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Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review
Open accessAbstract
Astaxanthin, a xanthophyll carotenoid, is a secondary metabolite naturally synthesized by a number of bacteria, microalgae, and yeasts. The commercial production of this pigment has traditionally been performed by chemical synthesis, but the microalga Haematococcus pluvialis appears to be the most promising source for its industrial biological production. Due to its collective diverse functions in skin biology, there is mounting evidence that astaxanthin possesses various health benefits and important nutraceutical applications in the field of dermatology. Although still debated, a range of potential mechanisms through which astaxanthin might exert its benefits on skin homeostasis have been proposed, including photoprotective, antioxidant, and anti-inflammatory effects. This review summarizes the available data on the functional role of astaxanthin in skin physiology, outlines potential mechanisms involved in the response to astaxanthin, and highlights the potential clinical implications associated with its consumption.
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In the citing paper
“Oral administration of astaxanthin is protective against UV-induced skin deterioration and is helpful to maintain healthy skin.”
From Boosting the Photoaged Skin: The Potential Role of Dietary Components (2021) · cites this paper as [96]
In the citing paper
“Carotenoids prevent ageing, stimulate fibroblasts to produce collagen and elastin, inhibit the activity of MMPs, and exhibit anti-inflammatory and UV-filtering effects [222,226,231].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“Carotenoids prevent ageing, stimulate fibroblasts to produce collagen and elastin, inhibit the activity of MMPs, and exhibit anti-inflammatory and UV-filtering effects [222,226,231].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“Carotenoids prevent ageing, stimulate fibroblasts to produce collagen and elastin, inhibit the activity of MMPs, and exhibit anti-inflammatory and UV-filtering effects [222,226,231].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“Carotenoids prevent ageing, stimulate fibroblasts to produce collagen and elastin, inhibit the activity of MMPs, and exhibit anti-inflammatory and UV-filtering effects [222,226,231].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“They have been shown to improve the elasticity, hydration and texture of skin; reduce TEWL; lighten the skin; reduce discoloration; and delay the signs of photoaging [222,231,232,233].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“Carotenoids prevent ageing, stimulate fibroblasts to produce collagen and elastin, inhibit the activity of MMPs, and exhibit anti-inflammatory and UV-filtering effects [222,226,231].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“They have been shown to improve the elasticity, hydration and texture of skin; reduce TEWL; lighten the skin; reduce discoloration; and delay the signs of photoaging [222,231,232,233].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“They have been shown to improve the elasticity, hydration and texture of skin; reduce TEWL; lighten the skin; reduce discoloration; and delay the signs of photoaging [222,231,232,233].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“They have been shown to improve the elasticity, hydration and texture of skin; reduce TEWL; lighten the skin; reduce discoloration; and delay the signs of photoaging [222,231,232,233].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“They have been shown to improve the elasticity, hydration and texture of skin; reduce TEWL; lighten the skin; reduce discoloration; and delay the signs of photoaging [222,231,232,233].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“They have been shown to improve the elasticity, hydration and texture of skin; reduce TEWL; lighten the skin; reduce discoloration; and delay the signs of photoaging [222,231,232,233].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
In the citing paper
“They have been shown to improve the elasticity, hydration and texture of skin; reduce TEWL; lighten the skin; reduce discoloration; and delay the signs of photoaging [222,231,232,233].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [222]
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Citations
Cites
Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008) · Nature · doi:10.1038/nature07205 · Cited by 11,399
The extracellular matrix: A dynamic niche in cancer progression
Lu, P., Weaver, V. M., & Werb, Z. (2012) · Journal of Cell Biology · doi:10.1083/jcb.201102147 · Cited by 3,024
Potential Role of Carotenoids as Antioxidants in Human Health and Disease
Fiedor, J., & Burda, K. (2014) · Nutrients · doi:10.3390/nu6020466 · Cited by 1,420
Astaxanthin: a review of its chemistry and applications
Higuera-Ciapara, I., Félix-Valenzuela, L., & Goycoolea, F. M. (2006) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408690590957188 · Cited by 1,287
Oxidation events and skin aging
Kammeyer, A., & Luiten, R. M. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.01.001 · Cited by 980
Shah, M. M. R., Liang, Y., Cheng, J. J., & Daroch, M. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00531 · Cited by 940
Absorption, metabolism, and transport of carotenoids
Parker, R. S. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.5.8621054 · Cited by 747
Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae
Yuan, J., Peng, J., Yin, K., & Wang, J. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000414 · Cited by 649
Carotenogenesis in the green alga Haematococcus pluvialis : Cellular physiology and stress response
Boussiba, S. (2000) · Physiologia Plantarum · doi:10.1034/j.1399-3054.2000.108002111.x · Cited by 591
Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans
Park, J. S., Chyun, J. H., Kim, Y. K., Line, L. L., & Chew, B. P. (2010) · Nutrition & Metabolism · doi:10.1186/1743-7075-7-18 · Cited by 569
Astaxanthin as feed supplement in aquatic animals
Lim, K. C., Yusoff, F. M., Shariff, M., & Kamarudin, M. S. (2017) · Reviews in Aquaculture · doi:10.1111/raq.12200 · Cited by 461
Intestinal absorption and tissue distribution of carotenoids
Furr, H. C., & Clark, R. M. (1997) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(97)00060-0 · Cited by 364
Clinical aspects and molecular diagnostics of skin aging
Zouboulis, C. C., & Makrantonaki, E. (2011) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2010.07.001 · Cited by 341
Immune suppression and skin cancer development: regulation by NKT cells
Moodycliffe, A. M., Nghiem, D. X., Clydesdale, G. J., & Ullrich, S. E. (2000) · Nature Immunology · doi:10.1038/82782 · Cited by 318
Akt: A Double-Edged Sword in Cell Proliferation and Genome Stability
Xu, N., Lao, Y., Zhang, Y., & Gillespie, D. A. (2012) · Journal of Oncology · doi:10.1155/2012/951724 · Cited by 307
Brain-Skin Connection: Stress, Inflammation and Skin Aging
Chen, Y., & Lyga, J. W. (2014) · Inflammation & Allergy - Drug Targets · doi:10.2174/1871528113666140522104422 · Cited by 280
Lee, S., Bai, S.-K., Lee, K.-S., Namkoong, S., Na, H. J., Ha, K., Han, J. A., Yim, S. V., Chang, K., Kwon, Y. G., et al. (2003) · PubMed · Cited by 279
Studies on oxidants and antioxidants with a brief glance at their relevance to the immune system
Aslani, B. A., & Ghobadi, S. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.01.014 · Cited by 276
Rao, A. R., Sindhuja, H. N., Dharmesh, S. M., Sankar, K. U., Sarada, R., & Ravishankar, G. A. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf304609j · Cited by 273
Odeberg, J. M., Lignell, Å., Pettersson, A. F., & Höglund, P. (2003) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(03)00135-0 · Cited by 267
Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential.
Kidd, P. M. (2011) · PubMed · Cited by 264
Cosmetic benefits of astaxanthin on humans subjects.
Tominaga, K., Hongo, N., Karato, M., & Yamashita, E. (2012) · Acta Biochimica Polonica · doi:10.18388/abp.2012_2168 · Cited by 248
Lee, S., Bai, S.-K., Lee, K., Namkoong, S., Na, H.-J., Ha, K., Han, J., Yim, S., Chang, K., Kwon, Y., et al. (2003) · Molecules and Cells · doi:10.1016/s1016-8478(23)13772-1 · Cited by 247
Antitumor Activity of Astaxanthin and Its Mode of Action
Jyonouchi, H., Sun, S., Iijima, K., & Gross, M. D. (2000) · Nutrition and Cancer · doi:10.1207/s15327914nc3601_9 · Cited by 226
Age-associated skin conditions and diseases: Current perspectives and future options
Blume-Peytavi, U., Kottner, J., Sterry, W., Hodin, M. W., Griffiths, T. W., Watson, R. E. B., Hay, R. J., & Griffiths, C. E. M. (2016) · The Gerontologist · doi:10.1093/geront/gnw003 · Cited by 221
Visioli, F., & Artaria, C. (2016) · Food & Function · doi:10.1039/c6fo01721e · Cited by 206
Intrinsic skin aging: the role of oxidative stress.
Poljšak, B., Dahmane, R. G., & Godić, A. (2012) · PubMed · Cited by 195
Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress
Wolf, A. M., Asoh, S., Hiranuma, H., Ohsawa, I., Iio, K., Satou, A., Ishikura, M., & Ohta, S. (2009) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2009.01.011 · Cited by 191
Antioxidants as Antidepressants
Scapagnini, G., Davinelli, S., Drago, F., LORENZO, A. D., & Oriani, G. (2012) · CNS Drugs · doi:10.2165/11633190-000000000-00000 · Cited by 188
Self-citationJyonouchi, H., Zhang, L., Gross, M., & Tomita, Y. (1994) · Nutrition and Cancer · doi:10.1080/01635589409514303 · Cited by 183
Camera, E., Mastrofrancesco, A., Fabbri, C., Daubrawa, F., Picardo, M., Sies, H., & Stahl, W. (2008) · Experimental Dermatology · doi:10.1111/j.1600-0625.2008.00790.x · Cited by 172
Safety of an Astaxanthin-Rich Haematococcus pluvialis Algal Extract: A Randomized Clinical Trial
Spiller, G. A., & Dewell, A. (2003) · Journal of Medicinal Food · doi:10.1089/109662003765184741 · Cited by 171
Tripathi, D. N., & Jena, G. (2009) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2009.12.014 · Cited by 171
[8] Catabolism and turnover of collagens: Collagenases
Birkedal‐Hansen, H. (1987) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(87)44177-3 · Cited by 157
Saw, C. L. L., Yang, Y., Guo, Y., & Kong, A. T. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.10.023 · Cited by 155
Oxidative stress in severe acute illness
Bar‐Or, D., Bar-Or, R., Rael, L. T., & Brody, E. N. (2015) · Redox Biology · doi:10.1016/j.redox.2015.01.006 · Cited by 155
Suganuma, K., Nakajima, H., Ohtsuki, M., & Imokawa, G. (2010) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2010.02.009 · Cited by 154
Davinelli, S., Bertoglio, J. C., Zarrelli, A., Pina, R., & Scapagnini, G. (2015) · Journal of the American College of Nutrition · doi:10.1080/07315724.2015.1080108 · Cited by 145
Self-citationTripathi, D. N., & Jena, G. (2009) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2009.03.017 · Cited by 145
Astaxanthin inhibits cytotoxic and genotoxic effects of cyclophosphamide in mice germ cells
Tripathi, D. N., & Jena, G. (2008) · Toxicology · doi:10.1016/j.tox.2008.03.015 · Cited by 145
Active ingredients against human epidermal aging
Lorencini, M., Brohem, C. A., Dieamant, G., Zanchin, N. I. T., & Maïbach, H. I. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.03.002 · Cited by 145
Who's on first in the cellular response to DNA damage?
Cline, S. D., & Hanawalt, P. C. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1101 · Cited by 129
Davinelli, S., Scapagnini, G., Marzatico, F., Nobile, V., Ferrara, N., & Corbi, G. (2016) · Maturitas · doi:10.1016/j.maturitas.2016.11.016 · Cited by 124
Self-citationInfluence of astaxanthin, zeaxanthin and lutein on DNA damage and repair in UVA-irradiated cells
Santocono, M., Zurria, M., Berrettini, M., Fedeli, D., & Falcioni, G. (2006) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2006.07.009 · Cited by 122
Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges
Davinelli, S., Maes, M., Corbi, G., Zarrelli, A., Willcox, D. C., & Scapagnini, G. (2016) · Immunity & Ageing · doi:10.1186/s12979-016-0070-3 · Cited by 122
Self-citationFang, Q., Guo, S., Zhou, H., Han, R., Wu, P., & Han, C. (2017) · Scientific Reports · doi:10.1038/srep41440 · Cited by 121
Protective effects of astaxanthin on skin deterioration
Tominaga, K., Hongo, N., Fujishita, M., Takahashi, Y., & Adachi, Y. (2017) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.17-35 · Cited by 115
Kishimoto, Y., Tani, M., Uto‐Kondo, H., Iizuka, M., Saita, E., Sone, H., Kurata, H., & Kondo, K. (2009) · European Journal of Nutrition · doi:10.1007/s00394-009-0056-4 · Cited by 113
Xue, X.-L., Han, X., Li, Y., Chu, X., Miao, W., Zhang, J., & Fan, S. (2017) · Stem Cell Research & Therapy · doi:10.1186/s13287-016-0464-3 · Cited by 110
Preventive effect of dietary astaxanthin on UVA-induced skin photoaging in hairless mice
Komatsu, T., Sasaki, S., Manabe, Y., Hirata, T., & Sugawara, T. (2017) · PLOS ONE · doi:10.1371/journal.pone.0171178 · Cited by 109
Possible immunomodulating activities of carotenoids in in vitro cell culture experiments.
