Cited by 491Treatment of Major DepressionNeural and Behavioral Psychology StudiesAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cognitive functioning in major depression – a summary

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Hammar, Åsa·2009·Frontiers in Human Neuroscience

Abstract

The aim of the present paper is to summarize the research during the past decade regarding cognitive functioning in Major Depressive Disorder (MDD). Cognitive impairment in the acute phase of illness has been frequently reported. The findings are shown in different cognitive domains, such as executive functions, attention, memory and psychomotor speed. Fewer reports have investigated cognitive functioning in MDD in longitudinal studies. Some longitudinal reports show that the impairment observed in the acute phase of illness may be long lasting despite symptom reduction and recovery. However, findings regarding cognitive functioning in depression are divergent. Factors that might contribute to the divergent findings, such as depression subtype, severity and comorbidity are discussed. Clinical implications and focus of future research directions is highlighted.In conclusion, depression is associated with cognitive impairment in the acute phase of illness, and some reports indicate that this impairment might be long lasting despite symptom reduction and recovery.

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Crossref · 10.3389/neuro.09.026.2009

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  1. Rush A. J. (2001). Chronic major depression: a review and update. J. Clin. Psychiatry 62(Suppl. 6), 3– 4

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Authors
Hammar, Å.
Affiliations
Haukeland University Hospital (NO)
Corresponding author
Hammar, Åsa
Venue
Frontiers in Human Neuroscience
Published
2009
Volume
3
Pages
26-26
ISSN
1662-5161 (ISSN-L)
OpenAlex
W2091523152
Cited by
491
References
81
Citations by year
2026: 16 · 2025: 19 · 2024: 25 · 2023: 31 · 2022: 40 · 2021: 35 · 2020: 31 · 2019: 53 · 2018: 43 · 2017: 46 · 2016: 36 · 2015: 26 · 2014: 23 · 2013: 19 · 2012: 17
FWCI
11.26
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Human Neuroscience (publishedVersion, cc-by)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
major depressive disorder, cognitive impairment, executive function, attention, memory, psychomotor speed, depression subtypes, depression severity, comorbidities, recovery from depression

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