El escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis

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The spectrum of disease in chronic traumatic encephalopathy

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How common are the "common" neurologic disorders?

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Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

Majounie, E., Renton, A. E., Mok, K., Dopper, E. G., Waite, A., Rollinson, S., Chiò, A., Restagno, G., Nicolaou, N., Simon-Sanchez, J., et al. (2012) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70043-1 · Cited by 1,210

Prognostic factors in ALS: A critical review

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Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria

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Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature

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The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK

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Incidence of amyotrophic lateral sclerosis in Europe

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The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

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<emph type="ital">SQSTM1</emph> Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

Fecto, F. (2011) · Archives of Neurology · doi:10.1001/archneurol.2011.250 · Cited by 650

Frontotemporal dementia

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Amyotrophic lateral sclerosis: moving towards a new classification system

Al-Chalabi, A., Hardiman, O., Kiernan, M. C., Chiò, A., Rix-Brooks, B., & van den Berg, L. H. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(16)30199-5 · Cited by 390

The epidemiology of amyotrophic lateral sclerosis

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Circulating endotoxin and systemic immune activation in sporadic amyotrophic lateral sclerosis (sALS)

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Glutamate Transporters in Neurologic Disease

Maragakis, N. J., & Rothstein, J. D. (2001) · Archives of Neurology · doi:10.1001/archneur.58.3.365 · Cited by 324

A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis

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Incidence and prevalence of ALS in Ireland, 1995–1997: A population-based study

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Head Injury and Amyotrophic Lateral Sclerosis

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Quality of life in ALS depends on factors other than strength and physical function

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Occurrence of amyotrophic lateral sclerosis among Gulf War veterans

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TREM2 Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis

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Ethnic variation in the incidence of ALS: A systematic review

Cronin, S., Hardiman, O., & Traynor, B. J. (2007) · Neurology · doi:10.1212/01.wnl.0000258551.96893.6f · Cited by 255

ALSFRS-R score and its ratio: A useful predictor for ALS-progression

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Sexual differences in onset of disease and response to exercise in a transgenic model of ALS

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Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer’s disease.

Lorenzl, S. (2003) · Neurochemistry International · doi:10.1016/s0197-0186(03)00004-4 · Cited by 243

TDP-43 depletion in microglia promotes amyloid clearance but also induces synapse loss

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Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population‐based study

Alonso, A., Logroscino, G., Jick, S. S., & Hernán, M. A. (2009) · European Journal of Neurology · doi:10.1111/j.1468-1331.2009.02586.x · Cited by 229

Excess incidence of ALS in young Gulf War veterans

Haley, R. W. (2003) · Neurology · doi:10.1212/wnl.61.6.750 · Cited by 227

Untitled work

Ince (1998) · doi:10.1046/j.1365-2990.1998.00108.x · Cited by 224

Study of 962 patients indicates progressive muscular atrophy is a form of ALS

Kim, W. K., Liu, X., Sandner, J., Pasmantier, M., Andrews, J., Rowland, L. P., & Mitsumoto, H. (2009) · Neurology · doi:10.1212/wnl.0b013e3181c1dea3 · Cited by 217

Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004

O'Toole, O., Traynor, B. J., Brennan, P., Sheehan, C., Frost, E., Corr, B., & Hardiman, O. (2008) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2007.117788 · Cited by 197

Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies

Geser, F., Lee, V. M.-Y., & Trojanowski, J. Q. (2010) · Neuropathology · doi:10.1111/j.1440-1789.2009.01091.x · Cited by 195

Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Aggarwal, S. P., Zinman, L., Simpson, E., McKinley, J., Jackson, K. E., Pinto, H., Kaufman, P., Conwit, R. A., Schoenfeld, D., Shefner, J., et al. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70068-5 · Cited by 195

Time to diagnosis and factors affecting diagnostic delay in amyotrophic lateral sclerosis

Richards, D., Morren, J. A., & Pioro, E. P. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117054 · Cited by 185

Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72

Mann, D. M., Rollinson, S., Robinson, A., Bennion Callister, J., Thompson, J. C., Snowden, J. S., Gendron, T., Petrucelli, L., Masuda-Suzukake, M., Hasegawa, M., et al. (2013) · Acta Neuropathologica Communications · doi:10.1186/2051-5960-1-68 · Cited by 182

The Complex Molecular Biology of Amyotrophic Lateral Sclerosis (ALS)

Redler, R. L., & Dokholyan, N. V. (2012) · Progress in Molecular Biology and Translational Science · doi:10.1016/b978-0-12-385883-2.00002-3 · Cited by 172

Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NO(x) content in the CSF. A different marker profile in four neurodegenerative diseases

Boll, M.-C., Alcaraz-Zubeldia, M., Montes, S., & Rios, C. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9610-3 · Cited by 173

Patients' assessment of quality of life instruments: a randomised study of SIP, SF-36 and SEIQoL-DW in patients with amyotrophic lateral sclerosis

Neudert, C., Wasner, M., & Borasio, G. D. (2001) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(01)00612-8 · Cited by 157

Tolerance of high‐dose (3,000 mg/day) coenzyme Q10 in ALS

Ferrante, K. L., Shefner, J., Zhang, H., Betensky, R., O'Brien, M., Yu, H., Fantasia, M., Taft, J., Beal, M. F., Traynor, B., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000187070.35365.d7 · Cited by 154

Analysis of survival and prognostic factors in amyotrophic lateral sclerosis: a population based study

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Genetic epidemiology of amyotrophic lateral sclerosis

Majoor‐Krakauer, D., Willems, P., & Hofman, A. (2003) · Clinical Genetics · doi:10.1046/j.0009-9163.2002.00001.x · Cited by 147

Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: a preliminary study

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ALS and other motor neuron diseases

Tiryaki, E., & Horak, H. A. (2014) · Continuum · doi:10.1212/01.con.0000455886.14298.a4 · Cited by 143

Physical activity and the association with sporadic ALS

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Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons.

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Ceruloplasmin oxidation, a feature of Parkinson's disease CSF, inhibits ferroxidase activity and promotes cellular iron retention

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Predictors of psychological distress in carers of people with amyotrophic lateral sclerosis: a longitudinal study

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Association of ALS with head injury, cigarette smoking and APOE genotypes

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Does therapeutic writing help people with long-term conditions? Systematic review, realist synthesis and economic considerations

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TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia

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What causes amyotrophic lateral sclerosis?

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Physical activity and amyotrophic lateral sclerosis: A European population‐based case–control study

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Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture

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The psychological impact of MND on patients and carers

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Antioxidant treatment for amyotrophic lateral sclerosis or motor neuron disease

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Mechanical Insufflation-Exsufflation vs. Tracheal Suctioning via Tracheostomy Tubes for Patients with Amyotrophic Lateral Sclerosis: A Pilot Study

Sancho, J., Servera, E., Vergara, P., & Marín, J. (2003) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/01.phm.0000087456.28979.2e · Cited by 93

Apolipoprotein E genotyping in sporadic amyotrophic lateral sclerosis: evidence for a major influence on the clinical presentation and prognosis

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Discriminative and prognostic potential of cerebrospinal fluid phosphoTau/tau ratio and neurofilaments for frontotemporal dementia subtypes

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TBK1 mutation frequencies in French frontotemporal dementia and amyotrophic lateral sclerosis cohorts

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Sports and trauma in amyotrophic lateral sclerosis revisited

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Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum

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Health-related quality of life in ALS, myasthenia gravis and facioscapulohumeral muscular dystrophy

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Cause of death and clinical grading criteria in a cohort of amyotrophic lateral sclerosis cases undergoing autopsy from the Scottish Motor Neurone Disease Register

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Neurodegeneration in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9orf72 is linked to TDP‐43 pathology and not associated with aggregated forms of dipeptide repeat proteins

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Trauma and amyotrophic lateral sclerosis: a case–control study from a population‐based registry

Pupillo, E., Messina, P., Logroscino, G., Zoccolella, S., Chiò, A., Calvo, A., Corbo, M., Lunetta, C., Micheli, A., Millul, A., et al. (2012) · European Journal of Neurology · doi:10.1111/j.1468-1331.2012.03723.x · Cited by 78

Clinical use of diffusion-tensor imaging for diseases causing neuronal and axonal damage.

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A systematic review of behavioural changes in motor neuron disease

Raaphorst, J., Beeldman, E., De Visser, M., De Haan, R. J., & Schmand, B. (2012) · Amyotrophic Lateral Sclerosis · doi:10.3109/17482968.2012.656652 · Cited by 75

IL-15 Is Elevated in Cerebrospinal Fluid of Patients With Alzheimer’s Disease and Frontotemporal Dementia

Rentzos, M., Zoga, M., Paraskevas, G. P., Kapaki, E., Rombos, A., Nikolaou, C., Tsoutsou, A., & Vassilopoulos, D. (2006) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988706286226 · Cited by 65

Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72

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Progressive Muscular Atrophy

Liewluck, T., & Saperstein, D. S. (2015) · Neurologic Clinics · doi:10.1016/j.ncl.2015.07.005 · Cited by 65

Incidence and Geographical Variation of Amyotrophic Lateral Sclerosis (ALS) in Southern Germany – Completeness of the ALS Registry Swabia

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Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study

Schneider, R., McKeever, P., Kim, T., Graff, C., van Swieten, J. C., Karydas, A., Boxer, A., Rosen, H., Miller, B. L., Laforce Jr, R., et al. (2018) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2017-317492 · Cited by 62

Coping strategies as related to medical and demographic data in amyotrophic lateral sclerosis

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Euthanasia and physician-assisted suicide in amyotrophic lateral sclerosis: a prospective study

Maessen, M., Veldink, J. H., Onwuteaka-Philipsen, B. D., Hendricks, H. T., Schelhaas, H. J., Grupstra, H. F., van der Wal, G., & van den Berg, L. H. (2014) · Journal of Neurology · doi:10.1007/s00415-014-7424-6 · Cited by 61

Environmental and Occupational Risk Factors for Amyotrophic Lateral Sclerosis: A Case-Control Study

Malek, A. M., Barchowsky, A., Bowser, R., Heiman-Patterson, T., Lacomis, D., Rana, S., Youk, A., Stickler, D., Lackland, D. T., & Talbott, E. O. (2014) · Neurodegenerative Diseases · doi:10.1159/000355344 · Cited by 60

Factors supporting quality of life over time for individuals with amyotrophic lateral sclerosis: the role of positive self-perception and religiosity

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Noninvasive 13C-Octanoic Acid Breath Test Shows Delayed Gastric Emptying in Patients with Amyotrophic Lateral Sclerosis

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The role of soluble intercellular adhesion molecules in neurodegenerative disorders

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Do pain, anxiety and depression influence quality of life for people with amyotrophic lateral sclerosis/motor neuron disease? A national study reconciling previous conflicting literature

the TONiC study group, Edge, R., Mills, R., Tennant, A., Diggle, P. J., & Young, C. A. (2020) · Journal of Neurology · doi:10.1007/s00415-019-09615-3 · Cited by 47

Association of Lead Exposure with Survival in Amyotrophic Lateral Sclerosis

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Head injury does not alter disease progression or neuropathologic outcomes in ALS

Fournier, C. N., Gearing, M., Upadhyayula, S. R., Klein, M., & Glass, J. D. (2015) · Neurology · doi:10.1212/wnl.0000000000001522 · Cited by 44

Trauma and amyotrophic lateral sclerosis: a european population-based case-control study from the EURALS consortium

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Factors that facilitate and hinder the manageability of living with amyotrophic lateral sclerosis in both patients and next of kin

Olsson Ozanne, A., Graneheim, U. H., Persson, L., & Strang, S. (2012) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2011.03809.x · Cited by 37

Occasional essay: upper motor neuron syndrome in amyotrophic lateral sclerosis

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The Department of Veterans Affairs Biorepository Brain Bank: A national resource for amyotrophic lateral sclerosis research

Brady, C. B., Trevor, K. T., Stein, T. D., Deykin, E. Y., Perkins, S. D., Averill, J. G., Guilderson, L., Mckee, A. C., Renner, S. W., & Kowall, N. W. (2013) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.3109/21678421.2013.822516 · Cited by 19

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