Okai, Y., & Higashi‐Okai, K. (1996) · International Journal of Immunopharmacology · doi:10.1016/s0192-0561(97)85558-0 · Cited by 107
Cocoa Bioactive Compounds: Significance and Potential for the Maintenance of Skin Health
Scapagnini, G., Davinelli, S., Renzo, L. D., LORENZO, A. D., Olarte, H. H., Micali, G., Cicero, A. F. G., & González, S. (2014) · Nutrients · doi:10.3390/nu6083202 · Cited by 107
Self-citationAstaxanthin, a xanthophyll carotenoid, inhibits ultraviolet‐induced apoptosis in keratinocytes
Yoshihisa, Y., Rehman, M. U., & Shimizu, T. (2014) · Experimental Dermatology · doi:10.1111/exd.12347 · Cited by 105
DNA Damage, Apoptosis and Langerhans Cells—Activators of UV‐induced Immune Tolerance†
Timares, L., Katiyar, S. K., & Elmets, C. A. (2008) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2007.00284.x · Cited by 105
Effect of astaxanthin on cutaneous wound healing
Meephansan, J., Rungjang, A., Yingmema, W., Deenonpoe, R., & Ponnikorn, S. (2017) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s142795 · Cited by 105
Ultraviolet radiation-induced immunosuppression and its relevance for skin carcinogenesis
Hart, P. H., & Norval, M. (2017) · Photochemical & Photobiological Sciences · doi:10.1039/c7pp00312a · Cited by 104
Niu, T., Xuan, R., Jiang, L., Wu, W., Zhen, Z., Song, Y.-L., Hong, L., Zheng, K., Zhang, J., Xu, Q., et al. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.7b05493 · Cited by 104
The Immunologic Revolution: Photoimmunology
Ullrich, S. E., & Byrne, S. N. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.405 · Cited by 103
Chalyk, N. E., Klochkov, V. A., Bandaletova, T. Y., Kyle, N. H., & Petyaev, I. M. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.10.006 · Cited by 103
Dietary astaxanthin enhances immune response in dogs
Chew, B. P., Mathison, B. D., Hayek, M. G., Massimino, S., Reinhart, G. A., & Park, J. S. (2010) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2010.12.004 · Cited by 99
OKADA, Y., ISHIKURA, M., & MAOKA, T. (2009) · Bioscience, Biotechnology, and Biochemistry · doi:10.1271/bbb.90078 · Cited by 94 · cited 1×
“The absorption of ASX is affected by diet and by smoking, and in particular, concomitant food intake appears to increase the absorption and smoking appears to reduce the half-life of ASX [86].”
BackgroundYoon, H.-S., Cho, H. H., Cho, S., Lee, S.-R., Shin, M.-H., & Chung, J. H. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2013.3060 · Cited by 93
A new view concerning the effects of collagen hydrolysate intake on skin properties
Zague, V. (2008) · Archives of Dermatological Research · doi:10.1007/s00403-008-0888-4 · Cited by 93
Jyonouchi, H., Sun, S., Tomita, Y., & Gross, M. D. (1995) · Journal of Nutrition · doi:10.1093/jn/125.10.2483 · Cited by 90
Anti‐inflammatory effect of astaxanthin in phthalic anhydride‐induced atopic dermatitis animal model
Park, J. H., Yeo, I. J., Han, J. H., Suh, J. W., Lee, H. P., & Hong, J. T. (2017) · Experimental Dermatology · doi:10.1111/exd.13437 · Cited by 89
Kupčinskas, L., Lafolie, P., Lignell, Å., Kiudelis, G., Jonaitis, L. V., Adamonis, K., Andersen, L. P., & Wadström, T. (2008) · Phytomedicine · doi:10.1016/j.phymed.2008.04.004 · Cited by 87
Nutrition and enhancing youthful-appearing skin
Draelos, Z. D. (2010) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2010.03.019 · Cited by 86
Lin, K., Lin, K., Lu, W., Thomas, P. A., Jayakumar, T., & Sheu, J. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms17010044 · Cited by 85
Jyonouchi, H., Zhang, L., & Tomita, Y. (1993) · Nutrition and Cancer · doi:10.1080/01635589309514258 · Cited by 83
Chou, H.-Y., Chelsea, L., Pan, J., Wen, Z., Huang, S., Lan, J. C., Liu, W., Hour, T., Hseu, Y., Hwang, B. H., et al. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17060955 · Cited by 80
Davinelli, S., Sapere, N., Visentin, M., Zella, D., & Scapagnini, G. (2013) · Immunity & Ageing · doi:10.1186/1742-4933-10-28 · Cited by 76
Self-citationKo, J., Chen, J., Wang, T., Zheng, H., Chen, W.-C., Chang, P.-Y., & Lin, Y. (2016) · Biochemical Pharmacology · doi:10.1016/j.bcp.2016.02.016 · Cited by 73
Rüfer, C. E., Moeseneder, J., Briviba, K., Rechkemmer, G., & Bub, A. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507845521 · Cited by 72
EFSA Panel on Dietetic Products, N. A. A. (. (2014) · EFSA Journal · doi:10.2903/j.efsa.2014.3757 · Cited by 66
Astaxanthin stimulates cell-mediated and humoral immune responses in cats
Park, J. S., Mathison, B. D., Hayek, M. G., Massimino, S., Reinhart, G. A., & Chew, B. P. (2011) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2011.08.019 · Cited by 64
Terazawa, S., Nakajima, H., Mori, S., Niwano, T., & Imokawa, G. (2012) · Experimental Dermatology · doi:10.1111/j.1600-0625.2012.01496.x · Cited by 60
Über die Farbstoffe des Hummers (Astacus gammarus L.)
