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The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Obesity in Adulthood and Its Consequences for Life Expectancy: A Life-Table Analysis

Open access
Peeters, Anna, Barendregt, Jan J., Willekens, Frans, Mackenbach, Johan P., Mamun, Abdullah Al, Bonneux, Luc, and for NEDCOM, the Netherlands Epidemiology and Demography Compression of Morbidity Research Group*·2003·Annals of Internal Medicine
DOI 10.7326/0003-4819-138-1-200301070-00008
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Abstract

BACKGROUND: Overweight and obesity in adulthood are linked to an increased risk for death and disease. Their potential effect on life expectancy and premature death has not yet been described. OBJECTIVE: To analyze reductions in life expectancy and increases in premature death associated with overweight and obesity at 40 years of age. DESIGN: Prospective cohort study. SETTING: The Framingham Heart Study with follow-up from 1948 to 1990. PARTICIPANTS: 3457 Framingham Heart Study participants who were 30 to 49 years of age at baseline. MEASUREMENTS: Mortality rates specific for age and body mass index group (normal weight, overweight, or obese at baseline) were derived within sex and smoking status strata. Life expectancy and the probability of death before 70 years of age were analyzed by using life tables. RESULTS: Large decreases in life expectancy were associated with overweight and obesity. Forty-year-old female nonsmokers lost 3.3 years and 40-year-old male nonsmokers lost 3.1 years of life expectancy because of overweight. Forty-year-old female nonsmokers lost 7.1 years and 40-year-old male nonsmokers lost 5.8 years because of obesity. Obese female smokers lost 7.2 years and obese male smokers lost 6.7 years of life expectancy compared with normal-weight smokers. Obese female smokers lost 13.3 years and obese male smokers lost 13.7 years compared with normal-weight nonsmokers. Body mass index at ages 30 to 49 years predicted mortality after ages 50 to 69 years, even after adjustment for body mass index at age 50 to 69 years. CONCLUSIONS: Obesity and overweight in adulthood are associated with large decreases in life expectancy and increases in early mortality. These decreases are similar to those seen with smoking. Obesity in adulthood is a powerful predictor of death at older ages. Because of the increasing prevalence of obesity, more efficient prevention and treatment should become high priorities in public health.

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Metadata

Authors
Peeters, A., Barendregt, J. J., Willekens, F., Mackenbach, J. P., Mamun, A. A., Bonneux, L., & and for NEDCOM, T. N. E. A. D. C. O. M. R. G.
Venue
Annals of Internal Medicine
Publisher
American College of Physicians
Published
2003-01-07
Volume
138
Issue
1
Pages
24-32
ISSN
  • 0003-4819 (ISSN-L)
  • 1539-3704
DOI
10.7326/0003-4819-138-1-200301070-00008
OpenAlex
W2151226564
Cited by
1,479
References
6
FWCI
78.47
Type
journal article
Language
en
Open access
green

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