Microalgae Produce Antioxidant Molecules with Potential Preventive Effects on Mitochondrial Functions and Skeletal Muscular Oxidative Stress

Vignaud, Jordi; Loiseau, Céline; Hérault, Josiane; Mayer, Claire; Côme, Martine; Martin, Isabelle; Ulmann, Lionel

doi:10.3390/antiox12051050

Cited by 72Exercise and Physiological ResponsesMuscle Physiology and DisordersSeaweed-derived Bioactive Compounds

Microalgae Produce Antioxidant Molecules with Potential Preventive Effects on Mitochondrial Functions and Skeletal Muscular Oxidative Stress

Open access

Vignaud, Jordi, Loiseau, Céline, Hérault, Josiane, Mayer, Claire, Côme, Martine, Martin, Isabelle, Ulmann, Lionel·2023·Antioxidants

DOI 10.3390/antiox12051050PMC PMC10215861

Open this paper in CoChat — free account Open PDF

Abstract

In recent years, microalgae have become a source of molecules for a healthy life. Their composition of carbohydrates, peptides, lipids, vitamins and carotenoids makes them a promising new source of antioxidant molecules. Skeletal muscle is a tissue that requires constant remodeling via protein turnover, and its regular functioning consumes energy in the form of adenosine triphosphate (ATP), which is produced by mitochondria. Under conditions of traumatic exercise or muscular diseases, a high production of reactive oxygen species (ROS) at the origin of oxidative stress (OS) will lead to inflammation and muscle atrophy, with life-long consequences. In this review, we describe the potential antioxidant effects of microalgae and their biomolecules on mitochondrial functions and skeletal muscular oxidative stress during exercises or in musculoskeletal diseases, as in sarcopenia, chronic obstructive pulmonary disease (COPD) and Duchenne muscular dystrophy (DMD), through the increase in and regulation of antioxidant pathways and protein synthesis.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.3390/antiox12051050

