Dissociative disorders in DSM-5
Open accessAbstract
BACKGROUND: We present recommendations for revision of the diagnostic criteria for the Dissociative Disorders (DDs) for DSM-5. The periodic revision of the DSM provides an opportunity to revisit the assumptions underlying specific diagnoses and the empirical support, or lack of it, for the defining diagnostic criteria. METHODS: This paper reviews clinical, phenomenological, epidemiological, cultural, and neurobiological data related to the DDs in order to generate an up-to-date, evidence-based set of DD diagnoses and diagnostic criteria for DSM-5. First, we review the definitions of dissociation and the differences between the definitions of dissociation and conceptualization of DDs in the DSM-IV-TR and the ICD-10, respectively. Also, we review more general conceptual issues in defining dissociation and dissociative disorders. Based on this review, we propose a revised definition of dissociation for DSM-5 and discuss the implications of this definition for understanding dissociative symptoms and disorders. RESULTS: We make the following recommendations for DSM-5: 1. Depersonalization Disorder (DPD) should derealization symptoms as well. 2. Dissociative Fugue should become a subtype of Dissociative Amnesia (DA). 3. The diagnostic criteria for DID should be changed to emphasize the disruptive nature of the dissociation and amnesia for everyday as well as traumatic events. The experience of possession should be included in the definition of identity disruption. 4. Should Dissociative Trance Disorder should be included in the Unspecified Dissociative Disorder (UDD) category. CONCLUSIONS: There is a growing body of evidence linking the dissociative disorders to a trauma history, and to specific neural mechanisms.
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DID is both a successful survival strategy in the context of childhood maltreatment and a cause of significant distress and impairment in other contexts.
“In this way, DID represents a paradoxical condition: it is both a successful survival strategy in the context of childhood maltreatment as well as a cause of significant distress and impairment in other contexts [14,19,36,42].”
From Treatment of dissociative identity disorder: leveraging neurobiology to optimize success (2024) · cites this paper as [42]
In “Dissociative Symptoms and the Subjective Experience of Dissociation” (page not specified), the paper hypothesizes that dissociation may help children cope with traumatizing circumstances; it does not establish DID as a successful survival strategy. That section describes distressing DID symptoms, and the proposed DID criteria specify clinically significant distress and impairment. (LLM, conf=0.86)
Experimental — accuracy not yet measuredPeople with DID experience amnesia, or gaps in memory, for important personal information, aspects of traumatic experiences, and day-to-day events.
“People with DID also experience amnesia, or gaps in their memory, for important personal information, aspects of traumatic experiences, and day-to-day events [1,43].”
From Treatment of dissociative identity disorder: leveraging neurobiology to optimize success (2024) · cites this paper as [43]
PTSD + DS is highly associated with early life traumatization, where dissociation acts as an adaptive response to inescapable threat.
“PTSD + DS is highly associated with early life traumatization, where dissociation acts as an adaptive response to inescapable threat ( Nijenhuis et al., 1998a ; Chu et al., 1999 ; Spiegel et al., 2011 ; Wolf et al., 2012a ; Stein et al., 2013 ; Lowenstein, 2018 ).”
From The brain-body disconnect: A somatic sensory basis for trauma-related disorders (2022) · cites this paper as Spiegel et al., 2011
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“PTSD + DS is highly associated with early life traumatization, where dissociation acts as an adaptive response to inescapable threat (Nijenhuis et al., 1998a; Chu et al., 1999; Spiegel et al., 2011; Wolf et al., 2012a; Stein et al., 2013; Lowenstein, 2018).”
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The relationship between dissociation and voices: A systematic literature review and meta-analysis
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Lanius, R. A. (2015) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v6.27905 · Cited by 127 · see citing works
Krause-Utz, A., Frost, R., Winter, D., & Elzinga, B. M. (2017) · Current Psychiatry Reports · doi:10.1007/s11920-017-0757-y · Cited by 116 · see citing works
“Dissociation in Borderline Personality Disorder (BPD) Transient stress-related dissociation is a hallmark of BPD [6, 11•, 107]. It has been defined as one of the nine diagnostic criteria for the disorder in DSM-IV [108]. In DSM-V [5], “dissociative states under stress” are still listed among other BPD key features suc…”
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Self-citationBrand, B. L., Schielke, H. J., Putnam, K. T., Putnam, F. W., Loewenstein, R. J., Myrick, A., Jepsen, E. K. K., Langeland, W., Steele, K., Classen, C. C., et al. (2019) · Journal of Traumatic Stress · doi:10.1002/jts.22370 · Cited by 87 · see citing works
Self-citationDispelling Myths About Dissociative Identity Disorder Treatment: An Empirically Based Approach
Brand, B. L., Loewenstein, R. J., & Spiegel, D. (2014) · Psychiatry: Interpersonal and Biological Processes · doi:10.1521/psyc.2014.77.2.169 · Cited by 85 · see citing works
Self-citationBrain circuits implicated in psychogenic paralysis in conversion disorders and hypnosis
Vuilleumier, P. (2014) · Neurophysiologie Clinique/Clinical Neurophysiology · doi:10.1016/j.neucli.2014.01.003 · Cited by 82 · see citing works
Inter-identity autobiographical amnesia in patients with dissociative identity disorder
Huntjens, R. J. C., Verschuere, B., & McNally, R. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040580 · Cited by 76 · see citing works
Beutler, S., Mertens, Y. L., Ladner, L., Schellong, J., Croy, I., & Daniels, J. K. (2022) · European Journal of Psychotraumatology · doi:10.1080/20008066.2022.2132599 · Cited by 64 · see citing works
Persistent Dissociation and Its Neural Correlates in Predicting Outcomes After Trauma Exposure
Lebois, L. A. M., Harnett, N. G., van Rooij, S. J. H., Ely, T. D., Jovanovic, T., Bruce, S. E., House, S. L., Ravichandran, C., Dumornay, N. M., Finegold, K. E., et al. (2022) · American Journal of Psychiatry · doi:10.1176/appi.ajp.21090911 · Cited by 60 · see citing works
Krause-Utz, A., Winter, D., Schriner, F., Chiu, C.-D., Lis, S., Spinhoven, P., Bohus, M., Schmahl, C., & Elzinga, B. M. (2018) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-017-0806-x · Cited by 57 · see citing works
Pharmacotherapy for dissociative disorders: A systematic review
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Radulovic, J., Lee, R., & Ortony, A. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00259 · Cited by 26 · see citing works
Attachment Representations and Autonomic Regulation in Maltreating and Nonmaltreating Mothers
Reijman, S., Alink, L. R. A., Compier-De Block, L. H. C. G., Werner, C. D., Maras, A., Rijnberk, C., Van Ijzendoorn, M. H., & Bakermans-Kranenburg, M. J. (2017) · Development and Psychopathology · doi:10.1017/s0954579416001036 · Cited by 26 · see citing works
Dissociation by network integration
Menon, V. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20121728 · Cited by 19 · see citing works
Firebug! Dissociative Identity Disorder? Malingering? Or …? An Intensive Case Study of an Arsonist
Loewenstein, R. J. (2020) · Psychological Injury and Law · doi:10.1007/s12207-020-09377-8 · Cited by 16 · see citing works
Self-citationTreatment of dissociative identity disorder: leveraging neurobiology to optimize success
Purcell, J. B., Brand, B., Browne, H. A., Chefetz, R. A., Shanahan, M., Bair, Z. A., Baranowski, K. A., Davis, V., Mangones, P., Modell, R. L., et al. (2024) · Expert review of neurotherapeutics · doi:10.1080/14737175.2024.2316153 · Cited by 17 · see citing works
“People with DID also experience amnesia or gaps in their memory, for important personal information, aspects of traumatic experiences, and day-to-day events [1,42].”
Background
- Authors
- Spiegel, D., Loewenstein, R. J., Lewis-Fernández, R., Sar, V., Simeon, D., Vermetten, E., Cardeña, E., & Dell, P. F.
- Affiliations
- Stanford University (US)
- Sheppard Pratt Health System (US)
- Albert Einstein College of Medicine (US)
- University Medical Center Utrecht (NL)
- Lund University (SE)
- Corresponding author
- Spiegel, David
- Venue
- Depression and Anxiety
- Publisher
- Wiley
- Published
- 2011-09
- Volume
- 28
- Issue
- 9
- Pages
- 824-852
- ISSN
- 1091-4269 (ISSN-L)
- OpenAlex
- W2095692557
- Cited by
- 330
- References
- 369
- Citations by year
- 2026: 19 · 2025: 16 · 2024: 20 · 2023: 24 · 2022: 23 · 2021: 14 · 2020: 15 · 2019: 14 · 2018: 18 · 2017: 25 · 2016: 24 · 2015: 24 · 2014: 46 · 2013: 28 · 2012: 16
- FWCI
- 3.90
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Depression and Anxiety (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Keywords
- dissociative disorders, DSM-5, diagnostic criteria, dissociation, depersonalization disorder, derealization, dissociative fugue, dissociative amnesia, dissociative identity disorder, identity disruption, possession, trauma history
- MeSH terms
- Conversion Disorder, Depersonalization, Diagnosis, Differential, Dissociative Disorders, Humans, Life Change Events, Psychotic Disorders, Risk Factors, Comorbidity, International Classification of Diseases, Diagnostic and Statistical Manual of Mental Disorders, Evidence-Based Practice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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