owen, N., Jolley, D., de Courten, M., Shaw, J., & Zimmet, P.
Affiliations: International Diabetes Institute, Melbourne, Australia
Deakin University (AU)
The University of Queensland (AU)
ORCID: Dunstan, David W.
Daly, Robin M.
Owen, Neville
Shaw, Jonathan
Zimmet, Paul
Venue: Diabetes Care
Publisher: American Diabetes Association
Published: 2002-10-01
Volume: 25
Issue: 10
Pages: 1729-1736
ISSN: 0149-5992 (ISSN-L)
1935-5548
DOI: 10.2337/diacare.25.10.1729
OpenAlex: W2111388675
Cited by: 771
References: 43
Citations by year: 2026: 20 · 2025: 28 · 2024: 27 · 2023: 34 · 2022: 24 · 2021: 28 · 2020: 23 · 2019: 23 · 2018: 29 · 2017: 35 · 2016: 22 · 2015: 40 · 2014: 51 · 2013: 33 · 2012: 37
FWCI: 5.93
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Diabetes Care (publishedVersion)
PubMed (publishedVersion)
Victoria University Research Repository (Victoria University) (submittedVersion)
Research Bank (Australian Catholic University) (submittedVersion)
Deakin Research Online (Deakin University) (submittedVersion)
Topics: Health Sciences › Medicine › Physiology › Physical Activity and Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: high-intensity resistance training, type 2 diabetes, older adults, glycemic control, HbA1c, weight loss, body composition, lean body mass, fat mass
MeSH terms: Adipose Tissue, Age Factors, Aged, Blood Glucose, Body Height, Body Weight, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diet, Diabetic, Female, Glycated Hemoglobin, Humans, Male, Middle Aged, Obesity, Exercise, Body Mass Index

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

High-intensity resistance training improves glycemic control in older patients with type 2 diabetes

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks