CoChat
Sign Up
Cited by 162Neuroendocrine regulation and behaviorAnimal Behavior and ReproductionOlfactory and Sensory Function Studies

Cohabitation alters vasopressin innervation and paternal behavior in prairie voles (Microtus ochrogaster)

Bamshad, Maryam, Novak, Melinda A., de Vries, Geert J.·1994·Physiology & Behavior
DOI 10.1016/0031-9384(94)90238-0
Open this paper in CoChat — free account

Abstract

The density of vasopressin-immunoreactive (AVP-ir) fibers in the lateral septum and lateral habenular nucleus is lower in prairie vole fathers--which display paternal behavior under natural conditions-than in sexually naive males. To see if these changes occur before or after the birth of pups, and whether they are related to changes in paternal behavior, we tested paternal responsiveness and measured AVP-ir fiber density in the lateral septum, lateral habenular nucleus, medial preoptic area, and paraventricular nucleus of the thalamus of sexually naive males and females (0P) and breeding pairs that were sacrificed shortly after mating (3P); during early (13P); or late gestation (21P); or after the birth of pups (6PP). Paternal responsiveness was increased in 3P males and reached a plateau in 13P males. AVP-ir fiber density did not change in the medial preoptic area and the paraventricular nucleus of the thalamus. The fiber density in the lateral septum and lateral habenular nucleus was affected differently in males and females. Among males, 3P animals had the lowest fiber density, while 13P and 6PP animals had an intermediate, and 0P and 21P animals the highest fiber density, whereas among females, no differences in fiber density were found. A second experiment showed that the decrease in fiber density in 3P males could be induced by cohabitation with an unfamiliar female but not by an unfamiliar male nor by relocation to a novel cage. The changes in AVP-ir fiber density shortly after mating suggest that these fibers may be involved in paternal responsiveness as well as in various other social behaviors that change after mating.

Integrity signals

Registry

Crossref · 10.1016/0031-9384(94)90238-0

Cites

33 of 33 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • In prairie voles, cohabitation with a female resulted in a decrease in AVP content in the lateral septum, coincident with an increase in paternal responsiveness.

    “Early comparative studies discovered that in prairie voles, cohabitation with a female resulted in a decrease in AVP content in the lateral septum (likely reflecting a release of AVP from neuronal fibers in the region), which was coincident with an increase in paternal responsiveness.”

    From The prairie vole: An emerging model organism for understanding the social brain (2010) · cites this paper as [36]

  • The decrease in AVP content in the lateral septum after cohabitation with a female was not observed in meadow voles.

    “This phenomenon was not observed in meadow voles [36, 37].”

    From The prairie vole: An emerging model organism for understanding the social brain (2010) · cites this paper as [36]

Cites

Flagged first, then by citations

1 of the 34 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Bamshad, M., Novak, M. A., & de Vries, G. J.
Affiliations
University of Massachusetts Amherst (US)
ORCID
Novak, Melinda A.
Venue
Physiology & Behavior
Publisher
Elsevier BV
Published
1994-10
Volume
56
Issue
4
Pages
751-758
ISSN
0031-9384 (ISSN-L)
DOI
10.1016/0031-9384(94)90238-0
OpenAlex
W1991358167
Cited by
162
References
34
Citations by year
2026: 2 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 3 · 2018: 5 · 2017: 7 · 2016: 9 · 2015: 5 · 2014: 8 · 2013: 7 · 2012: 3
FWCI
9.71
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Physiology & Behavior (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (RO1 MH47538)
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
  • Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
Keywords
vasopressin, cohabitation, paternal behavior, Microtus ochrogaster, lateral septum, lateral habenula, social behavior, mating, gestation, sex differences, neuroendocrine regulation
MeSH terms
Amygdala, Animals, Arginine Vasopressin, Brain, Brain Mapping, Arvicolinae, Female, Immunoenzyme Techniques, Male, Nerve Fibers, Neural Pathways, Pair Bond, Paraventricular Hypothalamic Nucleus, Paternal Behavior, Pregnancy, Preoptic Area, Septum Pellucidum, Thalamic Nuclei

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review