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MicroRNA-9 controls dendritic development by targeting REST

Giusti, Sebastian A, Vogl, Annette M, Brockmann, Marisa M, Vercelli, Claudia A, Rein, Martin L, Trümbach, Dietrich, Wurst, Wolfgang, Cazalla, Demian +3 more·2014·eLife
DOI 10.7554/elife.02755PMC PMC4235007
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Abstract

MicroRNAs (miRNAs) are conserved noncoding RNAs that function as posttranscriptional regulators of gene expression. miR-9 is one of the most abundant miRNAs in the brain. Although the function of miR-9 has been well characterized in neural progenitors, its role in dendritic and synaptic development remains largely unknown. In order to target miR-9 in vivo, we developed a transgenic miRNA sponge mouse line allowing conditional inactivation of the miR-9 family in a spatio-temporal-controlled manner. Using this novel approach, we found that miR-9 controls dendritic growth and synaptic transmission in vivo. Furthermore, we demonstrate that miR-9-mediated downregulation of the transcriptional repressor REST is essential for proper dendritic growth.

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  1. Akerblom M Sachdeva R Jakobsson J 2012 Functional studies of microRNAs in neural stem cells: problems and perspectives. Frontiers in Neuroscience 6: 14. doi: 10.3389/fnins.2012.00014. 22347160 PMC3273711 · DOI
  2. Akerblom M Sachdeva R Quintino L Wettergren EE Chapman KZ Manfre G Lindvall O Lundberg C Jakobsson J 2013 Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9. Nature Communications 4: 1770. doi: 10.1038/ncomms2801. 23612311 · DOI · Paper page
  3. Ameres SL Horwich MD Hung JH Xu J Ghildiyal M Weng Z Zamore PD 2010 Target RNA-directed trimming and tailing of small silencing RNAs. Science 328: 1534– 1539. doi: 10.1126/science.1187058. 20558712 PMC2902985 · DOI · Paper page
  4. Andres ME Burger C Peral-Rubio MJ Battaglioli E Anderson ME Grimes J Dallman J Ballas N Mandel G 1999 CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proceedings of the National Academy of Sciences of USA 96: 9873– 9878. doi: 10.1073/pnas.96.17.9873. PMC22303 10449787 · DOI · Paper page
  5. Aoki H Hara A Era T Kunisada T Yamada Y 2012 Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development 139: 667– 677. doi: 10.1242/dev.072272. 22241837 · DOI
  6. Ballas N Grunseich C Lu DD Speh JC Mandel G 2005 REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121: 645– 657. doi: 10.1016/j.cell.2005.03.013. 15907476 · DOI · Paper page
  7. Ballas N Mandel G 2005 The many faces of REST oversee epigenetic programming of neuronal genes. Current Opinion in Neurobiology 15: 500– 506. doi: 10.1016/j.conb.2005.08.015. 16150588 · DOI
  8. Barnes AP Polleux F 2009 Establishment of axon-dendrite polarity in developing neurons. Annual Review of Neuroscience 32: 347– 381. doi: 10.1146/annurev.neuro.31.060407.125536. PMC3170863 19400726 · DOI · Paper page
  9. Bartel DP 2009 MicroRNAs: target recognition and regulatory functions. Cell 136: 215– 233. doi: 10.1016/j.cell.2009.01.002. 19167326 PMC3794896 · DOI · Paper page
  10. Bonev B Pisco A Papalopulu N 2011 MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis. Developmental Cell 20: 19– 32. doi: 10.1016/j.devcel.2010.11.018. 21238922 PMC3361082 · DOI
  11. Bushati N Cohen SM 2007 microRNA functions. Annual Review of Cell and Developmental Biology 23: 175– 205. doi: 10.1146/annurev.cellbio.23.090506.123406. 17506695 · DOI · Paper page
  12. Caceres A Ye B Dotti CG 2012 Neuronal polarity: demarcation, growth and commitment. Current Opinion in Cell Biology 24: 547– 553. doi: 10.1016/j.ceb.2012.05.011. 22726583 PMC3425660 · DOI
