The Relationship Between Aberrant Neuronal Activation in the Pregenual Anterior Cingulate, Altered Glutamatergic Metabolism, and Anhedonia in Major Depression

An inventory for measuring depression

BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works

A rating scale for depression

Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817 · see citing works

A default mode of brain function

Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190 · see citing works

Region of interest analysis using an SPM toolbox

Brett, M. (2002) · NeuroImage · Cited by 2,273 · see citing works

Resting-State Functional Connectivity in Major Depression: Abnormally Increased Contributions from Subgenual Cingulate Cortex and Thalamus

Greicius, M. D., Flores, B. H., Menon, V., Glover, G. H., Solvason, H. B., Kenna, H., Reiss, A. L., & Schatzberg, A. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.020 · Cited by 2,214 · see citing works

Neurobiology of emotion perception II: implications for major psychiatric disorders

Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00171-9 · Cited by 1,736 · see citing works

BRAIN WORK AND BRAIN IMAGING

Raichle, M. E., & Mintun, M. A. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112819 · Cited by 1,630 · see citing works

Glial reduction in the subgenual prefrontal cortex in mood disorders

Öngür, D., Drevets, W. C., & Price, J. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13290 · Cited by 1,525 · see citing works

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression∗∗See accompanying Editorial, in this issue.

Rajkowska, G., Miguel-Hidalgo, J. J., Wei, J., Dilley, G., Pittman, S. D., Meltzer, H. Y., Overholser, J. C., Roth, B. L., & Stockmeier, C. A. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00041-4 · Cited by 1,477 · see citing works

N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology

MOFFETT, J., Ross, B., Arun, P., Madhavarao, C. N., & Namboodiri, A. M. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2006.12.003 · Cited by 1,413 · see citing works

The cellular neurobiology of depression

Manji, H. K., Drevets, W. C., & Charney, D. S. (2001) · Nature Medicine · doi:10.1038/87865 · Cited by 1,182 · see citing works

Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment

Mayberg, H. S. (2003) · British Medical Bulletin · doi:10.1093/bmb/65.1.193 · Cited by 1,166 · see citing works

Cingulate function in depression: a potential predictor of treatment response

Mayberg, H. S., Brannan, S. K., Mahurin, R. K., Jerabek, P. A., Brickman, J. S., Tekell, J. L., Silva, J. A., McGinnis, S., Glass, T. G., Martin, C. C., et al. (1997) · NeuroReport · doi:10.1097/00001756-199703030-00048 · Cited by 1,029 · see citing works

A meta‐analytic study of changes in brain activation in depression

Fitzgerald, P. B., Laird, A. R., Maller, J., & Daskalakis, Z. J. (2008) · Human Brain Mapping · doi:10.1002/hbm.20426 · Cited by 903 · see citing works

Reduced Prefrontal Glutamate/Glutamine and γ-Aminobutyric Acid Levels in Major Depression Determined Using Proton Magnetic Resonance Spectroscopy

Hasler, G., van der Veen, J. W., Tumonis, T., Meyers, N., Shen, J., & Drevets, W. C. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.2.193 · Cited by 846 · see citing works

Subtype-Specific Alterations of γ-Aminobutyric Acid and Glutamatein Patients With Major Depression

Sanacora, G., Gueorguieva, R. V., Epperson, C. N., Wu, Y., Appel, M., Rothman, D. L., Krystal, J. H., & Mason, G. F. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.7.705 · Cited by 796 · see citing works

Reduced Glial Cell Density and Neuronal Size in the Anterior Cingulate Cortex in Major Depressive Disorder

Cotter, D., Mackay, D., Landau, S., Kerwin, R., & Everall, I. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.6.545 · Cited by 766 · see citing works

When zero is not zero: the problem of ambiguous baseline conditions in fMRI

Stark, C. E. L., & Squire, L. R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.221462998 · Cited by 724 · see citing works

Computer Simulations in Magnetic Resonance. An Object-Oriented Programming Approach

Smith, S. A., Levante, T. O., Meier, B. H., & Ernst, R. R. (1994) · Journal of Magnetic Resonance Series A · doi:10.1006/jmra.1994.1008 · Cited by 711 · see citing works

Limbic-frontal circuitry in major depression: a path modeling metanalysis

Seminowicz, D. A., Mayberg, H. S., McIntosh, A. R., Goldapple, K., Kennedy, S., Segal, Z., & Rafi-Tari, S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.01.015 · Cited by 710 · see citing works

Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: An fMRI study in severe major depressive disorder

Grimm, S., Beck, J., Schuepbach, D., Hell, D., Boesiger, P., Bermpohl, F., Niehaus, L., Boeker, H., & Northoff, G. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.05.033 · Cited by 686 · see citing works

Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium

Uranova, N. A., Vostrikov, V. M., Orlovskaya, D. D., & Rachmanova, V. I. (2004) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00181-6 · Cited by 659 · see citing works

Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

Choudary, P. V., Molnar, M., Evans, S. J., Tomita, H., Li, J., Vawter, M. P., Myers, R., Bunney, W. E., Akil, H., Watson, S. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507901102 · Cited by 653 · see citing works

The Neural Correlates of Anhedonia in Major Depressive Disorder

Keedwell, P. A., Andrew, C., Williams, S. C. R., Brammer, M. J., & Phillips, M. L. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.05.019 · Cited by 650 · see citing works

Functional anatomical correlates of antidepressant drug treatment assessed using PET measures of regional glucose metabolism

Drevets, W. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00102-5 · Cited by 581 · see citing works

Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression

Johansen-Berg, H., Gutman, D. A., Behrens, T. E. J., Matthews, P. M., Rushworth, M. F. S., Katz, E., Lozano, A. M., & Mayberg, H. S. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm167 · Cited by 561 · see citing works

Lack of Ventral Striatal Response to Positive Stimuli in Depressed Versus Normal Subjects

Epstein, J., Pan, H., Kocsis, J. H., Yang, Y., Butler, T., Chusid, J., Hochberg, H., Murrough, J., Strohmayer, E., Stern, E., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.10.1784 · Cited by 464 · see citing works

Glial reduction in amygdala in major depressive disorder is due to oligodendrocytes

Hamidi, M., Drevets, W. C., & Price, J. L. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.11.006 · Cited by 369 · see citing works

GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI

Northoff, G., Walter, M., Schulte, R. F., Beck, J., Dydak, U., Henning, A., Boeker, H., Grimm, S., & Boesiger, P. (2007) · Nature Neuroscience · doi:10.1038/nn2001 · Cited by 359 · see citing works

Brain Imaging Correlates of Depressive Symptom Severity and Predictors of Symptom Improvement After Antidepressant Treatment

Chen, C.-H., Ridler, K., Suckling, J., Williams, S., Fu, C. H. Y., Merlo-Pich, E., & Bullmore, E. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.018 · Cited by 354 · see citing works

Pattern Classification of Sad Facial Processing: Toward the Development of Neurobiological Markers in Depression

Fu, C. H. Y., Mourão-Miranda, J., Costafreda, S. G., Khanna, A., Marquand, A. F., Williams, S., & Brammer, M. J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.08.020 · Cited by 337 · see citing works

Cramér–Rao bounds: an evaluation tool for quantitation

Cavassila, S., Deval, S., Huegen, C., ORMONDT, D. V., & Graveron‐Demilly, D. (2001) · NMR in Biomedicine · doi:10.1002/nbm.701 · Cited by 333 · see citing works

Sustained Neuronal Activation Raises Oxidative Metabolism to a New Steady-State Level: Evidence from 1 H NMR Spectroscopy in the Human Visual Cortex

Mangia, S., Tkáč, I., Rolf Gruetter, A., de Moortele, P. V., Maraviglia, B., & Uǧurbil, K. (2006) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600401 · Cited by 285 · see citing works

Blunted response to feedback information in depressive illness

Steele, J. D., Kumar, P., & Ebmeier, K. P. (2007) · Brain · doi:10.1093/brain/awm150 · Cited by 261 · see citing works

An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression

Zarate, C. A., Quiroz, J. A., Singh, J. B., Denicoff, K. D., Jesus, G. D., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.023 · Cited by 257 · see citing works

Two-dimensional assessment of cytoarchitecture in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia: evidence for decreased neuronal somal size and increased neuronal density

Chana, G., Landau, S., Beasley, C. L., Everall, I., & Cotter, D. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00114-8 · Cited by 245 · see citing works

Review of 1H magnetic resonance spectroscopy findings in major depressive disorder: A meta-analysis

Yildiz-Yesiloglu, A., & Ankerst, D. P. (2006) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2005.12.004 · Cited by 232 · see citing works