Cites

215 of 215 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Microalgae may protect mitochondrial function and muscle tissue from oxidative damage, offering benefits for ageing populations and individuals with metabolic or muscular disorders.
“Finally, novel evidence suggests that microalgae may protect mitochondrial function and muscle tissue from oxidative damage, offering benefits for ageing populations and individuals with metabolic or muscular disorders [47].”
From Microalgae Bioactives for Functional Food Innovation and Health Promotion (2025) · cites this paper as [47]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Sarcopenia: revised European consensus on definition and diagnosis
Cruz-Jentoft, A. J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., Cooper, C., Landi, F., Rolland, Y., Sayer, A. A., et al. (2019) · Age and Ageing · doi:10.1093/ageing/afy169 · Cited by 13,818 · see citing works
Sarcopenia: European consensus on definition and diagnosis
Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601 · see citing works
NF-κB signaling in inflammation
Liu, T., Zhang, L., Joo, D., & Sun, S.-C. (2017) · Signal Transduction and Targeted Therapy · doi:10.1038/sigtrans.2017.23 · Cited by 8,791 · see citing works
Development by Self-Digestion
Levine, B., & Klionsky, D. J. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00099-1 · Cited by 3,672 · see citing works
The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
Juan, C. A., Pérez de la Lastra, J. M., Plou, F. J., & Pérez-Lebeña, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094642 · Cited by 2,810 · see citing works
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
Bodine, S. C., Stitt, T. N., Gonzalez, M., Kline, W. O., Stover, G. L., Bauerlein, R., Zlotchenko, E., Scrimgeour, A., Lawrence, J. C., Glass, D. J., et al. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1014 · Cited by 2,752 · see citing works
Mitochondria as multifaceted regulators of cell death
Bock, F. J., & Tait, S. W. G. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0173-8 · Cited by 2,482 · see citing works
The anti-inflammatory effects of exercise: Mechanisms and implications for the prevention and treatment of disease
Gleeson, M., Bishop, N. C., Stensel, D. J., Lindley, M. R., Mastana, S. S., & Nimmo, M. A. (2011) · Nature Reviews Immunology · doi:10.1038/nri3041 · Cited by 2,470 · see citing works
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
Powers, S. K., & Jackson, M. J. (2008) · Physiological Reviews · doi:10.1152/physrev.00031.2007 · Cited by 2,459 · see citing works
Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
Hosokawa, N., Hara, T., Kaizuka, T., Kishi, C., Takamura, A., Miura, Y., Iemura, S.-I., Natsume, T., Takehana, K., Yamada, N., et al. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1248 · Cited by 2,076 · see citing works
Sarcopenia: Aging-Related Loss of Muscle Mass and Function
Larsson, L., Degens, H., Li, M., Salviati, L., Lee, Y. I., Thompson, W., Kirkland, J. L., & Sandri, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00061.2017 · Cited by 1,797 · see citing works
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways
Rommel, C., Bodine, S. C., Clarke, B. A., Rossman, R., Nunez, L., Stitt, T. N., Yancopoulos, G. D., & Glass, D. J. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1009 · Cited by 1,583 · see citing works
Autophagy is required to maintain muscle mass.
Masiero, E., Agatea, L., Mammucari, C., Blaauw, B., Loro, E., Komatsu, M., Metzger, D., Reggiani, C., Schiaffino, S., & Sandri, M. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.10.008 · Cited by 1,282 · see citing works
Effects of Long-term Vitamin E Supplementation on Cardiovascular Events and Cancer: A Randomized Controlled Trial
(2005) · JAMA · doi:10.1001/jama.293.11.1338 · Cited by 1,209 · cited 1× · see citing works
“However, studies report that long-term vitamin E supplementation may increase the risk of heart failure in patients with vascular disease or diabetes mellitus [100].”
Background
Diagnosis and management of Duchenne muscular dystrophy, part 2: implementation of multidisciplinary care
Bushby, K. M. D., Finkel, R. S., Birnkrant, D. J., Case, L. E., Clemens, P. R., Cripe, L. H., Kaul, A., Kinnett, K., McDonald, C. M., Pandya, S., et al. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70272-8 · Cited by 1,175 · see citing works
Physiology of Nitric Oxide in Skeletal Muscle
Stamler, J. S., & Meissner, G. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.209 · Cited by 1,080 · see citing works
Exercise induces transient transcriptional activation of the PGC‐1α gene in human skeletal muscle
Pilegaard, H., Saltin, B., & Neufer, P. D. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2002.034850 · Cited by 885 · see citing works
Microalgae Metabolites: A Rich Source for Food and Medicine
Sathasivam, R., Radhakrishnan, R., Hashem, A., & Abd_Allah, E. F. (2019) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2017.11.003 · Cited by 872 · see citing works
Regulation and metabolic functions of mTORC1 and mTORC2.
Szwed, A., Kim, E., & Jacinto, E. (2021) · Physiological Reviews · doi:10.1152/physrev.00026.2020 · Cited by 723 · see citing works
Methods for Monitoring Autophagy from Yeast to Human
Klionsky, D. J., Cuervo, A. M., & Seglen, P. O. (2007) · Autophagy · doi:10.4161/auto.3678 · Cited by 656 · see citing works
Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review
Li, C., Yu, K., Shyh‐Chang, N., Jiang, Z., Liu, T., Ma, S., Luo, L., Guang, L., Liang, K., Ma, W., et al. (2022) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12901 · Cited by 626 · see citing works
Physical exercise in the prevention and treatment of Alzheimer's disease
la Rosa, A. D., González, G. O., Arc‐Chagnaud, C., Millán-Domingo, F., Salvador‐Pascual, A., García-Lucerga, C., Blasco-Lafarga, C., García-Domínguez, E., Carretero, A., Correas, Á. G., et al. (2020) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2020.01.004 · Cited by 617 · see citing works
Oxidative stress and vascular inflammation in aging
Assar, M. E., Angulo, J., & Rodríguez‐Mañas, L. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.07.003 · Cited by 576 · see citing works
Mitochondria as playmakers of apoptosis, autophagy and senescence
Abate, M., Festa, A., Falco, M., Lombardi, A., Luce, A., Grimaldi, A., Zappavigna, S., Sperlongano, P., Irace, C., Caraglia, M., et al. (2019) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2019.05.022 · Cited by 543 · see citing works
The Effects of Exercise and Physical Activity on Weight Loss and Maintenance
Swift, D. L., McGee, J. E., Earnest, C. P., Carlisle, E., Nygard, M., & Johannsen, N. M. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.07.014 · Cited by 536 · see citing works
Signalling to translation: How signal transduction pathways control the protein synthetic machinery
Proud, C. G. (2007) · Biochemical Journal · doi:10.1042/bj20070024 · Cited by 520 · see citing works
Fish oil–derived n−3 PUFA therapy increases muscle mass and function in healthy older adults
Smith, G. I., Julliand, S., Reeds, D. N., Sinacore, D. R., Klein, S., & Mittendorfer, B. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.105833 · Cited by 507 · see citing works
The prevalence of quadriceps weakness in COPD and the relationship with disease severity
Seymour, J. M., Spruit, M. A., Hopkinson, N. S., Natanek, S. A., Man, W. D., Jackson, A., Gosker, H. R., Schols, A. M. W. J., Moxham, J., Polkey, M. I., et al. (2009) · European Respiratory Journal · doi:10.1183/09031936.00104909 · Cited by 498 · see citing works
Protein damage and degradation by oxygen radicals. IV. Degradation of denatured protein.
Davies, K. J. A., Lin, S. W., & Pacifici, R. E. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48021-0 · Cited by 480 · see citing works
mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
Zhao, J., Zhai, B., Gygi, S. P., & Goldberg, A. L. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1521919112 · Cited by 471 · see citing works
Mitochondrial function and apoptotic susceptibility in aging skeletal muscle
Chabi, B., Ljubicic, V., Menzies, K. J., Huang, J. H., Saleem, A., & Hood, D. A. (2008) · Aging Cell · doi:10.1111/j.1474-9726.2007.00347.x · Cited by 437 · see citing works
Physical activity and modulation of systemic low-level inflammation
Bruunsgaard, H. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.0505247 · Cited by 429 · see citing works
Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca 2+ , Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy
Allen, D. G., Whitehead, N. P., & Froehner, S. C. (2015) · Physiological Reviews · doi:10.1152/physrev.00007.2015 · Cited by 422 · see citing works
Global Translational Responses to Oxidative Stress Impact upon Multiple Levels of Protein Synthesis
Shenton, D., Smirnova, J. B., Selley, J. N., Carroll, K. M., Hubbard, S. J., Pavitt, G. D., Ashe, M., & Grant, C. M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601545200 · Cited by 417 · see citing works
Vitamin E Regulatory Mechanisms
Traber, M. G. (2007) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.27.061406.093819 · Cited by 414 · see citing works
Ubiquitination-Proteasome System (UPS) and Autophagy Two Main Protein Degradation Machineries in Response to Cell Stress
Li, Y., Li, S., & Wu, H. (2022) · Cells · doi:10.3390/cells11050851 · Cited by 384 · see citing works
Influence of exercise and fiber type on antioxidant enzyme activity in rat skeletal muscle
Powers, S. K., Criswell, D. S., Lawler, J., Ji, L. L., Martin, D., Herb, R. A., & Dudley, G. (1994) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1994.266.2.r375 · Cited by 379 · see citing works
Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia-hyperaminoacidaemia in healthy young and middle-aged men and women
Smith, G. I., Atherton, P., Reeds, D. N., Mohammed, B. S., Rankin, D., Rennie, M. J., & Mittendorfer, B. (2011) · Clinical Science · doi:10.1042/cs20100597 · Cited by 372 · see citing works
Physical activity and exercise as countermeasures to physical frailty and sarcopenia
on behalf of the SPRINTT Consortium, Marzetti, E., Calvani, R., Tosato, M., Cesari, M., Di Bari, M., Cherubini, A., Broccatelli, M., Savera, G., D’Elia, M., et al. (2017) · Aging Clinical and Experimental Research · doi:10.1007/s40520-016-0705-4 · Cited by 362 · see citing works
Nutrition and Sarcopenia—What Do We Know?
Ganapathy, A., & Nieves, J. W. (2020) · Nutrients · doi:10.3390/nu12061755 · Cited by 355 · see citing works
Duchenne muscular dystrophy
Yiu, E. M., & Kornberg, A. J. (2015) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.12868 · Cited by 336 · see citing works
Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: a double‐blind, randomised, controlled trial
Paulsen, G., Cumming, K. T., Holden, G., Hallén, J., Rønnestad, B. R., Sveen, O., Skaug, A., Paur, I., Bastani, N. E., Østgaard, H. N., et al. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2013.267419 · Cited by 333 · see citing works
Do antioxidant supplements interfere with skeletal muscle adaptation to exercise training?
Merry, T. L., & Ristow, M. (2015) · The Journal of Physiology · doi:10.1113/jp270654 · Cited by 326 · see citing works
Omega-3 Polyunsaturated Fatty Acids: Benefits and Endpoints in Sport
Gammone, M. A., Riccioni, G., Parrinello, G., & D’Orazio, N. (2018) · Nutrients · doi:10.3390/nu11010046 · Cited by 326 · see citing works
NF-kB and Inflammatory Cytokine Signalling: Role in Skeletal Muscle Atrophy
Thoma, A., & Lightfoot, A. P. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-1435-3_12 · Cited by 320 · see citing works
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance
Lee, H.-Y., Choi, C. S., Birkenfeld, A. L., Alves, T. C., Jornayvaz, F. R., Jurczak, M. J., Zhang, D., Woo, D. K., Shadel, G. S., Ladiges, W., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.11.004 · Cited by 319 · see citing works
Exercise-Induced Oxidative Stress and the Effects of Antioxidant Intake from a Physiological Viewpoint
Kawamura, T., & Muraoka, I. (2018) · Antioxidants · doi:10.3390/antiox7090119 · Cited by 314 · see citing works
Duchenne Muscular Dystrophy: From Diagnosis to Therapy
Falzarano, M. S., Scotton, C., Passarelli, C., & Ferlini, A. (2015) · Molecules · doi:10.3390/molecules201018168 · Cited by 293 · see citing works
Nutrition and Supplement Update for the Endurance Athlete: Review and Recommendations
Vitale, K., & Getzin, A. R. (2019) · Nutrients · doi:10.3390/nu11061289 · Cited by 290 · see citing works
4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle
Shah, O. J., Anthony, J. C., Kimball, S. R., & Jefferson, L. S. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.4.e715 · Cited by 286 · see citing works
Analysis of cellular responses to free radicals: focus on exercise and skeletal muscle
Powers, S. K., & Lennon, S. L. (1999) · Proceedings of The Nutrition Society · doi:10.1017/s0029665199001342 · Cited by 284 · see citing works
Antioxidant Compounds from Microalgae: A Review
Coulombier, N., Jauffrais, T., & Lebouvier, N. (2021) · Marine Drugs · doi:10.3390/md19100549 · Cited by 277 · see citing works
Oxidative stress during exercise: Implication of antioxidant nutrients
Ji, L. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00212-3 · Cited by 276 · see citing works
Microalgae Biotechnology for Food, Health and High Value Products
(2020) · Springer eBooks · doi:10.1007/978-981-15-0169-2 · Cited by 272 · see citing works
The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration
Thomson, D. M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103125 · Cited by 267 · cited 1× · see citing works
“In contrast, during muscle disease associated with mitochondrial dysfunction, AMPK suppresses the MPS via an inhibition of mTORC1 [49].”
Background
Microalgae Characterization for Consolidated and New Application in Human Food, Animal Feed and Nutraceuticals
Molino, A., Iovine, A., Casella, P., Mehariya, S., Chianese, S., Cerbone, A., Rimauro, J., & Musmarra, D. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15112436 · Cited by 263 · see citing works
Microalgae: therapeutic potentials and applications
Khavari, F., Saidijam, M., Taheri‬, M., & Nouri, F. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06422-w · Cited by 259 · see citing works
Adaptations of glutathione antioxidant system to endurance training are tissue and muscle fiber specific
Leeuwenburgh, C., Hollander, J., Leichtweis, S. B., Griffiths, M. A., Gore, M. T., & Ji, L. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.272.1.r363 · Cited by 250 · see citing works
Muscle Atrophy and Hypertrophy Signaling in Patients with Chronic Obstructive Pulmonary Disease
Doucet, M., Russell, A. P., Léger, B., Debigaré, R., Joanisse, D. R., Caron, M.-A., LeBlanc, P., & Maltais, F. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200605-704oc · Cited by 243 · see citing works
The Influence of Omega-3 Fatty Acids on Skeletal Muscle Protein Turnover in Health, Disuse, and Disease
McGlory, C., Calder, P. C., & Nunes, E. A. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00144 · Cited by 228 · see citing works
Lysosome: regulator of lipid degradation pathways
Settembre, C., & Ballabio, A. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.06.006 · Cited by 225 · see citing works
Challenging microalgal vitamins for human health
Del Mondo, A., Smerilli, A., Sané, E., Sansone, C., & Brunet, C. (2020) · Microbial Cell Factories · doi:10.1186/s12934-020-01459-1 · Cited by 220 · see citing works
Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle
Clavel, S., Coldefy, A.-S., Kurkdjian, E., Salles, J., Margaritis, I., & Dérijard, B. (2006) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.07.005 · Cited by 218 · see citing works
Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults
Safdar, A., Hamadeh, M. J., Kaczor, J. J., Raha, S., deBeer, J., & Tarnopolsky, M. A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010778 · Cited by 217 · see citing works
Microalgae n-3 PUFAs Production and Use in Food and Feed Industries
Remize, M., Brunel, Y., Silva, J. L., Berthon, J.-Y., & Filaire, E. (2021) · Marine Drugs · doi:10.3390/md19020113 · Cited by 214 · see citing works
Functional Properties of Carotenoids in Human Health
Perera, C. O., & Yen, G. M. (2007) · International Journal of Food Properties · doi:10.1080/10942910601045271 · Cited by 209 · see citing works
The role of omega-3 in the prevention and treatment of sarcopenia
Dupont, J., Dedeyne, L., Dalle, S., Koppo, K., & Gielen, E. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-019-01146-1 · Cited by 208 · see citing works
Omega-3 Fatty Acids and Skeletal Muscle Health
Jeromson, S., Gallagher, I., Galloway, S., & Hamilton, D. (2015) · Marine Drugs · doi:10.3390/md13116977 · Cited by 203 · see citing works
Mechanistic Links Between Oxidative Stress and Disuse Muscle Atrophy
Powers, S. K., Smuder, A. J., & Criswell, D. S. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2011.3973 · Cited by 199 · see citing works
Cellular Markers of Muscle Atrophy in Chronic Obstructive Pulmonary Disease
Plant, P. J., Brooks, D., Faughnan, M., Bayley, T., Bain, J., Singer, L., Correa, J., Pearce, D., Binnie, M., & Batt, J. (2010) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2008-0382oc · Cited by 190 · see citing works
Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress
Suzuki, K., Tominaga, T., Ruhee, R. T., & Ma, S. (2020) · Antioxidants · doi:10.3390/antiox9050401 · Cited by 190 · see citing works
Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification
Aoi, W., Naito, Y., Takanami, Y., Ishii, T., Kawai, Y., Akagiri, S., Kato, Y., Osawa, T., & Yoshikawa, T. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.12.019 · Cited by 179 · see citing works
Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone
Timoshnikov, V. A., Kobzeva, T. V., Polyakov, N. E., & Kontoghiorghes, G. J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21113967 · Cited by 178 · see citing works
Exercise-Stimulated ROS Sensitive Signaling Pathways in Skeletal Muscle
Bouvière, J., Fortunato, R. S., Dupuy, C., Werneck‐de‐Castro, J. P., de Carvalho, D. P., & Louzada, R. A. N. (2021) · Antioxidants · doi:10.3390/antiox10040537 · Cited by 175 · see citing works
Effect of pulmonary rehabilitation on muscle remodelling in cachectic patients with COPD
Vogiatzis, I., Simoes, D. C. M., Stratakos, G. K., Kourepini, E., Terzis, G. D., Manta, P., Athanasopoulos, D., Roussos, C., Wagner, P. D., & Zakynthinos, S. G. (2010) · European Respiratory Journal · doi:10.1183/09031936.00112909 · Cited by 173 · see citing works
Reduced mitochondrial density in the vastus lateralis muscle of patients with COPD
Gosker, H. R., Hesselink, M. K. C., Duimel, H., Ward, K., & Schols, A. M. W. J. (2007) · European Respiratory Journal · doi:10.1183/09031936.00146906 · Cited by 172 · see citing works
Biomolecules from Microalgae and Cyanobacteria: Applications and Market Survey
Hachicha, R., Elleuch, F., Hlima, H. B., Dubessay, P., de Baynast, H., Delattre, C., Pierre, G., Hachicha, R., Abdelkafi, S., Michaud, P., et al. (2022) · Applied Sciences · doi:10.3390/app12041924 · Cited by 172 · see citing works
Oxidative Stress, Redox Signaling Pathways, and Autophagy in Cachectic Muscles of Male Patients with Advanced COPD and Lung Cancer
Puig-Vilanova, E., Rodriguez, D. A., Lloreta, J., Ausin, P., Pascual-Guardia, S., Broquetas, J., Roca, J., Gea, J., & Barreiro, E. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.11.006 · Cited by 167 · see citing works
Pitfalls in the analysis of the physiological antioxidant glutathione (GSH) and its disulfide (GSSG) in biological samples: An elephant in the room
Giustarini, D., Tsikas, D., Colombo, G., Milzani, A., Dalle‐Donne, I., Fanti, P., & Rossi, R. (2016) · Journal of Chromatography B · doi:10.1016/j.jchromb.2016.02.015 · Cited by 163 · see citing works
Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults
Lalia, A. Z., Dasari, S., Robinson, M. M., Abid, H., Morse, D. M., Klaus, K. A., & Lanza, I. R. (2017) · Aging · doi:10.18632/aging.101210 · Cited by 163 · see citing works
Antioxidant and Adaptative Response Mediated by Nrf2 during Physical Exercise
Vargas-Mendoza, N., Morales‐González, Á., Madrigal‐Santillán, E., Madrigal‐Bujaidar, E., Álvarez‐González, I., García-Melo, L. F., Anguiano‐Robledo, L., Fregoso-Aguilar, T. A., & Morales‐González, J. A. (2019) · Antioxidants · doi:10.3390/antiox8060196 · Cited by 163 · see citing works
Skeletal muscle proteolysis in aging
Combaret, L., Dardevet, D. P., Béchet, D., Taillandier, D., Mosoni, L., & Attaix, D. (2008) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e32831b9c31 · Cited by 152 · see citing works
A review on role of fish in human nutrition with special emphasis to essential fatty acid
Pal, J., Shukla, B., Maurya, A. K., Verma, H. O., Pandey, G., & Amitha (2018) · International Journal of Fisheries and Aquatic Studies · Cited by 151 · see citing works
Extracellular superoxide dismutase, a molecular transducer of health benefits of exercise
Yan, Z., & Spaulding, H. R. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101508 · Cited by 150 · see citing works
The role of raptor in the mechanical load‐induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy
You, J.-S., Mcnally, R. M., Jacobs, B. L., Privett, R. E., Gundermann, D. M., Lin, K.-H., Steinert, N. D., Goodman, C. A., & Hornberger, T. A. (2019) · The FASEB Journal · doi:10.1096/fj.201801653rr · Cited by 149 · see citing works
Long-Term Supplementation With Resveratrol Alleviates Oxidative Stress but Does Not Attenuate Sarcopenia in Aged Mice
Jackson, J. R., Ryan, M. J., & Alway, S. E. (2011) · The Journals of Gerontology Series A · doi:10.1093/gerona/glr047 · Cited by 145 · see citing works
Brown Algae as Functional Food Source of Fucoxanthin: A Review
Din, N. A. S., Alayudin, ‘. S. M., Sofian‐Seng, N., Rahman, H. A., Razali, N. S. M., Lim, S. J., & Mustapha, W. A. W. (2022) · Foods · doi:10.3390/foods11152235 · Cited by 139 · see citing works
Vitamin E: Regulatory Role on Signal Transduction
Zingg, J.-M. A. (2018) · IUBMB Life · doi:10.1002/iub.1986 · Cited by 136 · see citing works
Promises and Challenges of Microalgal Antioxidant Production
Sansone, C., & Brunet, C. (2019) · Antioxidants · doi:10.3390/antiox8070199 · Cited by 136 · see citing works
Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet
Lanza, I. R., Blachnio-Zabielska, A., Johnson, M. L., Schimke, J. M., Jakaitis, D. R., Lebrasseur, N. K., Jensen, M. D., Sreekumaran Nair, K., & Zabielski, P. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00584.2012 · Cited by 135 · see citing works
Unconventional high-value products from microalgae: A review
Abu‐Ghosh, S., Dubinsky, Z., Verdelho, V., & Iluz, D. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.124895 · Cited by 135 · see citing works
An Update on Protein, Leucine, Omega-3 Fatty Acids, and Vitamin D in the Prevention and Treatment of Sarcopenia and Functional Decline
Tessier, A., & Chevalier, S. (2018) · Nutrients · doi:10.3390/nu10081099 · Cited by 132 · see citing works
Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress
Grounds, M. D., Terrill, J. R., Al-Mshhdani, B. A., Duong, M. N., Radley‐Crabb, H. G., & Arthur, P. G. (2020) · Disease Models & Mechanisms · doi:10.1242/dmm.043638 · Cited by 132 · see citing works
Resveratrol Protects against Physical Fatigue and Improves Exercise Performance in Mice
Wu, R.-E., Huang, W.-C., Liao, C.-C., Chang, Y., Kan, N., & Huang, C. (2013) · Molecules · doi:10.3390/molecules18044689 · Cited by 131 · see citing works
Redox basis of exercise physiology
Margaritelis, N. V., Paschalis, V., Theodorou, A. A., Kyparos, A., & Nikolaidis, M. G. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101499 · Cited by 129 · see citing works
The mammalian target of rapamycin-signaling pathway in regulating metabolism and growth1,2
Yang, X., Yang, C. B., Farberman, A., Rideout, T. C., de Lange, C. F. M., France, J., & Fan, M. Z. (2007) · Journal of Animal Science · doi:10.2527/jas.2007-0567 · Cited by 128 · see citing works
MUSCLE DISUSE AS A PIVOTAL PROBLEM IN SARCOPENIA-RELATED MUSCLE LOSS AND DYSFUNCTION
Bell, K. E., von Allmen, M., Devries, M. C., & Phillips, S. M. (2016) · The Journal of Frailty & Aging · doi:10.14283/jfa.2016.78 · Cited by 127 · see citing works
Nutraceutical characteristics of the brown seaweed carotenoid fucoxanthin
Miyashita, K., Beppu, F., Hosokawa, M., Liu, X., & Wang, S. (2020) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108364 · Cited by 127 · see citing works
Diatoms as cell factories for high-value products: chrysolaminarin, eicosapentaenoic acid, and fucoxanthin
Yang, R., Wei, D., & Xie, J. (2020) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2020.1805402 · Cited by 124 · see citing works
Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention
Le Goff, M., Le Ferrec, E., Mayer, C., Mimouni, V., Lagadic-Gossmann, D., Schoefs, B., & Ulmann, L. (2019) · Biochimie · doi:10.1016/j.biochi.2019.09.012 · Cited by 123 · see citing works
Self-citation
Loss of quadriceps muscle oxidative phenotype and decreased endurance in patients with mild-to-moderate COPD
van den Borst, B., Slot, I. G. M., Hellwig, V. A. C. V., Vosse, B. A. H., KELDERS, M. C. J. M., Barreiro, E., Schols, A. M. W. J., & Gosker, H. R. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00508.2012 · Cited by 120 · see citing works
High production of carotenoids by the green microalga Asterarcys quadricellulare PUMCC 5.1.1 under optimized culture conditions
Singh, D. P., Khattar, J. S., Rajput, A., Chaudhary, R., & Singh, R. (2019) · PLoS ONE · doi:10.1371/journal.pone.0221930 · Cited by 120 · see citing works
Biological Properties and Health-Promoting Functions of Laminarin: A Comprehensive Review of Preclinical and Clinical Studies
Shanmugapriya, K., Rajauria, G., Fitzpatrick, S., Lyons, H., McMahon, H. P., Curtin, J. F., Tiwari, B. K., & O’Donnell, C. P. (2022) · Marine Drugs · doi:10.3390/md20120772 · Cited by 120 · see citing works
Mitochondrial ROS and mitochondria-targeted antioxidants in the aged heart
Bou‐Teen, D., Kaludercic, N., Weissman, D., Turan, B., Maack, C., Lisa, F. D., & Ruiz‐Meana, M. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.02.043 · Cited by 119 · see citing works
Value of Resistance Training for the Reduction of Sports Injuries
Fleck, S. J., & Falkel, J. E. (1986) · Sports Medicine · doi:10.2165/00007256-198603010-00006 · Cited by 117 · see citing works
Autophagy in Locomotor Muscles of Patients with Chronic Obstructive Pulmonary Disease
Guo, Y., Gosker, H. R., Schols, A. M. W. J., Kapchinsky, S., Bourbeau, J., Sandri, M., Jagoe, R. T., Debigaré, R., Maltais, F., Taivassalo, T., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201304-0732oc · Cited by 117 · see citing works
The role of AMP-activated protein kinase in the coordination of skeletal muscle turnover and energy homeostasis
Sanchez, A. M. J., Candau, R. B., Csibi, A., Pagano, A. F., Raibon, A., & Bernardi, H. (2012) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00125.2012 · Cited by 116 · see citing works
Sports foods and dietary supplements for optimal function and performance enhancement in track-and-field athletes
Peeling, P., Castell, L. M., Derave, W., de Hon, O., & Burke, L. M. (2019) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2018-0271 · Cited by 116 · see citing works
Dual Role of Reactive Oxygen Species in Muscle Function: Can Antioxidant Dietary Supplements Counteract Age-Related Sarcopenia?
Damiano, S., Muscariello, E., Rosa, G. L., Maro, M. D., Mondola, P., & Santillo, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20153815 · Cited by 110 · see citing works
The effect of eicosapentaenoic and docosahexaenoic acid on protein synthesis and breakdown in murine C2C12 myotubes
Kamolrat, T., & Gray, S. R. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.02.041 · Cited by 108 · see citing works
Marine Bacteria versus Microalgae: Who Is the Best for Biotechnological Production of Bioactive Compounds with Antioxidant Properties and Other Biological Applications?
Hamidi, M., Kozani, P. S., Kozani, P. S., Pierre, G., Michaud, P., & Delattre, C. (2019) · Marine Drugs · doi:10.3390/md18010028 · Cited by 107 · see citing works
Fucoxanthin promotes translocation and induction of glucose transporter 4 in skeletal muscles of diabetic/obese KK-A mice
Nishikawa, S., Hosokawa, M., & Miyashita, K. (2012) · Phytomedicine · doi:10.1016/j.phymed.2011.11.001 · Cited by 103 · see citing works
Gallic Acid and Gallates in Human Health and Disease: Do Mitochondria Hold the Key to Success?
Kosuru, R. Y., Roy, A., Das, S. K., & Bera, S. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201700699 · Cited by 103 · see citing works
Quadriceps Fatigue After Cycle Exercise in Patients With COPD Compared With Healthy Control Subjects
Mador, M. J., Bozkanat, E., & Kufel, T. J. (2003) · CHEST Journal · doi:10.1378/chest.123.4.1104 · Cited by 99 · see citing works
The Effect of a 12-Week Omega-3 Supplementation on Body Composition, Muscle Strength and Physical Performance in Elderly Individuals with Decreased Muscle Mass
Krzymińska-Siemaszko, R., Czepulis, N., Lewandowicz, M., Zasadzka, E., Suwalska, A., Witowski, J., & Wieczorowska–Tobis, K. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph120910558 · Cited by 99 · see citing works
The Mitochondrial Phenotype of Peripheral Muscle in Chronic Obstructive Pulmonary Disease
Picard, M., Godin, R., Sinnreich, M., Baril, J., Bourbeau, J., Perrault, H., Taivassalo, T., & Burelle, Y. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200807-1005oc · Cited by 95 · see citing works
Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice
Ryan, M. J., Jackson, J. R., Hao, Y., Leonard, S. S., & Alway, S. E. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.04.002 · Cited by 94 · see citing works
Contribution of oxidative stress to pathology in diaphragm and limb muscles with Duchenne muscular dystrophy
Kim, J. H., Kwak, H., Thompson, L. V., & Lawler, J. M. (2012) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-012-9330-9 · Cited by 94 · see citing works
Autophagy, apoptosis, and mitochondria: molecular integration and physiological relevance in skeletal muscle
Bloemberg, D., & Quadrilatero, J. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00261.2018 · Cited by 93 · see citing works
Producing fucoxanthin from algae – Recent advances in cultivation strategies and downstream processing
Leong, Y. K., Chen, C., Varjani, S., & Chang, J. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.126170 · Cited by 91 · see citing works
Stress oxydant et pathologies humaines
Favier, A. E. (2006) · Annales Pharmaceutiques Françaises · doi:10.1016/s0003-4509(06)75334-2 · Cited by 87 · see citing works
Exploring Nordic microalgae as a potential novel source of antioxidant and bioactive compounds
Léon-Vaz, A., León, R., Vigara, J., & Funk, C. (2022) · New Biotechnology · doi:10.1016/j.nbt.2022.12.001 · Cited by 87 · see citing works
Abdominal muscle and quadriceps strength in chronic obstructive pulmonary disease
Man, W. D. (2005) · Thorax · doi:10.1136/thx.2005.040709 · Cited by 85 · see citing works
Antioxidants in Personalized Nutrition and Exercise
Margaritelis, N. V., Paschalis, V., Theodorou, A. A., Kyparos, A., & Nikolaidis, M. G. (2018) · Advances in Nutrition · doi:10.1093/advances/nmy052 · Cited by 84 · see citing works
Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia
Hepple, R. T., Qin, M., Nakamoto, H., & Goto, S. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90478.2008 · Cited by 83 · see citing works
Polyphenols and Their Potential Role in Preventing Skeletal Muscle Atrophy
Salucci, S., & Falcieri, E. (2020) · Nutrition Research · doi:10.1016/j.nutres.2019.11.004 · Cited by 83 · see citing works
Oxidative Stress, Mitochondrial Function and Adaptation to Exercise: New Perspectives in Nutrition
Vargas-Mendoza, N., Ángeles-Valencia, M., Morales‐González, Á., Madrigal‐Santillán, E., Morales-Martínez, M., Madrigal‐Bujaidar, E., Álvarez‐González, I., Gutiérrez‐Salinas, J., Esquivel-Chirino, C., Chamorro, G., et al. (2021) · Life · doi:10.3390/life11111269 · Cited by 83 · see citing works
Screening of microalgae for primary metabolites including β-glucans and the influence of nitrate starvation and irradiance on β-glucan production
Schulze, C., Wetzel, M., Reinhardt, J. K., Schmidt, M., Felten, L., & Mundt, S. (2016) · Journal of Applied Phycology · doi:10.1007/s10811-016-0812-9 · Cited by 79 · see citing works
The oleaginous astaxanthin-producing alga Chromochloris zofingiensis: potential from production to an emerging model for studying lipid metabolism and carotenogenesis
Zhang, Y., Ye, Y., Bai, F., & Liu, J. (2021) · Biotechnology for Biofuels · doi:10.1186/s13068-021-01969-z · Cited by 77 · see citing works
Effect of dietary n-3 PUFA supplementation on the muscle transcriptome in older adults
Yoshino, J., Smith, G. I., Kelly, S. C., Julliand, S., Reeds, D. N., & Mittendorfer, B. (2016) · Physiological Reports · doi:10.14814/phy2.12785 · Cited by 76 · see citing works
Fucoxanthin Production of Microalgae under Different Culture Factors: A Systematic Review
Khaw, Y. S., Yusoff, F. M., Tan, H. T., Mazli, N. A. I. N., Nazarudin, M. F., Shaharuddin, N. A., Omar, A. R., & Takahashi, K. (2022) · Marine Drugs · doi:10.3390/md20100592 · Cited by 74 · see citing works
Lower Dietary and Circulating Vitamin C in Middle- and Older-Aged Men and Women Are Associated with Lower Estimated Skeletal Muscle Mass
Lewis, L. N., Hayhoe, R. P., Mulligan, A. A., Luben, R. N., Khaw, K.-T., & Welch, A. A. (2020) · The Journal of Nutrition · doi:10.1093/jn/nxaa221 · Cited by 72 · see citing works
Dr. NO and Mr. Toxic – the versatile role of nitric oxide
Porrini, C., Ramarao, N., & Tran, S. (2019) · Biological Chemistry · doi:10.1515/hsz-2019-0368 · Cited by 70 · see citing works
Cross-Sectional Associations Between Dietary Antioxidant Vitamins C, E and Carotenoid Intakes and Sarcopenic Indices in Women Aged 18–79 Years
Welch, A. A., Jennings, A., Kelaiditi, E., Skinner, J. S., & Steves, C. J. (2019) · Calcified Tissue International · doi:10.1007/s00223-019-00641-x · Cited by 69 · see citing works
Fish oil-derived n-3 polyunsaturated fatty acids for the prevention and treatment of sarcopenia
Gray, S. R., & Mittendorfer, B. (2017) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000441 · Cited by 67 · see citing works
Laminarin Effects, a β-(1,3)-Glucan, on Skin Cell Inflammation and Oxidation
Ozanne, H., Toumi, H., Roubinet, B., Landemarre, L., Lespessailles, É., Daniellou, R., & Césaro, A. (2020) · Cosmetics · doi:10.3390/cosmetics7030066 · Cited by 66 · see citing works
Characterization of selected microalgae and cyanobacteria as sources of compounds with antioxidant capacity
Almendinger, M., Saalfrank, F., Rohn, S., Kurth, E., Springer, M., & Pleißner, D. (2020) · Algal Research · doi:10.1016/j.algal.2020.102168 · Cited by 66 · see citing works
Human muscle aging: ROS-mediated alterations in rectus abdominis and vastus lateralis muscles
Marzani, B., Felzani, G., Bellomo, R. G., Vecchiet, J., & Marzatico, F. (2005) · Experimental Gerontology · doi:10.1016/j.exger.2005.08.010 · Cited by 65 · see citing works
Structural and functional changes in the skeletal muscles of COPD patients: the "compartments" theory.
Gea, J., Orozco‐Levi, M., Barreiro, E., Ferrer, A., & Broquetas, J. M. (2001) · PubMed · Cited by 64 · see citing works
Loss of muscle mass is poorly reflected in grip strength performance in healthy young men
JOHNSON, M. J., FRIEDL, K. E., FRYKMAN, P. N., & MOORE, R. J. (1994) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199402000-00015 · Cited by 63 · see citing works
Vitamin C Deficiency Causes Muscle Atrophy and a Deterioration in Physical Performance
Takisawa, S., Funakoshi, T., Yatsu, T., Nagata, K., Aigaki, T., Machida, S., & Ishigami, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-41229-7 · Cited by 63 · see citing works
Effect of Long-Term Omega 3 Polyunsaturated Fatty Acid Supplementation with or without Multidomain Lifestyle Intervention on Muscle Strength in Older Adults: Secondary Analysis of the Multidomain Alzheimer Preventive Trial (MAPT)
Rolland, Y., Barreto, P. D. S., Maltais, M. L., Guyonnet, S., Cantet, C., Andrieu, S., & Vellas, B. J. (2019) · Nutrients · doi:10.3390/nu11081931 · Cited by 62 · see citing works
Supplementation with dietary ω‐3 mitigates immobilization‐induced reductions in skeletal muscle mitochondrial respiration in young women
Miotto, P. M., McGlory, C., Bahniwal, R., Kamal, M. J., Phillips, S. M., & Holloway, G. P. (2019) · The FASEB Journal · doi:10.1096/fj.201900095r · Cited by 61 · see citing works
Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy
Terrill, J. R., Duong, M. N., Turner, R., Guiner, C. L., Boyatzis, A. E., Kettle, A. J., Grounds, M. D., & Arthur, P. G. (2016) · Redox Biology · doi:10.1016/j.redox.2016.08.016 · Cited by 60 · see citing works
Microalgae as an alternative to oil crops for edible oils and animal feed
Fawcett, C. A., Senhorinho, G. N. A., Laamanen, C. A., & Scott, J. A. (2022) · Algal Research · doi:10.1016/j.algal.2022.102663 · Cited by 60 · see citing works
Antioxidants for preventing and reducing muscle soreness after exercise
Ranchordas, M. K., Rogerson, D., Soltani, H., & Costello, J. T. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009789.pub2 · Cited by 56 · see citing works
Role of n-3 fatty acids in muscle loss and myosteatosis
Ewaschuk, J. B., Al-Masud, A. A., & Mazurak, V. C. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2013-0423 · Cited by 55 · see citing works
Ganoderma lucidum polysaccharides supplementation attenuates exercise-induced oxidative stress in skeletal muscle of mice
Zhonghui, Z., Xiaowei, Z., & Fang, F. (2013) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2013.04.004 · Cited by 55 · see citing works
The effect of oral omega-3 polyunsaturated fatty acid supplementation on muscle maintenance and quality of life in patients with cancer: A systematic review and meta-analysis
Lam, C. N., Watt, A., Isenring, E. A., de van der Schueren, M. A. E., & van der Meij, B. S. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.04.031 · Cited by 55 · see citing works
Impacts of Fortifying Nile Tilapia (Oreochromis niloticus) Diet with Different Strains of Microalgae on Its Performance, Fillet Quality and Disease Resistance to Aeromonas hydrophila Considering the Interplay between Antioxidant and Inflammatory Response
Ibrahim, D., El-Hamid, M. I. A., Al-Zaban, M. I., ElHady, M., El-Azzouny, M. M., Feky, T. M. E., Sadik, G. M. A., Samy, O. M., Hamed, T. A., Albalwe, F. M., et al. (2022) · Antioxidants · doi:10.3390/antiox11112181 · Cited by 55 · see citing works
Astaxanthin Supplementation Delays Physical Exhaustion and Prevents Redox Imbalances in Plasma and Soleus Muscles of Wistar Rats
Polotow, T. G., Vardaris, C. V., Mihaliuc, A., Gonçalves, M., Pereira, B. J., Ganini, D., & Barros, M. P. (2014) · Nutrients · doi:10.3390/nu6125819 · Cited by 53 · see citing works
Resveratrol and exercise
Baltacı, S. B., Moğulkoç, R., & Baltacı, A. K. (2016) · Biomedical Reports · doi:10.3892/br.2016.777 · Cited by 53 · see citing works
Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1
Zhang, L., Kimball, S. R., Jefferson, L. S., & Shenberger, J. S. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.03.001 · Cited by 52 · see citing works
An Overview of Physical Exercise and Antioxidant Supplementation Influences on Skeletal Muscle Oxidative Stress
Taherkhani, S., Valaei, K., Arazi, H., & Suzuki, K. (2021) · Antioxidants · doi:10.3390/antiox10101528 · Cited by 52 · see citing works
Site of Mitochondrial Reactive Oxygen Species Production in Skeletal Muscle of Chronic Obstructive Pulmonary Disease and Its Relationship with Exercise Oxidative Stress
Puente-Maestu, L., Tejedor, A., Lázaro, A., de Miguel, J., ÁLvarez-Sala, L., González-Aragoneses, F., Simón, C., & Agustí, A. (2012) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2011-0382oc · Cited by 51 · see citing works
Astaxanthin Supplementation Does Not Augment Fat Use or Improve Endurance Performance
RES, P. T., Cermak, N. M., Stinkens, R., TOLLAKSON, T. J., Haenen, G. R. M. M., Bast, A., & van Loon, L. J. C. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31827fddc4 · Cited by 50 · see citing works
Organization of metabolic pathways in vastus lateralis of patients with chronic obstructive pulmonary disease
Green, H. J., Bombardier, É., Burnett, M., Iqbal, S., D’Arsigny, C. L., OʼDonnell, D., Ouyang, J., & Webb, K. A. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00167.2008 · Cited by 48 · see citing works
Effect of Eicosapentaenoic Acid and Docosahexaenoic Acid on Myogenesis and Mitochondrial Biosynthesis during Murine Skeletal Muscle Cell Differentiation
Hsueh, T., Baum, J., & Huang, Y. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00015 · Cited by 48 · see citing works
Astaxanthin Supplementation Does Not Attenuate Muscle Injury Following Eccentric Exercise in Resistance-Trained Men
Bloomer, R. J., Fry, A. C., Schilling, B. K., Chiu, L. Z. F., Hori, N., & Weiss, L. W. (2005) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.15.4.401 · Cited by 47 · see citing works
Omega-3 Fatty Acids-Enriched Fish Oil Activates AMPK/PGC-1α Signaling and Prevents Obesity-Related Skeletal Muscle Wasting
Liu, S., Chiu, C., Wang, L.-P., & Chiang, M. (2019) · Marine Drugs · doi:10.3390/md17060380 · Cited by 47 · see citing works
Astaxanthin Prevents Atrophy in Slow Muscle Fibers by Inhibiting Mitochondrial Reactive Oxygen Species via a Mitochondria-Mediated Apoptosis Pathway
Sun, L., Miyaji, N., Yang, M., Mills, E. M., Taniyama, S., Uchida, T., Nikawa, T., Li, J., Shi, J., Tachibana, K., et al. (2021) · Nutrients · doi:10.3390/nu13020379 · Cited by 45 · see citing works
Protective effects of astaxanthin on capillary regression in atrophied soleus muscle of rats
Kanazashi, M., Okumura, Y., Al‐Nassan, S., Murakami, S., Kondo, H., Nagatomo, F., Fujita, N., Ishihara, A., Roy, R. R., & Fujino, H. (2012) · Acta Physiologica · doi:10.1111/apha.12018 · Cited by 44 · see citing works
Potential therapeutic impact of omega-3 long chain-polyunsaturated fatty acids on inflammation markers in Duchenne muscular dystrophy: A double-blind, controlled randomized trial
Rodríguez‐Cruz, M., Cruz‐Guzmán, O. D. R., Almeida‐Becerril, T., Solís-Serna, A. D., Atilano-Miguel, S., Sánchez-González, J. R., Barbosa-Cortés, L., Ruíz-Cruz, E. D., Huicochea, J. C., Cárdenas‐Conejo, A., et al. (2017) · Clinical Nutrition · doi:10.1016/j.clnu.2017.09.011 · Cited by 44 · see citing works
Impact of Light Stress on the Synthesis of Both Antioxidants Polyphenols and Carotenoids, as Fast Photoprotective Response in Chlamydomonas reinhardtii: New Prospective for Biotechnological Potential of This Microalga
Faraloni, C., Lorenzo, T. D., & Bonetti, A. (2021) · Symmetry · doi:10.3390/sym13112220 · Cited by 44 · see citing works
Physical Activity and Health in Chronic Kidney Disease
Wilund, K. R., Thompson, S., Viana, J. L., & Wang, A. Y.-M. (2021) · Contributions to nephrology · doi:10.1159/000517696 · Cited by 43 · see citing works
Rutin and Gallic Acid Regulates Mitochondrial Functions via the SIRT1 Pathway in C2C12 Myotubes
Chang, W.-T., Huang, S., Cheng, H. T., Chen, S., & Hsu, C. (2021) · Antioxidants · doi:10.3390/antiox10020286 · Cited by 41 · see citing works
High-cell-density cultivation of the flagellate alga Poterioochromonas malhamensis for biomanufacturing the water-soluble β-1,3-glucan with multiple biological activities
Ma, M., Lǐ, Y., Chen, J., Wang, F., Li, Y., Li, Y., Zhang, B., Ding, Y., Han, D., Hu, J., et al. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.125447 · Cited by 41 · see citing works
Ubiquitin‐dependent and ‐independent mitochondrial protein quality controls: implications in ageing and neurodegenerative diseases
Germain, D. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06502.x · Cited by 40 · see citing works
Dietary Supplementation with the MicroalgaGaldieria sulphuraria(Rhodophyta) Reduces Prolonged Exercise-Induced Oxidative Stress in Rat Tissues
Carfagna, S., Napolitano, G., Barone, D., Pinto, G., Pollio, A., & Venditti, P. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/732090 · Cited by 40 · see citing works
Skeletal muscle mitochondria in health and disease
Mario, A. D., Gherardi, G., Rizzuto, R., & Mammucari, C. (2021) · Cell Calcium · doi:10.1016/j.ceca.2021.102357 · Cited by 40 · see citing works
Omega-3 fatty acids differentially modulate enzymatic anti-oxidant systems in skeletal muscle cells
da Silva, E. P., Nachbar, R. T., Levada‐Pires, A. C., Hirabara, S. M., & Lambertucci, R. H. (2015) · Cell Stress and Chaperones · doi:10.1007/s12192-015-0642-8 · Cited by 39 · see citing works
Protectin DX ameliorates palmitate- or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice
Jung, T. W., Kim, H., El‐Aty, A. M. A., & Jeong, J. H. (2017) · Scientific Reports · doi:10.1038/s41598-017-01603-9 · Cited by 39 · see citing works
Microalgae and Its Use in Nutraceuticals and Food Supplements
Hemantkumar, J. N., & Mor, I. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.90143 · Cited by 39 · see citing works
Microalgae as a potential therapeutic drug candidate for neurodegenerative diseases
Parameswari, R. P., & Thangavelu, L. P. (2022) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2022.09.009 · Cited by 38 · see citing works
Effect of strength training combined with antioxidant supplementation on muscular performance
Dutra, M. T., Álex, S., Mota, M. R., Sales, N. B., Brown, L. E., & Bottaro, M. (2018) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2017-0866 · Cited by 36 · see citing works
trans ‐ferulic acid attenuates hyperglycemia‐induced oxidative stress and modulates glucose metabolism by activating AMPK signaling pathway in vitro
Singh, S. S. B., & Patil, K. N. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14038 · Cited by 35 · see citing works
Dietary astaxanthin supplementation attenuates disuse-induced muscle atrophy and myonuclear apoptosis in the rat soleus muscle
Yoshihara, T., Yamamoto, Y., Shibaguchi, T., Miyaji, N., Kakigi, R., Naıto, H., Goto, K., Ohmori, D., Yoshioka, T., & Sugiura, T. (2016) · The Journal of Physiological Sciences · doi:10.1007/s12576-016-0453-4 · Cited by 34 · see citing works
The multiple facets of mitochondrial regulations controlling cellular thermogenesis
Beignon, F., Guéguen, N., Tricoire-Leignel, H., Mattei, C., & Lenaers, G. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04523-8 · Cited by 34 · see citing works
Microalgae: A Promising Future
Caroppo, C., & Pagliara, P. (2022) · Microorganisms · doi:10.3390/microorganisms10081488 · Cited by 33 · see citing works
The Effects of Spirulina Supplementation on Redox Status and Performance Following a Muscle Damaging Protocol
Pappas, A., Τσιόκανος, Α., Fatouros, I. G., Poulios, A., Kouretas, D., Goutzourelas, N., Giakas, G., & Jamurtas, A. Z. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073559 · Cited by 32 · see citing works
Improvement of green tea polyphenol with milk on skin with respect to antioxidation in healthy adults: a double-blind placebo-controlled randomized crossover clinical trial
Chiu, H., Lin, T., Shen, Y., Venkatakrishnan, K., & Wang, C. (2015) · Food & Function · doi:10.1039/c5fo01271f · Cited by 31 · see citing works
Dietary Intake of β-Glucans Can Prolong Lifespan and Exert an Antioxidant Action on Aged Fish Nothobranchius guentheri
Song, L., Zhou, Y., Ni, S., Wang, X., Yuan, J., Zhang, Y., & Zhang, S. (2019) · Rejuvenation Research · doi:10.1089/rej.2019.2223 · Cited by 31 · see citing works
First evidence of ovothiol biosynthesis in marine diatoms
Milito, A., Castellano, I., Burn, R., Seebeck, F. P., Brunet, C., & Palumbo, A. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.01.010 · Cited by 30 · see citing works
First evidence of dermo-protective activity of marine sulfur-containing histidine compounds
Brancaccio, M., Milito, A., Viegas, C., Palumbo, A., Simes, D. C., & Castellano, I. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.09.017 · Cited by 30 · see citing works
Ferulic acid promotes muscle glucose uptake and modulate dysregulated redox balance and metabolic pathways in ferric‐induced pancreatic oxidative injury
Salau, V. F., Erukainure, O. L., Koorbanally, N. A., & Islam, M. S. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.13641 · Cited by 29 · see citing works
Ergothioneine Improves Aerobic Performance Without Any Negative Effect on Early Muscle Recovery Signaling in Response to Acute Exercise
Fovet, T., Guilhot, C., Delobel, P., Chopard, A., Py, G., & Brioche, T. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.834597 · Cited by 29 · see citing works
Long-chain polyunsaturated fatty acids amend palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes
Chen, S., Chen, P., Wu, Y., Chen, C., Chen, H., Lii, C., Sun, H., & Liu, K. (2015) · Food & Function · doi:10.1039/c5fo00704f · Cited by 27 · see citing works
Total Phenolic Levels, In Vitro Antioxidant Properties, and Fatty Acid Profile of Two Microalgae, Tetraselmis marina Strain IMA043 and Naviculoid Diatom Strain IMA053, Isolated from the North Adriatic Sea
Trentin, R., Custódio, L. M. B., Rodrigues, M. J., Moschin, E., Sciuto, K., Silva, J. P. D., & Moro, I. (2022) · Marine Drugs · doi:10.3390/md20030207 · Cited by 26 · see citing works
Possible Role of Nutrition in Prevention of Sarcopenia and Falls
Schneider, D., & Trence, D. (2019) · Endocrine Practice · doi:10.4158/ep-2019-0144 · Cited by 25 · see citing works
Chlorella vulgaris Ameliorates Oxidative Stress and Improves the Muscle Regenerative Capacity of Young and Old Sprague-Dawley Rats
Azlan, N. Z., Yusof, Y. A. M., & Makpol, S. (2020) · Nutrients · doi:10.3390/nu12123752 · Cited by 25 · see citing works
Effects of Fucoxanthin on the Inhibition of Dexamethasone-Induced Skeletal Muscle Loss in Mice
Yoshikawa, M., Hosokawa, M., Miyashita, K., Nishino, H., & Hashimoto, T. (2021) · Nutrients · doi:10.3390/nu13041079 · Cited by 25 · see citing works
Bioprospecting of tropical microalgae for high-value products: n-3 polyunsaturated fatty acids and carotenoids
Katayama, T., Rahman, N. A., Khatoon, H., Kasan, N. A., Nagao, N., Yamada, Y., Takahashi, K., Furuya, K., Wahid, M. E. A., Yusoff, F. M., et al. (2022) · Aquaculture Reports · doi:10.1016/j.aqrep.2022.101406 · Cited by 25 · see citing works
Effect of microalga-based diet on oxidative stress enzymes of African catfish, Clarias gariepinus
Sharma, S., Shah, E., Davla, D., Dixit, G., Patel, A., & Kumar, A. K. (2019) · International aquatic research. · doi:10.1007/s40071-019-00245-z · Cited by 24 · see citing works
MAJOR BIOACTIVE PROPERTIES OF GANODERMA POLYSACCHARIDES: A REVIEW
Bhat, Z. A., Wani, A. H., War, J. M., & Bhat, M. Y. (2021) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2021.v14i3.40390 · Cited by 23 · see citing works
Omega-3 Polyunsaturated Fatty Acids Mitigate Palmitate-Induced Impairments in Skeletal Muscle Cell Viability and Differentiation
Tachtsis, B., Whitfield, J., Hawley, J. A., & Hoffman, N. J. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00563 · Cited by 22 · see citing works
The Role of Food Supplementation in Microcirculation—A Comprehensive Review
Raposo, A., Saraiva, A., Ramos, F., Carrascosa, C., Raheem, D., Bárbara, R., & Silva, H. (2021) · Biology · doi:10.3390/biology10070616 · Cited by 22 · see citing works
Promoting a pro-oxidant state in skeletal muscle: Potential dietary, environmental, and exercise interventions for enhancing endurance-training adaptations
Jordan, A., Perry, C. G. R., & Cheng, A. J. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.09.014 · Cited by 22 · see citing works
Eicosapentaenoic acid abolishes inhibition of insulin-induced mTOR phosphorylation by LPS via PTP1B downregulation in skeletal muscle
Wei, H., Deng, Z., Jiang, S., Song, T., Zhou, Y., Peng, J., & Tao, Y. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.10.029 · Cited by 21 · see citing works
Omega-3 fatty acids and human skeletal muscle
Ferguson, E. J., Seigel, J., & McGlory, C. (2020) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000723 · Cited by 21 · see citing works
Ferulic Acid Alleviates Oxidative Stress-Induced Cardiomyocyte Injury by the Regulation of miR-499-5p/p21 Signal Cascade
Sun, S., Ruan, Y., Yan, M., Xu, K., Yang, Y., Shen, T., & Jin, Z. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/1921457 · Cited by 21 · see citing works

Flagged first, then by citations

Sorted by citations

Algae-Derived Natural Products in Diabetes and Its Complications—Current Advances and Future Prospects
Pereira, L., & Valado, A. (2023) · Life · doi:10.3390/life13091831 · Cited by 59 · see citing works
Microalgae as a Sustainable Source of Antioxidants in Animal Nutrition, Health and Livestock Development
Mavrommatis, A., Tsiplakou, E., Zerva, A., Pantiora, P. D., Georgakis, N., Tsintzou, G. P., Madesis, P. B., & Labrou, N. E. (2023) · Antioxidants · doi:10.3390/antiox12101882 · Cited by 54 · see citing works
Microalgae Bioactives for Functional Food Innovation and Health Promotion
Guil-Guerrero, J. L., & Prates, J. A. M. (2025) · Foods · doi:10.3390/foods14122122 · Cited by 47 · see citing works
“Finally, novel evidence suggests that microalgae may protect mitochondrial function and muscle tissue from oxidative damage, offering benefits for ageing populations and individuals with metabolic or muscular disorders [47].”
Antioxidants from microalgae and their potential impact on human well-being
Pereira, L., Cotas, J., & Valado, A. (2024) · Exploration of Drug Science · doi:10.37349/eds.2024.00048 · Cited by 48 · see citing works
An integrated approach of algae-bacteria mediated treatment of industries generated wastewater: Optimal recycling of water and safe way of resource recovery
Dhanker, R., Khatana, K., Verma, K., Singh, A., Heena, Kumar, R., & Mohamed, H. I. (2023) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2023.102936 · Cited by 48 · see citing works
Performance, mechanism regulation and resource recycling of bacteria-algae symbiosis system for wastewater treatment: A review
Liu, S., Kong, Z., Guo, H., Zhang, Y., Han, X., Gao, Y., Daigger, G. T., Zhang, G., Li, R., Liu, Y., et al. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.125019 · Cited by 39 · see citing works
A Review of the Sustainability, Chemical Composition, Bioactive Compounds, Antioxidant and Antidiabetic Activity, Neuroprotective Properties, and Health Benefits of Microalgae
Dimopoulou, M., Kolonas, A., Stagos, D., & Gortzi, O. (2025) · Biomass · doi:10.3390/biomass5010011 · Cited by 34 · see citing works
Advances in research on cell models for skeletal muscle atrophy
Li, L., Huang, C., Pang, J., Huang, Y., Chen, X., & Chen, G. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115517 · Cited by 34 · see citing works
Anticancer Properties of Macroalgae: A Comprehensive Review
Frazzini, S., & Rossi, L. (2025) · Marine Drugs · doi:10.3390/md23020070 · Cited by 32 · see citing works
Microalgae supplementation improves goat milk composition and fatty acid profile: a meta-analysis and meta-regression
Boukrouh, S., Mnaouer, I., de Souza, P. M., Hornick, J., Nilahyane, A., Amiri, B. E., & Hirich, A. (2025) · Archives animal breeding/Archiv für Tierzucht · doi:10.5194/aab-68-223-2025 · Cited by 33 · see citing works
Exploring the Relationship Between Gut Microbiota and Sarcopenia Based on Gut–Muscle Axis
Li, W., Sheng, R., Cao, M., & Rui, Y. (2024) · Food Science & Nutrition · doi:10.1002/fsn3.4550 · Cited by 22 · see citing works
Effect of cheese whey on phycobiliproteins production and FAME profile by Arthrospira platensis (Spirulina): Promoting the concept of a circular bio-economy
Cavallini, A., Torre, S., Usai, L., Casula, M., Fais, G., Nieri, P., Concas, A., & Lutzu, G. A. (2024) · Sustainable Chemistry and Pharmacy · doi:10.1016/j.scp.2024.101625 · Cited by 18 · see citing works
Algal and Fungal Antioxidants Alleviate Oxidative Stress‐Induced Reproductive Defects
Arslan, N. P., Albayrak, S., Savaş, A., Hacımüftüoğlu, A., Orak, T., Ozdemir, A., Karadagoglu, O., Yildirim, S., Yılmaz, H. Ç., & Taşkın, M. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70301 · Cited by 17 · see citing works
Microalgae-derived antioxidants and antimicrobials: a sustainable approach for natural food preservatives
Singh, L. A., Kumari, P., Kumar, P., Yadav, A., Bhardwaj, R., Swapnil, P., & Meena, M. (2025) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2025.1669731 · Cited by 19 · see citing works
Combined Nutrition with Exercise: Fueling the Fight Against Sarcopenia Through a Bibliometric Analysis and Review
Zeng, Y., He, X., Peng, X., Zhao, L., Yin, C., & Mao, S. (2024) · International Journal of General Medicine · doi:10.2147/ijgm.s462594 · Cited by 14 · see citing works
Characterization of Microalgae Biomass-Based Composites Obtained through Rotational Molding
Díaz, S., Romero, F., Suárez, L., Ríos, R., Alemán, M., Venuleo, M., & Ortega, Z. (2024) · Polymers · doi:10.3390/polym16131807 · Cited by 14 · see citing works
Harnessing the power of marine terpenoids against diabetes-associated oxidative stress
Rampengan, D. D. C. H., Lele, J. A. J. M. N., Romano, R., Taslim, N. A., Tjandrawinata, R. R., Santini, A., & Nurkolis, F. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1651804 · Cited by 12 · see citing works
Nutritional and Antioxidative Benefits of Dietary Macroalgae Supplementation in Weaned Piglets
Czech, A., Woś, K., Muszyński, S., & Tomaszewska, E. (2024) · Animals · doi:10.3390/ani14040549 · Cited by 12 · see citing works
A Biorefinery Approach Integrating Lipid and EPS Augmentation Along with Cr (III) Mitigation by Chlorella minutissima
Choudhary, S., Tiwari, M., & Poluri, K. M. (2024) · Cells · doi:10.3390/cells13242047 · Cited by 11 · see citing works
Algae as a sustainable feed resource: revolutionizing animal nutrition
Kazemi, M. (2025) · Aquaculture International · doi:10.1007/s10499-025-02195-2 · Cited by 12 · see citing works
The Effects of Omega-3 Supplementation Combined with Strength Training on Neuro-Biomarkers, Inflammatory and Antioxidant Responses, and the Lipid Profile in Physically Healthy Adults
Okut, S., Ozan, M., Buzdağlı, Y., Uçar, H., İnaç, M. R., Han, M. T., Bayram, E., & Baygutalp, N. K. (2025) · Nutrients · doi:10.3390/nu17132088 · Cited by 9 · see citing works
Inhibition of free radicals and inflammation on RAW264.7 macrophage cell line by Arthrospira platensis extract
Srisai, P., Suriyaprom, S., Khacha-ananda, S., Panya, A., Bäumler, H., & Tragoolpua, Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-27372-4 · Cited by 9 · see citing works
Application of Microbial Consortium to the Pilot-Scale Treatment of Primary Treated Sewage Wastewater
Singh, B., Sharma, N., Sharma, S. G., Dhir, A., Kocher, G. S., & Mamane, H. (2024) · Water Air & Soil Pollution · doi:10.1007/s11270-024-06953-5 · Cited by 8 · see citing works
Ultrasound-assisted extraction enhances recovery of antioxidant-rich carbohydrate fraction from mixed microalgae species
Ooi, E. Z. H., Chan, E., Song, C. P., Pushpamalar, J., & Lee, Y. (2025) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2025.107656 · Cited by 8 · see citing works
Microalgae biomass as a sustainable solution for food security: Advances in biotechnology and their role in achieving Sustainable Development Goals
Iñíguez-Moreno, M., González-Meza, G. M., Araújo, R. G., Flores-Contreras, E. A., & de la Rosa, O. (2025) · Bioresource Technology Reports · doi:10.1016/j.biteb.2025.102183 · Cited by 8 · see citing works
Chemical-functional characterization of Ascophyllum nodosum and Phymatolithon calcareum and dietary supplementation in post-weaning pigs
Frazzini, S., Reggi, S., Dell’Anno, M., Fifi, A. P., Scaglia, E., Ferri, I., & Rossi, L. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1431091 · Cited by 6 · see citing works
Combined Effects of Spirulina Liquid Extract and Endurance Training on Aerobic Performance and Muscle Metabolism Adaptation in Wistar Rats
Vignaud, J., Loiseau, C., Côme, M., Martin, I., Rasoanarivo, R., Hérault, J., Mayer, C., Lépine, O., & Ulmann, L. (2025) · Nutrients · doi:10.3390/nu17020283 · Cited by 6 · see citing works
Self-citation
Alternative protein sources and healthy skeletal muscle aging: A narrative review
Dai, Z., Zhao, Y., Ke, Y., Huang, J., Zhu, J., Wu, H., Yang, Y., Shang, H., & Xia, Z. (2025) · Journal of Functional Foods · doi:10.1016/j.jff.2025.106990 · Cited by 6 · see citing works
A Green Revolution in Antioxidant Research: Harnessing Microalgae for Wellness and LongevityPreprint
Pereira, L., Cotas, J., & Valado, A. (2023) · Preprints.org · doi:10.20944/preprints202309.0509.v1 · Cited by 4 · see citing works
A microalgae Picochlorum sp. AZL19 from Moroccan Mediterranean as a novel source of antioxidant compounds
Ouzakar, S., Senhaji, N. S., Abriouel, H., Manetsberger, J., Caballero‐Casero, N., Rubio, S., & Abrini, J. (2025) · Algal Research · doi:10.1016/j.algal.2025.103960 · Cited by 4 · see citing works
Microalgae as biofactories of natural antioxidants: from stress responses to industrial applications
Rahman, N. A., KATAYAMA, T., Wahid, M. E. A., Jusoh, M., Yusoff, F. M., & Takahashi, K. (2026) · Journal of Applied Phycology · doi:10.1007/s10811-026-03804-0 · Cited by 4 · see citing works
Microalgae and exercise: from molecular mechanisms and brain health to clinical perspectives in the context of 3P medicine
Bo, X. (2025) · The EPMA Journal · doi:10.1007/s13167-025-00405-8 · Cited by 4 · see citing works
Bioactivity of autotrophic and mixotrophic Tetraselmis chuii (CCAP 66/21B) extracts against H2O2-mediated stress in A549 cells.
Conlon, T., Herbert, H., Campion, E. M., & Touzet, N. (2025) · Process Biochemistry · doi:10.1016/j.procbio.2025.05.007 · Cited by 5 · see citing works
Microalgae in multipollutant synergistic removal: mechanisms, regulatory networks, and cross-scale integration
Song, C., Shi, Z., & Li, L. (2026) · RENDICONTI LINCEI · doi:10.1007/s12210-025-01404-7 · Cited by 3 · see citing works
Evaluation of dietary supplementation of Ascophyllum nodosum and Lithothamnium calcareum as functional algae in F4+ Escherichia coli challenged piglets
Dell’Anno, M., Frazzini, S., Reggi, S., Ferri, I., Scaglia, E., Schiasselloni, L., Inglesi, A., Riva, F., Verdile, N., Pasquariello, R., et al. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1430347 · Cited by 3 · see citing works
Mitochondrial Dysfunction and Oxidative Stress: Emerging Insights in Muscle and Cardiovascular Disease Mechanisms
Riou, M., & Gény, B. (2025) · Antioxidants · doi:10.3390/antiox14080902 · Cited by 3 · see citing works
The Potential of Algae in Treating Celiac Disease
Asri, N., Rostami‐Nejad, M., Azodi, M. Z., Rezaei, M. S., & ROBATI, R. M. (2024) · International Journal of Medical Toxicology and Forensic Medicine · doi:10.32598/ijmtfm.v13i4.43127 · Cited by 2 · see citing works
Algae Production Technologies
Russell, C., Krishnamoorthy, A., & Rodríguez, C. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15738-7.00075-1 · Cited by 2 · see citing works
Cold Plasma Technology for Sustainable Food Waste Decontamination
Das, S., Gon, A., Chatterjee, A., & Appukutty, M. (2025) · Methods and protocols in food science · doi:10.1007/978-1-0716-4646-5_8 · Cited by 1 · see citing works
Microalgae for the prevention of cardiovascular diseases
do Nascimento, T. C., Pinheiro, P. N., Nörnberg, M. L., Fagundes, M. B., Baseggio, A. M., & Maróstica, M. R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-22080-7.00041-7 · Cited by 2 · see citing works
Spirulina liquid extract regulates gene expression related to glucose and lipid metabolisms of soleus muscle during exercise training in young male Wistar rats fed a high-fat diet
Vignaud, J., Loiseau, C., Côme, M., Hérault, J., Mayer, C., Lépine, O., & Ulmann, L. (2025) · Nutrition Research · doi:10.1016/j.nutres.2025.09.006 · Cited by 2 · see citing works
Self-citation
Modulating cecal microbiota and systemic physiology in broilers through non-antibiotic dietary approaches
Alhujaili, W. F., Hafiz, H. A., Alshehry, G. A., Aldhalmi, A. K., Khan, M. M. H., Kamal, M., & El‐Mekkawy, M. M. (2025) · The Journal of Applied Poultry Research · doi:10.1016/j.japr.2025.100635 · Cited by 1 · see citing works
Research trends and hotspots of microalgae protein as a functional ingredient in plant-based foods: A bibliometric analysis based on the web of science
He, J., Xu, H., Lu, K., Guo, C., Du, M., & Jia, R. (2026) · Algal Research · doi:10.1016/j.algal.2026.104541 · Cited by 1 · see citing works
Iron biofortification as a promising strategy to improve productivity and nutritional value of Arthrospira platensis (spirulina)
Gholizadeh, F., & Zarinkamar, F. (2026) · Scientific Reports · doi:10.1038/s41598-026-40520-8 · Cited by 1 · see citing works
Effect of Media Formulations on Chlorophyll, Antioxidant Activity of Chlorella vulgaris and Its Potential as a Health Supplement
Iriani, D., Feliatra, Hasan, B., Karnila, R., Chaiyanate, N., & Rozi (2024) · Jurnal Ilmiah Perikanan dan Kelautan · doi:10.20473/jipk.vi.61083 · Cited by 1 · see citing works
Marine secondary metabolites in oxidative stress are promising
Mapa, M. S. T., & Kadigamuwa, C. C. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-29843-1.00004-5 · Cited by 1 · see citing works
Antioxidant System Interventions for Enhancing Spinal Health in Astronaut and Terrestrial Workers
(2023) · doi:10.47461/isoes.2023.bittner
Efficacy and mechanisms of antiretroviral drugs removal by algaefrom wastewater treatment plants
Reddy, K. (2024) · doi:10.51415/10321/5444
Optimization of Effervescent Tablets in Sensory Acceptance from the Active Ingredients of Fish Protein Hydrolysate and Microalgae Chlorellae sp. powder
Yuniarti, T., Putri, N. A., Dharmayanti, N., Mulyono, M., Sugiwati, S., Martosuyono, P., Dewi, I. J. P., Maulani, A., & Hidayat, T. (2024) · Jurnal Ilmiah Perikanan dan Kelautan · doi:10.20473/jipk.vi.56019
Bioprospecting of Microalgae: Unveiling Their Promise in Food and Therapeutic Applications
Nagda, T., & Patil, R. (2025) · Environmental science and engineering · doi:10.1007/978-3-031-62660-9_25
Nutritional and functional microalgae for human health
Afzaal, M., Imran, A., Iqbal, S. S., Akhtar, A. B. T., Rasheed, R., Farhan, M., Nawaz, R., & Mansoor, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-24006-5.00010-9
Preliminary Biological Assessments of Some Algae Basis Biomaterials
Marian, T., Radu, N., Voicescu, M., Nistor, C. L., Pirvu, L. C., Mihaila, M. A., & Bostan, M. (2025) · Journal of Marine Science and Engineering · doi:10.3390/jmse13020318
Haematological Consequences of Food Contaminants
Das, S., Goswami, R., Chatterjee, A., & Appukutty, M. (2025) · Springer eBooks · doi:10.1007/978-3-031-94582-3_14
Evidence of use of microalgae on glycemic control and glucose metabolism
Pereira, L. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-22080-7.00035-1
Microalgae in Medicine: Emerging Therapeutic Applications
Nasri, N., & Chavoshy, H. Z. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1012660
Small Molecules from Microalgae as an Emerging Sustainable Alternative for Disease Management
Treviño-Almaguer, D., Espinosa-Rodríguez, B. A., Balderas-Renterı́a, I., & Llerena, J. L. G. (2025) · Springer eBooks · doi:10.1007/978-3-032-03675-9_7
Microalgae: the nutritional green gold
Das, S., Irani, R., Chatterjee, A., & Abdullahi, A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-32920-3.00023-9
Antioxidant Potentials of Algae and Effects Against Liver and Related Diseases
Balogun, F. O., & Sabiu, S. (2026) · Reference series in phytochemistry · doi:10.1007/978-3-031-80866-1_20-1
A state-of-the-art in exploring microalgal vitamins: Advancements in production, extraction, market potential, applications, and perspectives for a sustainable future
Maity, S., & Yadav, A. K. (2026) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2026.2625200
Exploring the bioactive properties of Tetraselmis sp. against the emerging contaminant BDE-47
Louati, C., Manuguerra, S., Zili, F., Bessadok, B., Renda, G., Santulli, A., Messina, C. M., & Sadok, S. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.108431
Microalgal biomass as a functional dietary ingredient for growth and performance enhancement in Oreochromis sp. alevinsPreprint
Llanes, A., & Herrera, N. A. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6250979
Effects of dietary liquid Spirulina platensis on growth performance and oxidative status of common carp
Barbacariu, C.-A., Plavan, G. I., Nicoară, M.-N., Burducea, M., Dîrvariu, L., Șerban, D. A., Todirașcu-Ciornea, E., Dumitru, G., Costică, N., Dobrojan, G., et al. (2026) · Frontiers in Animal Science · doi:10.3389/fanim.2026.1786338
Integrated physiological and transcriptomic evidence for enhanced phenanthrene toxicity under microplastics co-exposure in the marine microalga Isochrysis galbana
Zheng, G., Tao, Y., Ma, X., Zhou, S., & Xie, Z. (2026) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2026.142124
Dietary Spirulina platensis phycocyanin enhances growth performance, antioxidant status, and immune-related gene expression in Japanese quails (Coturnix japonica)
Hendam, B. M., Morsy, M. H. E., Aljàrari, R. M., Alowaidi, S. A., Eissa, M. E. H., Eissa, E. H., & El‐Aziz, Y. M. A. (2026) · Scientific Reports · doi:10.1038/s41598-026-45365-9
Pharmacological Insights into Antioxidants for Oxidative Stress Management
Ghume, P., Khatri, D., & Kushwaha, S. (2026) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-032-19837-2_15
Bio-stimulants enhance cold tolerance in tobacco through antioxidant defense and photosynthetic regulation
Dev, W., Yang, K., Ma, S., Zhang, J., Zou, P., Li, Y., Xie, S., Jing, C., LIU, Y. F., & Hu, Z. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1884028
Immunogenicity and Growth Response of Atlantic Salmon to Dietary Inclusion of Marine Diatom, Skeletonema marinoi, Under Vibrio anguillarum Serotype O3 Challenge
Meesala, K.-M., Adeyemi, A., Janson, S., Hong, J., Polinski, M. P., Burr, G., Lomas, M. W., Sealey, W. M., Bouchard, D. A., & Habte‐Tsion, H. (2026) · Aquaculture Journal · doi:10.3390/aquacj6030030
Hormophysa cuneiformis protects against methamphetamine-induced hepatotoxicity via antioxidant, anti-inflammatory, and autophagy-regulatory mechanisms: histological and biochemical studies
Elhusseiny, M. E., El-Kelany, R. S., El‐Shenody, R. A., El-Hashash, M. S., Elshobary, M. E., & Alkafaas, S. S. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1913493
Antioxidant Interventions on Muscle Function and Mass in Aging-Related Muscle Decline: A Systematic Review of Preclinical and Clinical Evidence
Li, X., Zhou, K., Wong, R. M. Y., Cheung, W., & Cui, C. (2026) · Antioxidants · doi:10.3390/antiox15091167
Effects of anti-aging diets and exercise on age-related musculoskeletal diseases via gut microbiota modulation
Yu, M., Guo, P., Liu, Q., & Zhang, X. (2026) · Annals of Medicine · doi:10.1080/07853890.2026.2726635
A solvent-free route to high-value UV filters: sustainable production of mycosporine-like amino acids from Klebsormidium flaccidum ASYA18
Görünmek, M., & Çakmak, T. (2026) · Sustainable Chemistry and Pharmacy · doi:10.1016/j.scp.2026.102591
Nutritional support and biologically active components in comprehensive rehabilitation of patients after ischemic stroke
Сергеевна, З. Т., Борисовна, Ф. Т., & Zainudinov, Z. M. (2026) · Medical alphabet · doi:10.33667/2078-5631-2026-16-40-44