  13. Care A Catalucci D Felicetti F Bonci D Addario A Gallo P Bang ML Segnalini P Gu Y Dalton ND Elia L Latronico MV Høydal M Autore C Russo MA Dorn GW II Ellingsen O Ruiz-Lozano P Peterson KL Croce CM Peschle C Condorelli G 2007 MicroRNA-133 controls cardiac hypertrophy. Nature Medicine 13: 613– 618. doi: 10.1038/nm1582. 17468766 · DOI
  14. Chen CM Krohn J Bhattacharya S Davies B 2011 A comparison of exogenous promoter activity at the ROSA26 locus using a PhiiC31 integrase mediated cassette exchange approach in mouse ES cells. PLOS ONE 6: e23376. doi: 10.1371/journal.pone.0023376. 21853122 PMC3154917 · DOI
  15. Chen ZF Paquette AJ Anderson DJ 1998 NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis. Nature Genetics 20: 136– 142. doi: 10.1038/2431. 9771705 · DOI
  16. Coolen M Katz S Bally-Cuif L 2013 miR-9: a versatile regulator of neurogenesis. Frontiers in Neuroscience 7: 220. doi: 10.3389/fncel.2013.00220. 24312010 PMC3834235 · DOI · Paper page
  17. Coolen M Thieffry D Drivenes O Becker TS Bally-Cuif L 2012 miR-9 controls the timing of neurogenesis through the direct inhibition of antagonistic factors. Developmental Cell 22: 1052– 1064. doi: 10.1016/j.devcel.2012.03.003. 22595676 · DOI
  18. Dajas-Bailador F Bonev B Garcez P Stanley P Guillemot F Papalopulu N 2012 microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons. Nature Neuroscience 15: 697– 699. doi: 10.1038/nn.3082. 22484572 · DOI
  19. Delaloy C Liu L Lee JA Su H Shen F Yang GY Young WL Ivey KN Gao FB 2010 MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell 6: 323– 335. doi: 10.1016/j.stem.2010.02.015. 20362537 PMC2851637 · DOI · Paper page
  20. Dieni S Rees S 2003 Dendritic morphology is altered in hippocampal neurons following prenatal compromise. Journal of Neurobiology 55: 41– 52. doi: 10.1002/neu.10194. 12605458 · DOI
  21. Dotti CG Sullivan CA Banker GA 1988 The establishment of polarity by hippocampal-neurons in culture. Journal of Neuroscience 8: 1454– 1468. 3282038 PMC6569279
  22. Ebert MS Neilson JR Sharp PA 2007 MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nature Methods 4: 721– 726. doi: 10.1038/nmeth1079. 17694064 PMC3857099 · DOI · Paper page
  23. Feng G Mellor RH Bernstein M Keller-Peck C Nguyen QT Wallace M Nerbonne JM Lichtman JW Sanes JR 2000 Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28: 41– 51. doi: 10.1016/S0896-6273(00)00084-2. 11086982 · DOI · Paper page
  24. Fiore R Khudayberdiev S Christensen M Siegel G Flavell SW Kim TK Greenberg ME Schratt G 2009 Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. The EMBO Journal 28: 697– 710. doi: 10.1038/emboj.2009.10. 19197241 PMC2647767 · DOI · Paper page
  25. Gao Z Ure K Ding P Nashaat M Yuan L Ma J Hammer RE Hsieh J 2011 The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells. The Journal of Neuroscience 31: 9772– 9786. doi: 10.1523/JNEUROSCI.1604-11.2011. 21715642 PMC3365553 · DOI
  26. Gentner B Schira G Giustacchini A Amendola M Brown BD Ponzoni M Naldini L 2009 Stable knockdown of microRNA in vivo by lentiviral vectors. Nature Methods 6: 63– 66. doi: 10.1038/nmeth.1277. 19043411 · DOI
  27. Giraldez AJ Cinalli RM Glasner ME Enright AJ Thomson JM Baskerville S Hammond SM Bartel DP Schier AF 2005 MicroRNAs regulate brain morphogenesis in zebrafish. Science 308: 833– 838. doi: 10.1126/science.1109020. 15774722 · DOI · Paper page
  28. Goslin K Asmussen H Banker G 1998 Rat hippocampal neurons in low-density culture. In: Culturing Nerve Cells, Rat hippocampal neurons in low-density culture. Banker G Goslin K, editors. Camebridge, Massachusetts: MIT Press p. 339– 370.