The density and spatial distribution of gabaergic neurons, labelled using calcium binding proteins, in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia

Cotter, D., Landau, S., Beasley, C. L., Stevenson, R. N., Chana, G., MacMillan, L., & Everall, I. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01243-4 · Cited by 211 · see citing works

ProFit: two‐dimensional prior‐knowledge fitting of J‐resolved spectra

Schulte, R. F., & Boesiger, P. (2006) · NMR in Biomedicine · doi:10.1002/nbm.1026 · Cited by 177 · see citing works

Clinical Studies Implementing Glutamate Neurotransmission in Mood Disorders

Sanacora, G., Rothman, D. L., Mason, G. F., & Krystal, J. H. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.018 · Cited by 157 · see citing works

Construct validity of the Beck Depression Inventory in a depressive population

Schotte, C., Maes, M. H. J., Cluydts, R., Doncker, D. D., & Cosyns, P. R. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00094-3 · Cited by 146 · see citing works

Defining the Neural Circuitry of Depression: Toward a New Nosology With Therapeutic Implications

Mayberg, H. S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.01.013 · Cited by 145 · see citing works

Cingulate function in depression.

Larisch, R., Klimke, A., Vosberg, H., Gaebel, W., & Mueller-Gaertner, H. W. (1997) · PubMed · Cited by 94 · see citing works

Hemispheric Differences in Layer III Pyramidal Neurons of the Anterior Language Area

Hayes, T. L., & Lewis, D. A. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540050053015 · Cited by 93 · see citing works

Improved two‐dimensional J‐resolved spectroscopy

Schulte, R. F., Lange, T., Beck, J., Meier, D., & Boesiger, P. (2006) · NMR in Biomedicine · doi:10.1002/nbm.1027 · Cited by 89 · see citing works

Relationship between regional brain metabolism, illness severity and age in depressed subjects

Konarski, J. Z., Kennedy, S. H., McIntyre, R. S., Rafi‐Tari, S., Soczynska, J. K., & Mayberg, H. S. (2007) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2007.02.001 · Cited by 50 · see citing works

Cluster analytic validation of the DSM melancholic depression. The threshold model: integration of quantitative and qualitative distinctions between unipolar depressive subtypes

Schotte, C., Maes, M. H. J., Cluydts, R., & Cosyns, P. R. (1997) · Psychiatry Research · doi:10.1016/s0165-1781(97)00051-6 · Cited by 46 · see citing works

In vivo proton magnetic resonance spectroscopy in patients with mood disorders: A technically oriented review

Capizzano, A. A., Jorge, R. E., Ación, L., & Robinson, R. G. (2007) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.21144 · Cited by 43 · see citing works

The biochemistry of dysfunctional emotions: proton MR spectroscopic findings in major depressive disorder

Ende, G., Demirakça, T., & Tost, H. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)56027-3 · Cited by 37 · see citing works

Noninvasive 3D MR microscopy as a tool in pharmacological research: Application to a model of rheumatoid arthritis

Beckmann, N., Bruttel, K., Mir, A. K., et al. (1995) · Magnetic Resonance Imaging · doi:10.1016/0730-725x(95)00050-q · Cited by 22 · see citing works

Large-scale brain networks and psychopathology: a unifying triple network model

Menon, V. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.08.003 · Cited by 4,168 · see citing works

Reconsidering anhedonia in depression: Lessons from translational neuroscience

Treadway, M. T., & Zald, D. H. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.06.006 · Cited by 1,579 · see citing works

Frontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response

Pizzagalli, D. A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.166 · Cited by 945 · see citing works

The neurobiology of psychedelic drugs: implications for the treatment of mood disorders

Vollenweider, F. X., & Kometer, M. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2884 · Cited by 723 · see citing works

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?

Steiner, J., Walter, M., Gos, T., Guillemin, G. J., Bernstein, H.-G., Sarnyai, Z., Mawrin, C., Brisch, R., Bielau, H., zu Schwabedissen, L., et al. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-94 · Cited by 568 · see citing works

Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine

Lener, M. S., Niciu, M. J., Ballard, E. D., Park, M., Park, L. T., Nugent, A. C., & Zarate, C. A. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.05.005 · Cited by 468 · see citing works

Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies

Moriguchi, S., Takamiya, A., Noda, Y., Horita, N., Wada, M., Tsugawa, S., Plitman, E., Sano, Y., Tarumi, R., ElSalhy, M., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0252-9 · Cited by 357 · see citing works

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

Beumer, W., Gibney, S. M., Drexhage, R. C., Pont-Lezica, L., Doorduin, J., Klein, H. C., Steiner, J., Connor, T. J., Harkin, A., Versnel, M. A., et al. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0212100 · Cited by 347 · see citing works

Ketamine Decreases Resting State Functional Network Connectivity in Healthy Subjects: Implications for Antidepressant Drug Action

Scheidegger, M., Walter, M., Lehmann, M., Metzger, C., Grimm, S., Boeker, H., Boesiger, P., Henning, A., & Seifritz, E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044799 · Cited by 282 · see citing works

State and training effects of mindfulness meditation on brain networks reflect neuronal mechanisms of its antidepressant effect

Yang, C.-C., Barrós-Loscertales, A., Pinazo, D., Ventura-Campos, N., Borchardt, V., Bustamante, J.-C., Rodríguez-Pujadas, A., Fuentes-Claramonte, P., Balaguer, R., Ávila, C., et al. (2016) · Neural Plasticity · doi:10.1155/2016/9504642 · Cited by 284 · see citing works

Discovering imaging endophenotypes for major depression

Hasler, G., & Northoff, G. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.23 · Cited by 274 · see citing works

Glutamatergic and resting state functional connectivity correlates of severity in major depression - the role of pregenual anterior cingulate cortex and anterior insula

Horn (2010) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2010.00033 · Cited by 276 · see citing works

Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression

Lally, N., Nugent, A. C., Luckenbaugh, D. A., Ameli, R., Roiser, J. P., & Zarate, C. A. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.105 · Cited by 271 · see citing works

Biomarkers in bipolar disorder: a positional paper from the international society for bipolar disorders biomarkers task force.

Frey, B. N., Andreazza, A. C., Houenou, J., Jamain, S., Goldstein, B. I., Frye, M. A., Leboyer, M., Berk, M., Malhi, G. S., Lopez-Jaramillo, C., et al. (2013) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867413478217 · Cited by 234 · see citing works

Striatum-Based Circuitry of Adolescent Depression and Anhedonia

Gabbay, V., Ely, B. A., Li, Q., Bangaru, S. D., Panzer, A. M., Alonso, C. M., Castellanos, F. X., & Milham, M. P. (2013) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2013.04.003 · Cited by 222 · see citing works

Resting state networks in major depressive disorder

Dutta, A., McKie, S., & Deakin, J. F. W. (2014) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2014.10.003 · Cited by 218 · see citing works

The ‘resting-state hypothesis’ of major depressive disorder—A translational subcortical–cortical framework for a system disorder

Northoff, G., Wiebking, C., Feinberg, T., & Panksepp, J. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.12.007 · Cited by 222 · see citing works

Neural correlates of change in major depressive disorder anhedonia following open-label ketamine

Lally, N., Nugent, A. C., Luckenbaugh, D. A., Niciu, M. J., Roiser, J. P., & Zarate, C. A. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881114568041 · Cited by 224 · see citing works

Anterior Cingulate Cortexγ-Aminobutyric Acid in Depressed Adolescents: Relationship to Anhedonia

Gabbay, V. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.131 · Cited by 201 · see citing works

Pretreatment Rostral Anterior Cingulate Cortex Theta Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial

Pizzagalli, D. A., Webb, C. A., Dillon, D. G., Tenke, C. E., Kayser, J., Goer, F., Fava, M., McGrath, P., Weissman, M., Parsey, R., et al. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.0252 · Cited by 189 · see citing works

The role of depressive subtypes within the neuroinflammation hypothesis of major depressive disorder

Woelfer, M., Kasties, V., Kahlfuss, S., & Walter, M. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2018.03.034 · Cited by 171 · see citing works

The association of interoceptive awareness and alexithymia with neurotransmitter concentrations in insula and anterior cingulate

Ernst, J., Böker, H., Hättenschwiler, J., Schüpbach, D., Northoff, G., Seifritz, E., & Grimm, S. (2014) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nst058 · Cited by 161 · see citing works

Mapping anhedonia-specific dysfunction in a transdiagnostic approach: an ALE meta-analysis

