Cited by 55Neuroendocrine regulation and behaviorFace Recognition and PerceptionNeural and Behavioral Psychology Studies

Oxytocin effects on neural correlates of self-referential processing

Liu, Yi, Sheng, Feng, Woodcock, Kate A., Han, Shihui·2013·Biological Psychology

Abstract

Oxytocin (OT) influences how humans process information about others. Whether OT affects the processing of information about oneself remains unknown. Using a double-blind, placebo-controlled within-subject design, we recorded event-related potentials (ERPs) from adults during trait judgments about oneself and a celebrity and during judgments on word valence, after intranasal OT or placebo administration. We found that OT vs. placebo treatment reduced the differential amplitudes of a fronto-central positivity at 220-280 ms (P2) during self- vs. valence-judgments. OT vs. placebo treatment tended to reduce the differential amplitude of a late positive potential at 520-1000 ms (LPP) during self-judgments but to increase the differential LPP amplitude during other-judgments. OT effects on the differential P2 and LPP amplitudes to self- vs. celebrity-judgments were positively correlated with a measure of interdependence of self-construals. Thus OT modulates the neural correlates of self-referential processing and this effect varies as a function of interdependence.

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Crossref · 10.1016/j.biopsycho.2013.08.003

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Authors
Liu, Y., Sheng, F., Woodcock, K. A., & Han, S.
Affiliations
Peking University (CN)
Corresponding author
Han, Shihui
Venue
Biological Psychology
Publisher
Elsevier BV
Published
2013-10
Volume
94
Issue
2
Pages
380-387
ISSN
0301-0511 (ISSN-L)
OpenAlex
W2165708796
Cited by
55
References
66
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 3 · 2020: 8 · 2019: 7 · 2018: 2 · 2017: 6 · 2016: 8 · 2015: 5 · 2014: 3
FWCI
7.99
Type
journal article
Language
en
Open access
closed
Locations
  • Biological Psychology (publishedVersion)
  • PubMed (publishedVersion)
  • University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
  • Research Portal (Queen's University Belfast) (submittedVersion)
Funders
  • Beijing Municipal Natural Science Foundation (Z111107067311058)
  • National Key Research and Development Program of China (2010CB833903)
  • National Natural Science Foundation of China (91224008, 81161120539, 91024032)
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
oxytocin, self-referential processing, self-construal, interdependence, trait judgments, word valence, P2 component, late positive potential, event-related potentials, social cognition, intranasal administration
MeSH terms
Administration, Intranasal, Analysis of Variance, Brain Mapping, Double-Blind Method, Electroencephalography, Evoked Potentials, Humans, Judgment, Male, Oxytocics, Oxytocin, Reaction Time, Self Concept, Social Perception, Young Adult

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