  29. Han K Gennarino VA Lee Y Pang K Hashimoto-Torii K Choufani S Raju CS Oldham MC Weksberg R Rakic P Liu Z Zoghbi HY 2013 Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p. Genes & Development 27: 485– 490. doi: 10.1101/gad.207456.112. 23431031 PMC3605462 · DOI
  30. Hand R Bortone D Mattar P Nguyen L Heng JI Guerrier S Boutt E Peters E Barnes AP Parras C Schuurmans C Guillemot F Polleux F 2005 Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex. Neuron 48: 45– 62. doi: 10.1016/j.neuron.2005.08.032. 16202708 · DOI
  31. Haramati S Chapnik E Sztainberg Y Eilam R Zwang R Gershoni N McGlinn E Heiser PW Wills AM Wirguin I Rubin LL Misawa H Tabin CJ Brown R Jnr Chen A Hornstein E 2010 miRNA malfunction causes spinal motor neuron disease. Proceedings of the National Academy of Sciences of USA 107: 13111– 13116. doi: 10.1073/pnas.1006151107. PMC2919953 20616011 · DOI
  32. Hering H Sheng M 2001 Dendritic spines: structure, dynamics and regulation. Nature Reviews Neuroscience 2: 880– 888. doi: 10.1038/35104061. 11733795 · DOI · Paper page
  33. Hitz C Wurst W Kuhn R 2007 Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference. Nucleic Acids Research 35: e90. doi: 10.1038/35104061. 17586814 PMC1919482 · DOI · Paper page
  34. Horch HW Katz LC 2002 BDNF release from single cells elicits local dendritic growth in nearby neurons. Nature Neuroscience 5: 1177– 1184. doi: 10.1038/nn927. 12368805 · DOI
  35. Jan YN Jan LY 2003 The control of dendrite development. Neuron 40: 229– 242. doi: 10.1016/S0896-6273(03)00631-7. 14556706 · DOI
  36. Jiang M Chen G 2006 High Ca(2+)-phosphate transfection efficiency in low-density neuronal cultures. Nature Protocols 1: 695– 700. doi: 10.1038/nprot.2006.86. 17406298 · DOI
  37. Jorgensen HF Terry A Beretta C Pereira CF Leleu M Chen ZF Kelly C Merkenschlager M Fisher AG 2009 REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells. Development 136: 715– 721. doi: 10.1242/dev.028548. 19201947 PMC2685939 · DOI · Paper page
  38. Kawabe H Neeb A Dimova K Young SM Jnr Takeda M Katsurabayashi S Mitkovski M Malakhova OA Zhang DE Umikawa M Kariya K Goebbels S Nave KA Rosenmund C Jahn O Rhee J Brose N 2010 Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron 65: 358– 372. doi: 10.1016/j.neuron.2010.01.007. 20159449 PMC2825371 · DOI
  39. Kawauchi T Chihama K Nishimura YV Nabeshima Y Hoshino M 2005 MAP1B phosphorylation is differentially regulated by Cdk5/p35, Cdk5/p25, and JNK. Biochemical and Biophysical Research Communications 331: 50– 55. doi: 10.1016/j.bbrc.2005.03.132. 15845356 · DOI
  40. Kluiver J Gibcus JH Hettinga C Adema A Richter MK Halsema N Slezak-Prochazka I Ding Y Kroesen BJ van den Berg A 2012 Rapid generation of microRNA sponges for microRNA inhibition. PLOS ONE 7: e29275. doi: 10.1371/journal.pone.0029275. 22238599 PMC3253070 · DOI
  41. Koch JC Barski E Lingor P Bahr M Michel U 2011 Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression. The FEBS Journal 278: 3472– 3483. doi: 10.1111/j.1742-4658.2011.08269.x. 21790997 · DOI
  42. Kolb B Stewart J Sutherland RJ 1997 Recovery of function is associated with increased spine density in cortical pyramidal cells after frontal lesions and/or noradrenaline depletion in neonatal rats. Behavioural Brain Research 89: 61– 70. doi: 10.1016/S0166-4328(97)00058-2. 9475615 · DOI
  43. Kruger J Rehmsmeier M 2006 RNAhybrid: microRNA target prediction easy, fast and flexible. Nucleic Acids Research 34: W451– W454. doi: 10.1093/nar/gkl243. 16845047 PMC1538877 · DOI · Paper page
  44. Kuwabara T Hsieh J Nakashima K Taira K Gage FH 2004 A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell 116: 779– 793. doi: 10.1016/S0092-8674(04)00248-X. 15035981 · DOI · Paper page
  45. Laemmli UK 1970 Cleavage of structural proteins during assembly of head of bacteriophage-T4. Nature 227: 680– 685. doi: 10.1016/S0092-8674(04)00248-X. 5432063 · DOI · Paper page
  46. Lagos-Quintana M Rauhut R Lendeckel W Tuschl T 2001 Identification of novel genes coding for small expressed RNAs. Science 294: 853– 858. doi: 10.1126/science.1064921. 11679670 · DOI · Paper page
  47. Lagos-Quintana M Rauhut R Yalcin A Meyer J Lendeckel W Tuschl T 2002 Identification of tissue-specific microRNAs from mouse. Current Biology 12: 735– 739. doi: 10.1016/S0960-9822(02)00809-6. 12007417 · DOI · Paper page
  48. Leucht C Stigloher C Wizenmann A Klafke R Folchert A Bally-Cuif L 2008 MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nature Neuroscience 11: 641– 648. doi: 10.1038/nn.2115. 18454145 · DOI · Paper page
  49. Liu DZ Ander BP Tian Y Stamova B Jickling GC Davis RR Sharp FR 2012 Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells. Gene 495: 120– 127. doi: 10.1016/j.gene.2011.12.041. 22244746 · DOI · Paper page
  50. Liu GD Zhang H Wang L Han Q Zhou SF Liu P 2013a Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells. International Journal of Ophthalmology 6: 280– 285. doi: 10.3980/j.issn.2222-3959.2013.03.05. 23826519 PMC3693006 · DOI
  51. Liu Y Zhao Z Yang F Gao Y Song J Wan Y 2013b microRNA-181a is involved in insulin-like growth factor-1-mediated regulation of the transcription factor CREB1. Journal of Neurochemistry 126: 771– 780. doi: 10.1111/jnc.12370. 23865718 · DOI
  52. London M Hausser M 2005 Dendritic computation. Annual Review of Neuroscience 28: 503– 532. doi: 10.1146/annurev.neuro.28.061604.135703. 16033324 · DOI · Paper page
  53. Loya CM Lu CS Van VD Fulga TA 2009 Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms. Nature Methods 6: 897– 903. doi: 10.1038/nmeth.1402. 19915559 PMC3183579 · DOI
  54. Luxenhofer G Helmbrecht MS Langhoff J Giusti SA Refojo D Huber AB 2014 MicroRNA-9 promotes the switch from early-born to late-born motor neuron populations by regulating Onecut transcription factor expression. Developmental Biology 386: 358– 370. doi: 10.1016/j.ydbio.2013.12.023. 24374159 · DOI
  55. Ma F Xu S Liu X Zhang Q Xu X Liu M Hua M Li N Yao H Cao X 2011 The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma. Nature Immunology 12: 861– 869. doi: 10.1038/ni.2073. 21785411 · DOI
  56. Madisen L Zwingman TA Sunkin SM Oh SW Zariwala HA Gu H Ng LL Palmiter RD Hawrylycz MJ Jones AR Lein ES Zeng H 2010 A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nature Neuroscience 13: 133– 140. doi: 10.1038/nn.2467. PMC2840225 20023653 · DOI · Paper page
  57. Magill ST Cambronne XA Luikart BW Lioy DT Leighton BH Westbrook GL Mandel G Goodman RH 2010 microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. Proceedings of the National Academy of Sciences of USA 107: 20382– 20387. doi: 10.1073/pnas.1015691107. PMC2996687 21059906 · DOI
  58. Mumm JS Williams PR Godinho L Koerber A Pittman AJ Roeser T Chien CB Baier H Wong RO 2006 In vivo imaging reveals dendritic targeting of laminated afferents by zebrafish retinal ganglion cells. Neuron 52: 609– 621. doi: 10.1016/j.neuron.2006.10.004. 17114046 PMC1716713 · DOI
  59. Nadeau H Lester HA 2002 NRSF causes cAMP-sensitive suppression of sodium current in cultured hippocampal neurons. Journal of Neurophysiology 88: 409– 421. 12091564
  60. Olena AF Patton JG 2010 Genomic organization of microRNAs. Journal of Cellular Physiology 222: 540– 545. doi: 10.1002/jcp.21993. 20020507 PMC4028663 · DOI
  61. Ooi L Wood IC 2007 Chromatin crosstalk in development and disease: lessons from REST. Nature Reviews Genetics 8: 544– 554. doi: 10.1038/nrg2100. 17572692 · DOI
  62. Otaegi G Pollock A Hong J Sun T 2011 MicroRNA miR-9 modifies motor neuron columns by a tuning regulation of FoxP1 levels in developing spinal cords. The Journal of Neuroscience 31: 809– 818. doi: 10.1523/JNEUROSCI.4330-10.2011. 21248104 PMC3040495 · DOI
  63. Parrish JZ Emoto K Kim MD Jan YN 2007 Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields. Annual Review of Neuroscience 30: 399– 423. doi: 10.1146/annurev.neuro.29.051605.112907. 17378766 · DOI
  64. Parrish JZ Xu P Kim CC Jan LY Jan YN 2009 The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron 63: 788– 802. doi: 10.1016/j.neuron.2009.08.006. 19778508 PMC2772869 · DOI
  65. Pathania M Torres-Reveron J Yan L Kimura T Lin TV Gordon V Teng ZQ Zhao X Fulga TA Van VD Bordey A 2012 miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons. PLOS ONE 7: e38174. doi: 10.1371/journal.pone.0038174. 22693596 PMC3364964 · DOI
  66. Polleux F Morrow T Ghosh A 2000 Semaphorin 3A is a chemoattractant for cortical apical dendrites. Nature 404: 567– 573. doi: 10.1038/35007001. 10766232 · DOI
  67. Qin JY Zhang L Clift KL Hulur I Xiang AP Ren BZ Lahn BT 2010 Systematic comparison of constitutive promoters and the doxycycline-inducible promoter. PLOS ONE 5: e10611. doi: 10.1371/journal.pone.0010611. 20485554 PMC2868906 · DOI
  68. Rajan I Cline HT 1998 Glutamate receptor activity is required for normal development of tectal cell dendrites in vivo. The Journal of Neuroscience 18: 7836– 7846. 9742152 PMC6793000
  69. Refojo D Schweizer M Kuehne C Ehrenberg S Thoeringer C Vogl AM Dedic N Schumacher M von WG Avrabos C Touma C Engblom D Schutz G Nave KA Eder M Wotjak CT Sillaber I Holsboer F Wurst W Deussing JM 2011 Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science 333: 1903– 1907. doi: 10.1126/science.1202107. 21885734 · DOI
  70. Rodriguez A Griffiths-Jones S Ashurst JL Bradley A 2004 Identification of mammalian microRNA host genes and transcription units. Genome Research 14: 1902– 1910. doi: 10.1101/gr.2722704. 15364901 PMC524413 · DOI · Paper page
  71. Saito T 2006 In vivo electroporation in the embryonic mouse central nervous system. Nature Protocols 1: 1552– 1558. doi: 10.1038/nprot.2006.276. 17406448 · DOI
  72. Sauvageau M Goff LA Lodato S Bonev B Groff AF Gerhardinger C Sanchez-Gomez DB Hacisuleyman E Li E Spence M Liapis SC Mallard W Morse M Swerdel MR D'Ecclessis MF Moore JC Lai V Gong G Yancopoulos GD Frendewey D Kellis M Hart RP Valenzuela DM Arlotta P Rinn JL 2013 Multiple knockout mouse models reveal lincRNAs are required for life and brain development. eLife 2: e01749. doi: 10.7554/eLife.01749. 24381249 PMC3874104 · DOI
  73. Schoenherr CJ Anderson DJ 1995 The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 267: 1360– 1363. doi: 10.1126/science.7871435. 7871435 · DOI
  74. Schratt GM Tuebing F Nigh EA Kane CG Sabatini ME Kiebler M Greenberg ME 2006 A brain-specific microRNA regulates dendritic spine development. Nature 439: 283– 289. doi: 10.1038/nature04367. 16421561 · DOI · Paper page
  75. Senyuk V Zhang Y Liu Y Ming M Premanand K Zhou L Chen P Chen J Rowley JD Nucifora G Qian Z 2013 Critical role of miR-9 in myelopoiesis and EVI1-induced leukemogenesis. Proceedings of the National Academy of Sciences of USA 110: 5594– 5599. doi: 10.1073/pnas.1302645110. PMC3619279 23509296 · DOI
  76. Shibata M Nakao H Kiyonari H Abe T Aizawa S 2011 MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. The Journal of Neuroscience 31: 3407– 3422. doi: 10.1523/JNEUROSCI.5085-10.2011. 21368052 PMC6623912 · DOI · Paper page
  77. Simó S Cooper JA 2012 Regulation of dendritic branching by Cdc42 GAPs. Genes & Development 26: 1653– 1658. doi: 10.1101/gad.199034.112. 22855828 PMC3418583 · DOI
  78. Soriano P 1999 Generalized lacZ expression with the ROSA26 Cre reporter strain. Nature Genetics 21: 70– 71. doi: 10.1038/5007. 9916792 · DOI
  79. Spruston N 2008 Pyramidal neurons: dendritic structure and synaptic integration. Nature Reviews Neuroscience 9: 206– 221. doi: 10.1038/nrn2286. 18270515 · DOI · Paper page
  80. Takemoto-Kimura S Ageta-Ishihara N Nonaka M Adachi-Morishima A Mano T Okamura M Fujii H Fuse T Hoshino M Suzuki S Kojima M Mishina M Okuno H Bito H 2007 Regulation of dendritogenesis via a lipid-raft-associated Ca2+/calmodulin-dependent protein kinase CLICK-III/CaMKIgamma. Neuron 54: 755– 770. doi: 10.1016/j.neuron.2007.05.021. 17553424 · DOI
  81. Tronche F Kellendonk C Kretz O Gass P Anlag K Orban PC Bock R Klein R Schutz G 1999 Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nature Genetics 23: 99– 103. doi: 10.1038/12703. 10471508 · DOI
  82. Urbanska M Blazejczyk M Jaworski J 2008 Molecular basis of dendritic arborization. Acta Neurobiologiae Experimentalis 68: 264– 288. 18511961
  83. Wayman GA Davare M Ando H Fortin D Varlamova O Cheng HY Marks D Obrietan K Soderling TR Goodman RH Impey S 2008 An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proceedings of the National Academy of Sciences of USA 105: 9093– 9098. doi: 10.1073/pnas.0803072105. PMC2449370 18577589 · DOI · Paper page
  84. Whitford KL Marillat V Stein E Goodman CS Tessier-Lavigne M Chedotal A Ghosh A 2002 Regulation of cortical dendrite development by Slit-Robo interactions. Neuron 33: 47– 61. doi: 10.1016/S0896-6273(01)00566-9. 11779479 · DOI
  85. Witkos TM Koscianska E Krzyzosiak WJ 2011 Practical Aspects of microRNA Target Prediction. Current Molecular Medicine 11: 93– 109. doi: 10.2174/156652411794859250. 21342132 PMC3182075 · DOI
  86. Yamamoto M Ueda R Takahashi K Saigo K Uemura T 2006 Control of axonal sprouting and dendrite branching by the Nrg-Ank complex at the neuron-glia interface. Current Biology 16: 1678– 1683. doi: 10.1016/j.cub.2006.06.061. 16920632 · DOI
  87. Yao MJ Chen G Zhao PP Lu MH Jian J Liu MF Yuan XB 2012 Transcriptome analysis of microRNAs in developing cerebral cortex of rat. BMC Genomics 13: 232. doi: 10.1186/1471-2164-13-232. 22691069 PMC3441217 · DOI
  88. Yoo AS Staahl BT Chen L Crabtree GR 2009 MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature 460: 642– 646. doi: 10.1038/nature08139. 19561591 PMC2921580 · DOI · Paper page
  89. Zhao C Sun G Li S Shi Y 2009 A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nature Structural & Molecular Biology 16: 365– 371. doi: 10.1038/nsmb.1576. PMC2667220 19330006 · DOI · Paper page

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Authors
Giusti, S. A., Vogl, A. M., Brockmann, M. M., Vercelli, C. A., Rein, M. L., Trümbach, D., Wurst, W., Cazalla, D., Stein, V., Deussing, J. M., & Refojo, D.
Affiliations
  • Department of Molecular Neurobiology, Max Planck Institute of Psychiatry, Munich, Germany
  • Department of Molecular Neurobiology, Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)-CONICET-Partner Institute of the Max Planck Society, Buenos Aires, Argentina
  • Department of Neurobiology of Stress and Neurogenetics, Max Planck Institute of Psychiatry, Munich, Germany
  • Institute of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany
  • Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, United States
  • Institute of Physiology, University of Bonn, Bonn, Germany
Venue
eLife
Publisher
eLife Sciences Publications, Ltd
Published
2014-11-18
Volume
3
ISSN
2050-084X
DOI
10.7554/elife.02755
PMC
PMC4235007
Cited by
102
References
7
Language
en
Licence
Funders
  • European Union (SyBoSS FP7-Health-F4-2010-242129)
  • Bavarian State Ministry of Education, Science and Arts (Bavarian Research Network - ForIPs)
  • Bundesministerium für Bildung und Forschung (FKZ 01GN1009C, FKZ 01GS08151, FKZ 01GS08155)
  • Max-Planck-Gesellschaft (Institute of Psychiatry)

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