Zhang, B., Lin, P., Shi, H., Öngür, D., Auerbach, R. P., Wang, X., Yao, S., & Wang, X. (2016) · Brain Imaging and Behavior · doi:10.1007/s11682-015-9457-6 · Cited by 152 · see citing works

Indirect evidence of selective glial involvement in glutamate-based mechanisms of mood regulation in depression: Meta-analysis of absolute prefrontal neuro-metabolic concentrations

Arnone, D., Mumuni, A. N., Jauhar, S., Condon, B., & Cavanagh, J. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.04.016 · Cited by 150 · see citing works

Is subcortical–cortical midline activity in depression mediated by glutamate and GABA? A cross-species translational approach

Alcaro, A., Panksepp, J., Witczak, J., Hayes, D. J., & Northoff, G. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.11.023 · Cited by 144 · see citing works

Prediction on treatment improvement in depression with resting state connectivity: A coordinate-based meta-analysis

Long, Z., Du, L., Zhao, J., Wu, S., Zheng, Q., & Lei, X. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.06.072 · Cited by 136 · see citing works

Brain imaging of the self-conceptual, anatomical and methodological issues

Northoff, G., Qin, P., & Feinberg, T. E. (2011) · Consciousness and Cognition · doi:10.1016/j.concog.2010.09.011 · Cited by 135 · see citing works

Ventromedial prefrontal spectroscopic abnormalities over the course of depression: A comparison among first episode, remitted recurrent and chronic patients

Portella, M. J., de Diego-Adeliño, J., Gómez-Ansón, B., Morgan-Ferrando, R., Vives, Y., Puigdemont, D., Pérez-Egea, R., Ruscalleda, J., Álvarez, E., & Pérez, V. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.08.010 · Cited by 127 · see citing works

Comparing the actions of lanicemine and ketamine in depression: key role of the anterior cingulate

Downey, D., Dutta, A., McKie, S., Dawson, G. R., Dourish, C. T., Craig, K., Smith, M. A., McCarthy, D. J., Harmer, C. J., Goodwin, G. M., et al. (2016) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2016.03.006 · Cited by 116 · see citing works

High field FMRI reveals thalamocortical integration of segregated cognitive and emotional processing in mediodorsal and intralaminar thalamic nuclei

Metzger, C. D. (2010) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2010.00138 · Cited by 114 · see citing works

Magnetic resonance imaging and spectroscopy reveal differential hippocampal changes in anhedonic and resilient subtypes of the chronic mild stress rat model

Delgado y Palacios, R., Campo, A., Henningsen, K., Verhoye, M., Poot, D., Dijkstra, J., Van Audekerke, J., Benveniste, H., Sijbers, J., Wiborg, O., et al. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.05.014 · Cited by 113 · see citing works

Mood-congruent amygdala responses to subliminally presented facial expressions in major depression: associations with anhedonia

Stuhrmann, A., Dohm, K., Kugel, H., Zwanzger, P., Redlich, R., Grotegerd, D., Rauch, A. V., Arolt, V., Heindel, W., Suslow, T., et al. (2013) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.120060 · Cited by 112 · see citing works

Neurochemistry of major depression: a study using magnetic resonance spectroscopy

Godlewska, B. R., Near, J., & Cowen, P. J. (2015) · Psychopharmacology · doi:10.1007/s00213-014-3687-y · Cited by 97 · see citing works

Glutamine deficiency in the prefrontal cortex increases depressive-like behaviours in male mice

Lee, Y., Son, H., Kim, G., Kim, S., Lee, D. H., Roh, G. S., Kang, S. S., Cho, G. J., Choi, W. S., & Kim, H. J. (2013) · Journal of Psychiatry & Neuroscience · doi:10.1503/jpn.120024 · Cited by 94 · see citing works

Glutamate concentration in the medial prefrontal cortex predicts resting-state cortical-subcortical functional connectivity in humans

Duncan, N. W., Wiebking, C., Tiret, B., Marjańska, M., Hayes, D. J., Lyttleton, O., Doyon, J., & Northoff, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060312 · Cited by 95 · see citing works

Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients

Zhao, J., Bao, A.-M., Qi, X.-R., Kamphuis, W., Luchetti, S., Lou, J.-S., & Swaab, D. F. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.01.013 · Cited by 70 · see citing works

Prefrontal cortical GABA abnormalities are associated with reduced hippocampal volume in major depressive disorder

Abdallah, C. G., Jackowski, A., Sato, J. R., Mao, X., Kang, G., Cheema, R., Coplan, J. D., Mathew, S. J., & Shungu, D. C. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.04.025 · Cited by 67 · see citing works

Blunted neural response to anticipation, effort and consummation of reward and aversion in adolescents with depression symptomatology

Rzepa, E., Fisk, J., & McCabe, C. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881116681416 · Cited by 68 · see citing works

Linking atypical depression and insulin resistance-related disorders via low-grade chronic inflammation: Integrating the phenotypic, molecular and neuroanatomical dimensions

Sen, Z. D., Danyeli, L. V., Woelfer, M., Lamers, F., Wagner, G., Sobanski, T., & Walter, M. (2021) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.12.020 · Cited by 65 · see citing works

Differential effects of rumination and distraction on ketamine induced modulation of resting state functional connectivity and reactivity of regions within the default-mode network

Lehmann, M., Seifritz, E., Henning, A., Walter, M., Böker, H., Scheidegger, M., & Grimm, S. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw034 · Cited by 57 · see citing works

Distinct neurobiological signatures of brain connectivity in depression subtypes during natural viewing of emotionally salient films

Guo, C. C., Hyett, M. P., Nguyen, V. T., Parker, G. B., & Breakspear, M. J. (2016) · Psychological Medicine · doi:10.1017/s0033291716000179 · Cited by 45 · see citing works

Altered functional connectivity between medial prefrontal cortex and the inferior brainstem in major depression during appraisal of subjective emotional responses: a preliminary study

Smith, R., Allen, J. J. B., Thayer, J. F., & Lane, R. D. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2015.03.007 · Cited by 49 · see citing works

Increase in glutamate/glutamine concentration in the medial prefrontal cortex during mental imagery: A combined functional mrs and fMRI study: Glx Increases During Mental Imagery

Huang, Z., Davis Iv, H. H., Yue, Q., Wiebking, C., Duncan, N. W., Zhang, J., Wagner, N.-F., Wolff, A., & Northoff, G. (2015) · Human Brain Mapping · doi:10.1002/hbm.22841 · Cited by 43 · see citing works

Self-referential processing influences functional activation during cognitive control: An fMRI study

Wagner, G., Koch, K., Schachtzabel, C., Peikert, G., Schultz, C. C., Reichenbach, J. R., Sauer, H., & Schlösser, R. G. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nss074 · Cited by 47 · see citing works

Beyond NMDA Receptors: A Narrative Review of Ketamine’s Rapid and Multifaceted Mechanisms in Depression Treatment

Antos, Z., Żukow, X., Bursztynowicz, L., & Jakubów, P. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413658 · Cited by 21 · see citing works

Persistent Ventral Anterior Cingulate Cortex and Resolved Amygdala Hyper-responses to Negative Outcomes After Depression Remission: A Combined Cross-sectional and Longitudinal Study

Zhang, X., Wang, X., Dong, D., Sun, X., Zhong, X., Xiong, G., Cheng, C., Lei, H., Chai, Y., Yu, M., et al. (2023) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.09.003 · Cited by 11 · see citing works

Dissecting the Pathophysiological Circuit Substrates of Reward and Anhedonia Subdomains

Trébaul, L., Ho, V. M., Ellard, K. K., Barbour, T. A., & Camprodon, J. A. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.02.711

Measuring behavior in mice with chronic stress depression paradigm

Strekalova, T., & Steinbusch, H. W. M. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.12.014 · Cited by 207 · see citing works

Relations Between Subcortical Volumes, Anhedonia Severity, and Reward-Oriented Behaviors in an Anhedonic Transdiagnostic Sample

Gibson, K., Cernasov, P., Walsh, E. C., et al. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.02.692

668 Glutamatergic Activation of Anterior Cingulate Cortex (ACC) Mediates the Affective Component of Visceral Pain: Acquisition Versus Expression

Wu, X., Liu, H., Li, Y., et al. (2010) · Gastroenterology · doi:10.1016/s0016-5085(10)60413-1

1H-MRS of the anterior cingulate cortex in obsessive-compulsive disorder: glutamatergic abnormalities in ACC – controlled study

Nosková, E., Fajnerová, I., Pajuelo, D., et al. (2022) · Neuroscience Applied · doi:10.1016/j.nsa.2022.100681