The Alzheimer’s disease mitochondrial cascade hypothesis: progress and perspectives

Swerdlow, Russell H., Burns, Jeffrey M., Khan, Shaharyar M.·2014·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
DOI 10.1016/j.bbadis.2013.09.010

Cites (286)

Items 201–275 of 275

  1. Quantitative structural MRI for early detection of Alzheimer's disease
    McEvoy, Linda K, Brewer, James B · 2010 · Expert Review of Neurotherapeutics
  2. Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells
    Gasparini, Laura, Racchi, Marco, Benussi, Luisa, Curti, Daniela, Binetti, Giuliano, Bianchetti, Angelo, Trabucchi, Marco, Govoni, Stefano · 1997 · Neuroscience Letters
  3. Aging and mitochondria
    Maria Nicola Gadaleta, Antonella Cormio, Vito Pesce, Angela Maria Serena Lezza, Palmiro Cantatore · 1998 · Biochimie
  4. Cognition, aging, and disabilities: conceptual issues
    Borson, Soo · 2010 · Physical Medicine and Rehabilitation Clinics of North America
  5. Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes
    Mosconi, Lisa, Berti, Valentina, Swerdlow, Russell H, Pupi, Alberto, Duara, Ranjan, de Leon, Mony · 2010 · Human Genomics
  6. Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology
    Nagy, Zs., Esiri, M. M., LeGris, M., Matthews, P. M. · 1999 · Acta Neuropathologica
  7. A chronic Alzheimer’s model evoked by mitochondrial poison sodium azide for pharmacological investigations
    Tamás Szabados, Csaba Dul, Katalin Majtényi, Judit Hargitai, Zoltán Pénzes, Rudolf Urbanics · 2004 · Behavioural Brain Research
  8. Treating neurodegeneration by modifying mitochondria: potential solutions to a “complex” problem
    Swerdlow, Russell H. · 2007 · Antioxidants & Redox Signaling
  9. No disease in the brain of a 115 year old woman
    den Dunnen, Wilfred F.A., Brouwer, Wiebo H., Bijlard, Eveline, Kamphuis, Jeanine, van Linschoten, Klaas, Eggens-Meijer, Ellie, Holstege, Gert · 2008 · Neurobiology of Aging
  10. Maternal family history is associated with Alzheimer's disease biomarkers
    Honea, Robyn A., for the Alzheimer's Disease Neuroimaging Initiative, Vidoni, Eric D., Swerdlow, Russell H., Burns, Jeffrey M. · 2012 · Journal of Alzheimer s Disease
  11. Association of parental dementia with cognitive and brain MRI measures in middle-aged adults
    Stéphanie Debette, Philip A. Wolf, Alexa Beiser, Rhoda Au, Jayandra Jung Himali, Aleksandra Pikula, Sanford H. Auerbach, Charles S DeCarli, Sudha S. Seshadri · 2009 · Neurology
  12. Cerebrospinal Fluid Biomarkers and Memory Present Distinct Associations along the Continuum from Healthy Subjects to AD Patients
    Lorena Rami, Juan Fortea, Beatríz Bosch, Cristina Solé‐Padullés, Albert Lladó, Álex Iranzo, Raquel Sánchez‐Valle, José Luís Molinuevo · 2011 · Journal of Alzheimer s Disease
  13. Genetic variation in APOE cluster region and Alzheimer's disease risk
    Sebastián Cervantes, Lluı́s Samaranch, Jose Manuel Vidal-Taboada, Isabel Lamet, Maria Jesus Bullido, Ana Frank, Francisco Coria, Albert Lleó, Jordi Clarimón, Elena Lorenzo et al. · 2011 · Neurobiology of Aging
  14. Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects
    De Santi, Susan, de Leon, Mony J., Convit, Antonio, Tarshish, Chaim, Rusinek, Henry, Tsui, Wai Hon, Sinaiko, Elia, Wang, Gene-Jack, Bartlet, Elsa, Volkow, Nora · 1995 · Psychiatric Quarterly
  15. Using genetics to enable studies on the prevention of Alzheimer's disease
    Crenshaw, D G, Gottschalk, W K, Lutz, M W, Grossman, I, Saunders, A M, Burke, J R, Welsh-Bohmer, K A, Brannan, S K, Burns, D K, Roses, A D · 2013 · Clinical Pharmacology & Therapeutics
  16. Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case–control cohort
    Elias-Sonnenschein, Lyzel S., Helisalmi, Seppo, Natunen, Teemu, Hall, Anette, Paajanen, Teemu, Herukka, Sanna-Kaisa, Laitinen, Marjo, Remes, Anne M., Koivisto, Anne M., Mattila, Kari M. et al. · 2013 · PLoS ONE
  17. The application of cerebrospinal fluid biomarkers in early diagnosis of Alzheimer disease
    Blennow, Kaj, Zetterberg, Henrik · 2013 · Medical Clinics of North America
  18. Developmental changes in brain metabolism in sedated rhesus macaques and vervet monkeys revealed by positron emission tomography
    Jacobs, B., Chugani, H. T., Allada, V., Chen, S., Phelps, M. E., Pollack, D. B., Raleigh, M. J. · 1995 · Cerebral Cortex
  19. Longitudinal modeling of cognitive aging and the <i>TOMM40</i> effect
    Caselli, Richard J., Dueck, Amylou C., Huentelman, Matthew J., Lutz, Michael W., Saunders, Ann M., Reiman, Eric M., Roses, Allen D. · 2012 · Alzheimer's &amp; Dementia
  20. Pathogenesis of Alzheimer’s Disease
    Rudy J. Castellani, George L. Perry · 2014 · Springer eBooks
  21. Evidence for parent of origin effect in late-onset Alzheimer disease
    Bassett, Susan Spear, Avramopoulos, Dimitrios, Fallin, Daniele · 2002 · American Journal of Medical Genetics
  22. Alzheimer’s Disease Pathologic Cascades: Who Comes First, What Drives What
    Russell Howard Swerdlow · 2011 · Neurotoxicity Research
  23. <i>TOMM40</i> and <i>APOE</i>: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial
    Roses, Allen D., Lutz, Michael W., Crenshaw, Donna G., Grossman, Iris, Saunders, Ann M., Gottschalk, W. Kirby · 2013 · Alzheimer's &amp; Dementia
  24. Longitudinal plasma amyloid beta as a biomarker of Alzheimer’s disease
    Robert A. Rissman, John Q. Trojanowski, Leslie M. J. Shaw, Paul S. S. Aisen · 2012 · Journal of Neural Transmission
  25. The effects of perturbed energy metabolism on the processing of amyloid precursor protein in PC12 cells
    Webster, M.-T., Pearce, B. R., Bowen, D. M., Francis, P. T. · 1998 · Journal of Neural Transmission
  26. Altered Glucose Metabolism in Fibroblasts from Patients with Alzheimer's Disease
    Neil R. Sims, Janet M. Finegan, John P. Blass · 1985 · New England Journal of Medicine
  27. Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis
    Katja Scheffler, Markus Krohn, Tina Dunkelmann, Jan Stenzel, Bruno Miroux, Saleh Mohamed Ibrahim, Oliver von Bohlen und Halbach, Hans‐Jochen Heinze, Lary C. Walker, Jörg A. Gsponer et al. · 2012 · Acta Neuropathologica
  28. Characterization of the Poly-T Variant in the TOMM40 Gene in Diverse Populations
    Colton L. Linnertz, Ann M. Saunders, Michael William Lutz, Donna G. Crenshaw, Iris Grossman, Daniel K. Burns, Keith E. Whitfield, Michael A. Hauser, Jeanette J. McCarthy, Megan Ulmer Carnes et al. · 2012 · PLoS ONE
  29. Structural brain changes in normal individuals with a maternal history of Alzheimer's
    Berti, Valentina, Mosconi, Lisa, Glodzik, Lidia, Li, Yi, Murray, John, De Santi, Susan, Pupi, Alberto, Tsui, Wai, De Leon, Mony J. · 2011 · Neurobiology of Aging
  30. The Frequency of Point Mutations in Mitochondrial DNA Is Elevated in the Alzheimer's Brain
    Shin-Wen Chang, Dekui Zhang, Hyung D. Chung, Hans Peter Zassenhaus · 2000 · Biochemical and Biophysical Research Communications
  31. Is mitochondrial DNA depletion involved in Alzheimer's disease?
    Rodríguez-Santiago, Benjamín, Casademont, Jordi, Nunes, Virginia · 2001 · European Journal of Human Genetics
  32. Effects of ApoE4 and maternal history of dementia on hippocampal atrophy
    Andrawis, John P., Hwang, Kristy S., Green, Amity E., Kotlerman, Jenny, Elashoff, David, Morra, Jonathan H., Cummings, Jeffrey L., Toga, Arthur W., Thompson, Paul M., Apostolova, Liana G. · 2012 · Neurobiology of Aging
  33. Possible association of mitochondrial transcription factor A (TFAM) genotype with sporadic Alzheimer disease
    Günther, Claudia, Hadeln, Kirsten von, Müller-Thomsen, Tomas, Alberici, Antonella, Binetti, Giuliano, Hock, Christoph, Nitsch, Roger M., Stoppe, Gabriela, Reiss, Jochen, Gal, Andreas et al. · 2004 · Neuroscience Letters
  34. A homopolymer polymorphism in the <i>TOMM40</i> gene contributes to cognitive performance in aging
    Hayden, Kathleen M., McEvoy, Jill M., Linnertz, Colton, Attix, Deborah, Kuchibhatla, Maragatha, Saunders, Ann M., Lutz, Michael W., Welsh‐Bohmer, Kathleen A., Roses, Allen D., Chiba‐Falek, Ornit · 2012 · Alzheimer's &amp; Dementia
  35. TOMM40 rs10524523 polymorphism's role in late-onset Alzheimer's disease and in longevity
    Maruszak, Aleksandra, Pepłońska, Beata, Safranow, Krzysztof, Chodakowska-Żebrowska, Małgorzata, Barcikowska, Maria, Żekanowski, Cezary · 2012 · Journal of Alzheimer s Disease
  36. The levels of cerebrospinal fluid Aβ40 and Aβ42(43) are regulated age-dependently
    Shoji, M., Kanai, M., Matsubara, E., Tomidokoro, Y., Shizuka, M., Ikeda, Y., Ikeda, M., Harigaya, Y., Okamoto, K., Hirai, S. · 2001 · Neurobiology of Aging
  37. Brain Glucose Metabolism in Alzheimer’s Disease
    Russell Howard Swerdlow, David L. Marcus, Jaime Landman, David A. Kooby, William H. Frey, Michael L. Freedman · 1994 · The American Journal of the Medical Sciences
  38. Bioenergetic medicine
    Russell Howard Swerdlow · 2013 · British Journal of Pharmacology
  39. Association study of two genetic variants in mitochondrial transcription factor A (TFAM) in Alzheimer's and Parkinson's disease
    Belin, Andrea Carmine, Björk, Behnosh F., Westerlund, Marie, Galter, Dagmar, Sydow, Olof, Lind, Charlotta, Pernold, Karin, Rosvall, Lina, Håkansson, Anna, Winblad, Bengt et al. · 2007 · Neuroscience Letters
  40. Glycolysis–respiration relationships in a neuroblastoma cell line
    Russell Howard Swerdlow, E Lezi, Daniel Aires, Jianghua Lu · 2013 · Biochimica et Biophysica Acta (BBA) - General Subjects
  41. Variability of age at onset in siblings with familial Alzheimer disease
    Gómez-Tortosa, Estrella, Barquero, M. Sagrario, Barón, Manuel, Sainz, M. Jose, Manzano, Sagrario, Payno, Maria, Ros, Raquel, Almaraz, Carmen, Gómez-Garré, Pilar, Jiménez-Escrig, Adriano · 2007 · Archives of Neurology
  42. Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formation
    Pinto, Milena, Pickrell, Alicia M., Fukui, Hirokazu, Moraes, Carlos T. · 2013 · Neurobiology of Aging
  43. Effects of age on the glucose metabolic changes in mild cognitive impairment
    Kantarci, K., Senjem, M.L., Lowe, V.J., Wiste, H.J., Weigand, S.D., Kemp, B.J., Frank, A.R., Shiung, M.M., Boeve, B.F., Knopman, D.S. et al. · 2010 · American Journal of Neuroradiology
  44. Brain Oxidative Energy and Related Metabolism, Neuronal Stress, and Alzheimer's Disease: A Speculative Synthesis
    Siegfried Hoyer · 1993 · Journal of Geriatric Psychiatry and Neurology
  45. Oxidative stress and amyloid-beta pathology in normal individuals with a maternal history of Alzheimer's
    Mosconi, Lisa, Glodzik, Lidia, Mistur, Rachel, McHugh, Pauline, Rich, Kenneth E., Javier, Elizabeth, Williams, Schantel, Pirraglia, Elizabeth, De Santi, Susan, Mehta, Pankaj D. et al. · 2010 · Biological Psychiatry
  46. Elevated levels of the Kearns–Sayre syndrome mitochondrial DNA deletion in temporal cortex of Alzheimer's patients
    Hamblet, Natasha S, Castora, Frank J · 1997 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  47. Incidence of dementia in very elderly individuals: a clinical, neuropathological and molecular genetic study
    Polvikoski, Tuomo, Sulkava, Raimo, Rastas, Sari, Sutela, Annamaija, Niinistö, Leena, Notkola, Irma-Leena, Verkkoniemi, Auli, Viramo, Petteri, Juva, Kati, Haltia, Matti · 2006 · Neuroepidemiology
  48. Mitochondrial medicine and the neurodegenerative mitochondriopathies
    Swerdlow, Russell H. · 2009 · Pharmaceuticals
  49. Do Haplogroups H and U Act to Increase the Penetrance of Alzheimer’s Disease?
    Farzaneh Fesahat, Massoud Houshmand, Mehdi Shafa Shariat Panahi, Kurosh Gharagozli, Farzaneh Mirzajani · 2006 · Cellular and Molecular Neurobiology
  50. The Outcome of Elderly Patients with Cognitive Complaints but Normal Neuropsychological Tests
    Teresa Nunes, Isabel Fragata, Filipa Ribeiro, Teresa Palma, João Paulo Marôco, Jorge Cannas, Mário Forjaz Secca, Cristina Miranda Menezes, Isabel Carmo, Gil Cunha et al. · 2010 · Journal of Alzheimer s Disease
  51. Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA)
    Brown, Abraham M., Sheu, Rex K.-F., Mohs, Richard, Haroutunian, Vahram, Blass, John P. · 2001 · Journal of Molecular Neuroscience
  52. Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases
    H. Swerdlow, Russell · 2011 · Current Pharmaceutical Design
  53. Polymorphic variation in cytochrome oxidase subunit genes
    Lu, Jianghua, Wang, Kaixuan, Rodova, Mariana, Esteves, Raquel, Berry, Diana, E, Lezi, Crafter, Adam, Barrett, Matthew, Cardoso, Sandra M., Onyango, Isaac et al. · 2010 · Journal of Alzheimer s Disease
  54. Prodromal Metabolic Phenotype in MCI Cybrids: Implications for Alzheimer’s Disease
    F. Silva, D., Santana, I., R. Esteves, A., Baldeiras, I., M. Arduino, D., R. Oliveira, C., M. Cardoso, S. · 2013 · Current Alzheimer Research
  55. P2‐033: Plasma amyloid‐beta as a predictor of dementia and cognitive decline: A systematic review and meta‐analysis
    Alain K. Koyama, Olivia I. Okereke, Ting Yang, Dennis J. Selkoe, Francine Grodstein · 2011 · Alzheimer s & Dementia
  56. TOMM40 Association With Alzheimer Disease
    Rita João Guerreiro, John Hardy · 2012 · Archives of Neurology
  57. TOMM40 intron 6 poly‐T length, age at onset, and neuropathology of AD in individuals with APOE ɛ3/ɛ3
    Ge Li, Lynn M. Bekris, Lesley Leong, Ellen J. Steinbart, Jane B. Shofer, Paul K. Crane, Eric Berg Larson, Elaine R. Peskind, Thomas D. Bird, Chang‐En Yu · 2012 · Alzheimer s & Dementia
  58. Mitochondrial Haplotypes Associated with Biomarkers for Alzheimer’s Disease
    Perry G. Ridge, Andre Koop, Taylor J. Maxwell, Matthew H. Bailey, Russell Howard Swerdlow, John S. K. Kauwe, Robyn A. Honea, Alzheimer’s Disease Neuroimaging Initiative · 2013 · PLoS ONE
  59. Mitochondrial transcription factor A (TFAM) gene variation and risk of late-onset Alzheimer's disease
    Alvarez, Victoria, Corao, Ana I., Alonso-Montes, Cristina, Sánchez-Ferrero, Elena, De Mena, Lorena, Morales, Blanca, García-Castro, Mónica, Coto, Eliecer · 2008 · Journal of Alzheimer s Disease
  60. May “Mitochondrial Eve” and Mitochondrial Haplogroups Play a Role in Neurodegeneration and Alzheimer′s Disease?
    Elena Caldarazzo Ienco, Costanza Simoncini, Daniele Orsucci, Loredana Petrucci, Massimiliano Filosto, Michelangelo Mancuso, Gabriele Siciliano · 2011 · International Journal of Alzheimer s Disease
  61. Nerve growth factor attenuates oxidant‐induced β‐amyloid neurotoxicity in sporadic Alzheimer’s disease cybrids
    Onyango, Isaac G., Ahn, Jin‐Young, Tuttle, Jeremy B., Bennett Jr, James P., Swerdlow, Russell H. · 2010 · Journal of Neurochemistry
  62. Mitochondrial haplogroups associated with Japanese Alzheimer’s patients
    Shigeru Takasaki · 2009 · Journal of Bioenergetics and Biomembranes
  63. Longitudinal studies of cerebral glucose metabolism in late-life depression and normal aging
    Marano, Christopher M., Workman, Clifford I., Kramer, Elisse, Hermann, Carol R., Ma, Yilong, Dhawan, Vijay, Chaly, Thomas, Eidelberg, David, Smith, Gwenn S. · 2013 · International Journal of Geriatric Psychiatry
  64. Cognitively normal individuals with AD parents may be at risk for developing aging-related cortical thinning patterns characteristic of AD
    Katherine E Reiter, Kathryn I. Alpert, Derin J. Cobia, Mary Kwasny, John C. Morris, John G. Csernansky, Lei Wang · 2012 · NeuroImage
  65. Widespread γ-secretase activity in the cell, but do we need it at the mitochondria?
    Teng, Felicia Yu Hsuan, Tang, Bor Luen · 2005 · Biochemical and Biophysical Research Communications
  66. A Cross‐Sectional Study on Cerebrospinal Fluid Biomarker Levels in Cognitively Normal Elderly Subjects With or Without a Family History of Alzheimer's Disease
    Zhao Liu, Huaihong Chen, Tianlang Li, Lei Xu, Hua‐Qing Du · 2012 · CNS Neuroscience & Therapeutics
  67. Functional expressions of the aging brain: Nutrition Reviews©, Vol. 68, No. s2
    Folstein, Marshal, Folstein, Susan · 2010 · Nutrition Reviews
  68. Prevalence of dementia after age 90: Results from The 90+ Study
    Corrada, M. M., Brookmeyer, R., Berlau, D., Paganini-Hill, A., Kawas, C. H. · 2008 · Neurology
  69. Colombia at the centre of preclinical AD research
    The Lancet Neurology · 2012 · The Lancet Neurology
  70. If we live long enough, will we all be demented?
    David B. Hogan · 2008 · Neurology
  71. Backwaters and rapids on the amyloid river
    Burns, Jeffrey M., Swerdlow, Russell H. · 2013 · Neurology
  72. IC‐P‐101: Increased cerebral blood flow in cognitively normal older adults with amyloid
    Aaron P. Schultz, Donald G. McLaren, Jasmeer P. Chhatwal, Karleyton C. Evans, Keith A. Johnson, Reisa Anne Sperling · 2013 · Alzheimer s & Dementia
  73. Predictors of Preclinical Alzheimer Disease and Dementia: A Clinicopathologic Study
    Galvin, James E., Powlishta, Kimberly K., Wilkins, Kenneth, McKeel, Daniel W., Xiong, Chengjie, Grant, Elizabeth, Storandt, Martha, Morris, John C. · 2005 · Archives of Neurology
  74. P2–129: Region‐specific associations of brain glucose metabolism with age and beta‐amyloid deposition in normal aging
    Hwamee Oh, Cindee M. Madison, Suzanne L. Baker, William J. Jagust · 2013 · Alzheimer s & Dementia
  75. Untitled work
    Khan · 2000 · 10.1002/1531-8249(200008)48:2