Kuhn, R. J., & Sörensen, N. A. (1938) · Angewandte Chemie · doi:10.1002/ange.19380512703 · Cited by 57
Cytoprotective Polyphenols Against Chronological Skin Aging and Cutaneous Photodamage
Davinelli, S., Bertoglio, J. C., Polimeni, A., & Scapagnini, G. (2018) · Current Pharmaceutical Design · doi:10.2174/1381612823666171109102426 · Cited by 57
Self-citationAstaxanthin reduces matrix metalloproteinase expression in human chondrocytes
Chen, W., Xiong, Y., Shi, Y., Hu, P., Bao, J., & Wu, L. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2013.12.007 · Cited by 56
Astaxanthin Supplementation Does Not Augment Fat Use or Improve Endurance Performance
RES, P. T., Cermak, N. M., Stinkens, R., TOLLAKSON, T. J., Haenen, G. R. M. M., Bast, A., & van Loon, L. J. C. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31827fddc4 · Cited by 50
(FEEDAP), E. P. O. A. A. P. O. S. U. I. A. F. (2014) · EFSA Journal · doi:10.2903/j.efsa.2014.3724 · Cited by 46
Davinelli, S., Chiosi, F., Marco, R. D., Costagliola, C., & Scapagnini, G. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/2825703 · Cited by 37
Self-citationAltered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat
Davinelli, S., Scapagnini, G., Denaro, F., Calabrese, V., Benedetti, F., Krishnan, S., Curreli, S., Bryant, J., & Zella, D. (2014) · Biogerontology · doi:10.1007/s10522-014-9511-6 · Cited by 35
Self-citationSynergistic Effect of L-Carnosine and EGCG in the Prevention of Physiological Brain Aging
Davinelli, S., Marco, R. D., Bracale, R., Quattrone, A., Zella, D., & Scapagnini, G. (2013) · Current Pharmaceutical Design · doi:10.2174/1381612811319150007 · Cited by 30
Self-citation
Flagged first, then by citations
Research works printed but not linked: 4
- Seki, 2001, Effects of astaxanthin from Haematococcus pluvialis on human skin, Fragr. J., 12, 98
- Yamahita, 1995, Suppression of post-UVB hyperpigmentation by topical astaxanthin from krill, Fragr. J., 14, 180
- Yamahita, 2006, The Effect of a dietary supplement containing astaxanthin on skin condition, Carotenoid Sci., 10, 91
- Tominaga, 2009, Cosmetic effects of astaxanthin for all layers of skin, Food Style, 13, 25
Cited by
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Self-citationPlant-Derived Antioxidants: Significance in Skin Health and the Ageing Process
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Metadata
- Authors
- Davinelli, S., Nielsen, M. E., & Scapagnini, G.
- Affiliations
- University of Molise (IT)
- FB Dermatology, Borupvang 5C, 2750 Ballerup, Denmark
- Corresponding author
- Davinelli, Sergio
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2018-04-22
- Volume
- 10
- Issue
- 4
- Pages
- 522
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC5946307
- OpenAlex
- W2802266362
- Cited by
- 473
- References
- 84
- Citations by year
- 2026: 38 · 2025: 63 · 2024: 57 · 2023: 66 · 2022: 66 · 2021: 96 · 2020: 56 · 2019: 26 · 2018: 5
- FWCI
- 7.43
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Archivio Istituzionale della Ricerca - Università degli Studi del Molise (submittedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Keywords
- astaxanthin, xanthophyll carotenoids, skin health, skin repair, Haematococcus pluvialis, microalgae cultivation, nutraceuticals, photoprotection, antioxidant activity, anti-inflammatory activity, skin homeostasis, dietary supplementation
- MeSH terms
- Animals, Anti-Inflammatory Agents, Antioxidants, Biological Availability, DNA Damage, DNA Repair, Humans, Skin, Skin Aging, Dietary Supplements, Xanthophylls
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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