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Leptin signaling and leptin resistance
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As leptin functions via binding of the leptin receptor, changes in its expression and splicing can reduce metabolism at a given concentration of leptin.
“As leptin functions via binding of the leptin receptor, changes in its expression and splicing can reduce metabolism at a given concentration of leptin.”
From BACE1: More than just a β‐secretase (2022) · cites this paper as [104]
Generally, a greater fat deposit in adipocytes results in greater leptin release, and therefore, theoretically, increased lipids should equate to decreased hunger.
“Generally, a greater fat deposit in adipocytes results in greater leptin release, and therefore, theoretically, increased lipids should equate to decreased hunger.”
From BACE1: More than just a β‐secretase (2022) · cites this paper as [104]
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BackgroundIncreased Hypothalamic Protein Tyrosine Phosphatase 1B Contributes to Leptin Resistance with Age
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Metadata
- Authors
- Zhou, Y., & Rui, L.
- Venue
- Frontiers of Medicine
- Published
- 2013-04-12
- Volume
- 7
- Issue
- 2
- Pages
- 207-222
- ISSN
- 2095-0217
- 2095-0225
- PMC
- PMC4069066
- Cited by
- 358
- References
- 43
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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