Authors: Vignaud, J., Loiseau, C., Hérault, J., Mayer, C., Côme, M., Martin, I., & Ulmann, L.
Affiliations: Le Mans Université (FR)
BiOSSE (Biology of Organisms, Stress, Health, Environment), Institut Universitaire de Technologie, Département Génie Biologique, Le Mans Université, F-53020 Laval, France
Corresponding author: Ulmann, Lionel
ORCID: Vignaud, Jordi
Loiseau, Céline
Mayer, Claire
Ulmann, Lionel
Venue: Antioxidants
Publisher: MDPI AG
Published: 2023-05-05
Volume: 12
Issue: 5
Pages: 1050
ISSN: 2076-3921 (ISSN-L)
DOI: 10.3390/antiox12051050
PMC: PMC10215861
OpenAlex: W4372347288
Cited by: 72
References: 213
Citations by year: 2026: 19 · 2025: 31 · 2024: 16 · 2023: 6
FWCI: 2.44
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Antioxidants (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
HAL (submittedVersion, other-oa)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Collectivités Locales Mayennaises
Topics: Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Keywords: microalgae, antioxidants, mitochondrial function, reactive oxygen species, sarcopenia, chronic obstructive pulmonary disease, Duchenne muscular dystrophy, exercise-induced muscle damage, muscle atrophy, antioxidant pathways, protein synthesis, carotenoids

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Microalgae Produce Antioxidant Molecules with Potential Preventive Effects on Mitochondrial Functions and Skeletal Muscular Oxidative Stress

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks