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Cited by 481

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Altered small‐world brain functional networks in children with attention‐deficit/hyperactivity disorder

Open access
Wang, Liang, Zhu, Chaozhe, He, Yong, Zang, Yufeng, Cao, QingJiu, Zhang, Han, Zhong, Qiuhai, Wang, Yufeng·2009·Human Brain Mapping
DOI 10.1002/hbm.20530
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Abstract

In this study, we investigated the changes in topological architectures of brain functional networks in attention‐deficit/hyperactivity disorder (ADHD). Functional magnetic resonance images (fMRI) were obtained from 19 children with ADHD and 20 healthy controls during resting state. Brain functional networks were constructed by thresholding the correlation matrix between 90 cortical and subcortical regions and further analyzed by applying graph theoretical approaches. Experimental results showed that, although brain networks of both groups exhibited economical small‐world topology, altered functional networks were demonstrated in the brain of ADHD when compared with the normal controls. In particular, increased local efficiencies combined with a decreasing tendency in global efficiencies found in ADHD suggested a disorder‐related shift of the topology toward regular networks. Additionally, significant alterations in nodal efficiency were also found in ADHD, involving prefrontal, temporal, and occipital cortex regions, which were compatible with previous ADHD studies. The present study provided the first evidence for brain dysfunction in ADHD from the viewpoint of global organization of brain functional networks by using resting‐state fMRI. Hum Brain Mapp, 2009. © 2008 Wiley‐Liss, Inc.

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Cited by

Metadata

Authors
Wang, L., Zhu, C., He, Y., Zang, Y., Cao, Q., Zhang, H., Zhong, Q., & Wang, Y.
Venue
Human Brain Mapping
Publisher
Wiley
Published
2009-01-19
Volume
30
Issue
2
Pages
638-649
ISSN
  • 1065-9471 (ISSN-L)
  • 1097-0193
DOI
10.1002/hbm.20530
OpenAlex
W2067219344
Cited by
481
References
21
FWCI
10.88
Type
journal article
Language
en
Open access
bronze
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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